Hydroxyl radical production in the cortex and striatum in a rat model of focal cerebral ischemia

Canadian Journal of Neurological Sciences

Volumn 27, Issue 2, 2000, Pages 152-159

  Ste Marie, Line ^a   Vachon, Pascal ^b   Vachon, Luc ^a   Bémeur, Chantal ^a   Guertin, Marie Claude ^d   Montgomery, Jane ^a,c  

^a UNIVERSITÉ DE MONTRÉAL   (Canada)

^b MDS Inc   (Canada)

^c NOTRE DAME HOSPITAL   (Canada)

^d NONE

Author keywords

[No Author keywords available]

Indexed keywords

3,4 DIHYDROXYPHENYLACETIC ACID; 4 HYDROXYBENZOIC ACID; 5 HYDROXYINDOLEACETIC ACID; DOPAMINE; HOMOVANILLIC ACID; HYDROXYL RADICAL;

ANIMAL MODEL; ARTICLE; BRAIN BLOOD FLOW; BRAIN CORTEX; BRAIN INFARCTION; BRAIN ISCHEMIA; BRAIN TEMPERATURE; CONTROLLED STUDY; CORPUS STRIATUM; DOPAMINE RELEASE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HYDROXYLATION; MALE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; RAT;

EID: 0034084073     PISSN: 03171671     EISSN: None     Source Type: Journal    
DOI: 10.1017/s0317167100052276     Document Type: Article

References (52)

