Transforming growth factor but not and is critical for early rat lung branching

Developmental Dynamics

Volumn 217, Issue 4, 2000, Pages 343-360

  Liu, Jason ^a   Tseu, Irene ^a   Wang, Jinxia ^a   Tanswell, Keith ^a   Post, Martin ^a,b,c  

^a HOSPITAL FOR SICK CHILDREN RESEARCH INSTITUTE   (Canada)

^b UNIVERSITY OF TORONTO   (Canada)

^c HOSPITAL FOR SICK CHILDREN   (Canada)

Author keywords

Activin; Branching; Extracellular matrix; Proliferation; Rat lung; TGF ; TGF receptors

Indexed keywords

ACTIVIN; ACTIVIN RECEPTOR; TRANSFORMING GROWTH FACTOR BETA RECEPTOR; TRANSFORMING GROWTH FACTOR BETA1; TRANSFORMING GROWTH FACTOR BETA2; TRANSFORMING GROWTH FACTOR BETA3;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; EMBRYO; EMBRYO DEVELOPMENT; EMBRYO PATTERN FORMATION; EPITHELIUM CELL; EXPLANT; EXTRACELLULAR MATRIX; FETUS; LUNG DEVELOPMENT; MESENCHYME; MORPHOGENESIS; NONHUMAN; PRIORITY JOURNAL; RAT;

ACTIVIN RECEPTORS, TYPE I; ANIMALS; APOPTOSIS; CELL DIVISION; FEMALE; FIBRONECTINS; GLYCOSAMINOGLYCANS; LUNG; MALE; MATRIX METALLOPROTEINASE 2; MORPHOGENESIS; PROTEIN-SERINE-THREONINE KINASES; RATS; RATS, WISTAR; RECEPTORS, TRANSFORMING GROWTH FACTOR BETA; TRANSFORMING GROWTH FACTOR BETA;

ANIMALIA; MAMMALIA;

EID: 0034029875     PISSN: 10588388     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-0177(200004)217:4<343::AID-DVDY2>3.0.CO;2-F     Document Type: Article

References (76)

