The pattern of prion-related protein expression in the gastrointestinal tract

Virchows Archiv

Volumn 436, Issue 5, 2000, Pages 466-472

  Pammer, J ^a   Cross, H S ^a   Frobert, Y ^b   Tschachler, E ^a   Oberhuber, G ^a  

^a UNIVERSITY OF VIENNA   (Austria)

^b CEA SACLAY   (France)

Author keywords

Epithelia; Gastrointestinal mucosa; Inflammation; Prion protein

Indexed keywords

PRION PROTEIN;

ARTICLE; BRAIN SPONGIOSIS; CRYPT CELL; DIGESTIVE SYSTEM INFLAMMATION; DISEASE TRANSMISSION; DOWN REGULATION; EPITHELIUM; GASTRITIS; GASTROINTESTINAL DISEASE; GASTROINTESTINAL MUCOSA; GASTROINTESTINAL TRACT; HELICOBACTER PYLORI; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOCHEMISTRY; LARGE INTESTINE DISEASE; PATHOPHYSIOLOGY; PRION DISEASE; PRIORITY JOURNAL; PROTEIN EXPRESSION; RECEPTOR UPREGULATION; SMALL INTESTINE DISEASE;

DIGESTIVE SYSTEM; EPITHELIUM; ESOPHAGUS; GASTRIC MUCOSA; GASTRITIS; HELICOBACTER INFECTIONS; HELICOBACTER PYLORI; HUMANS; IMMUNOENZYME TECHNIQUES; INTESTINAL MUCOSA; PRPC PROTEINS; RETROSPECTIVE STUDIES; TUMOR CELLS, CULTURED; UP-REGULATION;

EID: 0034068259     PISSN: 09456317     EISSN: None     Source Type: Journal    
DOI: 10.1007/s004280050474     Document Type: Article

References (33)

