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Volumn 57, Issue 4, 2000, Pages 604-611

Ras-related and MAPK signalling in neuronal plasticity and memory formation

Author keywords

Hippocampus; Learning and memory; Ras MAPK signalling; Synaptic plasticity

Indexed keywords

MITOGEN ACTIVATED PROTEIN KINASE; RAS PROTEIN;

EID: 0034071898     PISSN: 1420682X     EISSN: None     Source Type: Journal    
DOI: 10.1007/PL00000722     Document Type: Review
Times cited : (147)

References (57)
  • 1
    • 0030272962 scopus 로고    scopus 로고
    • Cell adhesion molecules, CREB, and the formation of new synaptic connections
    • 1 Martin K. C. and Kandel E. R. (1996) Cell adhesion molecules, CREB, and the formation of new synaptic connections. Neuron 17: 567-570
    • (1996) Neuron , vol.17 , pp. 567-570
    • Martin, K.C.1    Kandel, E.R.2
  • 2
    • 0032032006 scopus 로고    scopus 로고
    • Cognitive neuroscience and the study of memory
    • 2 Milner B., Squire L. R. and Kandel E. R. (1998) Cognitive neuroscience and the study of memory. Neuron 20: 445-468
    • (1998) Neuron , vol.20 , pp. 445-468
    • Milner, B.1    Squire, L.R.2    Kandel, E.R.3
  • 3
    • 0030450763 scopus 로고    scopus 로고
    • Toward a molecular definition of long-term memory storage
    • 3 Bailey C. H., Bartsch D. and Kandel E. R. (1996) Toward a molecular definition of long-term memory storage. Proc. Natl. Acad. Sci. USA 93: 13445-13452
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 13445-13452
    • Bailey, C.H.1    Bartsch, D.2    Kandel, E.R.3
  • 4
    • 0030057530 scopus 로고    scopus 로고
    • Long-term potentiation and learning
    • 4 Martinez J. L. and Derrick B. E. (1996) Long-term potentiation and learning. Annu. Rev. Psychol. 47: 173-203
    • (1996) Annu. Rev. Psychol. , vol.47 , pp. 173-203
    • Martinez, J.L.1    Derrick, B.E.2
  • 5
    • 0031055834 scopus 로고    scopus 로고
    • Molecular genetic analysis of synaptic plasticity, activity-dependent neural development, learning and memory in the mammalian brain
    • 5 Chen C. and Tonegawa S. (1997) Molecular genetic analysis of synaptic plasticity, activity-dependent neural development, learning and memory in the mammalian brain. Annu. Rev. Neurosci. 20: 157-184
    • (1997) Annu. Rev. Neurosci. , vol.20 , pp. 157-184
    • Chen, C.1    Tonegawa, S.2
  • 6
    • 0029670941 scopus 로고    scopus 로고
    • 2 + - dependent routes to Ras: Mechanisms for neuronal survival, differentiation and plasticity?
    • 2 + - dependent routes to Ras: mechanisms for neuronal survival, differentiation and plasticity? Neuron 16: 233-236
    • (1996) Neuron , vol.16 , pp. 233-236
    • Finkbeiner, S.1    Greenberg, M.E.2
  • 7
    • 0242722234 scopus 로고    scopus 로고
    • Is the Ras/MAPK signalling pathway necessary for long-term memory formation?
