Phospholipid transfer proteins and physiological functions

International Review of Cytology

Volumn 197, Issue , 2000, Pages 35-81

  Rogers, Danise P ^a   Bankaitis, Vytas A ^a  

^a UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

Author keywords

Phospholipids; Signal transduction; Transfer proteins

Indexed keywords

GLYCOLIPID; LIPID; LIPID TRANSFER PROTEIN; PHOSPHATIDYLCHOLINE; PHOSPHATIDYLINOSITOL; PHOSPHATIDYLSERINE; PHOSPHOLIPID TRANSFER PROTEIN;

BIOCHEMISTRY; CELL FUNCTION; CELL MEMBRANE; CRYSTAL STRUCTURE; CYTOSOL; EUKARYOTE; EXOCYTOSIS; GOLGI COMPLEX; LIPID COMPOSITION; LIPID METABOLISM; LYSOSOME; MEMBRANE TRANSPORT; MEMBRANE VESICLE; NEUROPROTECTION; NONHUMAN; PHYSIOLOGY; PRIORITY JOURNAL; PROTEIN STRUCTURE; REVIEW; SECRETORY GRANULE; SIGNAL TRANSDUCTION; YEAST;

EUKARYOTA; MAMMALIA;

EID: 0034063298     PISSN: 00747696     EISSN: None     Source Type: Book Series    
DOI: 10.1016/s0074-7696(00)97002-5     Document Type: Review

References (200)

1. Abe, A. (1990). Primary structure of glycolipid transfer protein from pig brain. J. Biol. Chem. 265, 9634-9637.
2. Abe, A., and Sasaki, T. (1985). Purification and some properties of the glycolipid transfer protein from pig brain. J. Biol. Chem. 260, 11231-11239.
3. 2+-catalyzed oxidation. Biochim. Biophys. Acta 985, 38-44.
4. Abe, A., and Sasaki, T. (1989b). Formation of an intramolecular bond of glycolipid transfer protein. Biochim. Biophys. Acta 985, 45-50.
5. Abe, A., Yamada, K., and Sasaki, T. (1982). A protein purified from pig brain accelerates the intermembranous translocation of mono- and dihexosylceramides, but not the translocation of phospholipids. Biochim. Biophys. Acta 104, 1386-1393.
6. Aikawa, Y., Kuraoka, A., Kondo, H., Kawabuchi, M., and Watanabee, T. (1999). Involvement of PITPnm, a mammalian homologue of Drosophila rdgB, in phosphoinositide synthesis on Golgi membrane. J. Biol. Chem. 274, 20569-20577.
7. Akeroyd, R., Moonen, P., Westerman, J., Puijk, W. C., and Wirtz, K. W. A. (1981). The complete primary structure of phosphatidylcholine transfer protein from bovine liver. Eur. J. Biochem. 114, 385-391.
8. Alb, J. G. Jr., Gedvilaite, A., Cartee, R. T., Skinner, H. B., and Bankaitis, V. A. (1995). Mutant rat phosphatidylinositol/phosphatidylcholine transfer proteins specifically defective in phosphatidylinositol transfer: Implications for the regulation of phospholipid transfer activity. Proc. Natl. Acad. Sci. USA 92, 8826-8830.
9. Alb, J. G. Jr., Kearns, M. A., and Bankaitis, V. A. (1996). Phospholipid metabolism and membrane dynamics. Curr. Opin. Cell Biol. 8, 534-541.
10. Albers, J. J., Tu, A.-Y., Wolfbauer, G., Cheung, M. C., and Marcovina, S. M. (1996). Molecular biology of phospholipid transfer proteins. Curr. Opin. Lipidol. 7, 88-93.
11. 2+ ion concentrations. Biochem. J. 327, 545-552.
12. Askin, F. B., and Kuhn, C. (1971). The cellular origin of pulmonary surfactant. Lab. Invest. 25, 260-268.
13. Bankaitis, V. A., Malehorn, D. E., Emr, S. D., and Greene, R. (1989). The Saccharomyces cerevisiae SEC14 gene encodes a cytosolic factor that is required for transport of secretory proteins from the yeast Golgi complex. J. Cell Biol. 108, 1271-1281.
14. Bankaitis, V. A., Aitken, J. R., Cleves, A. E., and Dowhan, W. (1990). An essential role for a phospholipid transfer protein in yeast Golgi function. Nature 347, 561-562.
15. Bankaitis, V. A., Fry, M. R., Cartee, R. T., and Kagiwada, S. (1996). General mechanism for lipid transport and sorting. In "Phospholipid Transfer Proteins: Emerging Roles in Vesicle Trafficking Signal Transduction and Metabolic Regulation," pp. 4-18. R. G. Landes Company, Austin, TX.
16. Batty, I. H., Currie, R. A., and Downes, C. P. (1998). Evidence for a model of integrated inositol phospholipid pools implies an essential role for lipid transport in the maintenance of receptor-mediated phospholipase C activity in 1321N1 cells. Biochem. J. 330, 1069-1077.
17. Baum, C. L., Reschly, E. J., Gayen, A. K., Groh, M. E., and Schadick, K. (1997). Sterol carrier protein-2 overexpression enhances sterol cycling and inhibits cholesterol ester synthesis and high density lipoprotein cholesterol secretion. J. Biol. Chem. 272, 6490-6498.
18. Berkhout, T. A., Visser, A. J. W. G., and Wirtz, K. W. A. (1984). Static and time-resolved fluorescence studies of fluorescent phosphatidylcholine bound to phosphatidylcholine transfer protein of bovine liver. Biochemistry 23, 1505-1513.
19. Bernhard, W. R., and Sommerville, C. R. (1989). Coidentity of putative amylase inhibitors from barley and finger millet with phospholipid transfer proteins inferred from amino acid sequence homology. Arch. Biochem. Biophys. 269, 695-697.
20. Bi, K., Roth, G., and Ktistakis, N. T. (1997). Phosphatidic acid formation by phospholipase D is required for transport from the endoplasmic reticulum to the Golgi complex. Curr. Biol. 7, 301-307.
21. Bloj, B., and Zilversmit, D. B. (1977). Rat liver protein capable of transferring phosphatidylethanolamine: Purification and transfer activity for other phospholipids and cholesterol. J. Biol. Chem. 252, 1613-1619.
