-
1
-
-
0028353480
-
Second-line drug therapy for rheumatoid arthritis
-
Cash JM, Klippel JH. Second-line drug therapy for rheumatoid arthritis. N Engl J Med 1994;330:1368-75.
-
(1994)
N Engl J Med
, vol.330
, pp. 1368-1375
-
-
Cash, J.M.1
Klippel, J.H.2
-
2
-
-
0028147809
-
The optimal management of early rheumatoid disease: The key to preventing disability
-
Emery P. The optimal management of early rheumatoid disease: the key to preventing disability. Br J Rheumatol 1994;33:765-81.
-
(1994)
Br J Rheumatol
, vol.33
, pp. 765-781
-
-
Emery, P.1
-
3
-
-
0031934699
-
Trends in antirheumatic medication use among patients with rheumatoid arthritis, 1981-1996
-
Ward MM, Fries JF. Trends in antirheumatic medication use among patients with rheumatoid arthritis, 1981-1996. J Rheumatol 1998;25:408-16.
-
(1998)
J Rheumatol
, vol.25
, pp. 408-416
-
-
Ward, M.M.1
Fries, J.F.2
-
4
-
-
0025080342
-
Termination of slow acting antirheumatic therapy in rheumatoid arthritis: A 14-year prospective evaluation of 1017 consecutive starts
-
Wolfe F, Hawley DJ, Cathey MA. Termination of slow acting antirheumatic therapy in rheumatoid arthritis: a 14-year prospective evaluation of 1017 consecutive starts. J Rheumatol 1990;17:994-1002.
-
(1990)
J Rheumatol
, vol.17
, pp. 994-1002
-
-
Wolfe, F.1
Hawley, D.J.2
Cathey, M.A.3
-
5
-
-
0027077654
-
Longterm drug therapy for rheumatoid arthritis in seven rheumatology private practices: II. Second line drugs and prednisone
-
Pincus T, Marcum SB, Callahan LF. Longterm drug therapy for rheumatoid arthritis in seven rheumatology private practices: II. Second line drugs and prednisone. J Rheumatol 1992;19:1885-94.
-
(1992)
J Rheumatol
, vol.19
, pp. 1885-1894
-
-
Pincus, T.1
Marcum, S.B.2
Callahan, L.F.3
-
6
-
-
0030785828
-
Adverse drug reactions of DMARDs and DC-ARTs in rheumatoid arthritis
-
Wolfe F. Adverse drug reactions of DMARDs and DC-ARTs in rheumatoid arthritis. Clin Exp Rheumatol 1997;15(suppl. 17):75-81.
-
(1997)
Clin Exp Rheumatol
, vol.15
, Issue.17 SUPPL.
, pp. 75-81
-
-
Wolfe, F.1
-
7
-
-
0027238470
-
Effects of leflunomide on immune responses and models of inflammation
-
Bartlett RR, Anagnostopulos H, Zielinski T, Mattar T, Schleyerbach R. Effects of leflunomide on immune responses and models of inflammation. Springer Semin Immunopathol 1993;14:381-94.
-
(1993)
Springer Semin Immunopathol
, vol.14
, pp. 381-394
-
-
Bartlett, R.R.1
Anagnostopulos, H.2
Zielinski, T.3
Mattar, T.4
Schleyerbach, R.5
-
9
-
-
0004925117
-
Effects of leflunomide on early T cell signaling and cell cycle commitment
-
Herrmann M, Frangou CG, Kirschbaum B. Effects of leflunomide on early T cell signaling and cell cycle commitment. Rheumatol Eur 1997;26(suppl. 2):63.
-
(1997)
Rheumatol Eur
, vol.26
, Issue.2 SUPPL.
, pp. 63
-
-
Herrmann, M.1
Frangou, C.G.2
Kirschbaum, B.3
-
10
-
-
0031179645
-
The immunosuppressive metabolite of leflunomide, A77 1726, affects murine T cells through two biochemical mechanisms
-
Elder RT, Xu X, Williams JW, Gong H, Finnegan A, Chong ASF. The immunosuppressive metabolite of leflunomide, A77 1726, affects murine T cells through two biochemical mechanisms. J Immunol 1997;159:22-7.
-
(1997)
J Immunol
, vol.159
, pp. 22-27
-
-
Elder, R.T.1
Xu, X.2
Williams, J.W.3
Gong, H.4
Finnegan, A.5
Chong, A.S.F.6
-
11
-
-
0031865023
-
Mechanism of action of leflunomide in rheumatoid arthritis
-
Fox RI. Mechanism of action of leflunomide in rheumatoid arthritis. J Rheumatol 1998;25(suppl. 53):20-6.