    • 7 Orban P. C., Chapman P. F. and Brambilla R. (1999) Is the Ras/MAPK signalling pathway necessary for long-term memory formation? Trends Neurosci. 22: 38-44
    • (1999) Trends Neurosci. , vol.22 , pp. 38-44
    • Orban, P.C.1    Chapman, P.F.2    Brambilla, R.3
  • 8
    • 0033136259 scopus 로고    scopus 로고
    • Making new connections: Role of ERK/MAP kinase signaling in neuronal plasticity
    • 8 Impey S., Obrietan K. and Storm D. R. (1999) Making new connections: role of ERK/MAP kinase signaling in neuronal plasticity. Neuron 23: 11-14
    • (1999) Neuron , vol.23 , pp. 11-14
    • Impey, S.1    Obrietan, K.2    Storm, D.R.3
  • 9
    • 0032861127 scopus 로고    scopus 로고
    • Extracellular-signal-regulated kinase signalling in neurons
    • 9 Grewal S. S., York R. D. and Stork P. J. (1999) Extracellular-signal-regulated kinase signalling in neurons. Curr. Opin. Neurobiol. 9: 544-553
    • (1999) Curr. Opin. Neurobiol. , vol.9 , pp. 544-553
    • Grewal, S.S.1    York, R.D.2    Stork, P.J.3
  • 11
    • 0032103332 scopus 로고    scopus 로고
    • Ets transcription factors: Nuclear effectors of the Ras-MAP-kinase signaling pathway
    • 11 Wasylyk B., Hagman J. and Gutierrez-Hartmann A. (1998) Ets transcription factors: nuclear effectors of the Ras-MAP-kinase signaling pathway. Trends Biochem. Sci. 23: 213-216
    • (1998) Trends Biochem. Sci. , vol.23 , pp. 213-216
    • Wasylyk, B.1    Hagman, J.2    Gutierrez-Hartmann, A.3
  • 12
    • 0027215902 scopus 로고
    • Regulation of gene expression in hippocampal neurons by distinct calcium signaling pathways
    • 12 Bading H., Ginty D. D. and Greenberg M. E. (1993) Regulation of gene expression in hippocampal neurons by distinct calcium signaling pathways. Science 260: 181-186
    • (1993) Science , vol.260 , pp. 181-186
    • Bading, H.1    Ginty, D.D.A.2    Greenberg, M.E.3
  • 13
    • 0028277844 scopus 로고
    • Membrane depolarization and calcium influx stimulate MEK and MAP kinase via activation of Ras
    • 13 Rosen, L. B., Ginty, D. D., Weber, M. J. and Greenberg, M. E. (1994) Membrane depolarization and calcium influx stimulate MEK and MAP kinase via activation of Ras. Neuron 12:
    • (1994) Neuron , vol.12
    • Rosen, L.B.1    Ginty, D.D.2    Weber, M.J.3    Greenberg, M.E.4
  • 14
    • 0028987937 scopus 로고
    • Calcium signaling in neurons: Molecular mechanisms and cellular consequences
    • 14 Ghosh, A. and Greenberg N. M. E. (1995) Calcium signaling in neurons: molecular mechanisms and cellular consequences. Science 268: 239-247
    • (1995) Science , vol.268 , pp. 239-247
    • Ghosh, A.1    Greenberg, N.M.E.2
  • 15
    • 0345579566 scopus 로고    scopus 로고
    • Activation of p42 mitogen-activated protein kinase in hippocampal long term potentiation
    • 15 English J. D. and Sweatt J. D. (1996) Activation of p42 mitogen-activated protein kinase in hippocampal long term potentiation. J. Biol. Chem. 271: 24329-24332
    • (1996) J. Biol. Chem. , vol.271 , pp. 24329-24332
    • English, J.D.1    Sweatt, J.D.2
  • 16
    • 0030908089 scopus 로고    scopus 로고
    • MAP kinase translocates into the nucleus of the presynaptic cell and his required for long-term facilitation in Aplysia
    • 16 Martin K. C., Michael D., Rose J. C., Barad M., Casadio A., Zhu H. et al. (1997) MAP kinase translocates into the nucleus of the presynaptic cell and his required for long-term facilitation in Aplysia. Neuron 18: 899-912
    • (1997) Neuron , vol.18 , pp. 899-912
