메뉴 건너뛰기




Volumn 7, Issue 3, 2000, Pages 140-146

Inhaled drug therapy during mechanical ventilation

Author keywords

Aerosols; Bronchodilators; Inhalation therapy; Mechanical ventilation; Vasodilators

Indexed keywords

ACETYLCYSTEINE; ANTIBIOTIC AGENT; BETA ADRENERGIC RECEPTOR STIMULATING AGENT; BRONCHODILATING AGENT; CHOLINERGIC RECEPTOR BLOCKING AGENT; DORNASE ALFA; HELIUM; IPRATROPIUM BROMIDE; MUCOLYTIC AGENT; NITRIC OXIDE; PROSTACYCLIN; PROSTAGLANDIN; SALBUTAMOL; SURFACTANT;

EID: 0034081055     PISSN: 10680640     EISSN: None     Source Type: Journal    
DOI: 10.1097/00045413-200007030-00005     Document Type: Article
Times cited : (1)

References (51)
  • 1
    • 0030845450 scopus 로고    scopus 로고
    • Inhaled bronchodilator therapy in mechanically ventilated patients
    • Dhand R, Tobin MJ. Inhaled bronchodilator therapy in mechanically ventilated patients. Am J Respir Crit Care Med 1997;156:3-10.
    • (1997) Am J Respir Crit Care Med , vol.156 , pp. 3-10
    • Dhand, R.1    Tobin, M.J.2
  • 2
    • 0032900977 scopus 로고    scopus 로고
    • Reconciling in vitro and in vivo measurements of aerosol delivery from a metered-dose inhaler during mechanical ventilation and defining efficiency-enhancing factors
    • Fink JB, Dhand R, Grychowski J, Fahey PJ, Tobin MJ. Reconciling in vitro and in vivo measurements of aerosol delivery from a metered-dose inhaler during mechanical ventilation and defining efficiency-enhancing factors. Am J Respir Crit Care Med 1999;159:63-8.
    • (1999) Am J Respir Crit Care Med , vol.159 , pp. 63-68
    • Fink, J.B.1    Dhand, R.2    Grychowski, J.3    Fahey, P.J.4    Tobin, M.J.5
  • 3
    • 0025786083 scopus 로고
    • Clinical aspects of aerosol physics
    • Dolovich M. Clinical aspects of aerosol physics. Respir Care 1991;9:931-8.
    • (1991) Respir Care , vol.9 , pp. 931-938
    • Dolovich, M.1
  • 4
    • 0028147668 scopus 로고
    • Efficiency of bronchodilator aerosol delivery to the lungs from metered-dose inhaler in mechanically ventilated patients: A study comparing four different actuator devices
    • Fuller HD, Dolovich MB, Turpie FH, Newhouse MT. Efficiency of bronchodilator aerosol delivery to the lungs from metered-dose inhaler in mechanically ventilated patients: a study comparing four different actuator devices. Chest 1994;105:214-8.
    • (1994) Chest , vol.105 , pp. 214-218
    • Fuller, H.D.1    Dolovich, M.B.2    Turpie, F.H.3    Newhouse, M.T.4
  • 5
    • 0031739626 scopus 로고    scopus 로고
    • A comparison of inline MDI actuators for delivery of a β agonist and a corticosteroid with a mechanically ventilated lung model
    • Rau JL, Dunlevy CL, Hill RL. A comparison of inline MDI actuators for delivery of a β agonist and a corticosteroid with a mechanically ventilated lung model. Respir Care 1998;43:705-12.
    • (1998) Respir Care , vol.43 , pp. 705-712
    • Rau, J.L.1    Dunlevy, C.L.2    Hill, R.L.3
  • 6
    • 0026543068 scopus 로고
    • Substitution of metered-dose inhalers for hand held nebulizers: Success and cost savings in a large, acute care hospital
    • Bowton DL, Goldsmith WM, Haponik EF. Substitution of metered-dose inhalers for hand held nebulizers: success and cost savings in a large, acute care hospital. Chest 1992;101:305-8.
    • (1992) Chest , vol.101 , pp. 305-308
    • Bowton, D.L.1    Goldsmith, W.M.2    Haponik, E.F.3
  • 7
    • 0029023296 scopus 로고
    • An outbreak of Burkholderia (formerly Pseudomonas) cepacia respiratory tract colonization and infection associated with nebulized albuterol therapy
    • Hamill RJ, Houston ED, Georghiou PR, et al. An outbreak of Burkholderia (formerly Pseudomonas) cepacia respiratory tract colonization and infection associated with nebulized albuterol therapy. Ann Intern Med 1995;122:762-6.