22. Brown, R. E. (1992). The spontaneous transfer of lipids between membranes. In Subcellular Biochemistry, Vol. 16 (H. J. Hilderson, Ed.), pp. 333-363. Plenum Press, New York.
23. Brown, R. E., Stephenson, F. A., Markello, T., Barenholz, Y., and Thompson, T. E. (1985). Properties of a specific glycolipid transfer protein from bovine brain. Chem. Phys. Lipids 38, 79-93.
24. Brown, R. R., Jarvis, K. L., and Hyland, K. J. (1990). Purification and characterization of glycolipid transfer protein from bovine brain. Biochim. Biophys. Acta 1044, 77-83.
25. Carmen-Lopez, M., Nicaud, J.-M., Skinner, H. B., Vergnolle, C., Kader, J. C., Bankaitis, V. A., and Gaillardin, C. (1994). A phosphatidylinositol/phosphatidylcholine transfer protein is required for differentiation of the dimorphic yeast Yarrowia lipolytica from the yeast to the mycelial form. J. Cell Biol. 124, 113-127.
26. Chang, J. T., Milligan, S., Li, Y., Chew, C. E., Wiggs, J., Copeland, N. G., Jenkins, N. A., Campochiaro, P. A., Hyde, D. A., and Zack, D. J. (1997). Mammalian homologue of Drosophila retinal degeneration B rescues the mutant fly phenotype. J. Neurosci. 17, 5881-5890.
27. Chen, S. F., Chung. Y. J., and Wu, W. (1991). Phosphatidylcholine transfer protein from porcine liver. Biochem. Int. 23, 377-382.
28. Chen, Y.-G., Siddhanta, A., Austin, C. D., Hammond, S. M., Sung, T.-C., Frohman, M. A., Morris, A. J., and Shields, D. (1997). Phospholipase D stimulates release of nascent secretory vesicles from the trans-Golgi network. J. Cell Biol. 138, 495-504.
29. Chinen, K., Takahashi, E., and Nakamura, Y. (1996). Isolation and mapping of a human gene (SEC14L), partially homologous to yeast SEC14, that contains a variable number of tandem repeat (VTNR) sites in its 3′ untranslated region. Cytogenet Cell Genet. 73, 218-223.
30. Cleves, A. E., Novick, P. J., and Bankaitis, V. A. (1989). Mutations in the SAC1 gene suppress defects in yeast Golgi and yeast actin function. J. Cell. Biol. 109, 2939-2950.
31. Cleves, A. E., McGee, T. P., Whitters, E. A., Champion, K. M., Aitken, J. R., Dowhan, W., Goebl, M., and Bankaitis, V. A. (1991). Mutations in the CDP-choline pathway for phospholipid biosynthesis bypass the requirement for an essential phospholipid transfer protein. Cell 64, 789-800.
32. Cockcroft, S. (1998). Phosphatidylinositol transfer proteins: A requirement in signal transduction and vesicle traffic. BioEssays 20, 423-432.
33. Cockcroft, S., Ball, A., Fensome, A., Hara, S., Jones, D., Prosser, S., and Swigart, P. (1997). Phosphatidylinositol transfer proteins: An essential requirement in inositol lipid signaling. Biochem. Soc. Trans. 25, 1125-1130.
34. Cohen, D. E., Leonard, M. R., and Carey, M. C. (1994). In vitro evidence that phospholipid secretion into bile may be coordinated intracellularly by the combined actions of bile salts and the specific phosphatidylcholine transfer protein of the liver. Biochemistry 33, 9975-9980.
35. 2. Eur. J. Biochem. 123, 455-464.
36. Cullis, P. R., and Hope, M. J. (1991). Physical properties and functional roles of lipids in membranes. In "Biochemistry of Lipids, Lipoproteins and Membranes" (D. E. Vance and J. Vance, Eds.), pp. 1-40. Elsevier Sciences Publishers, Amsterdam.
37. 2. Curr. Biol. 5, 775-783.
38. Cunningham E., Tan, S. K., Swigart, P., Hsuan, J., Bankaitis, V., and Cockcroft, S. (1996). The yeast and mammalian isoforms of phosphatidylinositol transfer protein can all restore phospholipase C-mediated inositol lipid signaling in cytosol-depleted RBL-2H3 and HL-60 cells. Proc. Natl. Acad. Sci. USA 93, 6589-6593.
39. Daum, G., and Paltauf, F. (1984). Phospholipid transfer protein in yeast: Isolation and partial characterization of a phospholipid transfer protein from yeast cytosol. Biochim. Biophys. Acta 794, 385-391.
40. Day, J. R., Albers, J. J., Lofton-Day, C. E., Gibert, T. L., Ching, A. F. T., Grant, F. J., O'Hara, P. J., Marcovina, S. M., and Adolphson, J. L. (1994). Complete cDNA encoding human phospholipid transfer protein from human endothelial cells. J. Biol. Chem. 269, 9388-9391.
41. Del Vecchio, R. L., and Tonks, N. K. (1994). Characterization of two structurally related Xenopus laevis protein tyrosine phosphatases with homology to lipid binding proteins. J. Biol. Chem. 269, 19639-19645.
42. Demel, R. A., Wirtz, K. W. A., Kamp, H. H., Geurts van Kessel, W. S. M., and van Deenen, L. L. M. (1973). Phosphatidylcholine exchange protein from beef liver. Nat. New Biol. 246, 102-105.
43. Demel, R. A., Kalsbeek, R., Wirtz, K. W. A., and van Deenen, L. L. M. (1977). The protein- mediated net transfer of phosphatidylinositol in model systems. Biochim. Biophys. Acta 466, 10-22.
44. Desormeaux, A., Blochet, J. E., Pezolet, M., and Marion, D. (1992). Amino acid sequence of a non-specific wheat phospholipid transfer protein and its conformation as revealed by infrared and Raman spectroscopy. Role of disulfide bridges and phospholipids in the stabilization of α-helix structure. Biochim. Biophys. Acta 1121, 137-152.
45. Desrumaux, C., Athias, A., Masson, D., Gambert, P., Lallemant, C., and Lagrost, L. (1998). Influence of the electrostatic charge of lipoprotein particles on the activity of the human plasma phospholipid transfer protein. J. Lipid Res. 39, 131-142.