    • Martin, K.C.1    Michael, D.2    Rose, J.C.3    Barad, M.4    Casadio, A.5    Zhu, H.6
  • 17
    • 0030920771 scopus 로고    scopus 로고
    • A kinase to remember: Dual roles for MAP kinase in long-term memory
    • 17 Kornhauser J. M. and Greenberg M. E. (1997) A kinase to remember: dual roles for MAP kinase in long-term memory. Neuron 18: 839-842
    • (1997) Neuron , vol.18 , pp. 839-842
    • Kornhauser, J.M.1    Greenberg, M.E.2
  • 18
    • 0032539621 scopus 로고    scopus 로고
    • Repeated pulses of serotonin required for long-term facilitation activate mitogen-activated protein kinase in sensory neurons of Aplysia
    • 18 Michael D., Martin K. C., Seger R., Ning M. M., Baston R. and Kandel E. R. (1998) Repeated pulses of serotonin required for long-term facilitation activate mitogen-activated protein kinase in sensory neurons of Aplysia. Proc Natl Acad Sci U S A 95: 1864-1869
    • (1998) Proc Natl Acad Sci U S A , vol.95 , pp. 1864-1869
    • Michael, D.1    Martin, K.C.2    Seger, R.3    Ning, M.M.4    Baston, R.5    Kandel, E.R.6
  • 19
    • 0030887633 scopus 로고    scopus 로고
    • Ubiquitin C-terminal hydrolase is an immediate-early gene essential for long-term facilitation in Aplysia
    • 19 Hegde A. N., Inokuchi K., Pei W., Casadio A., Ghirardi M., Chain D. G. et al. (1997) Ubiquitin C-terminal hydrolase is an immediate-early gene essential for long-term facilitation in Aplysia. Cell 89: 115-126
    • (1997) Cell , vol.89 , pp. 115-126
    • Hegde, A.N.1    Inokuchi, K.2    Pei, W.3    Casadio, A.4    Ghirardi, M.5    Chain, D.G.6
  • 20
    • 0030920583 scopus 로고    scopus 로고
    • Mutation in the phosphorylation sites of MAP kinase blocks learning-related internalization of apCAM in Aplysia sensory neurons
    • 20 Bailey C. H., Kaang B.-K., Chen M., Martin K. C., Lim C.-S., Casadio A. et al. (1997) Mutation in the phosphorylation sites of MAP kinase blocks learning-related internalization of apCAM in Aplysia sensory neurons. Neuron 18: 913-924
    • (1997) Neuron , vol.18 , pp. 913-924
    • Bailey, C.H.1    Kaang, B.-K.2    Chen, M.3    Martin, K.C.4    Lim, C.-S.5    Casadio, A.6
  • 21
    • 0032080250 scopus 로고    scopus 로고
    • Phosphorylation of mitogen-activated protein kinase by one-trial and multi-trial classical conditioning
    • 21 Crow T. et al. (1998) Phosphorylation of mitogen-activated protein kinase by one-trial and multi-trial classical conditioning. J. Neurosci. 18: 3480-3487
    • (1998) J. Neurosci. , vol.18 , pp. 3480-3487
    • Crow, T.1
  • 22
    • 0029790007 scopus 로고    scopus 로고
    • A biochemist's view of long-term potentiation
    • 22 Roberson E. D., English J. D. and Sweatt J. D. (1996) A biochemist's view of long-term potentiation. Learn. Mem. 3: 1-24
    • (1996) Learn. Mem. , vol.3 , pp. 1-24
    • Roberson, E.D.1    English, J.D.2    Sweatt, J.D.3
  • 23
    • 0030749510 scopus 로고    scopus 로고
    • A requirement for the mitogen-activated protein kinase cascade in hippocampal long-term potentiation
    • 23 English J. D. and Sweatt J. D. (1997) A requirement for the mitogen-activated protein kinase cascade in hippocampal long-term potentiation. J. Biol. Chem. 272: 19103-19106
    • (1997) J. Biol. Chem. , vol.272 , pp. 19103-19106
    • English, J.D.1    Sweatt, J.D.2
  • 24
    • 0033230165 scopus 로고    scopus 로고
    • ERK plays a regulatory role in induction of LTP by theta frequency stimulation and its modulation by β-adrenergic receptors