    • (1995) Ann Intern Med , vol.122 , pp. 762-766
    • Hamill, R.J.1    Houston, E.D.2    Georghiou, P.R.3
  • 8
    • 0025837892 scopus 로고
    • Effects of albuterol inhalation on the work of breathing during weaning from mechanical ventilation
    • Mancebo J, Amaro P, Lorino H, Lemaire F, Harf A, Brochard L. Effects of albuterol inhalation on the work of breathing during weaning from mechanical ventilation. Am Rev Respir Dis 1991;144:95-100.
    • (1991) Am Rev Respir Dis , vol.144 , pp. 95-100
    • Mancebo, J.1    Amaro, P.2    Lorino, H.3    Lemaire, F.4    Harf, A.5    Brochard, L.6
  • 9
    • 0027770791 scopus 로고
    • Metered-dose inhaler versus nebulized albuterol in mechanically ventilated patients
    • Manthous CA, Hall JB, Schmidt GA, Wood LDH. Metered-dose inhaler versus nebulized albuterol in mechanically ventilated patients. Am Rev Respir Dis 1993;148:1567-70.
    • (1993) Am Rev Respir Dis , vol.148 , pp. 1567-1570
    • Manthous, C.A.1    Hall, J.B.2    Schmidt, G.A.3    Wood, L.D.H.4
  • 10
    • 0029781461 scopus 로고    scopus 로고
    • Dose response to bronchodilator delivered by meter-dose inhaler in ventilator-supported patients
    • Dhand R, Duarte AG, Jubran A, et al. Dose response to bronchodilator delivered by meter-dose inhaler in ventilator-supported patients. Am J Respir Crit Care Med 1996;154:388-93.
    • (1996) Am J Respir Crit Care Med , vol.154 , pp. 388-393
    • Dhand, R.1    Duarte, A.G.2    Jubran, A.3
  • 11
    • 0028090587 scopus 로고
    • Effect of bronchodilators on lung mechanics in the acute respiratory distress syndrome (ARDS)
    • Wright PE, Carmichael LC, Bernard GR. Effect of bronchodilators on lung mechanics in the acute respiratory distress syndrome (ARDS). Chest 1994;106:1517-23.
    • (1994) Chest , vol.106 , pp. 1517-1523
    • Wright, P.E.1    Carmichael, L.C.2    Bernard, G.R.3
  • 12
    • 0006580313 scopus 로고    scopus 로고
    • Response to salmeterol delivered by metered-dose inhaler in ventilator-supported patients
    • Navin D, Dhand R, Fink J, Fahey PJ, Tobin MJ. Response to salmeterol delivered by metered-dose inhaler in ventilator-supported patients [abstract]. Am J Respir Crit Care Med 1997:155:A771.
    • (1997) Am J Respir Crit Care Med , vol.155
    • Navin, D.1    Dhand, R.2    Fink, J.3    Fahey, P.J.4    Tobin, M.J.5
  • 13
    • 0028231507 scopus 로고
    • Comparison of one versus two bronchodilators in ventilated COPD patients
    • Fernandez A, Munoz J, de la Calle B, et al. Comparison of one versus two bronchodilators in ventilated COPD patients. Intensive Care Med 1994;20:199-202.
    • (1994) Intensive Care Med , vol.20 , pp. 199-202
    • Fernandez, A.1    Munoz, J.2    De La Calle, B.3
  • 14
    • 0032938330 scopus 로고    scopus 로고
    • Inhaled fenoterol-ipratropium bromide in mechanically ventilated patients with chronic obstructive pulmonary disease
    • Guerin C, Chevre A, Dessirier P, et al. Inhaled fenoterol-ipratropium bromide in mechanically ventilated patients with chronic obstructive pulmonary disease. Am J Respir Crit Care Med 1999;159:1036-42.
    • (1999) Am J Respir Crit Care Med , vol.159 , pp. 1036-1042
    • Guerin, C.1    Chevre, A.2    Dessirier, P.3
  • 16
    • 0030927781 scopus 로고    scopus 로고
    • Nebuliser therapy in the intensive care unit
    • O'Doherty MJ, Thomas SHL. Nebuliser therapy in the intensive care unit. Thorax 1997; 52(Suppl 2):S56-S59.
    • (1997) Thorax , vol.52 , Issue.2 SUPPL.
    • O'Doherty, M.J.1    Thomas, S.H.L.2
  • 17
    • 0001492676 scopus 로고    scopus 로고
    • Does placement of nebulizer before the humidifier improve aerosol delivery during mechanical ventilation?