-
(1998)
J Rheumatol
, vol.25
, Issue.53 SUPPL.
, pp. 20-26
-
-
Fox, R.I.1
-
12
-
-
0033557695
-
Immunosuppressive leflunomide metabolite (A77 1726) blocks TNF-dependent nuclear factor-κB activation and gene expression
-
Manna SK, Aggarwal BB. Immunosuppressive leflunomide metabolite (A77 1726) blocks TNF-dependent nuclear factor-κB activation and gene expression. J Immunol 1999;162:2095-102.
-
(1999)
J Immunol
, vol.162
, pp. 2095-2102
-
-
Manna, S.K.1
Aggarwal, B.B.2
-
13
-
-
0030970556
-
The role of T cells in the immunopathogenesis of rheumatoid arthritis: New perspectives
-
Fox DA. The role of T cells in the immunopathogenesis of rheumatoid arthritis: new perspectives. Arthritis Rheum 1997;40:598-609.
-
(1997)
Arthritis Rheum
, vol.40
, pp. 598-609
-
-
Fox, D.A.1
-
14
-
-
0032112641
-
New insights in the pathogenesis of rheumatoid arthritis
-
Breedveld FC. New insights in the pathogenesis of rheumatoid arthritis. J Rheumatol 1998;25(suppl. 53):3-7.
-
(1998)
J Rheumatol
, vol.25
, Issue.53 SUPPL.
, pp. 3-7
-
-
Breedveld, F.C.1
-
15
-
-
0030021790
-
The role of T-lymphocytes and cytokines in rheumatoid arthritis
-
Smolen JS, Tohidast-Akrad M, Gal A et al. The role of T-lymphocytes and cytokines in rheumatoid arthritis. Scand J Rheumatol 1996;25:1-4.
-
(1996)
Scand J Rheumatol
, vol.25
, pp. 1-4
-
-
Smolen, J.S.1
Tohidast-Akrad, M.2
Gal, A.3
-
17
-
-
0032703306
-
Cytokine production by synovial T cells in rheumatoid arthritis
-
Steiner G, Tohidast-Akrad M, Witzmann G et al. Cytokine production by synovial T cells in rheumatoid arthritis. Rheumatology 1999;38:202-13.
-
(1999)
Rheumatology
, vol.38
, pp. 202-213
-
-
Steiner, G.1
Tohidast-Akrad, M.2
Witzmann, G.3
-
18
-
-
0023945481
-
The American Rheumatism Association 1987 revised criteria for the classification of rheumatoid arthritis
-
Arnett FC, Edworthy SM, Bloch DA et al. The American Rheumatism Association 1987 revised criteria for the classification of rheumatoid arthritis. Arthritis Rheum 1988;31:315-24.
-
(1988)
Arthritis Rheum
, vol.31
, pp. 315-324
-
-
Arnett, F.C.1
Edworthy, S.M.2
Bloch, D.A.3
-
19
-
-
0024348027
-
A simplified twenty-eight-joint quantitative articular index in rheumatoid arthritis
-
Fuchs HA, Brooks RH, Callahan LF, Pincus T. A simplified twenty-eight-joint quantitative articular index in rheumatoid arthritis. Arthritis Rheum 1989;32:531-7.
-
(1989)
Arthritis Rheum
, vol.32
, pp. 531-537
-
-
Fuchs, H.A.1
Brooks, R.H.2
Callahan, L.F.3
Pincus, T.4
-
20
-
-
0028813226
-
Validity and reliability of the twenty-eight-joint count for the assessment of rheumatoid arthritis activity
-
Smolen JS, Breedveld FC, Eberl G et al. Validity and reliability of the twenty-eight-joint count for the assessment of rheumatoid arthritis activity. Arthritis Rheum 1995;38: 38-43.
-
(1995)
Arthritis Rheum
, vol.38
, pp. 38-43
-
-
Smolen, J.S.1
Breedveld, F.C.2
Eberl, G.3
-
21
-
-
0029044362
-
The American College of Rheumatology. Preliminary definition of improvement in rheumatoid arthritis
-
Felson DT, Anderson JJ, Boers M et al. The American College of Rheumatology. Preliminary definition of improvement in rheumatoid arthritis. Arthritis Rheum 1995;38:727-35.
