Effect of nitric oxide synthase inhibitor on a hyperglycemic rat model of reversible focal ischemia: Detection of excitatory amino acids release and hydroxyl radical formation

Brain Research

Volumn 791, Issue 1-2, 1998, Pages 146-156

  Wei, Jingna ^a   Quast, Michael J ^a,b  

^a UNIVERSITY OF TEXAS MEDICAL BRANCH   (United States)

^b University of Texas Medical Branch School of Medicine   (United States)

Author keywords

Cerebral ischemia; Glutamate; Hydroxyl radical; Hyperglycemia; Magnetic resonance imaging; Nitric oxide; NOS inhibitor; Reperfusion; Superparamagnetic iron oxide

Indexed keywords

2,3 DIHYDROXYBENZOIC ACID; ARGININE; ASPARTIC ACID; CITRULLINE; EXCITATORY AMINO ACID; EXCITOTOXIN; GENTISIC ACID; GLUCOSE; GLUTAMIC ACID; HYDROXYL RADICAL; N(G) NITROARGININE METHYL ESTER; NITRIC OXIDE DONOR; NITRIC OXIDE SYNTHASE INHIBITOR; SALICYLIC ACID; SUPERPARAMAGNETIC IRON OXIDE; ULTRASMALL SUPERPARAMAGNETIC IRON OXIDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN ISCHEMIA; BRAIN PERFUSION; CONTROLLED STUDY; DRUG EFFECT; DRUG MECHANISM; HYPERGLYCEMIA; INTRAPERITONEAL DRUG ADMINISTRATION; MALE; MICRODIALYSIS; MIDDLE CEREBRAL ARTERY OCCLUSION; NEUROPROTECTION; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; PRIORITY JOURNAL; RAT; REPERFUSION INJURY;

ANIMALS; CELL SURVIVAL; CITRULLINE; DISEASE MODELS, ANIMAL; DRUG EVALUATION, PRECLINICAL; ENZYME INHIBITORS; GLUTAMIC ACID; HYDROXYL RADICAL; HYPERGLYCEMIA; ISCHEMIC ATTACK, TRANSIENT; MAGNETIC RESONANCE IMAGING; MALE; NEUROPROTECTIVE AGENTS; NG-NITROARGININE METHYL ESTER; NITRIC OXIDE SYNTHASE; RATS; RATS, SPRAGUE-DAWLEY;

EID: 0032571790     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-8993(98)00089-4     Document Type: Article

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