    • 24 Winder D. G. and Kandel E. R. (1999) ERK plays a regulatory role in induction of LTP by theta frequency stimulation and its modulation by β-adrenergic receptors. Neuron 24: 715-726
    • (1999) Neuron , vol.24 , pp. 715-726
    • Winder, D.G.1    Kandel, E.R.2
  • 25
    • 0033136259 scopus 로고    scopus 로고
    • Making new connections: Role of ERK/MAP kinase signaling in neuronal plasticity
    • 25 Impey S., Obrietan K. and Storm D. R. (1999) Making new connections: role of ERK/MAP kinase signaling in neuronal plasticity. Neuron 23: 11-14
    • (1999) Neuron , vol.23 , pp. 11-14
    • Impey, S.1    Obrietan, K.2    Storm, D.R.3
  • 26
    • 0033152333 scopus 로고    scopus 로고
    • The mitogen-activated protein kinase cascade couples PKA and PKC to cAMP response clement binding protein phosphorylation in area CA1 of hippocampus
    • 26 Roberson E.D. et al. (1999) The mitogen-activated protein kinase cascade couples PKA and PKC to cAMP response clement binding protein phosphorylation in area CA1 of hippocampus. J. Neurosci. 19: 4337-4348
    • (1999) J. Neurosci. , vol.19 , pp. 4337-4348
    • Roberson, E.D.1
  • 27
    • 0032401757 scopus 로고    scopus 로고
    • All in the family? New insights and questions regarding interconnectivity of Ras, Rap1 and Ra1
    • 27 Bos J. L. (1998) All in the family? New insights and questions regarding interconnectivity of Ras, Rap1 and Ra1. EMBO J. 17: 6776-6782
    • (1998) EMBO J. , vol.17 , pp. 6776-6782
    • Bos, J.L.1
  • 28
    • 0028113461 scopus 로고
    • Activation and tyrosine phosphorylation of 44-kDa mitogen-activated protein kinase (MAPK) induced by electroconvulsive shock in rat hippocampus
    • 28 Kang U. G., Hong K. S., Jung H. Y., Kim Y. S., Seong Y. S., Yang Y. C. et al. (1994) Activation and tyrosine phosphorylation of 44-kDa mitogen-activated protein kinase (MAPK) induced by electroconvulsive shock in rat hippocampus. J. Neurochem. 63: 1979-1982
    • (1994) J. Neurochem. , vol.63 , pp. 1979-1982
    • Kang, U.G.1    Hong, K.S.2    Jung, H.Y.3    Kim, Y.S.4    Seong, Y.S.5    Yang, Y.C.6
  • 29
    • 0030020261 scopus 로고    scopus 로고
    • Potassium chloride pulse enhances mitogen-activated protein kinase activity in rat hippocampal slices
    • 29 Baron C., Benes C., Van Tan H., Fagard R. and Roisin M. P. (1996) Potassium chloride pulse enhances mitogen-activated protein kinase activity in rat hippocampal slices. J. Neurochem. 66: 1005-1010
    • (1996) J. Neurochem. , vol.66 , pp. 1005-1010
    • Baron, C.1    Benes, C.2    Van Tan, H.3    Fagard, R.4    Roisin, M.P.5
  • 30
    • 0033028138 scopus 로고    scopus 로고
    • P42/44 MAP kinase inhibitor PD98059 attenuates multiple forms of synaptic plasticity in rat dentate gyrus in vitro
    • 30 Coogan A. N., O'Leary D. M. and O'Connor J. J. (1999) P42/44 MAP kinase inhibitor PD98059 attenuates multiple forms of synaptic plasticity in rat dentate gyrus in vitro. J. Neurophysiol. 81: 103-110
    • (1999) J. Neurophysiol. , vol.81 , pp. 103-110
    • Coogan, A.N.1    O'Leary, D.M.2    O'Connor, J.J.3
  • 31
    • 0032213310 scopus 로고    scopus 로고
    • Extracellular signal-regulated kinase (ERK) controls immediate early gene induction on corticostriatal stimulation
    • 31 Sgambato V. et al. (1998) Extracellular signal-regulated kinase (ERK) controls immediate early gene induction on corticostriatal stimulation. J. Neurosci. 18: 8814-8825
    • (1998) J. Neurosci. , vol.18 , pp. 8814-8825
    • Sgambato, V.1
  • 32
