Human isolated coronary artery contraction to sumatriptan characterised by the selective 5-HT(1B/1D) receptor antagonist GR55562

Pharmacology and Toxicology

Volumn 86, Issue 6, 2000, Pages 287-290

  MaassenVanDenBrink, Antoinette ^a   Reekers, Marije ^a   Bax, Willem A ^a   Saxena, Pramod R ^a  

^a ERASMUS MEDICAL CENTER   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

3 (3 DIMETHYLAMINOPROPYL) 4 HYDROXY N [4 (4 PYRIDINYL)PHENYL]BENZAMIDE; SEROTONIN 1B ANTAGONIST; SEROTONIN 1D ANTAGONIST; SUMATRIPTAN;

ADULT; ARTICLE; CLINICAL ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; CORONARY ARTERY CONSTRICTION; FEMALE; HUMAN; HUMAN TISSUE; MALE; PATHOGENESIS; PRIORITY JOURNAL; RECEPTOR AFFINITY;

BENZAMIDES; CORONARY VESSELS; DINOPROST; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG INTERACTIONS; HUMANS; MUSCLE CONTRACTION; MUSCLE, SMOOTH, VASCULAR; POTASSIUM; PYRIDINES; RECEPTOR, SEROTONIN, 5-HT1B; RECEPTORS, SEROTONIN; SEROTONIN; SEROTONIN ANTAGONISTS; SUBSTANCE P; SUMATRIPTAN; VASOCONSTRICTOR AGENTS;

EID: 0034048472     PISSN: 09019928     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.0901-9928.2000.860608.x     Document Type: Article

References (28)

1. 1 receptor subtype coupled to the inhibition of adenylate cyclase. Proc. Natl. Acad. Sci. USA, 1993, 90, 408-412.
2. 7) positively linked to adenylate cyclase. J. Biol. Chem. 1993, 268, 23422-23426.
3. Bax, W. A., G. J. Renzenbrink, D. van Heuven-Nolsen, H. J. M. Thijssen, E. Bos & P. R. Saxena: 5-HT receptors mediating contractions of the isolated human coronary artery. Eur. J. Pharmacol. 1993, 239, 203-210.
4. 1D-like receptors, and a comparison with grafted veins. Naunyn-Schmiedebergs Arch. Pharmacol. 1992, 345, 500-508.
5. Beer, M. S., M. A. Heald, G. McAllister & J. A. Stanton: Pharmacological characterisation of a cloned dog 5-HT1B receptor cell line. Eur. J. Pharmacol. 1998, 360, 117-121.
6. Castro, M. E., T. Romon, M. J. Castillo, E. del Olmo, A. Pazos & C. del Arco: Identification and characterization of a new serotonergic recognition site with high affinity for 5-carboxamidotryptamine in mammalian brain. J. Neurochem. 1997, 69, 2123-2131.
7. 1D receptor subtypes mediating cerebral vasoconstriction. Cephalalgia 1995, 15, 99.
8. 2 receptor activation. Eur. J. Pharmacol. 1989, 161, 91-94.
9. 1B/1D and novel receptors. Brit. J. Pharmacol. 1998, 123, 1561-1570.
10. Docherty, J. R.: Contractions to 5-hydroxytryptamine (5-HT) receptor agonists in the human saphenous vein. Brit. J. Pharmacol. 1990, 90, 107.
11. 1DB receptors. Circulation 1994, 90, 1141-1153.
12. Kelly, K. M.: Cardiac arrest following use of sumatriptan. Neurology 1995, 45, 1211-1213.
13. 3H]alniditan. Mol. Pharmacol. 1996, 50, 1567-1580.
14. Maassen Van Den Brink, A., W. A. Bax, M. D. Ferrari, F. J. Zijlstra, E. Bos & P. R. Saxena: Augmented contraction of the human isolated coronary artery by sumatriptan; a possible role for endogenous thromboxane. Brit. J. Pharmacol. 1996, 119, 855-862.
15. Maassen Van Den Brink, A., M. Reekers, W. A. Bax, M. D. Ferrari & P. R. Saxena: Coronary side-effect potential of current and prospective antimigraine drugs. Circulation 1998, 98, 25-30.
16. 1 agonist, on the systemic, pulmonary, and coronary circulation. Circulation 1993, 87, 401-405.
17. 1-like receptor-mediated vasoconstriction in human pulmonary artery. Brit. J. Pharmacol. 1996, 119, 277-282.
18. 1D receptors. Eur. J. Pharmacol. 1999, 368, 259-268.
19. Nilsson, T., J. Longmore, D. Shaw, E. Pantev, J. A. Bard, T. Branchek & L. Edvinsson: Characterisation of 5-HT receptors in human coronary arteries by molecular and pharmacological techniques. Eur. J. Pharmacol. 1999, 372, 49-56.
20. O'Connor, P. & P. Gladstone: Oral sumatriptan-associated transmural myocardial infarction. Neurology 1995, 45, 2274-2276.
21. Ottervanger, J. P., H. J. A. Paalman, G. L. Boxma & B. H. C. Stricker: Transmural myocardial infarction with sumatriptan. Lancet 1993, 341, 861-862.
22. 1F-receptor activation. Brit. J. Clin. Pharmacol. 1999, 47, 75-82.
23. Roon, K. I., A. Maassen Van Den Brink, M. D. Ferrari & P. R. Saxena: Bovine isolated middle cerebral artery contractions to antimigraine drugs. Naunyn Schmiedebergs Arch. Pharmacol. 1999, 360, 591-596.
24. Shen, Y., F. J. Monsma, Jr., M. A. Metcalf, P. A. Jose, M. W. Hamblin & D. R. Sibley: Molecular cloning and expression of a 5-hydroxytryptamine7 serotonin receptor subtype. J. Biol. Chem. 1993, 268, 18200-18204.
25. Steel, R. G. D. & J. H. Torrie: Principles and procedures of statistics. A biomedical approach, 2nd. ed. McGraw-Hill, Kogakusha Ltd., Tokyo, 1980.
26. 7 receptor subtype. Brit. J. Pharmacol. 1996, 118, 1421-1428.
27. Toda, N. & T. Okamura: Comparison of the response to 5-carboxamidotryptamine and serotonin in isolated human, monkey and dog coronary arteries. J. Pharmacol. Exp. Therap. 1990, 253, 676-682.
28. 1Dβ. Proc. Natl. Acad. Sci. USA 1992, 89, 3630-3634.