The first 5 amino acids of the carboxyl terminus of phosphatidylinositol transfer protein (PITP) α play a critical role in inositol lipid signaling. Transfer activity of PITP is essential but not sufficient for restoration of phospholipase C signaling

Journal of Biological Chemistry

Volumn 272, Issue 23, 1997, Pages 14908-14913

  Hara, Shuntaro ^a   Swigart, Phil ^a   Jones, David ^a   Cockcroft, Shamshad ^a  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

GUANINE NUCLEOTIDE BINDING PROTEIN; INOSITOL; LIPID BINDING PROTEIN; MUTANT PROTEIN; PHOSPHATIDYLCHOLINE; PHOSPHATIDYLINOSITOL; PHOSPHOLIPASE C;

ARTICLE; CARBOXY TERMINAL SEQUENCE; CELL STRAIN HL 60; CONTROLLED STUDY; HUMAN; HUMAN CELL; LIPID TRANSPORT; PRIORITY JOURNAL; PROTEIN BINDING; SIGNAL TRANSDUCTION;

AMINO ACID SEQUENCE; CARRIER PROTEINS; CLONING, MOLECULAR; DNA PRIMERS; ESCHERICHIA COLI; GTP-BINDING PROTEINS; HUMANS; KINETICS; MEMBRANE PROTEINS; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; PHOSPHATIDIC ACIDS; PHOSPHATIDYLCHOLINES; PHOSPHATIDYLINOSITOLS; PHOSPHOLIPASE C; PHOSPHOLIPID TRANSFER PROTEINS; POINT MUTATION; POLYMERASE CHAIN REACTION; RECOMBINANT PROTEINS; SACCHAROMYCES CEREVISIAE PROTEINS; SEQUENCE DELETION; SIGNAL TRANSDUCTION;

EID: 0030914647     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.272.23.14908     Document Type: Article

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