46. de Vries, K. J., Heinrichs, A. J. A., Cunningham, E., Brunink, R., Westerman, J., Somerharju, P. J., Cockcroft, S., Wirtz, K. W. A., and Snoek, G. T. (1995). An isoform of the phosphatidylinositol-transfer proteins transfers sphingomyelin and is associated with the Golgi system. Biochem. J. 310, 643-649.
47. Dickeson, S. K., Lim, C. N., Schuyler, G. T., Dalton, T. P., Helmkamp, G. M. Jr., and Yarbrough, L. R. (1989). Isolation and sequence of cDNA clones encoding rat phosphatidylinositol transfer protein. J. Biol. Chem. 264, 16557-16564.
48. Douady, D., Grosbois, M., Guerbette, F., and Kader, J. C. (1982). Purification of a basic phospholipid transfer protein from maize seedlings. Biochim. Biophys. Acta 710, 143-155.
49. Dove, S. K., Cooke, F. T., Douglas, M. R., Sayters, L. G., Parker, P. J., and Michel, R. H. (1997). Osmotic stress activates phosphatidylinositol-3,5-bisphosphate synthesis. Nature 390, 187-192.
50. Dyatlovitskaya, E. V., Timofeeva, N. G., Yakimenko, E. F., Barsukov. L. I., Muzya, G. I., and Bergelson, L. D. (1982). A sphingomyelin transfer protein in rat tumors and fetal liver. Eur. J. Biochem. 123, 311-315.
51. Einholm, C., and Zilversmit, D. B. (1973). Exchange of various phospholipids and cholesterol between liposomes in the presence of highly purified phospholipid exchange protein. J. Biol. Chem. 248, 1719-1724.
52. Fang, M., Kearns, B. G., Gedvilaite, A., Kagiwada, S., Kearns, M., Fung, M. K. Y. and Bankaitis, V. A. (1996). Kes1p shares homology with human oxysterol binding protein and participates in a novel regulatory pathway for yeast Golgi-derived transport vesicle biogenesis. EMBO J. 15, 6447-6459.
53. 2 synthesis. Curr. Biol. 6, 730-738.
54. Fischer, G., and Jatzkewitz, H. (1978). The activator of cerebroside-sulphatase: A model of activation. Biochim. Biophys. Acta 528, 69-76.
55. Frolov, A., Miller, K., Billheimer, J. T., Cho, T.-H., and Schroeder, F. (1997). Lipid specificity and location of the sterol carrier protein-2 fatty acid-binding site: A fluorescence displacement and energy transfer study. Lipids 32, 1201-1209.
56. Fürst, W., and Sandhoff, K. (1992). Activator proteins and topology of lysosomal sphingolipid catabolism. Biochim. Biophys. Acta 1126, 1-16.
57. 2 activator protein and cerebroside sulfate activator protein. Eur. J. Biochem. 192, 709-714.
58. Gadella, T. W. J. Jr., and Wirtz, K. W. A. (1990). The low-affinity lipid binding site of the nonspecific lipid transfer protein: Implications for its mode of action. Biochim. Biophys. Acta 1070, 237-245.
59. Gadella, T. W. J. Jr., and Wirtz, K. W. A. (1994). Phospholipid binding and transfer by the nonspecific lipid-transfer protein (sterol carrier protein 2): A kinetic model. Eur. J. Biochem. 220, 1019-1020.
60. Gadella, T. W. J. Jr., Bastiaens, P. I. H., Visser, A. J. W. G., and Wirtz, K. W. A. (1991). Shape and lipid-binding site of the nonspecific lipid transfer protein (sterol carrier protein 2): A steady-state and time-resolved fluorescence study. Biochemistry 30, 5555-5564.
61. Gaigg, B., Lafer, G., and Daum, G. (1993). Interaction of the yeast phosphatidylserine transfer protein with artificial and biological membranes. Biochim. Biophys. Acta 1146, 301-304.
62. Geijtenbeek, T. B. H., De Groot, E., Van Baal, J., Brunink, R., Westerman, J., Snoek, G. T., and Wirtz, K. W. A. (1994). Characterization of mouse phosphatidylinositol transfer protein expressed in Escherichia coli. Biochim. Biophys. Acta 1213, 309-318.
63. Geijtenbeck, T. B. H., Smith, A. J., Borst, P., and Wirtz, K. W. A. (1996a). cDNA cloning and tissue-specific expression of the phosphatidylcholine transfer protein gene. Biochem. J. 316, 46-55.
64. Geijtenbeek, T. B. H., Westerman, J., Heerma, W., and Wirtz, K. W. A. (1996b). Phosphatidylcholine transfer protein from bovine liver contains highly unsaturated phosphatidylcholine species. FEBS Lett. 391, 333-335.
65. George, P. Y., and Helmkamp, G. M. Jr. (1985). Purification and characterization of a phosphatidylinositol transfer protein from human platelets. Biochim. Biophys. Acta 836, 176-184.
66. Godi, A., Santone, I., Pertile, P., Devarajan, P., Stabach, P. R., Morrow, J. S., Di Tulle, G., Polischuk, R., Petrucci, T. C., Luini, A., and De Matteis, M. A. (1998). ADP ribosylation factor regulates spectrin binding to the Golgi complex. Proc. Natl. Acad. Sci. USA 95, 8607-8612.
67. Gu, M., Warshawsky, I., and Majerus, P. W. (1992). Cloning and expression of a cytosolic megakaryocyte protein tyrosine-phosphatase with sequence homology to retinaldehyde- binding protein and yeast SEC14p. Proc. Natl. Acad. Sci. USA 89, 2980-2984.
68. Guo, S., Stolz, L. E., Lemrow, S., and York, J. D. (1999). SAC1-like domains of yeast SAC1, INP52, and INP53, and human synaptojanin encode polyphosphoinositide phosphatases. J. Biol. Chem. 274, 12990-12995.
69. Hagerman, J. S., and Gould, R. G. (1951). The in vitro exchange of cholesterol between plasma and red blood cells, Proc. Soc. Exp. Biol. Med. 78, 329-332.
70. Hahn, L., and Hevesy, G. (1939). Phosphatide exchange between plasma and organs, Nature 144, 204-205.
71. Hallman, M., and Gluck, L. (1975). Phosphatidylglycerol in lung surfactant: Subcellular distribution and mechanism of biosynthesis in vitro. Biochim. Biophys. Acta 409, 172-191.
