메뉴 건너뛰기




Volumn 7, Issue 4, 2000, Pages 545-556

Modulation of drug cytotoxicity by reintroduction of wild-type p53 gene (ad5CMV-p53) in human pancreatic cancer

Author keywords

Adenovirus; Apoptosis; Chemotherapy; p53; Pancreatic cancer

Indexed keywords

CISPLATIN; GEMCITABINE; PROTEIN P53;

EID: 0034039072     PISSN: 09291903     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.cgt.7700150     Document Type: Article
Times cited : (40)

References (45)
  • 2
    • 0029040131 scopus 로고
    • No standard treatment is available for advanced pancreatic cancer
    • Lionetto R, Pugliese V, Bruzzi P, Rosso R. No standard treatment is available for advanced pancreatic cancer. Eur J Cancer. 1995;31A:882-887.
    • (1995) Eur J Cancer. , vol.31 A , pp. 882-887
    • Lionetto, R.1    Pugliese, V.2    Bruzzi, P.3    Rosso, R.4
  • 3
    • 0031025998 scopus 로고    scopus 로고
    • Gene therapy for cancer: What have we done and where are we going?
    • Roth JA, Cristiano RJ. Gene therapy for cancer: what have we done and where are we going? J Natl Cancer Inst. 1997;89:21-39.
    • (1997) J Natl Cancer Inst. , vol.89 , pp. 21-39
    • Roth, J.A.1    Cristiano, R.J.2
  • 5
    • 0029011805 scopus 로고
    • Cell cycle and apoptosis: Common pathways to life and death
    • King KL, Cidlowski JA. Cell cycle and apoptosis: common pathways to life and death. J Cell Biochem. 1995;8:175-185.
    • (1995) J Cell Biochem. , vol.8 , pp. 175-185
    • King, K.L.1    Cidlowski, J.A.2
  • 6
    • 0031828248 scopus 로고    scopus 로고
    • Cell death and cancer: Replacement of apoptotic genes and inactivation of death suppressor genes in therapy
    • Favrot M, Coll JL, Louis N, Negoescu A. Cell death and cancer: replacement of apoptotic genes and inactivation of death suppressor genes in therapy. Gene Ther. 1998;5:728-739.
    • (1998) Gene Ther. , vol.5 , pp. 728-739
    • Favrot, M.1    Coll, J.L.2    Louis, N.3    Negoescu, A.4
  • 7
    • 0027451668 scopus 로고
    • p53-dependent apoptosis modulates the cytotoxicity of anticancer drugs
    • Lowe SC, Ruley HE, Jacks T, Housman DE. p53-dependent apoptosis modulates the cytotoxicity of anticancer drugs. Cell. 1993;74:957-967.
    • (1993) Cell , vol.74 , pp. 957-967
    • Lowe, S.C.1    Ruley, H.E.2    Jacks, T.3    Housman, D.E.4
  • 9
    • 0029972806 scopus 로고    scopus 로고
    • p53: Puzzle and paradigm
    • Ko LJ, Prives C. p53: puzzle and paradigm. Genes Dev. 1996;10:1054-1072.
    • (1996) Genes Dev. , vol.10 , pp. 1054-1072
    • Ko, L.J.1    Prives, C.2
  • 11
    • 0027109075 scopus 로고
    • p53, guardian of the genome
    • Lane DP. p53, guardian of the genome. Nature. 1992;358: 15-16.
    • (1992) Nature , vol.358 , pp. 15-16
    • Lane, D.P.1
  • 12
    • 0027359827 scopus 로고
    • WAF1, a potential mediator of p53 tumor suppression
    • El-Deiry WS, Tokino K, Velculescu VE, et al. WAF1, a potential mediator of p53 tumor suppression. Cell. 1993; 75:817-825.
    • (1993) Cell , vol.75 , pp. 817-825
    • El-Deiry, W.S.1    Tokino, K.2    Velculescu, V.E.3
  • 17
    • 0031029576 scopus 로고    scopus 로고
    • 2 to M transition: Implications for gene therapy
    • 2 to M transition: implications for gene therapy. Cancer Res. 1997;57:818-823.
    • (1997) Cancer Res. , vol.57 , pp. 818-823
    • Skladanowski, A.1    Larsen, A.K.2
  • 19
    • 0030094571 scopus 로고    scopus 로고
    • p53 and chemosensitivity
