Human bronchial epithelial cells secrete laminin 5, express hemidesmosomal proteins, and assemble hemidesmosomes

Journal of Histochemistry and Cytochemistry

Volumn 48, Issue 4, 2000, Pages 535-544

  Michelson, Peter H ^a   Tigue, Margaret ^a   Jones, Jonathan C R ^a  

^a NORTHWESTERN UNIVERSITY   (United States)

Author keywords

Extracellular matrix (ECM); Hemidesmosome (HD); Integrin

Indexed keywords

ANTIGEN; INTEGRIN; KALININ; PROTEIN; STRUCTURAL PROTEIN;

ARTICLE; BRONCHUS MUCOSA; CONTROLLED STUDY; EPITHELIUM CELL; EXTRACELLULAR MATRIX; HEMIDESMOSOME; HUMAN; HUMAN CELL; IMMUNOBLOTTING; IMMUNOFLUORESCENCE MICROSCOPY; IMMUNOHISTOCHEMISTRY; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; PROTEIN EXPRESSION;

BRONCHUS;

EID: 0034076666     PISSN: 00221554     EISSN: None     Source Type: Journal    
DOI: 10.1177/002215540004800411     Document Type: Article

References (35)

1. Baker SE, DiPasquale AP, Stock EL, Quaranta V, Fitchmun M, Jones JCR (1996a) Morphogenetic effects of soluble laminin 5 on cultured epithelial cells and tissue explants. Exp Cell Res 228:262-270
2. Baker SE, Hopkinson SB, Fitchmun M, Andreason GL, Frasier F, Plopper G, Quaranta V, Jones JCR (1996b) Laminin-5 and hemidesmosomes: role of the α3 chain subunit in hemidesmosome stability and assembly. J Cell Sci 109:2509-2520
3. Borradori L, Sonnenberg A (1996) Hemidesmosomes: role in adhesion, signaling and human diseases. Curr Opin Cell Biol 8:647-656
4. Burgeson RE, Christiano AM (1997) The dermal-epidermal junction. Curr Opin Cell Biol 9:651-658
5. Craig SW, Johnson RP (1996) Assembly of focal adhesions: progress, paradigms and portents. Curr Opin Cell Biol 8:74-85
6. Dabelsteen E (1998) Molecular biological aspects of acquired bullous diseases. Crit Rev Oral Biol Med 9:162-178
7. Dunsmore SE, Rannels DE (1996) Extracellular matrix biology in the lung. Am J Physiol 270(1 pt 1):L3-27
8. Ekblom M, Falk M, Salmivirta K, Durbeej M, Ekblom P (1998) Laminin isoforms and epithelial cell development. Ann NY Acad Sci 857:194-211
9. Fuchs E, Dowling J, Segre J, Lo SH, Yu Q-C (1997) Integrators of epidermal growth and differentiation: distinct functions of β1 and β4 integrins. Curr Opin Genet Dev 7:672-682
10. Goldfinger L, Stack MS, Jones JCR (1998) Processing of laminin-5 and its functional consequences: role of plasmin and tissue-type plasminogen activator. J Cell Biol 141:255-265
11. Gonzales M, Haan K, Baker SE, Fitchmun M, Todorov I, Weitzman S, Jones JCR (1999) A cell signal pathway involving laminin-5, α3β1 integrin and MAP kinase can regulate epithelial cell proliferation. Mol Biol Cell 10:259-270
12. Gospodarowicz D (1984) Preparation of extracellular matrices produced by cultured bovine corneal endothelial cells and PF-HR-9 endodermal cells: their use in cell culture. In Sirbasku DA, Stao GH, Barnes DW, eds. Methods of Preparation of Media Supplements and Substrata. Vol 1. New York, Alan R Liss, 275-293
13. Green KJ, Jones JCR (1996) Desmosomes and hemidesmosomes: structure and function of molecular components. FASEB J 10:871-881
14. Hashimoto T, Amagai M, Ebihara T, Gamou S, Shimizu N, Tsubata T, Hasegawa A, Miki K, Nishikawa T (1993) Further analyses of epitopes for human monoclonal anti-basement membrane zone antibodies produced by stable human hybridoma cell lines constructed with Epstein-Barr virus transformants. J Invest Dermatol 100:310-315