72. Hamilton, B. A., Smith, D. J., Mueller, K. L., Kerrebrock, A. W., Bronson, R. T., van Berkel, V., Daly, M. J., Druglayak, L., Reeve, M. P., Nemhauser, J. L., Hawkins, T. L., Rubin, E. M., and Lander, E. S. (1997). The vibrator mutation causes neurodegeneration via reduced expression of PITPα: Positional complementation cloning and extragenic suppression. Neuron 18, 711-722.
73. Hara, S., Swigart, P., Jones, D., and Cockcroft, S. (1997). The first 5 amino acids of the carboxyl terminus of phosphatidylinositol transfer protein (PITP)α play a critical role in inositol lipid signaling: Transfer activity of PITP is essential but not sufficient for restoration of phospholipase C signaling. J. Biol. Chem. 272, 14908-14913.
74. Harris, W. A., and Stark, W. S. (1977). Hereditary retinal degeneration in Drosophila melanogaster. A mutant defect associated with the phototransduction process. J. Gen. Physiol. 69, 261-291.
75. Hay, J. C., and Martin, T. F. J. (1992). Resolution of regulated secretion into sequential MgATP-dependent and calcium-dependent stages mediated by distinct cytosolic proteins. J. Cell Biol. 119, 139-151.
76. 2+ activated secretion. Nature 366, 572-575.
77. 2+-activated secretion. Nature 374, 173-177.
78. Hay, J. C., Chao, D. S., Kuo, C. S., and Scheller, R. H. (1997). Protein interactions regulating vesicle transport between the endoplasmic reticulum and Golgi apparatus in mammalian cells. Cell 89, 149-158.
79. Heinemann, B., Anderson, K. V., Nielsen, P. R., Bech, L. M., and Poulsen, F. M. (1996). Structure in solution of a four-helix lipid binding protein. Protein Sci. 5, 13-23.
80. Helmkamp, G. M., Jr. (1980). Concerning the mechanism of action of bovine liver phospholipid exchange protein: Exchange or net transfer. Biochem. Biophys. Res. Commun. 97, 1091-1096.
81. Helmkamp, G. M., Jr. (1985). Phospholipid transfer proteins: Mechanism of action. J. Bioenerg. Biomembranes 18, 71-90.
82. Helmkamp, G. M. Jr., Garvey, M. S., Wirtz, K. W. A., and van Deenen, L. L. M. (1974). Phospholipid exchange between membranes: Purification of bovine brain proteins that preferentially catalyze the transfer of phosphatidylinositol. J. Biol. Chem. 249, 6382-6389.
83. Hotta, Y., and Benzer, S. (1970). Genetic dissection of the Drosophila nervous system by means of mosaics. Proc. Natl. Acad. Sci. USA 67, 1156-1163.
84. Hsuan, J. J., and Tan, S. H. (1997). Growth factor-dependent phosphoinositide signaling. Int. J. Biochem. Cell Biol. 29, 415-435.
85. Jenkins, G. H., Fisette, P. L., and Anderson, R. A. (1994). Type I phosphatidylinositol 4-phosphate 5-kinase isoforms are specifically stimulated by phosphatidic acid. J. Biol. Chem. 269, 11547-11554.
86. Jones, S. M., Alb, J. G. Jr., Phillips, S. E., Bankaitis, V. A., and Howell, K. E. (1998). A phosphatidylinositol 3-kinase and phosphatidylinositol transfer protein act synergistically in formation of constitutive transport vesicles from the trans-Golgi network. J. Biol. Chem. 273, 10349-10354.
87. Kader, J. J. (1990). Intracellular transfer of lipid molecules. In "Subcellular Biochemistry" (H. J. Hilderson, Ed.), pp. 69-111. Plenum Press, New York.
88. Kagiwada, S., Kearns, B. G., McGee, T. P., Fang, M., Hosaka, K., and Bankaitis, V. A. (1996). The yeast BSD2-1 mutation influences both the requirement for phosphatidylinositol transfer protein function and derepression of phospholipid biosynthetic gene expression in yeast. Genetics 143, 685-697.
89. Kahn, R. A., Yucel, J. K., and Malhotra, V. (1993). ARF-signaling: A potential role for phospholipase D in membrane traffic. Cell 79, 1045-1048.
90. Kamp, H. H., Wirtz, K. W. A., Baer, P. R., Slotboom, A. J., Rosenthal, A. F., and van Deenen, L. L. M. (1977). Specificity of the phosphatidylcholine exchange protein from bovine liver. Biochemistry 16, 1310-1316.
91. Kaplan, M. R., and Simoni, R. D. (1985). Intracellular transport of phosphatidylcholine to the plasma membrane. J. Cell Biol. 101, 441-445.
92. Kasper, A. M., and Helmkamp, G. M. Jr. (1981). Intermembrane phospholipid fluxes catalyzed by bovine brain phospholipid exchange protein. Biochim. Biophys. Acta 664, 22-32.
93. Kasurinen, J., van Paridon, P. A., and Wirtz, K. W. A. (1990). Affinity of phosphatidylcholine molecular species for the bovine phosphatidylcholine and phosphatidylinositol transfer protein. Properties of the sn-1 and sn-2 acyl binding sites. Biochemistry 29, 8548-8554.
94. Kearns, B. G., McGee, T. P., Mayinger, P., Gedvilaite, A., Phillips, S. E., Kagiwada, S., and Bankaitis, V. A. (1997). Essential role for diacylglycerol in protein transport from the yeast Golgi complex. Nature 387, 101-105.
95. Kearns, M. A., Monks, D. E., Fang, M., Rivas, M. P., Courtney, P. D., Chen, J., Prestwich, G. D., Theibert, A. B., Dewey, R. E., and Bankaitis, V. A. (1998). Novel developmentally regulated phosphoinositide binding proteins from soybean whose expression bypasses the requirement for an essential phosphatidylinositol transfer protein in yeast. EMBO J. 17, 4004-4017.
96. Keller, G. A., Scallen, T. J., Clarke, D., Maher, P. A., Krisans, S. K., and Singer, S. J. (1989). Subcellular localization of sterol carrier protein-2 in rat hepatocytes: Its primary localization to peroxisomes. J. Cell Biol. 108, 1353-1361.