    • Fink JB, Varshney R, Goode M, Fahey PJ, Tobin MJ, Dhand R. Does placement of nebulizer before the humidifier improve aerosol delivery during mechanical ventilation? [abstract]. Am J Respir Crit Care Med 1999;159:A86.
    • (1999) Am J Respir Crit Care Med , vol.159
    • Fink, J.B.1    Varshney, R.2    Goode, M.3    Fahey, P.J.4    Tobin, M.J.5    Dhand, R.6
  • 18
    • 0028873969 scopus 로고
    • Effect of a spacer-on pulmonary aerosol deposition from a jet nebuliser during mechanical ventilation
    • Harvey CJ, O'Doherty MJ, Page CJ, Thomas SHL, Nunan TO, Treacher DF. Effect of a spacer-on pulmonary aerosol deposition from a jet nebuliser during mechanical ventilation. Thorax 1995;50:50-3.
    • (1995) Thorax , vol.50 , pp. 50-53
    • Harvey, C.J.1    O'Doherty, M.J.2    Page, C.J.3    Thomas, S.H.L.4    Nunan, T.O.5    Treacher, D.F.6
  • 19
    • 0023473104 scopus 로고
    • Effects of nebulizer mode and position in a mechanical ventilator circuit on dose efficiency
    • Hughes JM, Saez J. Effects of nebulizer mode and position in a mechanical ventilator circuit on dose efficiency. Respir Care 1987;32:1131-5.
    • (1987) Respir Care , vol.32 , pp. 1131-1135
    • Hughes, J.M.1    Saez, J.2
  • 20
    • 0028103867 scopus 로고
    • Proximate delivery of a large experimental dose from salbutamol MDI induces epithelial airway lesions in intubated rabbits
    • Spahr-Schopfer IA, Lerman J, Cutz E, Newhouse MT, Dolovich M. Proximate delivery of a large experimental dose from salbutamol MDI induces epithelial airway lesions in intubated rabbits. Am J Respir Crit Care Med 1994;150:790-4.
    • (1994) Am J Respir Crit Care Med , vol.150 , pp. 790-794
    • Spahr-Schopfer, I.A.1    Lerman, J.2    Cutz, E.3    Newhouse, M.T.4    Dolovich, M.5
  • 21
    • 0023264362 scopus 로고
    • The effects of vasodilation with prostacyclin on oxygen delivery and uptake in critically ill patients
    • Bihari D, Smithies M, Gimson A, et al. The effects of vasodilation with prostacyclin on oxygen delivery and uptake in critically ill patients. N Engl J Med 1987;317:397-402.
    • (1987) N Engl J Med , vol.317 , pp. 397-402
    • Bihari, D.1    Smithies, M.2    Gimson, A.3
  • 22
    • 0029880173 scopus 로고    scopus 로고
    • Direct comparison of inhaled nitric oxide and aerosolized prostacyclin in adult respiratory distress syndrome
    • Walmrath D, Schneider T, Schermuly R, et al. Direct comparison of inhaled nitric oxide and aerosolized prostacyclin in adult respiratory distress syndrome. Am J Respir Crit Care 1996;153:991-6.
    • (1996) Am J Respir Crit Care , vol.153 , pp. 991-996
    • Walmrath, D.1    Schneider, T.2    Schermuly, R.3
  • 23
    • 0030339154 scopus 로고    scopus 로고
    • Inhaled prostacyclin versus inhaled nitric oxide in adult respiratory distress syndrome
    • Zwissler B, Kemming G, Habler O, et al. Inhaled prostacyclin versus inhaled nitric oxide in adult respiratory distress syndrome. Am J Respir Crit Care Med 1996;154:1671-77.
    • (1996) Am J Respir Crit Care Med , vol.154 , pp. 1671-1677
    • Zwissler, B.1    Kemming, G.2    Habler, O.3
  • 24
    • 0031863568 scopus 로고    scopus 로고
    • Cardiopulmonary effects of aerosolized prostaglandin E1 and nitric oxide inhalation in patients with acute respiratory distress syndrome
    • Putensen C, Hormann C, Kleinsasser A, Putesen-Himmer G. Cardiopulmonary effects of aerosolized prostaglandin E1 and nitric oxide inhalation in patients with acute respiratory distress syndrome. Am J Respir Crit Care Med 1998;157:1743-7.
    • (1998) Am J Respir Crit Care Med , vol.157 , pp. 1743-1747
    • Putensen, C.1    Hormann, C.2    Kleinsasser, A.3    Putesen-Himmer, G.4
  • 26
    • 0027455571 scopus 로고
    • State of the art: Surfactant and the adult respiratory distress syndrome
    • Lewis JF, Jobe AH. State of the art: surfactant and the adult respiratory distress syndrome. Am Rev Respir Dis 1993;147:218-33.
