AIT-082, a cognitive enhancer, is transported into brain by a nonsaturable influx mechanism and out of brain by a saturable efflux mechanism

Journal of Pharmacology and Experimental Therapeutics

Volumn 293, Issue 3, 2000, Pages 813-821

  Taylor, Eve M ^a   Yan, Rongzi ^a   Hauptmann, Nils ^a   Maher, Timothy J ^a,b   Djahandideh, Daniela ^a   Glasky, Alvin J ^a  

^a NeoTherapeutics Inc   (United States)

^b MASSACHUSETTS COLLEGE OF PHARMACY AND HEALTH SCIENCES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

LETEPRINIM; NOOTROPIC AGENT; UNCLASSIFIED DRUG;

ACTIVE TRANSPORT; ADOLESCENT; AGED; ARTICLE; BLOOD BRAIN BARRIER; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG BRAIN LEVEL; DRUG CLEARANCE; DRUG HALF LIFE; DRUG PENETRATION; DRUG STRUCTURE; DRUG TRANSPORT; MALE; MICRODIALYSIS; MOUSE; NONHUMAN; PRIORITY JOURNAL; TRANSPORT KINETICS;

AGE FACTORS; AMINOBENZOIC ACIDS; ANIMALS; BIOLOGICAL TRANSPORT; BLOOD-BRAIN BARRIER; BRAIN; HYPOXANTHINES; MALE; MICE; MICE, INBRED C57BL; MICRODIALYSIS; NOOTROPIC AGENTS; PSYCHOTROPIC DRUGS; PURINES;

EID: 0034046971     PISSN: 00223565     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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