97. Keller, P., and Simons, K. (1997). Post-Golgi biosynthetic trafficking. J. Cell Sci. 110, 3001-3009.
98. Kesav, S., McLaughlin, J., and Scallen, T. J. (1992). Participation of sterol carrier protein-2 in cholesterol metabolism. Biochem. Soc. Trans. 20, 818-824.
99. Khan, Z. U., and Helmkamp, G. M. Jr. (1990). Stimulation of cholinephosphotransferase activity by phosphatidylcholine transfer protein: Regulation of membrane phospholipid synthesis by a cytosolic protein. J. Biol. Chem. 265, 700-706.
100. Koumanov, K., Boyanov, A., Neicheva, T., Markovska, T., Momchilove, A., Gavzova, E., and Chelibonova-Lorer, H. (1982). Phospholipid composition of subcellular fractions and phospholipid-exchange activity in chicken liver and MC-29 hepatoma: Biochim. Biophys. Acta 713, 23-28.
101. Ktistakis, N. T., Brown, H. A., Waters, M. B., Sternweis, P. C., and Roth, M. G. (1996). Evidence that phospholipase D mediates ADP ribosylation factor-dependent formation of Golgi-coated vesicles. J. Cell Biol. 134, 295-306.
102. Lafer, G., Szolderits, G., Paltauf, F., and Daum, G. (1991). Isolation of a phosphatidylserine transfer protein from yeast cytosol. Biochim. Biophys. Acta 1069, 139-144.
103. Lee, J. Y., Min, K., Cha, H., Shin, D. H., Hwang, K. Y., and Suh, S. W. (1998). Rice nonspecific lipid transfer protein: The 1.6 Å crystal structure in the unliganded state reveals a small hydrophobic cavity. J. Mol. Biol. 276, 437-448.
104. 2 hydrolysis and regulation of phospholipase C isozyme. Curr. Opin. Cell Biol. 7, 183-189.
105. Li, S. C., and Li, Y. T. (1976). An activator stimulating the enzymic hydrolysis of sphingolipids. J. Biol. Chem. 251, 1159-1163.
106. 2 ganglioside. J. Biol. Chem. 256, 6234-6240.
107. Liscovitch, M., and Cantley, L. C. (1995). Signal transduction and membrane traffic: The PITP/phosphoinositide connection. Cell 81, 659-662.
108. Liscovitch, M., Chalifa, V., Pertile, P., Chen, C.-S., and Cantley, L. C. (1994). Novel function of phosphatidylinositol 4,5-bisphosphate as a cofactor for brain membrane phospholipase D. J. Biol. Chem. 269, 21403-21406.
109. Loyet, K. M., Kowalchyk, J. A., Chaudhary, A., Chen, J., Prestwich, G. D., and Martin, T. F. J. (1998). Specific binding of phosphatidylinositol 4,5-bisphosphate to CAPS, a potential phosphoinositide effector protein for exocytosis. J. Biol. Chem. 273, 8337-8343.
110. Lumb, R. H., Cottle, D. A., White, L. C., Hoyle, S. N., Pool, G. L., and Brumley, G. W. (1980). Lung phosphatidylcholine transfer in six vertebrate species: Correlations with surfactant parameters. Biochim. Biophys. Acta 620, 172-175.
111. Martin, T. F. J. (1997). Phosphoinositides as spatial regulators of membrane traffic. Curr. Opin. Neurobiol. 7, 331-338.
112. 3 pituitary cells. J. Biol. Chem. 264, 10299-10308.
113. McGee, T. P., Skinner, H. B., Whitters, E. A., and Bankaitis, V. A. (1994). A phosphatidylinositol transfer protein controls the phosphatidylcholine content of yeast Golgi membranes. J. Cell Biol. 124, 273-287.
114. McMurray, W. C., and Dawson, R. M. C. (1969). Phospholipid exchange reactions within the liver. Biochem. J. 112, 91-108.
115. McPherson P. S., Garcia, E. P., Slepnev, V. I., David, C., Zhang, X., Grabs, D., Sossin, W. S., Bauerfeind, R., Nemoto, Y., and De Camilli P. (1996). A presynaptic inositol-5-phosphatase. Nature 379, 353-357.
116. 2 activator protein: A substrate specific cofactor of β-hexosaminidase A. J. Biol. Chem. 266, 1879-1887.
117. Metz, R., and Radin, N. S. (1982). Purification and properties of a cerebroside transfer protein. J. Biol. Chem. 257, 12910-12907.
118. Milligan, S. C., Alb, J. G., Jr., Elagina, R., Bankaitis, V. A., and Hyde, D. R. (1997). The phosphatidylinositol transfer protein domain of Drosophila retinal degeneration B protein is essential for photoreceptor cell survival and recovery from light stimulation. J. Cell Biol. 139, 351-363.
119. Monaco, M. E., and Gershengorn, M. C. (1992). Subcellular organization of receptor-mediated phosphoinositide turnover. Endocr. Rev. 13, 707-718.
120. Moncecchi, D., Pastuszyn, A., and Scallen, T. J. (1991). cDNA sequence and bacterial expression of mouse liver sterol carrier protein-2. J. Biol. Chem. 266, 9885-9892.
121. Moonen, P., Haagsman, H. P., van Deenen, L. L. M., and Wirtz, K. W. A. (1979). Determination of the hydrophobic binding site of phosphatidylcholine exchange protein with photosensitive phosphatidylcholine. Eur. J. Biochem. 99, 439-445.
122. Moreau, P., and Cassagne, C. (1994). Phospholipid trafficking and membrane biogenesis. Biochim. Biophys. Acta 1197, 257-290.
123. Nishida, H. I., and Nishida, T. (1997). Phospholipid transfer protein mediates the transfer of not only phosphatidylcholine but also cholesterol from phosphatidylcholine-cholesterol vesicles to high density lipoproteins. J. Biol. Chem. 272, 6959-6964.
124. Ohashi, M., de Vries, K. J., Frank, R., Snoek, G., Bankaitis, V., Wirtz, K., and Huttner, W. B. (1995). A role for phosphatidylinositol transfer protein in secretory vesicle formation. Nature 377, 544-547.