    • (1993) Am Rev Respir Dis , vol.147 , pp. 218-233
    • Lewis, J.F.1    Jobe, A.H.2
  • 27
    • 0032791063 scopus 로고    scopus 로고
    • Pulmonary surfactant in health and human lung diseases: State of the art
    • Griese M. Pulmonary surfactant in health and human lung diseases: state of the art. Eur Respir J 1999;13:1455-76.
    • (1999) Eur Respir J , vol.13 , pp. 1455-1476
    • Griese, M.1
  • 28
    • 0028128053 scopus 로고
    • Acute effects of a single dose of porcine surfactant on patients with the ARDS
    • Spragg RG, Gilliard N, Richman P, et al. Acute effects of a single dose of porcine surfactant on patients with the ARDS. Chest 1994;105:195-202.
    • (1994) Chest , vol.105 , pp. 195-202
    • Spragg, R.G.1    Gilliard, N.2    Richman, P.3
  • 29
    • 8244231922 scopus 로고    scopus 로고
    • Bovine surfactant therapy for patients with acute respiratory distress syndrome
    • r et al. Bovine surfactant therapy for patients with acute respiratory distress syndrome. Am J Respir Crit Care Med 1997;155:1309-15.
    • (1997) Am J Respir Crit Care Med , vol.155 , pp. 1309-1315
    • Gregory, T.J.1    Steinberg, K.P.2    Spragg, Sr.3
  • 31
    • 9344262898 scopus 로고    scopus 로고
    • Aerosolized surfactant in adults with sepsis-induced acute respiratory distress syndrome
    • Anzueto A, Baughman RP, Guntupalli K, et al. Aerosolized surfactant in adults with sepsis-induced acute respiratory distress syndrome. N Engl J Med 1996;334:1417-21.
    • (1996) N Engl J Med , vol.334 , pp. 1417-1421
    • Anzueto, A.1    Baughman, R.P.2    Guntupalli, K.3
  • 32
    • 0031750698 scopus 로고    scopus 로고
    • Aerosolized surfactant improves pulmonary function in endotoxin-induced lung injury
    • Lutz C, Carney D, Finck C, et al. Aerosolized surfactant improves pulmonary function in endotoxin-induced lung injury. Am J Respir Crit Care Med 1998;158:840-5.
    • (1998) Am J Respir Crit Care Med , vol.158 , pp. 840-845
    • Lutz, C.1    Carney, D.2    Finck, C.3
  • 33
    • 0030743504 scopus 로고    scopus 로고
    • Ultrasonic nebulization for efficient delivery of surfactant in a model of acute lung injury: Impact on gas exchange
    • Schermuly R, Schmehl T, Gunther A, Grimminger F, Seeger W, Walmrath D. Ultrasonic nebulization for efficient delivery of surfactant in a model of acute lung injury: impact on gas exchange. Am J Respir Crit Care Med 1997;156:445-53.
    • (1997) Am J Respir Crit Care Med , vol.156 , pp. 445-453
    • Schermuly, R.1    Schmehl, T.2    Gunther, A.3    Grimminger, F.4    Seeger, W.5    Walmrath, D.6
  • 35
    • 0022339259 scopus 로고
    • The effect of mucolytic and bronchodilator aerosol therapy on airway resistance in mechanically ventilated patients
    • Zandstra DF, Stoutenbeek CP, Miranda DR. The effect of mucolytic and bronchodilator aerosol therapy on airway resistance in mechanically ventilated patients. Intensive Care Med 1985;11:316-8.
    • (1985) Intensive Care Med , vol.11 , pp. 316-318
    • Zandstra, D.F.1    Stoutenbeek, C.P.2    Miranda, D.R.3
  • 36
    • 0028923447 scopus 로고
    • The effect of short term instillation of a mucolytic agent (Mesna) on airway resistance in mechanically ventilated patients
    • Fernandez R, Sole J, Blanch L, Artigas A. The effect of short term instillation of a mucolytic agent (Mesna) on airway resistance in mechanically ventilated patients. Chest 1995;107:1101-6.
    • (1995) Chest , vol.107 , pp. 1101-1106
    • Fernandez, R.1    Sole, J.2    Blanch, L.3    Artigas, A.4
  • 37
    • 0029983991 scopus 로고    scopus 로고
    • Resolution of recurrent atelectasis in spinal cord patients with administration of recombinant human DNase
    • Voelker KG, Chetty KG, Mahutte CK. Resolution of recurrent atelectasis in spinal cord patients with administration of recombinant human DNase. Intensive Care Med 1996;22:582-4.