    • 0032947179 scopus 로고    scopus 로고
    • Glutamate induces phosphorylation of Elk-1 and CREB, along with c-fos activation, via an extracellular signal-regulated kinase-dependent pathway in brain slices
    • 32 Vanhoutte P., Barnier J. V., Guibert B., Pages C., Besson M. J., Hipskind R. A. et al. (1999) Glutamate induces phosphorylation of Elk-1 and CREB, along with c-fos activation, via an extracellular signal-regulated kinase-dependent pathway in brain slices. Mol. Cell. Biol. 19: 136-146
    • (1999) Mol. Cell. Biol. , vol.19 , pp. 136-146
    • Vanhoutte, P.1    Barnier, J.V.2    Guibert, B.3    Pages, C.4    Besson, M.J.5    Hipskind, R.A.6
  • 33
    • 0033532060 scopus 로고    scopus 로고
    • Requirement for mitogen-activated protein kinase in cerebellar long term depression
    • 33 Kawasaki H. et al. (1999) Requirement for mitogen-activated protein kinase in cerebellar long term depression. J. Biol. Chem. 274: 13498-13502
    • (1999) J. Biol. Chem. , vol.274 , pp. 13498-13502
    • Kawasaki, H.1
  • 35
    • 0032725305 scopus 로고    scopus 로고
    • A necessity for MAP kinase activation in mammalian spatial learning
    • 35 Selcher J. C., Atkins C. M., Trzaskos J. M., Paylor R. and Sweatt J. D. (1999) A necessity for MAP kinase activation in mammalian spatial learning [In Process Citation]. Learn. Mem. 6: 478-490
    • (1999) Learn. Mem. , vol.6 , pp. 478-490
    • Selcher, J.C.1    Atkins, C.M.2    Trzaskos, J.M.3    Paylor, R.4    Sweatt, J.D.5
  • 36
    • 0032944350 scopus 로고    scopus 로고
    • Memory consolidation for contextual and auditory fear conditioning is dependent on protein synthesis, PKA and MAP kinase
    • 36 Schafe G. E. et al. (1999) Memory consolidation for contextual and auditory fear conditioning is dependent on protein synthesis, PKA and MAP kinase. Learn. Mem. 6: 97-110
    • (1999) Learn. Mem. , vol.6 , pp. 97-110
    • Schafe, G.E.1
  • 37
    • 0032402195 scopus 로고    scopus 로고
    • Specific and differential activation of mitogen-activated protein kinase cascades by unfamiliar taste in the insular cortex of the behaving rat
    • 37 Berman D. E., Hazvi S., Rosenblum K., Seger R. and Dudai Y. (1998) Specific and differential activation of mitogen-activated protein kinase cascades by unfamiliar taste in the insular cortex of the behaving rat. J. Neurosci. 18: 10037-10044
    • (1998) J. Neurosci. , vol.18 , pp. 10037-10044
    • Berman, D.E.1    Hazvi, S.2    Rosenblum, K.3    Seger, R.4    Dudai, Y.5
  • 38
    • 0033135345 scopus 로고    scopus 로고
    • A mitogen-activated protein kinase cascade in the CA1/CA2 subfield of the dorsal hippocampus is essential for long-term spatial memory
    • 38 Blum S., Moore A. N., Adams F. and Dash P. K. (1999) A mitogen-activated protein kinase cascade in the CA1/CA2 subfield of the dorsal hippocampus is essential for long-term spatial memory. J. Neurosci. 19: 3535-3544
    • (1999) J. Neurosci. , vol.19 , pp. 3535-3544
    • Blum, S.1    Moore, A.N.2    Adams, F.3    Dash, P.K.4
  • 39
    • 0032887114 scopus 로고    scopus 로고
    • Dose-dependent impairment of inhibitory avoidance retention in rats by immediate post-training infusion of a mitogen-activated protein kinase kinase inhibitor into cortical structures
    • 39 Walz R., Roesler R., Quevedo J., Rockenbach I. C., Amaral O. B., Vianna M. R. et al. (1999) Dose-dependent impairment of inhibitory avoidance retention in rats by immediate post-training infusion of a mitogen-activated protein kinase kinase inhibitor into cortical structures [In Process Citation]. Behav. Brain. Res. 105: 219-223
