Localization of purine metabolizing enzymes in bovine brain microvessel endothelial cells: An enzymatic blood-brain barrier for dideoxynucleosides?

Pharmaceutical Research

Volumn 13, Issue 12, 1996, Pages 1881-1886

  Johnson, Mark D ^a   Andersen, Bradley D ^a  

^a UNIVERSITY OF UTAH   (United States)

Author keywords

2',3' dideoxynucleoside; Adenosine deaminase; Bovine brain endothelial cell; Cytidine deaminase; Enzymatic blood brain barrier; Purine nucleoside phosphorylase

Indexed keywords

2',3' DIDEOXY 2' FLUOROADENOSINE; 2',3' DIDEOXYADENOSINE; 2',3' DIDEOXYNUCLEOSIDE DERIVATIVE; 6 CHLORO 2',3' DIDEOXYPURINE; ADENOSINE DEAMINASE; ALKALINE PHOSPHATASE; CYTIDINE DEAMINASE; DIDANOSINE; INOSINE; PURINE NUCLEOSIDE PHOSPHORYLASE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BLOOD BRAIN BARRIER; BRAIN TISSUE; CATTLE; DRUG DEGRADATION; ENZYME ACTIVITY; ENZYME LOCALIZATION; ENZYME SPECIFICITY; ERYTHROCYTE; NONHUMAN; PRIORITY JOURNAL; VASCULAR ENDOTHELIUM;

ADENOSINE DEAMINASE; ANIMALS; BLOOD-BRAIN BARRIER; BRAIN; CATTLE; CEREBRAL CORTEX; CYTIDINE DEAMINASE; DIDEOXYNUCLEOSIDES; ENDOTHELIUM, VASCULAR; ERYTHROCYTES; PURINE-NUCLEOSIDE PHOSPHORYLASE; SPLEEN; SUBSTRATE SPECIFICITY;

EID: 0030457859     PISSN: 07248741     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1016001712524     Document Type: Article

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