1. Attisano L, Carcamo J, Ventura F, Weis FM, Massague J, Wrana J. 1993. Identification of human activin and TGF beta type I receptors that form heteromeric kinase complexes with type II receptors. Cell 75:671-680.
2. Attisano L, Wrana JL, López-Casillas F, Massagué J. 1994. TGF-beta receptors and actions. Biochim Biophys Acta 1222:71-80.
3. Becchetti E, Evangeliste E, Stabellini G, Pagliarini A, Del Borello E, Calastrini E, Carinci P. 1988. Developmental heterogeneity of mesenchymal glycosaminoglycan (GAG) distribution in chick embryo lung anlagen. Am J Pathol 188:33-42.
4. Bellusci S, Henderson R, Winnier G, Oikawa T, Hogan BL. 1996. Evidence from normal expression and targeted misexpression that bone morphogenetic protein-4 (BMP-4) plays a role in mouse embryonic lung morphogenesis. Development 122:1693-1702.
5. Bonner JC, Badgett A, Lindroos PM, Osornio-Vargas AR. 1995. Transforming growth factor beta 1 downregulates the platelet-derived growth factor alpha-receptor subtype on human lung fibroblasts in vitro. Am J Respir Cell Mol Biol 13:496-505
6. Caniggia I, Post M. 1992. Differential effect of platelet derived growth factor isoforms on glycosaminoglycan synthesis by fetal lung cells. Am J Physiol 263:L495-L500.
7. Caniggia I, Grissaru-Grasnovsky S, Kuliszewski M, Post M, Lye S. 1999. Normalization of TGFβ3 expression restores trophoblasts invasive capability in preeclamptic pregnancies. J Clin Invest 103: 1641-1650.
8. Chai Y, Mah A, Crohin C, Groff S, Bringas P, Le T, Santos V, Slavkin H. 1994. Specific transforming growth factor-β subtypes regulate embryonic mouse Meckel's cartilage and tooth development. Dev Biol 162:85-103.
9. Cheng HL, Schneider SL, Kane CM, Collinck SO, Grande C, Thompson D, Pietrzak E, Tomasi TB. 1993. TGF-beta 2 gene and protein expression in maternal and fetal tissues at various stages of murine development. J Reprod Immunol 25:133-148.
10. Cheifetz S, Bellon T, Cales C, Vera S, Bernabeu C, Massague J, Letarte M. 1992. Endoglin is a component of the transforming growth factor-beta receptor system in human endothelial cells. J Biol Chem 267:19027-19030.
11. Derynck R, Jarrett JA, Chen EY, Eaton DH, Bell JR, Assosian RK, Roberts AB, Sporn MB, Goeddel DV. 1985. Human transforming growth factor-β complementary DNA sequence and expression in normal and transformed cell. Nature 316:701-705.
12. de Winter JP, ten Dijke P, de Vries CJM, Achterberg TAJ, Sugino H, de Waele P, Huylebroeck D, Verschueren K, van den Eijnden-van Raaij AJM. 1996. Folistatins neutralize activin bioactivity by inhibition of activin binding to its type II receptors. Mol Cell Endocrinol 116:105-114.
13. Fanestil DD, Barrows CH Jr. 1965. Aging in the rotifer. J Gerontol 21:462-469.
14. Franzén F, Ten Dijke P, Ichijo H, Yamashita H, Schulz P, Heldin C-H, Miyazono K. 1993. Cloning of a TGF-β type I receptor that forms a heterodimeric complex with the TGFβ type II receptor. Cell 75:681-692.
15. Gagunka P, Frost G, Shuster S, Cunha G, Formby G, Stern R. 1997. Hyaluronan is a prerequisite for ductal branching morphogenesis. Development 124:3987-3997.
16. Ganan Y, Macias D, Duterque-Coquillaud M, Ros MA, Hurle JM. 1996. Role of TGF betas and BMPs as signals controlling the position of the digits and the areas of interdigital cell death in the developing chick limb autopod.. Development 122:2349-2357.
17. Godkin JD, Dore JJ. 1998. Transforming growth factor beta and the endometrium. Rev Reprod 3:1-6.
18. Greenstein LA, Nissley SP, Moses AC, Short PA, Yang WHY, Lee L, Rechler MM. 1984. In: Barnes DW, Sirbasku DA, Sato GH, editors. Methods for preparation of media, supplements, and substrata for serum-free animal cell culture. New York: Alan R Liss. p 111-138.
19. Heine UI, Munoz EF, Flanders KC, Roberts A, Sporn MB. 1990. Colocalization of TGF-β1 and collagen I and III, fibronectin and glycosaminoglycans during lung branching morphogenesis. Development 109:29-36.
20. Kaartinen V, Voncken JW, Shuler C, Warburton D, Bu D, Heisterkamp N, Groffen J. 1995. Abnormal lung development and cleft palate in mice lacking TGF-β3 indicates defects of epithelial-mesenchymal interaction. Nat Genet 11:415-421.
21. Keijzer R, Post M. 1999. Lung branching morphogenesis: role of growth factors and extracellular matrix. In: Gaultier CL, Bourbon J, Post M, editors. Lung development. Oxford: Oxford University Press. p 1-27.
22. Kulkarni AB, Huh C, Becker D, Geiser A, Lyght M, Flanders KC, Roberts AB, Sporn MB, Ward JM, Karlsson S. 1993. Transforming growth factor-β1 null mutation in mice causes excessive inflammatory response and early death. Proc Natl Acad Sci USA 90:770-774.
23. Letterio JJ, Geiser AG, Kulkarni AB, Roche MB, Roberts AB. 1994. Maternal rescue of transforming growth factor-beta 1 null mice. Science 264:1936-1938.