    • (1999) Behav. Brain. Res. , vol.105 , pp. 219-223
    • Walz, R.1    Roesler, R.2    Quevedo, J.3    Rockenbach, I.C.4    Amaral, O.B.5    Vianna, M.R.6
  • 41
    • 0026590055 scopus 로고
    • Recent progress toward understanding the molecular biology of von Recklinghausen neurofibromatosis
    • 41 Gutmann D. H. and Collins F. S. (1992) Recent progress toward understanding the molecular biology of von Recklinghausen neurofibromatosis. Ann. Neurol. 31: 555-561
    • (1992) Ann. Neurol. , vol.31 , pp. 555-561
    • Gutmann, D.H.1    Collins, F.S.2
  • 42
    • 0027202164 scopus 로고
    • Molecular biology of the neurofibromatoses
    • 42 Riccardi V. M. (1993) Molecular biology of the neurofibromatoses. Semin. Dermatol. 12: 266-273
    • (1993) Semin. Dermatol. , vol.12 , pp. 266-273
    • Riccardi, V.M.1
  • 43
    • 0028231155 scopus 로고
    • New insights into the neurofibromatoses
    • 43 Gutmann D. H. (1994) New insights into the neurofibromatoses. Curr. Opin. Neurol. 7: 166-171
    • (1994) Curr. Opin. Neurol. , vol.7 , pp. 166-171
    • Gutmann, D.H.1
  • 44
    • 0028046039 scopus 로고
    • Neurofibromatosis and related tumors. Natural occurrence and animal models
    • 44 Riccardi V. M., Womack J. E. and Jacks T. (1994) Neurofibromatosis and related tumors. Natural occurrence and animal models. Am. J. Pathol. 145: 994-1000
    • (1994) Am. J. Pathol. , vol.145 , pp. 994-1000
    • Riccardi, V.M.1    Womack, J.E.2    Jacks, T.3
  • 45
    • 0022982377 scopus 로고
    • Neurofibromatosis: Implications for learning and behavior
    • 45 Eliason M. J. (1986) Neurofibromatosis: implications for learning and behavior. J. Dev. Behav. Pediatr. 7: 175-179
    • (1986) J. Dev. Behav. Pediatr. , vol.7 , pp. 175-179
    • Eliason, M.J.1
  • 46
    • 0023916416 scopus 로고
    • Neuropsychological patterns: Neurofibromatosis compared to developmental learning disorders
    • 46 Eliason M. J. (1988) Neuropsychological patterns: neurofibromatosis compared to developmental learning disorders. Neurofibromatosis 1: 17-25
    • (1988) Neurofibromatosis , vol.1 , pp. 17-25
    • Eliason, M.J.1
  • 47
    • 0028847343 scopus 로고
    • Neuropsychological function and MRI abnormalities in neurofibromatosis type I
    • 47 Joy P., Roberts C., North K. and de Silva M. (1995) Neuropsychological function and MRI abnormalities in neurofibromatosis type I. Dev. Med. Child Neurol. 37: 906-914
    • (1995) Dev. Med. Child Neurol. , vol.37 , pp. 906-914
    • Joy, P.1    Roberts, C.2    North, K.3    De Silva, M.4
  • 48
    • 0028307561 scopus 로고
    • Specific learning disability in children with neurofibromatosis type I: Significance of MRI abnormalities
    • 48 North K., Joy P., Yuille D., Cocks N., Mobbs E., Hutchins P. el al. (1994) Specific learning disability in children with neurofibromatosis type I: significance of MRI abnormalities [see comments]. Neurology 44: 878-883
    • (1994) Neurology , vol.44 , pp. 878-883
    • North, K.1    Joy, P.2    Yuille, D.3    Cocks, N.4    Mobbs, E.5    Hutchins, P.6
  • 49
    • 0029035129 scopus 로고
    • Cognitive function and academic performance in children with neurofibromatosis type I
    • 49 North K., Joy P., Yuille D., Cocks N. and Hutchins P. (1995) Cognitive function and academic performance in children with neurofibromatosis type I. Dev. Med. Child Neurol. 37: 427-436
    • (1995) Dev. Med. Child Neurol. , vol.37 , pp. 427-436