    • Wu S, El-Deiry WS. p53 and chemosensitivity. Nat Med. 1996;2:255-256.
    • (1996) Nat Med. , vol.2 , pp. 255-256
    • Wu, S.1    El-Deiry, W.S.2
  • 20
    • 0027944206 scopus 로고
    • P53 status and the efficacy of cancer therapy in vivo
    • Lowe SW, Bodis S, McClatchey A, et al. P53 status and the efficacy of cancer therapy in vivo. Science. 1994;266:807-810.
    • (1994) Science , vol.266 , pp. 807-810
    • Lowe, S.W.1    Bodis, S.2    McClatchey, A.3
  • 21
    • 0030021996 scopus 로고    scopus 로고
    • Inactivation of p53 enhances sensitivity to multiple chemotherapeutic agents
    • Hawkins DS, Demers GW, Galloway DA. Inactivation of p53 enhances sensitivity to multiple chemotherapeutic agents. Cancer Res. 1996;56:892-898.
    • (1996) Cancer Res. , vol.56 , pp. 892-898
    • Hawkins, D.S.1    Demers, G.W.2    Galloway, D.A.3
  • 23
    • 0029261994 scopus 로고
    • Apoptosis induced in human osteosarcoma cells is one of the mechanisms for the cytocidal effect of Ad5CMV-p53
    • Wang J, Bucana CD, Roth JA, Zhang WW. Apoptosis induced in human osteosarcoma cells is one of the mechanisms for the cytocidal effect of Ad5CMV-p53. Cancer Gene Ther. 1995;2:9-17.
    • (1995) Cancer Gene Ther. , vol.2 , pp. 9-17
    • Wang, J.1    Bucana, C.D.2    Roth, J.A.3    Zhang, W.W.4
  • 24
    • 0030020689 scopus 로고    scopus 로고
    • Adenovirus-mediated transfer of the p53 gene produces rapid and generalized death of human glioma cells via apoptosis
    • Gómez-Manzano C, Fueyo J, Kyritsis P, et al. Adenovirus-mediated transfer of the p53 gene produces rapid and generalized death of human glioma cells via apoptosis. Cancer Res. 1996;56:694-699.
    • (1996) Cancer Res. , vol.56 , pp. 694-699
    • Gómez-Manzano, C.1    Fueyo, J.2    Kyritsis, P.3
  • 25
    • 0030696171 scopus 로고    scopus 로고
    • 1 arrest and induces apoptosis in human cancer cells
    • 1 arrest and induces apoptosis in human cancer cells. Oncogene. 1997;5:1903-1909.
    • (1997) Oncogene , vol.5 , pp. 1903-1909
    • Kagawa, S.1    Fujiwara, T.2    Hizuta, A.3
  • 26
    • 0029893662 scopus 로고    scopus 로고
    • Adenovirus-mediated transfer of a wild-type p53 gene and induction of apoptosis in cervical cancer
    • Hamada K, Alemany R, Zhang WW, et al. Adenovirus-mediated transfer of a wild-type p53 gene and induction of apoptosis in cervical cancer. Cancer Res. 1996;56:3047-3054.
    • (1996) Cancer Res. , vol.56 , pp. 3047-3054
    • Hamada, K.1    Alemany, R.2    Zhang, W.W.3
  • 27
    • 0029017333 scopus 로고
    • Apoptosis induction mediated by wild-type p53 adenoviral gene transfer in squamous cell carcinoma of the head and neck
    • Liu TJ, El-Naggar K, McDonnell TJ, et al. Apoptosis induction mediated by wild-type p53 adenoviral gene transfer in squamous cell carcinoma of the head and neck. Cancer Res. 1995;55:3117-3122.
    • (1995) Cancer Res. , vol.55 , pp. 3117-3122
    • Liu, T.J.1    El-Naggar, K.2    McDonnell, T.J.3
  • 28
    • 0029856928 scopus 로고    scopus 로고
    • Wild-type p53 demonstrates functional dominance in a human colon carcinoma cell line in which it induces reversible growth arrest
    • Yang C, Stambrook PJ, Markowitz SD. Wild-type p53 demonstrates functional dominance in a human colon carcinoma cell line in which it induces reversible growth arrest. Clin Cancer Res. 1996;2:1639-1647.
    • (1996) Clin Cancer Res. , vol.2 , pp. 1639-1647
    • Yang, C.1    Stambrook, P.J.2    Markowitz, S.D.3
  • 30