24. Lin Y, Wang X-F, Ng-Eaton E, Weinberg RA, Lodish H F. 1992. Expression cloning of the TGF-β type II receptor, a functional transmembrane serine/threonine kinase. Cell 68:775-785.
25. Lopéz-Casillas F, Cheifetz S, Doody J, Andres JL, Lane WS, Massagué J. 1991. Structure and expression of the transmembrane proteoglycan, betaglycan, a component of the TGF-β receptor system. Cell 67:785-795.
26. Lopéz-Casillas F, Wrana J, Massagué J. 1993. Betaglycan presents ligand to the TGF beta signaling receptor. Cell 73:1435-1444.
27. Makela TM, Alitalo R, Paulsson Y, Westermark B, Heldin C-H, Alitalo K. 1987. Regulation of platelet-derived growth factor gene expression by transforming growth factor β and phorbol ester in human leukemia cell lines. Mol Cell Biol 7:3656-3662.
28. Massagué J. 1996. TGFβ signaling: receptors, transducers and Mad proteins. Cell 85:947-950.
29. Massagué J, Attisano L, Wrana JL. 1994. The TGF-β family and its composite receptors. Trends Cell Biol 4:172-178.
30. Mignatti P, Rifkin DB, Welgus HG, Parks WC. 1996. Proteinases and tissue remodeling. In: Clark, RAF, editor. The molecular and cellular biology of wound repair. New York: Plenum Press, p 427-474.
31. Miller DA, Lee A, Pelton RW, Chen EY, Moses HC, Derynck R. 1989. Murine transforming growth factor-β2 cDNA sequence and expression in adult tissues and embryos. Mol Endocrinol 3:1108-1114.
32. Minoo P, King RJ. 1994. Epithelial-mesenchymal interaction in lung development. Annu Rev Physiol 56:13-45.
33. Moens CB, Auerbach AB, Conlon RA, Joyner AL, Rossant J. 1992. A targeted mutation reveals a role for N-myc in branching morphogenesis in the embryonic mouse lung. Genes Dev 6:691-704.
34. Moustakas A, Lin HY, Henis YI, O'Connor-McCourt MD, Lodish FH. 1993. The transforming growth factor β receptors type I, II and III form hetrooligomeric complexes in the presence of ligand. J Biol Chem 268:22215-22218.
35. Nudel U, Zakut R, Shani M, Neuman S, Levy Z, Yaffe Y. 1983. The nucleotide sequence of the rat cytoplasmic beta-actin gene. Nucleic Acids Res 11:1759-1771.
36. Pelton RW, Dickinson ME, Moses HL, Hogan BL. 1990. In situ hybridization analysis of TGFβ3 RNA expression during mouse development: comparative studies with TGFβ1 and β2. Development 110:609-620.
37. Pertovaara L, Saksela O, Alitalo K. 1993. Enhanced bFGF gene expression in response to transforming growth factor-beta stimulation of AKR-2B cells. Growth Factors 9:81-86.
38. Peters K, Werner S, Liao S, Wert S, Whitsett JA, Williams LT. 1994. Targeted expression of a dominant negative FGF receptor blocks branching morphogenesis and epithelial differentiation of the mouse lung. EMBO J 13:3296-3301.
39. Post M, Souza P, Liu J, Tseu I, Wang J, Kuliszewski M. 1996. Keratinocyte growth factor and its receptor are involved in regulating early lung branching. Development 122:3107-3115.
40. Post M. 1997. Tissue interactions. In: Crystal RG, West J, Weibel E, Barnes P, editors. The lung. New York: Scientific Foundations Raven Press. p 1003-1013.
41. Roberts AB, Sporn MB. 1990. The transforming growth factors-βs. In: Sporn MB, Roberts AB, editors. Peptide growth factors and their receptors. New York: Springer-Verlag.
42. Rolland G, Xu J, Dupret JM, Post M. 1995. Expression and characterization of type IV collagenases in rat lung cells during development. Exp Cell Res 218:346-350.
43. Roman J, Crough EC, McDonald JA. 1991. Reagents that inhibit fibronectin matrix assembly of cultured cells also inhibit lung branching morphogenesis in vitro. Chest 99:20-21.
44. Roman J, McDonald JA. 1991. Potential role of RGD-directed integrins in mammalian lung branching morphogenesis. Development 112:551-558.
45. Roman J, McDonald JA. 1992. Expression of fibronectin, the integrin α5, and smooth muscle actin in heart and lung development. Am J Respir Cell Mol Biol 6:472-480.
46. Rosenbaum J, Blazejewski S, Preaux AM, Mallat A, Dhumeaux D, Mauvier P. 1995. Fibroblast growth factor 2 and transforming growth factor beta 1 interactions in human liver myofibroblasts. Gastroenterology 109:1986-1996.
47. Rudnick D. 1933. Developmental capacities of the chick lung in chorioallantoic grafts. J Exp Zool 66:125-153.
48. Sanford LP, Ormsby I, Gittenberg-de Groot AC, Sariola H, Friedman R, Biovin GP, Cardell EL, Doetschman T. 1997. TGFβ2 knockout mice have multiple developmental defects that are nonoverlapping with other TGFβ knockout phenotypes. Development 124:2659-2670.
49. Sawai S, Shimono A, Wakamatsu Y, Palmes C, Hanaoka K, Kondoh H. 1993. Defects of embryonic organogenesis resulting from targeted disruption of the N-myc gene in the mouse. Development 117:1445-1455.
50. Schmid P, Cox D, Bilbe G, Maier R, McMaster GK. 1991. Differential expression of TGFβ1, β2 and β3 genes during mouse embryogenesis. Development 111:117-130.