125. Panaretou, C., Domin, J., Cockcroft, S., and Waterfield, M. D. (1997). Characterization of p150, an adapter protein for the human phosphatidylinositol (PtdIns) 3-kinase. Substrate presentation by phosphatidylinositol transfer protein to the p150-PtdIns 3-kinase complex. J. Biol. Chem. 272, 2477-2485.
126. Paul, K. S., Bogan, A. A., and Waters, M. G. (1998). Phosphatidylinositol transfer protein (PITPα) stimulates in vitro intra-Golgi transport. FEBS Lett. 431, 91-96.
127. Pike, L. J., and Casey, L. (1996). Localization and turnover of phosphatidylinositol 4,5-bisphosphate in caveolin-enriched membrane domains. J. Biol. Chem. 271, 26453-26456.
128. Poorthuis, B. J. H. M., and Wirtz, K. W. A. (1983). Nonspecific transfer lipid transfer protein from rat liver. Methods Enzymol. 98, 592-596.
129. Poorthuis, B. J. H. M., Van der Krift, T. P., Teelink, T., Akeroyd, R., Hostetler, K. Y., and Wirtz, K. W. A. (1980). Phospholipid transfer activities in Morris hepatomas and the specific contribution of the phosphatidylcholine exchange proteins. Biochim. Biophys. Acta 600, 376-386.
130. Prosser, S., Sarra, R., Swigart, P., Ball, A., and Cockcroft, S. (1997). Deletion of 24 amino acids from the C-terminus of phosphatidylinositol transfer protein causes loss of phospholipase C- mediated inositol lipid signaling. Biochem. J. 324, 19-23.
131. Pryer, N. K., Wuestehube, L. J., and Schekman, R. (1992). Vesicle-mediated protein sorting. Annu. Rev. Biochem. 61, 471-516.
132. Rivas, M. P., Kearns, B. G., Xie, Z., Guo, S., Sekar, M. C., Hosaka, K., Kagiwada, S., York, J. D. and Bankaitis, V. A. (1999). Pleiotropic alterations in lipid metabolism in yeast sac1 mutants: Relationship to 'bypass Sec14p' and inositol auxotrophy. Mol. Biol. Cell 10, 2235-2250.
133. Rothman, J. E. (1994). Mechanisms of intracellular protein transport. Nature 372, 55-63.
134. Rueckart, D. G., and Schmidt, K. (1990). Lipid transfer proteins. Chem. Phys. Lipids 56, 1-20.
135. Runquist, E. A., and Helmkamp, G. M. Jr. (1988). Effect of acceptor membrane phosphatidylcholine on the catalytic activity of bovine liver phosphatidylcholine transfer protein. Biochim. Biophys. Acta 940, 21-32.
136. Salama, S. R., Cleves, A. E., Malehorn, D. E., Whitters, E. A., and Bankaitis, V. A. (1990). Cloning and characterization of Kluyveromyces lactis SEC14, a gene whose product stimulates Golgi secretory function in Saccharomyces cerevisiae. J. Bacteriol. 172, 4510-4521.
137. Sasaki, T. (1990). Glycolipid transfer protein and intracellular traffic of glucosylceramide. Experientia 46, 611-616.
138. Sasaki, T., and Demel, R. A. (1985). Net mass transfer of galactosylceramide facilitated by glycolipid transfer protein from pig brain: A monolayer study. Biochemistry 24, 1079-1083.
139. Sasaki, T., Abe, A., and Roerink, F. (1990). Glycolipid transfer protein in animal cells. In "Subcellular Biochemistry" (H. J. Hilderson, Ed.), pp. 129-174. Plenum Press, New York.
140. Sato, Y., Arai, H., Miyata, A., Tokita, S., Yamamoto, K., Tananbe, T., and Inoue, K. (1993). Primary structure of α-tocopherol transfer protein from rat liver. Homology with cellular retinaldehyde protein. J. Biol. Chem. 268, 17705-17710.
141. Scallen, T. J., Pastuszym, A., Noland, B. J., Chanderbhan, R., Karroubi, A., and Vahouny, G. V. (1985). Sterol carrier and lipid transfer proteins. Chem. Phys. Lipids 38, 239-261.
142. Schlote, W., Harzer, K., Christomanou, H., Paton, B. C., Kustermann-Kuhn, B., Schmid, B., Seeger, J., Beudt, U., Schuster, I., and Langenbeck, U. (1991). Sphingolipid activator protein deficiency in metachromatic leukodystrophy with normal arylsulphatase A activity: A clinical, morphological, biochemical and immunological study. Eur. J. Pediatr. 150, 584-591.
143. Schroeder, F., Frolov. A., Murphy, E., Atshaves, B. P., Jefferson, J. R., Pu, L., Wood, W. G., Foxworth, W. B., and Kier, A. B. (1996). Recent advances in membrane cholesterol domain dynamics and intracellular cholesterol trafficking. Proc. Soc. Exp. Biol. Med. 213, 150-177.
144. Schu, P. V., Takegawa, K., Fry, M. J., Stack, J. H., Waterfield, M. D., and Emr, S. D. (1993). Phosphatidylinositol 3-kinase encoded by yeast VPS34 gene essential for protein sorting. Science 260, 88-91.
145. Sha, B., Phillips, S. E., Bankaitis, V. A., and Luo, M. (1997). Crystallization and preliminary X-ray diffraction studies of Saccharomyces cerevisiae phospholipid-transfer protein Sec14p. Acta Crystallogr D 53, 784-786.
146. Sha, B., Phillips, S. E., Bankaitis, V. A., and Luo, M. (1998). Crystal structure of the Saccharomyces cerevisiae phosphatidylinositol-transfer protein. Nature 391, 506-510.
147. Shiao, Y.-J., Balcerzak, B., and Vance, J. E. (1998). A mitochondrial membrane protein is required for translocation of phosphatidylserine from mitochondria-associated membranes to mitochondria. Biochem. J. 331, 217-223.
148. 1H- NMR studies of a wheat phospholipid transfer protein: Sequential resonance assignments and secondary structure. Biochemistry 30, 11600-11608.
149. Simon J. P., Morimoto, T., Bankaitis, V. A., Gottlieb, T. A., Ivanov, I. E., Adesnik, M., Sabatini, D. D. (1998). An essential role for the phosphatidylinositol transfer protein in the scission of coatomer-coated vesicles from the trans-Golgi network. Proc. Natl. Acad. Sci. U. S. A. 95, 11181-11186.