    • 0001642806 scopus 로고    scopus 로고
    • Tissue-specific growth suppression and chemosensitivity promotion in human hepatocellular carcinoma cells by retroviral-mediated transfer of the wild-type p53 gene
    • Xu GW, Sun ZT, Forrester K, Wang XW, Coursen J, Harris CC. Tissue-specific growth suppression and chemosensitivity promotion in human hepatocellular carcinoma cells by retroviral-mediated transfer of the wild-type p53 gene. Hepatology. 1996;24:1264-1268.
    • (1996) Hepatology , vol.24 , pp. 1264-1268
    • Xu, G.W.1    Sun, Z.T.2    Forrester, K.3    Wang, X.W.4    Coursen, J.5    Harris, C.C.6
  • 31
    • 0029555339 scopus 로고
    • Use of wild-type p53 to achieve complete treatment sensitization of tumor cells expressing endogenous mutant p53
    • Gjerset RA, Turla ST, Sobol RE, et al. Use of wild-type p53 to achieve complete treatment sensitization of tumor cells expressing endogenous mutant p53. Mol Carcinog. 1995;14:275-285.
    • (1995) Mol Carcinog. , vol.14 , pp. 275-285
    • Gjerset, R.A.1    Turla, S.T.2    Sobol, R.E.3
  • 32
    • 0028939453 scopus 로고
    • Wild-type p53 stimulates expression from the human multidrug resistance promoter in a p53-negative cell line
    • Goldsmith ME, Gudas JM, Schneider E, Cowan KH. Wild-type p53 stimulates expression from the human multidrug resistance promoter in a p53-negative cell line. J Biol Chem. 1995;270:1894-1898.
    • (1995) J Biol Chem. , vol.270 , pp. 1894-1898
    • Goldsmith, M.E.1    Gudas, J.M.2    Schneider, E.3    Cowan, K.H.4
  • 33
    • 0030974567 scopus 로고    scopus 로고
    • Inability to induce the alteration of p53-null human pancreatic carcinoma cells after the transduction of wild-type p53 gene
    • Kimura M, Tagawa M, Takenaga K, et al. Inability to induce the alteration of p53-null human pancreatic carcinoma cells after the transduction of wild-type p53 gene. Anticancer Res. 1997;17:879-884.
    • (1997) Anticancer Res. , vol.17 , pp. 879-884
    • Kimura, M.1    Tagawa, M.2    Takenaga, K.3
  • 34
    • 0032568329 scopus 로고    scopus 로고
    • Stable reintroduction of wild-type p53 (MTmp53ts) causes the induction of apoptosis and neuroendocrine-like differentiation in human ductal pancreatic carcinoma cells
    • Lang D, Miknyoczki SJ, Huang L, Ruggeri BA. Stable reintroduction of wild-type p53 (MTmp53ts) causes the induction of apoptosis and neuroendocrine-like differentiation in human ductal pancreatic carcinoma cells. Oncogene. 1998;16:1593-1602.
    • (1998) Oncogene , vol.16 , pp. 1593-1602
    • Lang, D.1    Miknyoczki, S.J.2    Huang, L.3    Ruggeri, B.A.4
  • 35
    • 0033190986 scopus 로고    scopus 로고
    • Genetic background determines the response to adenovirus-mediated wild-type p53 expression in pancreatic tumor cells
    • Cascalló M, Mercadé E, Lluís F, et al. Genetic background determines the response to adenovirus-mediated wild-type p53 expression in pancreatic tumor cells. Cancer Gene Ther. 1999;6:428-436.
    • (1999) Cancer Gene Ther. , vol.6 , pp. 428-436
    • Cascalló, M.1    Mercadé, E.2    Lluís, F.3
  • 36
    • 7844240481 scopus 로고    scopus 로고
    • Disruption of the antiproliferative TGF-β signaling pathways in human pancreatic cells
    • Villanueva A, García C, Paules AB, et al. Disruption of the antiproliferative TGF-β signaling pathways in human pancreatic cells Oncogene. 1998;17:1969-1978.
    • (1998) Oncogene , vol.17 , pp. 1969-1978
    • Villanueva, A.1    García, C.2    Paules, A.B.3