1. Siesjö BK. Pathophysiology and treatment of focal cerebral ischemia. Part II: Mechanisms of damage and treatment. J Neurosurg 1992;77:337-354.
2. Siesjö BK. Pathophysiology and treatment of focal ischemia. Part I: Pathophysiology. J Neurosurg 1992;77:169-184.
3. Choi DW, Rothman SM. The role of glutamate neurotoxicity in hypoxic-ischemic neuronal death. Annu Rev Neurosci 1990;13:171-182.
4. Lancelot E, Callebert J, Revaud M-L, et al. Detection of hydroxyl radicals in rat striatum during transient focal cerebral ischemia: possible implication in tissue damage. Neurosci Lett 1995;197:85-88.
5. Morimoto T, Globus MYT, Busto R, et al. Simultaneous measurement of salicylate hydroxylation and glutamate release in the penumbral cortex following transient middle cerebral artery occlusion in rats. J Cereb Blood Flow Metab 1996;16:92-99.
6. Wei J, Huang NC, Quast MJ. Hydroxyl radical formation in hyperglycemic rats during middle cerebral artery occlusion/reperfusion. Free Radic Biol Med 1997;23:986-995.
7. Yang C-S, Lin N-N, Tsai P-J, et al. In vivo evidence of hydroxyl radical formation induced by elevation of extracellular glutamate after cerebral ischemia in the cortex of anesthetized rats. Free Radic Biol Med 1996;20:245-250.
8. Wei J, Quast MJ. Effect of nitric oxide synthase inhibitor on a hyperglycemic rat model of reversible focal ischemia: detection of excitatory amino acids release and hydroxyl radical formation. Brain Res 1998;791:146-156.
9. Solenski NJ, Kwan A-L, Yanamoto H, et al. Differential hydroxylation of salicylate in core and penumbra regions during focal reversible cerebral ischemia. Stroke 1997;28:2545-2552.
10. 2 production in the rat striatum following transient middle cerebral artery occlusion. Brain Res 1997;764:299-302.
11. Landolt H, Lutz TW, Langemann H, et al. Extracellular antioxidants and amino acids in the cortex of the rat: monitoring by microdialysis of early ischemic changes. J Cereb Blood Flow Metab 1992;12:96-102.
12. Uemura Y, Miller JM, Matson WR, et al. Neurochemical analysis of focal ischemia in rats. Stroke 1991;22:1548-1553.
13. Piantadosi CA, Zhang J. Mitochondrial generation of reactive oxygen species after brain ischemia in the rat. Stroke 1996;27:327-332.
14. Yamamoto T, Yuki S, Watanabe T, et al. Delayed neuronal death prevented by inhibition of increased hydroxyl radical formation in a transient cerebral ischemia. Brain Res 1997;762:240-242.
15. Zhang J, Piantadosi CA. Prolonged production of hydroxyl radical in rat hippocampus after brain ischemia-reperfusion is decreased by 21-aminosteroids. Neurosci Lett 1994;177:127-130.
16. Althaus JS, Andrus PK, Williams CM, et al. The use of salicylate hydroxylation to detect hydroxyl radical generation in ischemic and traumatic brain injury. Mol Chem Neuropathol 1993;20:147-162.
17. Hall ED, Andrus PK, Althaus JS, et al. Hydroxyl radical production and lipid peroxidation parallels selective post-ischemic vulnerability in gerbil brain. J Neurosci Res 1993;34:107-112.
18. Spinnewyn B, Cornet S, Auguet M, et al. Synergistic protective effects of antioxidant and nitric oxide synthase inhibitor in transient focal ischemia. J Cereb Blood Flow Metab 1999;19:139-143.
19. +. Free Radic Biol Med 1992;13:581-583.
20. Chiueh CC, Wu, Mohanakumar KP, et al. In vivo generation of hydroxyl radicals and MPTP-induced dopaminergic toxicity in the basal ganglia. Ann N Y Acad Sci 1994;738:25-36.
21. Globus MYT, Ginsberg MD, Dietrich WD, et al. Substantia nigra lesion protects against ischemic damage in the striatum. Neurosci Lett 1987;80:251-256.
22. Ren Y, Li X, Xu ZC. Asymmetrical protection of neostriatal neurons against transient forebrain ischemia by unilateral dopamine depletion. Exp Neurol 1997;146:250-257.
23. Ste-Marie L, Boismenu D, Vachon L, et al. Evaluation of sodium 4-hydroxybenzoate as an hydroxyl radical trap using gas chromatography-mass spectrometry and high-performance liquid chromatography with electrochemical detection. Anal Biochem 1996;67-74.
24. Bogdanov MB, Ramos LE, Xu Z, et al. Elevated "hydroxyl radical" generation in vivo in an animal model of amyotrophic lateral sclerosis. J Neurochem 1998;71:1321-1324.
25. Montgomery J, Ste-Marie L, Boismenu D, et al. Hydroxylation of aromatic compounds as indices of hydroxyl radical production: a cautionary note revisited. Free Radic Biol Med 1995;19:927-933.
26. Paxinos G, Watson C. The rat brain in stereotaxic co-ordinates. Toronto, Academic Press, 1986.