150. Skinner, H. B., Alb, J. G. Jr., Whitters, E. A., Helmkamp, G. M. Jr., and Bankaitis, V. A. (1993). Phospholipid transfer activity is relevant to but not sufficient for the essential function of the yeast SEC14 gene product. EMBO J. 12, 4775-4784.
151. Skinner, H. B., McGee, T. P., McMaster, C. R., Fry, M. R., Bell, R. M., and Bankaitis, V. A. (1995). The Saccharomyces cerevisiae phosphatidylinositol-transfer protein effects a ligand-dependent inhibition of choline-dependent phosphate cytidylyltransferase activity. Proc. Natl. Acad. Sci. USA 92, 112-116.
152. Sleight, R. G., and Pagano, R. E. (1983). Rapid appearance of newly synthesized phosphatidylethanolamine at the plasma membrane. J. Biol. Chem. 258, 9050-9058.
153. Snoek, G. T., Westerman J., Wouters, F. S., and Wirtz, K. W. A. (1993). Phosphorylation and redistribution of the phosphatidylinositol-transfer protein in phorbol 12-myristate 13 acetate- and bombesin-stimulated Swiss mouse 3T3 fibroblasts. Biochem. J. 291, 649-656.
154. Somerharju, P. J., van Paridon, P., and Wirtz, K. W. A. (1983). Phosphatidylinositol transfer protein from bovine brain. Substrate specificity and membrane binding properties. Biochim. Biophys. Acta 731, 186-195.
155. Somerharju, P. J., van Loon, D., and Wirtz, K. W. A. (1987). Determination of the acyl chain specificity of the bovine liver phosphatidylcholine transfer protein. Application of pyrene labeled phosphatidylcholine species. Biochemistry 26, 7193-7199.
156. Sreenivas, A., Patton-Vogt, J. L., Bruno, V., Griac, P. and Henry, S. A. (1998). A role for phospholipase D in growth, secretion, and regulation of membrane lipid synthesis in yeast. J. Biol. Chem. 273, 16635-16638.
157. Stamnes, M., Schiavo, G., Stenbeck, G., Sollner, T. and Rothman, J. E. (1998). ADP-ribosylation factor and phosphatidic acid levels in Golgi membranes during budding of coatomer- coated vesicles. Proc. Natl. Acad. Sci. USA 95, 13676-13680.
158. Stock, S. D., Hama, H., DeWald, D. B., and Takemoto, J. Y. (1999). SEC14-dependent secretion in Saccharomyces cerevisiae: Non-dependence on sphingolipid-coupled diacylglycerol synthesis. J. Biol. Chem. 274, 12979-12983.
159. Stolowich, N. J., Frolov, A., Atshaves, B., Murphy, E. J., Jolly, C. A., Billheimer, J. T., Scott, A. I., and Schroeder, F. (1997). The sterol carrier protein-2 fatty acid binding site: An NMR, circular dichroic, and fluorescence spectroscopic determination. Biochemistry 36, 1719-1729.
160. Szolderits, G., Hermetter, A., Paltauf, F., and Daum, G. (1989). Membrane properties modulate the activity of a phosphatidylinositol transfer protein from the yeast, Saccharomyces cerevisiae. Biochim. Biophys. Acta 986, 301-309.
161. Tall, A. (1995). Plasma lipid transfer proteins. Annu. Rev. Biochem. 64, 235-257.
162. Tanaka, S., and Hosaka, K. (1994). Cloning of a cDNA encoding a second phosphatidylinositol transfer protein from rat brain by complementation of the yeast sec14 mutation. J. Biochem. 115, 981-984.
163. Tanaka, S., Yamashita, S., and Hosaka, K. (1995). Cloning and expression of human cDNA encoding phosphatidylinositol transfer protein β.Biochim. Biophys. Acta 1259, 199-202.
164. Teerlink, T., Van der Krift, T. P., Post, M., and Wirtz, K. W. A. (1982). Tissue distribution and subcellular localization of phosphatidylcholine transfer protein in rats as determined by radioimmunoassay. Biochim. Biophys. Acta 713, 61-67.
165. Thomas, G. M. H., Cunningham, E., Fensome, A., Ball, A., Totty, N. F., Truong, O., Hsuan, J. J., and Cockcroft, S. (1993). An essential role for phosphatidylinositol transfer protein in phospholipase C-mediated inositol lipid signaling. Cell 74, 919-928.
166. Tremblay, J. M., Voziyan, P. A., Helmkamp, G. M. Jr., and Yarbrough, L. R. (1998). The C- terminus of phosphatidylinositol transfer protein modulates membrane interactions and transfer activity but not phospholipid binding. Biochim. Biophys. Acta 1389, 91-100.
167. Tsao, F. H. C., Cheng. W., Chen, X., Hu, J., and Chen, X. (1996). Isolation and sequencing of the cDNA encoding phosphatidylinositol transfer protein from rabbit lung. Gene 172, 299-302.
168. Tüscher, O., Lorra, C., Bouma, B., Wirtz, K. W. A., and Huttner, W. B. (1997). Cooperativity of phosphatidylinositol transfer protein and phospholipase D in secretory vesicle formation from the TGN - Phosphoinositides as a common denominator? FEBS Lett. 419, 271-275.
169. van Amerongen, A., Demel, R. A., Westerman, J., and Wirtz, K. W. A. (1989). Transfer of cholesterol and oxysterol derivatives by nsLTP (CSP2): A study on its mode of action. Biochim. Biophys. Acta 1004, 36-43.
170. Vance, J. E., Aaslman, E. J., and Szarka, R. (1991). Brefeldin A does not inhibit the movement of phosphatidylethanolamine from its site of synthesis to the cell surface. J. Biol. Chem. 266, 8241-8247.
171. van Golde, L. M. G., Oldenborg, V., Post, M., and Batenburg, J. J. (1980). Phospholipid transfer proteins in rat lung: Identification of a protein specific for phosphatidylglycerol. J. Biol. Chem. 255, 6011-6013.
172. van Heusden, G. P. H., Bos, K., and Wirtz, K. W. A. (1990). The occurrence of soluble and membrane-bound non-specific lipid transfer protein (sterol carrier protein 2) in rat tissues. Biochim. Biophys. Acta 1046, 315-321.