    • North, K.1    Joy, P.2    Yuille, D.3    Cocks, N.4    Hutchins, P.5
  • 51
    • 0028349997 scopus 로고
    • Targeted disruption of the neurofibromatosis type-1 leads to developmental abnormalities in heart and various neural crest-derived tissues
    • 51 Brannan C. I., Perkins A. S., Vogel K. S., Ratner N., Nordlund M. L., Reid S. W. et al. (1994) Targeted disruption of the neurofibromatosis type-1 leads to developmental abnormalities in heart and various neural crest-derived tissues. Genes Dev. 8: 1019-1029
    • (1994) Genes Dev. , vol.8 , pp. 1019-1029
    • Brannan, C.I.1    Perkins, A.S.2    Vogel, K.S.3    Ratner, N.4    Nordlund, M.L.5    Reid, S.W.6
  • 52
    • 0031018226 scopus 로고    scopus 로고
    • A mouse model for the learning and memory deficits associated with neurofibromatosis type I
    • 52 Silva A. J., Frankland P. W., Marowitz Z., Friedman E., Lazlo G., Cioffi D. et al. (1997) A mouse model for the learning and memory deficits associated with neurofibromatosis type I. Nature Genet. 15: 281-284
    • (1997) Nature Genet. , vol.15 , pp. 281-284
    • Silva, A.J.1    Frankland, P.W.2    Marowitz, Z.3    Friedman, E.4    Lazlo, G.5    Cioffi, D.6
  • 53
    • 0031581209 scopus 로고    scopus 로고
    • A role for the Ras signalling pathway in synaptic transmission and long-term memory
    • 53 Brambilla R., Gnesutta N., Minichiello L., White G., Roylance A. J., Herron C. E. et al. (1997) A role for the Ras signalling pathway in synaptic transmission and long-term memory. Nature 390: 281-286
    • (1997) Nature , vol.390 , pp. 281-286
    • Brambilla, R.1    Gnesutta, N.2    Minichiello, L.3    White, G.4    Roylance, A.J.5    Herron, C.E.6
  • 54
    • 0030580974 scopus 로고    scopus 로고
    • How many X-linked genes for non-specific mental retardation (MRX) are there?
    • 54 Gedeon A. K., Donnelly A. J., Mulley J. C., Kerr B. and Turner G. (1996) How many X-linked genes for non-specific mental retardation (MRX) are there? [letter]. Am. J. Med. Genet. 64: 158-162
    • (1996) Am. J. Med. Genet. , vol.64 , pp. 158-162
    • Gedeon, A.K.1    Donnelly, A.J.2    Mulley, J.C.3    Kerr, B.4    Turner, G.5
  • 55
    • 0029832136 scopus 로고    scopus 로고
    • Mutations in the kinase Rsk-2 associated with Coffin-Lowry syndrome
    • 55 Trivier E., De Cesare D., Jacquot S., Pannetier S., Zackai E., Young I. et al. (1996) Mutations in the kinase Rsk-2 associated with Coffin-Lowry syndrome. Nature 384: 567-570
    • (1996) Nature , vol.384 , pp. 567-570
    • Trivier, E.1    De Cesare, D.2    Jacquot, S.3    Pannetier, S.4    Zackai, E.5    Young, I.6
  • 56
    • 0031710557 scopus 로고    scopus 로고
    • PAK3 mutation in nonsyndromic X-linked mental retardation
    • 56 Allen K.M. et al. (1998) PAK3 mutation in nonsyndromic X-linked mental retardation. Nature Genet. 20: 25-30
    • (1998) Nature Genet. , vol.20 , pp. 25-30
    • Allen, K.M.1
  • 57
    • 0032910443 scopus 로고    scopus 로고
    • A missense mutation in RPS6KA3 (RSK2) responsible for non-specific mental retardation
    • 57 Merienne K., Jacquot S., Pannetier S., Zeniou M., Bankier A., Gecz J. et al. (1999) A missense mutation in RPS6KA3 (RSK2) responsible for non-specific mental retardation [letter]. Nature Genet. 22: 13-14
    • (1999) Nature Genet. , vol.22 , pp. 13-14
    • Merienne, K.1    Jacquot, S.2    Pannetier, S.3    Zeniou, M.4    Bankier, A.5    Gecz, J.6


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