The vein utilizes different sources of energy than the artery during pulmonary hypoxic vasoconstriction

Experimental Lung Research

Volumn 22, Issue 1, 1996, Pages 51-63

  Zhao, Ying ^a   Packer, C Subah ^a   Rhoades, Rodney A ^a  

^a INDIANA UNIVERSITY   (United States)

Author keywords

energetics; glycolysis; lactate; oxidative phosphorylation; pyruvate; vascular smooth muscle

Indexed keywords

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; GLYCOLYSIS; HYPOXIA; LUNG ARTERY; LUNG VEIN; MALE; NONHUMAN; OXIDATIVE PHOSPHORYLATION; PRIORITY JOURNAL; RAT; VASOCONSTRICTION;

EID: 0030061363     PISSN: 01902148     EISSN: None     Source Type: Journal    
DOI: 10.3109/01902149609074017     Document Type: Article

References (21)

1. Bennie RE, Packer CS, Powell DR, Jin N, Rhoades RA. Biphasic contractile response of pulmonary artery to hypoxia. Am J Physiol. 1991;261:L156-L163.
2. Jin N, Packer CS, Rhoades RA. Pulmonary arterial hypoxic contraction: signal transduction. Am J Physiol. 1992;263:L73-L78.
3. Zhao Y, Packer CS, Rhoades RA. The pulmonary vein contracts in response to hypoxia. Am J Physiol Lung Cell Mol Physiol. 1993;9:L89-L92.
4. Marshall C, Cooper DY, Marshall BE. Reduced availability of energy initiates pulmonary vasoconstriction. Proc Soc Exp Biol Med. 1988;187:282-286.
5. McMurtry IF, Rounds S, Stanbrook H. Studies of the mechanism of hypoxic pulmonary vasoconstriction. Adv Shock Res. 1982;8:21-33.
6. Ohe M, Mimata T, Haneda T, Takishima T. Time course of pulmonary vasoconstriction with repeated hypoxia and glucose depletion. Respir Physiol. 1986;63:177-186.
7. Rounds S, McMurtry IF. Inhibitors of oxidative ATP production cause transient vasoconstriction and block subsequent pressor responses in rat lungs. Circ Res. 1981;48:393-400.
8. Stanbrook HS, McMurtry IF. Inhibitors of glycolysis potentiate hypoxic vasoconstriction in rat. lungs. J Appl Physiol. 1983;55:1467-1473.
9. Souhrada JF, Dickey DW. Effect of substrate on hypoxic response of pulmonary artery. J Appl Physiol. 1976;40:533-538.
10. Buescher PC, Pearse DB, Pillai RP, Litt MC, Mitchell MC, Sylvester JT. Energy state and vasomotor tone in hypoxic pig lungs. J Appl Physiol. 1991;70:1874-1881.
11. Wiener CM, Sylvester JT. Effects of glucose on hypoxic vasoconstriction in isolated ferret lungs. J Appl Physiol. 1991;70:439-446.
12. Lynch RM, Kuettner CP, Paul RJ. Glycogen metabolism during tension generation and maintenance in vascular smooth muscle. Am J Physiol. 1989;257(Cell Physiol. 26):C736-C742.
13. Paul RJ. Smooth muscle energetics. Annu Rev Physiol. 1989;51:331-349.
14. Paul RJ, Bauer M, Pease W. Vascular smooth muscle: aerobic glycolysis linked to Na-K transport processes. Science. 1979;206:1414.
15. Williams B, Schrier RW. Effect of elevated extracellular glucose concentrations on calcium ion uptake by cultured rat vascular smooth muscle cells. Miner Electrolyte Metab. 1992;18:145-150.
16. Orton EC, Raffestin B, McMurtry IF. Protein kinase C influences rat pulmonary vascular reactivity. Am Rev Respir Dis. 1990;141:654-658.
17. Williams B, Tsai P, Schrier RW. Glucose-induced down-regulation of angiotensin II and arginine vasopressin receptors in cultured rat aortic vascular smooth muscle cells: role of protein kinase C. J Clin Invest. 1992;90:1992-1999.
18. Williams B, Schrier RW. Characterization of glucose-induced in situ protein kinase C activity in cultured vascular smooth muscle cells. Diabetes. 1992;41:1464-1472.
19. Bergofsky EH, Bass BG, Ferretti R, Fishman AP. Pulmonary vasoconstriction in response to precapillary hypoxemia. J Clin Invest. 1963;41:1201-1215.
20. Lloyd TC. Effect of alveolar hypoxia on pulmonary resistance. J Appl Physiol. 1964;19:1086-1094.
21. Lloyd TC. Pulmonary vasoconstriction during histotoxic hypoxia. J Appl Physiol. 1965;20:488-490.