173. van Paridon, P. A., Gadella, T. W. J. Jr., Somerharju, P., and Wirtz, K. W. A. (1987a). On the relationship between the dual specificity of the bovine phosphatidylinositol transfer protein and membrane phosphatidylinositol levels. Biochim. Biophys. Acta 903, 68-77.
174. van Paridon, P. A., Visser, A. J. W. G., and Wirtz, K. W. A. (1987b). Binding of phospholipids to the phosphatidylinositol transfer protein from bovine brain as studied by steady-state and time-resolved fluorescence spectroscopy. Biochim. Biophys. Acta 898, 172-180.
175. van Paridon, P. A., Gadella, T. W. J., Somerharju, P. J., and Wirtz, K. W. A. (1988). Properties of the binding sites for the sn-1 and sn-2 acyl chains on the phosphatidylinositol transfer protein from bovine brain. Biochemistry 27, 6208-6214.
176. Venuti, S. E., and Helmkamp, G. M. Jr. (1988). Tissue distribution, purification, and characterization of rat phosphatidylinositol transfer protein. Biochim. Biophys. Acta 946, 119-128.
177. Verkade, P., and Simons, K. (1997). Lipid microdomains and membrane trafficking in mammalian cells. Histochem. Cell Biol. 108, 211-220.
178. Vignols, F., Lung, G., Pammi, S., Tremousaygue, D., Grellet, F., Kader, J. C., Puigdomenech, P., and Delseny, M. (1994). Characterization of a rice gene coding for a lipid transfer protein. Gene 142, 265-270.
179. Vihtelic, T. S., Hyde, D. R., and O'Tousa, J. E. (1991). Isolation and characterization of the Drosophila retinal degeneration B (rdgB) gene. Genetics 127, 761-768.
180. Vihtelic, T. S., Goebl, M., Milligan, S., O'Tousa, J. E., and Hyde, D. R. (1993). Localization of Drosophila retinal degeneration B, a membrane-associated phosphatidylinositol transfer protein. J. Cell Biol. 122, 1013-1022.
181. Vogel, A., Schwarzmann, G., and Sandhoff, K. (1991). Glycosphingolipid specificity of the human sulfatide activator protein. Eur. J. Biochem. 200, 591-597.
182. Watanabe, S., and Yamada, M. (1986). Purification and characterization of a non-specific transfer protein from germinated castor bean endosperms which transfers phospholipids and galactolipids. Biochim. Biophys. Acta 876, 116-123.
183. Westerman, J., De Vries, K. J., Somerharju, P., Timermans-Herejigers, J. L. P. M., Snoek, G. T., and Wirtz, K. W. A. (1995). A sphingomyelin transferring protein from chicken liver. J. Biol. Chem. 270, 14263-14266.
184. Wijkander, J., and Sunder, R. (1989). A phospholipase A2 hydrolyzing arachidonoyl-phospholipids in mouse peritoneal macrophages. FEBS Lett. 244, 51-56.
185. Wirtz, K. W. A. (1968). Exchange of phospholipids between liver mitochondria and microsomes in vitro. J. Biol. Chem. 243, 3596-3602.
186. Wirtz, K. W. A. (1982). Phospholipid transfer proteins, In "Lipid-Protein Interactions" (P. C. Jost and O. H. Griffith, Eds.), pp. 151-231. Wiley, New York.
187. Wirtz, K. W. A. (1991a). Phospholipid transfer proteins. Annu. Rev. Biochem. 60, 73-99.
188. Wirtz, K. W. A. (1991b). Phospholipid transfer proteins: From lipid monolayers to cells. Klin. Wochenschr. 69, 105-111.
189. Wirtz, K. W. A. (1997). Phospholipid transfer proteins revisited. Biochem. J. 324, 353-360.
190. Wirtz, K. W. A., and Gadella, T. W. J. Jr. (1990). Properties and modes of action of specific and non-specific phospholipid transfer proteins. Experientia 46, 592-599.
191. Wirtz, K. W. A., and Zilversmit, D. B. (1968). Exchange of phospholipids between liver mitochondria and microsomes in vitro. J. Biol. Chem. 243, 3596-3602.
192. Wirtz, K. W. A., Devaux, P. R., and Bienvenue, A. (1980). Phosphatidylcholine exchange protein catalyzes the net transfer of phosphatidylcholine to model membranes. Biochemistry 19, 3395-3399.
193. Wirtz, K. W., Wouters, F. S., Bastiaens, P. H., Wanders, R. J., Seedorf, U., and Jovin, T. M. (1997). The non-specific lipid transfer protein (sterol carrier protein 2) acts as a peroxisomal fatty acyl-CoA binding protein. Biochem. Soc. Trans. 26, 374-378.
194. Wong, M., Brown, R. E., Barenholz, Y., and Thompson, T. W. (1984). Glycolipid transfer protein from bovine brain. Biochemistry 23, 6498-6505.
195. Woodard, C. E., Alcorta, E., and Carlson, J. (1992). The rdgB gene of Drosophila: A link between vision and olfaction. J. Neurogenet. 8, 17-31.
196. Xie, Z., Fang, M., Rivas, M. P., Faulkner, A. J., Sternweis, P. C., Engebrecht, J., and Bankaitis, V. A. (1998). Phospholipase D activity is required for suppression of yeast phosphatidylinositol transfer protein defects. Proc. Natl. Acad. Sci. USA 95, 12346-12351.
197. Yamada, K., and Sasaki, T. (1982). Rat liver glycolipid transfer protein: A protein which facilitates the translocation of mono- and dihexosylceramide from donor to acceptor liposomes. J. Biol. Chem. 92, 457-464.
198. Yamada, K., and Sasaki, T. (1986). Glycolipid transfer protein from pig brain transfers glycolipids with β-linked sugars but not with α-linked sugars at the sugar-lipid linkage. Biochim. Biophys. Acta 879, 345-349.
199. Yamada, K., Abe, A., and Sasaki, T. (1985). Specificity of the glycolipid transfer protein from pig brain. J. Biol. Chem. 260, 4615-4621.
200. Zucker, C. S. (1996). The biology of vision in Drosophila. Proc. Natl. Acad. Sci. USA 93, 571-576.