1. 1. Anderson RM, Donnelly CA, Ferguson NM, Woolhouse ME, Watt CJ, Udy HJ, MaWhinney S, Dunstan SP, Southwood TR, Wilesmith JW, Ryan JB, Hoinville LJ, Hillerton JE, Austin AR, Wells GA (1996) Transmission dynamics and epidemiology of BSE in British cattle. Nature 382:779-788
2. 2. Beaulieu JF, Quaroni A (1991) Clonal analysis of sucrase-isomaltase expression in the human colon adenocarcinoma Caco-2 cells. Biochem J 280:599-608
3. 3. Beekes M, Baldauf E, Diringer H (1996) Sequential appearance and accumulation of pathognomonic markers in the central nervous system of hamsters orally infected with scrapie. J Gen Virol 77:1925-1934
4. 4. Bendheim PE, Brown HR, Rudelli RD, Scala LJ, Goller NL, Wen GY, Kascsak RJ, Cashman NR, Bolton DC (1992) Nearly ubiquitous tissue distribution of the scrapie agent precursor protein. Neurology 42:149-156
5. 5. Bons N, Mestre Frances N, Guiraud I, Charnay Y (1997) Prion immunoreactivity in brain, tonsil, gastrointestinal epithelial cells, and blood and lymph vessels in lemurian zoo primates with spongiform encephalopathy. C R Acad Sci III 320:971-979
6. 6. Bons N, Mestre-Frances N, Belli P, Cathala F, Gajdusek DC, Brown P (1999) Natural and experimental oral infection of nonhuman primates by bovine spongiform encephalopathy agents. Proc Natl Acad Sci U S A 96:4046-4051
7. 7. Borchelt DR, Scott M, Taraboulos A, Stahl N, Prusiner SB (1990) Scrapie and cellular prion proteins differ in their kinetics of synthesis and topology in cultured cells. J Cell Biol 110:743-752
8. 8. Brandner S, Raeber A, Sailer A, Blattler T, Fischer M, Weissmann C, Aguzzi A (1996) Normal host prion protein (PrPC) is required for scrapie spread within the central nervous system. Proc Natl Acad Sci U S A 93:13148-13151
9. 9. Bruce ME, Will RG, Ironside JW, McConnell I, Drummond D, Suttie A, McCardle L, Chree A, Hope J, Birkett C, Cousens S, Fraser H, Bostock CJ (1997) Transmissions to mice indicate that 'new variant' CJD is caused by the BSE agent. Nature 389:498-501
10. 10. Cashman NR, Loertscher R, Nalbantoglu J, Shaw I, Kascsak RJ, Bolton DC, Bendheim PE (1990) Cellular isoform of the scrapie agent protein participates in lymphocyte activation. Cell 61:185-192
11. 11. Foster JD, Hope J, Fraser H (1993) Transmission of bovine spongiform encephalopathy to sheep and goats. Vet Rec 133:339-341
12. 12. Fournier J, Escaig Haye F, Billette de Villemeur T, Robain O, Lasmezas CI, Deslys JP, Dormont D, Brown P (1998) Distribution and submicroscopic immunogold localization of cellular prion protein (PrPc) in extracerebral tissues. Cell Tissue Res 292:77-84
13. 13. Gajdusek CD (1996) Infectious amyloids. In: Fields BN, Knipe DM, Howley PM (eds) Fields virology. Lippincott-Raven, Philadelphia, pp 2851-2900
14. 14. Gibbs CJ, Amyx HL, Bacote A, Masters CL, Gajdusek DC (1980) Oral transmission of kuru, Creutzfeldt-Jakob disease, and scrapie to nonhuman primates. J Infect Dis 142:205-208
15. 15. Groschup MH, Weiland F, Straub OC, Pfaff E (1996) Detection of scrapie agent in the peripheral nervous system of a diseased sheep. Neurobiol Dis 3:191-195
16. 16. Hill AF, Butterworth RJ, Joiner S, Jackson G, Rossor MN, Thomas DJ, Frosh A, Tolley N, Bell JE, Spencer M, King A, Al Sarraj S, Ironside JW, Lantos PL, Collinge J (1999) Investigation of variant Creutzfeldt-Jakob disease and other human prion diseases with tonsil biopsy samples. Lancet 353:183-189
17. 17. Hilton DA, Fathers E, Edwards P, Ironside JW, Zajicek J (1998) Prion immunoreactivity in appendix before clinical onset of variant Creutzfeldt-Jakob disease. Lancet 352:703-704
18. 18. Horiuchi M, Caughey B (1999) Specific binding of normal prion protein to the scrapie form via a localized domain initiates its conversion to the protease resistant state. EMBO J 18:3193-3202
19. 19. Horiuchi M, Yamazaki N, Ikeda T, Ishiguro N, Shinagawa M (1995) A cellular form of prion protein (PrPC) exists in many non-neuronal tissues of sheep. J Gen Virol 76:2583-2587
20. 20. JimenezHuete A, Lievens PMJ, Vidal R, Piccardo P, Ghetti B, Tagliavini F, Frangione B, Prelli F (1998) Endogenous proteolytic cleavage of normal and disease-associated isoforms of the human prion protein in neural and non-neural tissues. Am J Pathol 153:1561-1572
21. Sc)-specific epitope defined by a monoclonal antibody. Nature 390:74-77
22. 22. Kuwahara C, Takeuchi AM, Nishimura T, Haraguchi K, Kubosaki A, Matsumoto Y, Saeki K, Matsumoto Y, Yokoyama T, Itohara S, Onodera T (1999) Prions prevent neuronal cell death. Nature 400:225-226
23. 23. Mabbott NA, Brown KL, Manson J, Bruce ME (1997) T-lymphocyte activation and the cellular form of the prion protein. Immunology 92:161-165
24. 24. McBride PA, Beekes M (1999) Pathological PrP is abundant in sympathetic and sensory ganglia of hamsters fed with scrapie. Neurosci Lett 265:135-138
25. 25. Pammer J, Exner M, Regele H, Haitel A, Weninger W, Horvat R, Susani M (1998) Expression of bcl-2, bcl-x, bax and bak in renal parenchyma, oncocytomas and renal cell carcinomas. Pathol Res Pract 194:837-845
26. 26. Pammer J, Weninger W, Tschachler E (1998) Human keratinocytes express cellular prion-related protein in vitro and during inflammatory skin diseases. Am J Pathol 153:1353-1358
27. 27. Prusiner SB (1998) Prions. Proc Natl Acad Sci USA 95:13363-13383
28. 28. Raeber AJ, Klein MA, Frigg R, Flechsig E, Aguzzi A, Weissmann C (1999) PrP-dependent association of prions with splenic but not circulating lymphocytes of scrapie-infected mice. EMBO J 18:2702-2706
29. 29. Ridley RM, Baker HF (1998) Fatal protein. Oxford University Press, Oxford
30. 30. Tong WM, Ellinger A, Sheinin Y, Cross HS (1998) Epidermal growth factor receptor expression in primary cultured human colorectal carcinoma cells. Br J Cancer 77:1792-1798
31. 31. Van Keulen LJ, Schreuder BE, Meloen RH, Mooij Harkes G, Vromans ME, Langeveld JP (1996) Immunohistochemical detection of prion protein in lymphoid tissues of sheep with natural scrapie. J Clin Microbiol 34:1228-12231
32. 32. Wells GA, Hawkins SA, Green RB, Austin AR, Dexter I, Spencer YI, Chaplin MJ, Stack MJ, Dawson M (1998) Preliminary observations on the pathogenesis of experimental bovine spongiform encephalopathy (BSE): an update. Vet Rec 142:103-106
33. 33. Will RG, Ironside JW, Zeidler M, Cousens SN, Estibeiro K, Alperovitch A, Poser S, Pocchiari M, Hofman A, Smith PG (1996) A new variant of Creutzfeldt-Jakob disease in the UK. Lancet 347:921-925