  • 38
    • 0030830719 scopus 로고    scopus 로고
    • Mechanism of apoptosis induced by cisplatin and VP-16 in PANC-1 cells
    • Lee JU, Hosotani R, Wada M, et al. Mechanism of apoptosis induced by cisplatin and VP-16 in PANC-1 cells. Anticancer Res. 1997;17:3445-3450.
    • (1997) Anticancer Res. , vol.17 , pp. 3445-3450
    • Lee, J.U.1    Hosotani, R.2    Wada, M.3
  • 39
    • 0029845760 scopus 로고    scopus 로고
    • Structure and function of the p53 tumor suppressor gene: Clues for rational cancer therapeutic strategies
    • Harris CC. Structure and function of the p53 tumor suppressor gene: clues for rational cancer therapeutic strategies. J Natl Cancer Inst. 1996;88:1442-1455.
    • (1996) J Natl Cancer Inst. , vol.88 , pp. 1442-1455
    • Harris, C.C.1
  • 40
    • 0032771442 scopus 로고    scopus 로고
    • New agents in gastrointestinal malignancies: Part 2: GEMCITABINE in clinical practice
    • Stucky-Marshall L. New agents in gastrointestinal malignancies: Part 2: GEMCITABINE in clinical practice. Cancer Nurs. 1999; 22:290-296.
    • (1999) Cancer Nurs. , vol.22 , pp. 290-296
    • Stucky-Marshall, L.1
  • 41
    • 0027769876 scopus 로고
    • A new regulatory motif in cell-cycle control causing specific inhibition of cyclin D/CDK4
    • Serrano M, Hannon GJ, Beach D. A new regulatory motif in cell-cycle control causing specific inhibition of cyclin D/CDK4. Nature. 1993;366:704-707.
    • (1993) Nature , vol.366 , pp. 704-707
    • Serrano, M.1    Hannon, G.J.2    Beach, D.3
  • 42
    • 0028883179 scopus 로고
    • Tumor suppressor p53 is a direct transcriptional activator of the human bax gene
    • Miyashita T, Reed JC. Tumor suppressor p53 is a direct transcriptional activator of the human bax gene. Cell. 1995;80:293-299.
    • (1995) Cell , vol.80 , pp. 293-299
    • Miyashita, T.1    Reed, J.C.2
  • 43
    • 0031038137 scopus 로고    scopus 로고
    • Bax suppresses tumorigenesis and stimulates apoptosis in vivo
    • Yin C, Knudson CM, Korsmeyer SJ, van Dyke T. Bax suppresses tumorigenesis and stimulates apoptosis in vivo. Nature. 1997;385:637-640.
    • (1997) Nature , vol.385 , pp. 637-640
    • Yin, C.1    Knudson, C.M.2    Korsmeyer, S.J.3    Van Dyke, T.4
  • 44
    • 0028231586 scopus 로고
    • Induction of chemosensitivity in human lung cancer cells in vivo by adenovirus-mediated transfer of the wild-type p53 gene
    • Fujiwara T, Grimm EA, Mukhoadhyay T, Zhang WW, Owe-Schaub B, Roth JA. Induction of chemosensitivity in human lung cancer cells in vivo by adenovirus-mediated transfer of the wild-type p53 gene. Cancer Res. 1994;54: 2287-2291.
    • (1994) Cancer Res. , vol.54 , pp. 2287-2291
    • Fujiwara, T.1    Grimm, E.A.2    Mukhoadhyay, T.3    Zhang, W.W.4    Owe-Schaub, B.5    Roth, J.A.6
  • 45
    • 0029835487 scopus 로고    scopus 로고
    • Gene therapy for lung cancer: Enhancement of tumor suppression by a combination of sequential systemic cisplatin and adenovirus-mediated p53 gene transfer
    • Nguyen DM, Spitz FR, Yen N, Cristiano RJ, Roth JA. Gene therapy for lung cancer: enhancement of tumor suppression by a combination of sequential systemic cisplatin and adenovirus-mediated p53 gene transfer. J Thorac Cardiovasc Surg. 1996;112:1372-1376.
    • (1996) J Thorac Cardiovasc Surg. , vol.112 , pp. 1372-1376
    • Nguyen, D.M.1    Spitz, F.R.2    Yen, N.3    Cristiano, R.J.4    Roth, J.A.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.