-
(1995)
Arthritis Rheum
, vol.38
, pp. 727-735
-
-
Felson, D.T.1
Anderson, J.J.2
Boers, M.3
-
22
-
-
0033020292
-
Validity of area-under-the-curve analysis to summarize effect in rheumatoid arthritis clinical trials
-
Pham B, Cranney A, Boers M, Verhoeven AC, Wells G, Tugwell P. Validity of area-under-the-curve analysis to summarize effect in rheumatoid arthritis clinical trials. J Rheumatol 1999;26:712-6.
-
(1999)
J Rheumatol
, vol.26
, pp. 712-716
-
-
Pham, B.1
Cranney, A.2
Boers, M.3
Verhoeven, A.C.4
Wells, G.5
Tugwell, P.6
-
23
-
-
0015151774
-
Methods of scoring the progression of radiologic changes in rheumatoid arthritis
-
Sharp JT, Lidsky MD, Collins LC, Moreland J. Methods of scoring the progression of radiologic changes in rheumatoid arthritis. Arthritis Rheum 1971;14:706-20.
-
(1971)
Arthritis Rheum
, vol.14
, pp. 706-720
-
-
Sharp, J.T.1
Lidsky, M.D.2
Collins, L.C.3
Moreland, J.4
-
24
-
-
0033053835
-
Efficacy and safety of leflunomide compared with placebo and sulphasalazine in active rheumatoid arthritis: A double-blind, randomised, multicentre trial
-
Smolen JS, Kalden JR, Scott DL et al. Efficacy and safety of leflunomide compared with placebo and sulphasalazine in active rheumatoid arthritis: a double-blind, randomised, multicentre trial. Lancet 1999;353:259-66.
-
(1999)
Lancet
, vol.353
, pp. 259-266
-
-
Smolen, J.S.1
Kalden, J.R.2
Scott, D.L.3
-
25
-
-
0033596065
-
Treatment of active rheumatoid arthritis with leflunomide compared with placebo and methotrexate
-
Strand V, Cohen S, Schiff M, et al. Treatment of active rheumatoid arthritis with leflunomide compared with placebo and methotrexate. Arch Intern Med 1999;159: 2542-50.
-
(1999)
Arch Intern Med
, vol.159
, pp. 2542-2550
-
-
Strand, V.1
Cohen, S.2
Schiff, M.3
-
26
-
-
6744262231
-
A comparison of the efficacy and safety of leflunomide and methotrexate in the treatment of rheumatoid arthritis
-
in press
-
Emery P, Breedveld FC, Lemmel EM et al. A comparison of the efficacy and safety of leflunomide and methotrexate in the treatment of rheumatoid arthritis. Rheumatology 2000;39:in press.
-
(2000)
Rheumatology
, vol.39
-
-
Emery, P.1
Breedveld, F.C.2
Lemmel, E.M.3
-
27
-
-
6744238078
-
A phase III, randomized, double-blind study of leflunomide versus methotrexate in rheumatoid arthritis
-
Abstract no. 399
-
Emery P, Breedveld FC, Lemmel EM, Rosenberg R, Loew-Friedrich I. A phase III, randomized, double-blind study of leflunomide versus methotrexate in rheumatoid arthritis. Presented at the XIV EULAR Congress 1999; 103 Abstract no. 399.
-
(1999)
XIV EULAR Congress
, vol.103
-
-
Emery, P.1
Breedveld, F.C.2
Lemmel, E.M.3
Rosenberg, R.4
Loew-Friedrich, I.5
-
28
-
-
0025266158
-
Analysis of improvement in individual rheumatoid arthritis patients treated with disease-modifying anti-rheumatic drugs, based on the findings in patients treated with placebo
-
Paulus HE, Egger MJ, Ward JR, Williams JH and the Cooperative Systemic Studies of Rheumatic Diseases Group. Analysis of improvement in individual rheumatoid arthritis patients treated with disease-modifying anti-rheumatic drugs, based on the findings in patients treated with placebo. Arthritis Rheum 1990;33:477-84.
-
(1990)
Arthritis Rheum
, vol.33
, pp. 477-484
-
-
Paulus, H.E.1
Egger, M.J.2
Ward, J.R.3
Williams, J.H.4
-
29
-
-
0002852640
-
Retardation of structural damage with leflunomide in rheumatoid arthritis assessed by Larsen Methodology: 2-year results
-
Larsen A, Kalden JR, Scott DL et al. Retardation of structural damage with leflunomide in rheumatoid arthritis assessed by Larsen Methodology: 2-year results. Arthritis Rheum 1999;42(suppl. 9):S82.
-
(1999)
Arthritis Rheum
, vol.42
, Issue.9 SUPPL.