51. Serra R, Pelton RW, Moses HL. 1994. TGFβ1 inhibits branching morphogenesis and N-myc expression in lung bud organ cultures. Development 120:2153-2161.
52. Shull MM, Ormsby I, Kier AB, Pawloski S, Diebold RJ, Yin M, Allen R, Sidman C, Proetzel G, Calvin D, Annunziata N, Doetschman T. 1992. Targeted disruption of the mouse transforming growth factor-beta1 gene results in multifocal inflammatory disease. Nature 359: 693-699.
53. Souza P, O'Brodovich H, Post M. 1995. Lung fluid restriction affects growth but not airway branching of embryonic rat lung. Int J Dev Biol 39:629-637.
54. Souza P, Sedlackova L, Kuliszewski M, Wang J, Liu J, Tseu I, Liu M., Tanswell AK, Post M. 1994. Antisense oligonucleotides targetting PDGF-B mRNA inhibit cell proliferation during embryonic rat lung development. Development 120:2163-2173.
55. Souza P, Kuliszewski M, Wang J, Tseu I, Tanswell AK, Post M. 1995. PDGF-AA and its receptor influence early lung branching morphogenesis via an epithelial-mesenchymal interaction. Development 121:2559-2567.
56. Souza P, Tanswell AK, Post M. 1996. Different roles of PDGF α and β receptors in embryonic rat lung development. Am J Respir Cell Mol Biol 15:551-562.
57. Spooner BS, Thompson-Pletscher HA, Stokes B, Bassett KE. 1986. Extracellular matrix involvement in epithelial branching morphogenesis. In: Steinberg YS, editor. Developmental biology: a comprehensive synthesis. Vol 3. The cell surface in development and cancer. New York: Academic Press. p 225-260.
58. ten Dijke P, Ichijo H, Franzén P, Schulz P, Saras J, Toyoshima H, Heldin C-H, Miyazono K. 1993. Activin receptor-like kinases: a novel subclass of cell-surface receptors with predicted serine/threonine kinase activity. Oncogene 8:2879-2887.
59. Vivien D, Attisano L, Wrana JL, Massague J. 1995. Signaling activity of homologous and heterologous transforming growth factor-beta receptor kinase complexes. J Biol Chem 270:7134-7141.
60. Wang X-F, Lin H, Ng-Easton E, Downward J, Lodish HF, Weinberg RA. 1991. Expression cloning and characterization of the TGF-β type III receptor. Cell 67:797-805.
61. Wang J, Souza P, Kuliszewski M, Tanswell AK, Post M. 1994. Expression of surfactant proteins in embryonic rat lung. Am J Respir Cell Mol Biol 10:222-229.
62. 3. J Biol Chem 270:2722-2728.
63. Weaver M, Yingling JM, Dunn NR, Bellusci S, Hogan BL. 1999. Bmp signaling regulates proximal-distal differentiation of endoderm in mouse lung development. Development 126:4005-4015.
64. Wessels NK. 1977. Tissue interactions and development. Menlo Park (CA): Benjamin/Cummings Inc.
65. Win KM, Charlotte F, Mallat A, Cherqui D, Martin N, Mavier P, Preaux AM, Dhumeaux D, Rosenbaum J. 1993. Mitogenic effect of transforming growth factor-beta1 on human ito cells in culture: evidence for mediation by endogenous platelet-derived growth factor. Hepatology 18:137-145.
66. Woodward TL, Dumont N, O'Connor-McCourt M, Turner JD, Philip A. 1995. Characterization of transforming growth factor-beta growth regulatory effects and receptors on bovine mammary cells. J Cell Physiol 165:339-348.
67. Wrana JL, Attisano L, Wieser R, Ventura F, Massagué J. 1994. Mechanism of activation of the TGF-beta receptor. Nature 370:341-347.
68. Wu X, Roninson CE, Fong HW, Crabtree JS, Rodriquez BR, Roe BA, Gimble JM. 1996. Cloning and characterization of the murine activin receptor like kinase-1 (ALK-1) homolog. Biochem Biophys Res Commun 216:78-83.
69. 3. Am J Physiol 270:L992-L1001.
70. Yokouchi Y, Sakiyama J, Kameda T, Iba H, Suzuki A, Ueno N, Kuroiwa A. 1996. BMP-2/-4 mediate programmed cell death in chicken limb buds. Development 122:3725-3734.
71. Zhao J, Bu D, Lee M, Slavkin HC, Warburton D. 1996. Abrogation of transforming growth factor-beta type II receptor stimulates embryonic mouse branching morphogenesis in culture. Dev Biol 180:250-257.
72. Zhao J, Lee M, Smith S, Warburton D. 1998a. Abrogation of Smad2 and Smad3 or of Smad4 gene expression positively regulates murine embryonic lung branching morphogenesis in culture. Dev Biol 194:182-195.
73. Zhao J, Tefft JD, Lee M, Smith S, Warburton D. 1998b. Abrogation of betaglycan attenuates TGF-beta-mediated inhibition of embryonic murine lung branching morphogenesis in culture. Mech Dev 75:67-79.
74. Zhao J, Sime PJ, Bringas P Jr, Gauldie J, Warburton D. 1998c. Epithelium-specific adenoviral transfer of a dominant-negative mutant TGF-beta type II receptor stimulates embryonic lung branching morphogenesis in culture and potentiates EGF and PDGF-AA. Mech Dev 72:89-100.
75. Zhao Y, Young SL. 1995. Expression of transforming growth factor-beta type II receptor in rat lung is regulated during development. Am J Physiol 269:L419-L426.
76. Zhou L, Dey CR, Wert SE, Whitsett JA. 1996. Arrested lung morphogenesis in transgenic mice bearing an SP-C-TGF-β1 chimeric gene. Dev Biol 175:227-238.