    • (1996) Intensive Care Med , vol.22 , pp. 582-584
    • Voelker, K.G.1    Chetty, K.G.2    Mahutte, C.K.3
  • 38
    • 0033531143 scopus 로고    scopus 로고
    • Intermittent administration of inhaled tobramycin in patients with cystic fibrosis
    • Ramsey BW, Pepe MS, Quan JM, et al. Intermittent administration of inhaled tobramycin in patients with cystic fibrosis. N Engl J Med 1999;340:23-30.
    • (1999) N Engl J Med , vol.340 , pp. 23-30
    • Ramsey, B.W.1    Pepe, M.S.2    Quan, J.M.3
  • 39
    • 0016634343 scopus 로고
    • Prevention of gram-negative bacillary pneumonia using polymyxin aerosol as prophylaxis
    • Klick JM, duMoulin GC, Hedley-White J, et al. Prevention of gram-negative bacillary pneumonia using polymyxin aerosol as prophylaxis. J Clin Invest 1975;55:514-9.
    • (1975) J Clin Invest , vol.55 , pp. 514-519
    • Klick, J.M.1    DuMoulin, G.C.2    Hedley-White, J.3
  • 40
    • 0016710474 scopus 로고
    • Aerosol polymyxin and pneumonia in seriously ill patients
    • Feeley TW, duMoulin GC, Hedley-White J, et al. Aerosol polymyxin and pneumonia in seriously ill patients. N Engl J Med 1975;293:471-5.
    • (1975) N Engl J Med , vol.293 , pp. 471-475
    • Feeley, T.W.1    DuMoulin, G.C.2    Hedley-White, J.3
  • 42
    • 0030686587 scopus 로고    scopus 로고
    • Heliox in the treatment of airflow obstruction: A critical review of the literature
    • Manthous CA, Morgan S, Pohlman A, Hall JB. Heliox in the treatment of airflow obstruction: a critical review of the literature. Respir Care 1997;42:1034-42.
    • (1997) Respir Care , vol.42 , pp. 1034-1042
    • Manthous, C.A.1    Morgan, S.2    Pohlman, A.3    Hall, J.B.4
  • 45
    • 0025130061 scopus 로고
    • Helium-oxygen mixtures in intubated patients with status asthmaticus and respiratory acidosis
    • Gluck EH, Onorato DJ, Castriotta R. Helium-oxygen mixtures in intubated patients with status asthmaticus and respiratory acidosis. Chest 1990;98:693-8.
    • (1990) Chest , vol.98 , pp. 693-698
    • Gluck, E.H.1    Onorato, D.J.2    Castriotta, R.3
  • 47
    • 0032962998 scopus 로고    scopus 로고
    • The effect of heliox on nebulizer function using a β-agonist bronchodilator
    • Hess DR, Acosta FL, Ritz RH, Kacmarek RM, Camargo CA. The effect of heliox on nebulizer function using a β-agonist bronchodilator. Chest 1999;115:184-9.
    • (1999) Chest , vol.115 , pp. 184-189
    • Hess, D.R.1    Acosta, F.L.2    Ritz, R.H.3    Kacmarek, R.M.4    Camargo, C.A.5
  • 48
    • 0032913676 scopus 로고    scopus 로고
    • Effect of helium-oxygen on delivery of albuterol in a pediatric, volume cycled, ventilated lung model
    • Habib DM, Garner SS, Brandeburg S. Effect of helium-oxygen on delivery of albuterol in a pediatric, volume cycled, ventilated lung model. Pharmacotherapy 1999;19:143-9.
    • (1999) Pharmacotherapy , vol.19 , pp. 143-149
    • Habib, D.M.1    Garner, S.S.2    Brandeburg, S.3
  • 49
    • 0029757425 scopus 로고    scopus 로고
    • Clinical applications of nitric oxide
    • Mizutani T, Layon AJ. Clinical applications of nitric oxide. Chest 1996;110:506-24.
    • (1996) Chest , vol.110 , pp. 506-524
    • Mizutani, T.1    Layon, A.J.2
  • 50
    • 0031975630 scopus 로고    scopus 로고
    • Effects of inhaled nitric oxide in patients with acute respiratory distress syndrome: Results of a randomized phase II trial
    • Dellinger RP, Zimmerman JL, Taylor RW, et al. Effects of inhaled nitric oxide in patients with acute respiratory distress syndrome: results of a randomized phase II trial. Crit Care Med 1998;26:15-23.
    • (1998) Crit Care Med , vol.26 , pp. 15-23
    • Dellinger, R.P.1    Zimmerman, J.L.2    Taylor, R.W.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.