27. Chen ST, Hsu CY, Hogan EL, et al. A model of focal ischemic stroke in the rat: reproducible extensive cortical infarction. Stroke 1986;17:738-743.
28. Buchan AM, Xue D, Slivka A. A new model of temporary focal ischemia in the rat. Stroke 1992;23:273-279.
29. Bederson JB, Pitts LH, Germano SM, et al. Evaluation of 2.3.5-triphenyltetrazolium chloride as a stain for detection and quantification of experimental cerebral infarction in rats. Stroke 1986;17:1304-1308.
30. Floyd RA, Watson JJ, Wong PK. Sensitive assay of hydroxyl free radical formation utilizing high-performance liquid chromatography with electrochemical detection of phenol and salicylate hydroxylation products. J Biochem Biophys Methods 1984;10:221-235.
31. Grootveld M, Halliwell B. Aromatic hydroxylation as a potential measure of hydroxyl-radical formation in vivo. Biochem J 1986;237:499-504.
32. + does not result in increased hydroxylation after systemic administration of 4-hydroxybenzoate. Free Radic Biol Med 1999;27:997-1007.
33. Globus MYT, Ginsberg MD, Schnippering H, et al. Detection of free radical activity during ischemia by salicylate trapping and microdialysis. Stroke 1994;25:254-254.
34. Hillered L, Hallstrom A, Segersvard S, et al. Dynamics of extracellular metabolites in the striatum after middle cerebral artery occlusion in the rat monitored by intracerebral microdialysis. J Cereb Blood Flow Metab 1989;9:607-616.
35. Wood ER, Coury A, Blaha CD, et al. Extracellular dopamine in the rat striatum during ischemia and reperfusion as measured by in vivo electrochemistry and in vivo microdialysis. Brain Res 1992;591:151-159.
36. Akiyama Y, Ito A, Koshimura K, et al. Effects of transient forebrain ischemia and reperfusion on function of dopaminergic neurons and dopamine reuptake in vivo in rat striatum. Brain Res 1991;561:120-127.
37. 2 receptors. J Neurochem 1993;60:1483-1490.
38. Damsma G, Boisvert DP, Mudrick LA, et al. Effects of transient forebrain ischemia and pargyline on extracellular concentrations of dopamine, serotonin, and their metabolites in the rat striatum as determined by in vivo microdialysis. J Neurochem 1990;54:801-808.
39. Obrenovitch TP, Richards DA. Extracellular neurotransmitter changes in cerebral ischemia. Cerebrovas Brain Metab Rev 1995; 7:1-54.
40. +. J Neural Transm 1992;89:139-145.
41. Clemens JA, Phebus LA. Dopamine depletion protects striatal neurons from ischemia-induced cell death. Life Sci 1988;42:707-713.
42. Spranger M, Krempien S, Schwab S, et al. Superoxide dismutase activity in serum of patients with acute cerebral ischemic injury. Correlation with clinical course and infarct size. Stroke 1997;28:2425-2428.
43. Sutherland GR, Bose R, Louw DF, et al. Global elevation of brain superoxide dismutase activity following forebrain ischemia in rat. Neurosci Lett 1991;128:169-172.
44. Matsumiya N, Koehler RC, Kirsch JR, et al. Conjugated superoxide dismutase reduces extent of caudate injury after transient focal ischemia in cats. Stroke 1991;22:1193-1200.
45. Kondo T, Reaume AG, Huang T-T, et al. Reduction of CuZn-superoxide dismutase activity exacerbates neuronal cell injury and edema formation after transient focal cerebral ischemia. J Neurosci 1997;17:4180-4189.
46. Murakami K, Kondo T, Kawase M, et al. Mitochondrial susceptibility to oxidative stress exacerbates cerebral infarction that follows permanent focal cerebral ischemia in mutant mice with manganese superoxide dismutase deficiency. J Neurosci 1998;18:205-213.
47. 2 production during ischemia and reperfusion: a microdialysis study in the gerbil hippocampus. Neurosci Lett 1997;222:91-94.
48. Malinski T, Zhang ZG, et al. Nitric oxide measured by a porphyrinic microsensor in rat brain after transient middle cerebral artery occlusion. J Cereb Blood Flow Mctab 1993;13:355-358.
49. Kader A, Frazzini VI, Solomon RA, et al. Nitric oxide production during focal cerebral ischemia in rats. Stroke 1993;24:1709-1716.
50. Keller JN, Kindy MS, Holtsberg FW, et al. Mitochondrial manganese superoxide dismutase prevents neural apoptosis and reduces ischemic brain injury: suppression of peroxynitrite production, lipid peroxidation, and mitochondrial dysfunction. J Neurosci 1998;18:687-697.
51. Coeroli L, Arnaud RS, Plotkine D, et al. Nitric oxide production and perivascular tyrosine nitration following focal ischemia in neonatal rat. J Neurochem 1998;70:2516-2525.
52. Koppenol WH. The basic chemistry of nitrogen monoxide and peroxynitrite. Free Radic Biol Med 1998;25:385-391.