15. Hopkinson SB, Riddelle KS, Jones JCR (1992) Cytoplasmic domain of the 180-kD bullous pemphigoid antigen, a hemidesmosomal component: molecular and cell biologic characterization. J Invest Dermatol 99:264-270
16. Howe A, Aplin AE, Alahari SK, Juliano RL (1998) Integrin signaling and cell growth control. Curr Opin Cell Biol 10:220-231
17. Hynes RO (1992) Integrins: versatility, modulation and signaling in cell adhesion. Cell 69:11-25
18. Jones JCR, Asmuth J, Baker SE, Langhofer M, Roth SI, Hopkinson SB (1994) Hemidesmosomes: extracellular matrix/intermediate filament connectors. Exp Cell Res 213:1-11
19. Jones JCR, Hopkinson SB, Goldfinger LE (1998) Structure and assembly of hemidesmosomes. Bioessays 20:488-494
20. Khavari PA (1998) Gene therapy for genetic skin disease. J Invest Dermatol 110:462-467
21. Koukoulis GK, Warren WH, Virtanen I, Gould VE (1997) Immunolocalization of integrins in the normal lung and in pulmonary carcinomas. Hum Pathol 28:1018-1025
22. 4. Nature 227:680-685
23. Mainiero F, Pepe A, Wary KK, Spinardi L, Mohammadi M, Schlessinger J, Giancotti FG (1995) Signal transduction by the α6β4 integrin: distinct β4 subunit sites mediate recruitment of Shc/Grb2 and association with the cytoskeleton of hemidesmosomes. EMBO J 14:4470-4481
24. Mainiero F, Pepe A, Yeon M, Ren Y, Giancotti FG (1996) The intracellular functions of α6β4 integrin are regulated by EGF. J Cell Biol 134:241-253
25. Marinkovich MP, Lunstrum GP, Burgeson RE (1992) The anchoring filament protein kalinin is synthesized and secreted as a high molecular weight precursor. J Biol Chem 267:17900-17906
26. Pilewski JM, Albelda SM (1993) Adhesion molecules in the lung. An overview. Am Rev Respir Dis 148:S31-37
27. Rahinovitz I, Mercurio AM (1996) The integrin α64 and the biology of carcinoma. Biochem Cell Biol 74:811-821
28. Riddelle KS, Green KJ, Jones JCR (1991) Formation of hemidesmosomes in vitro by a rat bladder cell line. J Cell Biol 112: 159-168
29. Roche WR (1998) The inflammatory and structural changes in the small airways in bronchial asthma. Am J Respir Crit Care Med 157:S191-194
30. Schaapveld RQJ, Boradori L, Geerts D, van Leusden MR, Kuikman I, Nievers MG, Niessen CM, Steenbergen RDM, Snijders RJF, Sonnenberg A (1998) Hemidesmosome formation is initiated by the integrin β4 and HD1/plectin, and involves a direct interaction between β4 and the bullous pemphigoid antigen 180. J Cell Biol 142:271-284
31. Schuger L (1997) Laminins in lung development. Exp Lung Res 23:119-129
32. Shaw DW, Fine J, Piacquadio DJ, Greenherg MJ, Wang-Rodriguez J, Eichenwald LF (1997) Gastric outlet obstruction and epidermolysis bullosa. J Am Acad Dermatol 36:304-310
33. Stahl S, Weitzman S, Jones JCR (1997) The role of laminin-5 and its receptors in mammary epithelial cell branching morphogenesis. J Cell Sci 110:55-63
34. Uematsu J, Nishizawa Y, Sonnenberg A, Owaribe K (1994) Demonstration of type II hemidesmosomes in a mammary gland epithelial cell line, BMGE-H. J Biochem 115:469-476
35. Virtanen I, Laitinen A, Tani T, Paakko P, Laitinen L, Burgeson RE, Lehto V-P (1996) Differential expression of laminins and their integrin receptors in developing and adult human lung. Am J Respir Cell Mol Biol 15:184-196