-
-
Larsen, A.1
Kalden, J.R.2
Scott, D.L.3
-
31
-
-
0027987025
-
Radiologic evidence of disease modification in rheumatoid arthritis patients treated with cyclosporine. Results of a 48-week multicenter study comparing low-dose cyclosporine with placebo. Norwegian Arthritis Study Group
-
Forre Ø, Norwegian Arthritis Study Group. Radiologic evidence of disease modification in rheumatoid arthritis patients treated with cyclosporine. Results of a 48-week multicenter study comparing low-dose cyclosporine with placebo. Norwegian Arthritis Study Group. Arthritis Rheum 1994;37:1506-12.
-
(1994)
Arthritis Rheum
, vol.37
, pp. 1506-1512
-
-
Forre, Ø.1
-
32
-
-
17444394445
-
Treatment of rheumatoid arthritis with recombinant human IL-1 receptor antagonist
-
Bresnihan B, Alvaro-Gracia JM, Cobby M et al. Treatment of rheumatoid arthritis with recombinant human IL-1 receptor antagonist. Arthritis Rheum 1998;41:2196-204.
-
(1998)
Arthritis Rheum
, vol.41
, pp. 2196-2204
-
-
Bresnihan, B.1
Alvaro-Gracia, J.M.2
Cobby, M.3
-
33
-
-
0028593942
-
Supplementation with folic acid during methotrexate therapy for rheumatoid arthritis. A double-blind, placebo-controlled trial
-
Morgan SL, Baggott JE, Vaughn, WH et al. Supplementation with folic acid during methotrexate therapy for rheumatoid arthritis. A double-blind, placebo-controlled trial. Ann Intern Med 1994;121:833-41.
-
(1994)
Ann Intern Med
, vol.121
, pp. 833-841
-
-
Morgan, S.L.1
Baggott, J.E.2
Vaughn, W.H.3
-
34
-
-
0031985832
-
The efficacy of folic acid and folinic acid in reducing methotrexate gastrointestinal toxicity in rheumatoid arthritis. A metaanalysis of randomized controlled trials
-
Ortiz Z, Shea B, Suarez-Almazor ME, Moher D, Wells GA, Tugwell P. The efficacy of folic acid and folinic acid in reducing methotrexate gastrointestinal toxicity in rheumatoid arthritis. A metaanalysis of randomized controlled trials. J Rheumatol 1998;1:36-43.
-
(1998)
J Rheumatol
, vol.1
, pp. 36-43
-
-
Ortiz, Z.1
Shea, B.2
Suarez-Almazor, M.E.3
Moher, D.4
Wells, G.A.5
Tugwell, P.6
-
35
-
-
0000082312
-
Effect of folic and folinic acid supplementation on toxicity and efficacy of methotrexate in rheumatoid arthritis: A randomized, double-blind, 48-week, clinical trial
-
Van Ede A, Laan R, Rood M et al. Effect of folic and folinic acid supplementation on toxicity and efficacy of methotrexate in rheumatoid arthritis: a randomized, double-blind, 48-week, clinical trial. Arthritis Rheum 1999;42(suppl. 9):S380.
-
(1999)
Arthritis Rheum
, vol.42
, Issue.9 SUPPL.
-
-
Van Ede, A.1
Laan, R.2
Rood, M.3
-
36
-
-
0008542121
-
Leflunomide vs sulfasalazine in rheumatoid arthritis: 24-month update of a randomized, double-blind study
-
Kalden JR, Schattenkircher M, Smolen JS et al. Leflunomide vs sulfasalazine in rheumatoid arthritis: 24-month update of a randomized, double-blind study. Arthritis Rheum 1999;42(suppl. 9):S271.
-
(1999)
Arthritis Rheum
, vol.42
, Issue.9 SUPPL.
-
-
Kalden, J.R.1
Schattenkircher, M.2
Smolen, J.S.3
-
37
-
-
0000052606
-
Two-year treatment of active rheumatoid arthritis (RA) with leflunomide (LEF) compared with placebo (PL) or methotrexate (MTX)
-
Cohen S, Weaver A, Schiff V for the Leflunomide Study Group. Two-year treatment of active rheumatoid arthritis (RA) with leflunomide (LEF) compared with placebo (PL) or methotrexate (MTX). Arthritis Rheum 1999; 42(suppl. 9):S271.
-
(1999)
Arthritis Rheum
, vol.42
, Issue.9 SUPPL.
-
-
Cohen, S.1
Weaver, A.2
Schiff, V.3
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