Activity of benzo[a]pyrene and its hydroxylated metabolites in an estrogen receptor-α reporter gene assay

Toxicological Sciences

Volumn 55, Issue 2, 2000, Pages 320-326

  Charles, Grantley D ^a   Bartels, Michael J ^a   Zacharewski, Timothy R ^b   Gollapudi, B Bhaskar ^a   Freshour, Nancy L ^a   Carney, Edward W ^a  

^a DOW CHEMICAL COMPANY   (United States)

^b Michigan State University   (United States)

Author keywords

napthoflavone; Benzo a pyrene; Estrogen; MCF 7 cells; Metabolite

Indexed keywords

ALPHA NAPHTHOFLAVONE; BENZO[A]PYRENE; BENZO[A]PYRENE DERIVATIVE; CYTOCHROME P450 INHIBITOR; ESTRADIOL; ESTROGEN; ESTROGEN RECEPTOR ALPHA; FULVESTRANT; HORMONE RECEPTOR BLOCKING AGENT; LUCIFERASE; POLYCYCLIC AROMATIC HYDROCARBON;

ARTICLE; BREAST CANCER; CANCER CELL; CONTROLLED STUDY; CYTOTOXICITY; ESTROGEN ACTIVITY; HUMAN; HUMAN CELL; REPORTER GENE;

BENZO(A)PYRENE; BENZOFLAVONES; BETA-GALACTOSIDASE; BREAST NEOPLASMS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DOSE-RESPONSE RELATIONSHIP, DRUG; ESTRADIOL; ESTROGEN ANTAGONISTS; ESTROGEN RECEPTOR ALPHA; FEMALE; GENE EXPRESSION; GENES, REPORTER; GENETIC TECHNIQUES; HUMANS; HYDROXYLATION; LUCIFERASES; RECEPTORS, ESTROGEN; TRANSFECTION; TUMOR CELLS, CULTURED;

MINK CELL FOCUS-FORMING VIRUS;

EID: 0034079918     PISSN: 10966080     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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