Different Roles for PDGF-α and -β Receptors in Embryonic Lung Development

American Journal of Respiratory Cell and Molecular Biology

Volumn 15, Issue 4, 1996, Pages 551-562

  Souza, Patricia ^a   Tanswell, A Keith ^a   Post, Martin ^a,b  

^a HOSPITAL FOR SICK CHILDREN RESEARCH INSTITUTE   (Canada)

^b HOSPITAL FOR SICK CHILDREN   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ANTISENSE OLIGONUCLEOTIDE; PLATELET DERIVED GROWTH FACTOR ALPHA RECEPTOR; PLATELET DERIVED GROWTH FACTOR BETA RECEPTOR; PLATELET DERIVED GROWTH FACTOR RECEPTOR;

ANIMAL; ARTICLE; DRUG EFFECT; FEMALE; GENE EXPRESSION REGULATION; GENETICS; LUNG; MALE; METABOLISM; MORPHOGENESIS; PREGNANCY; PRENATAL DEVELOPMENT; RAT; WISTAR RAT;

ANIMALS; FEMALE; GENE EXPRESSION REGULATION, DEVELOPMENTAL; LUNG; MALE; MORPHOGENESIS; OLIGONUCLEOTIDES, ANTISENSE; PREGNANCY; RATS; RATS, WISTAR; RECEPTOR, PLATELET-DERIVED GROWTH FACTOR ALPHA; RECEPTOR, PLATELET-DERIVED GROWTH FACTOR BETA; RECEPTORS, PLATELET-DERIVED GROWTH FACTOR;

EID: 0030267586     PISSN: 10441549     EISSN: None     Source Type: Journal    
DOI: 10.1165/ajrcmb.15.4.8879189     Document Type: Article

References (45)

1. Minoo, P., and R. J. King. 1994. Epithelial-mesenchymal interaction in lung development. Annu. Rev. Physiol. 56:13-45.
2. Post, M. 1996. Tissue interactions. In The Lung. R. G. Crystal and J. West, editors. Raven Press, New York. (In press)
3. Goustin, A. S., C. Betsholtz, S. Pfeifer-Ohlsson, H. Persson, J. Rydnert, M. Bywater, G. Holmgren, C.-H. Heldin, B. Westermark, and R. Ohlson. 1985. Coexpression of sis and myc proto-oncogenes in develop human placenta suggests autocrine control of trophoblasts. Cell 41:301-312.
4. Mercola, M., C. Wang, J. Kelley, C. Brownlee, L. Jackson-Grusby, C. Stiles, and D. Bowen-Pope. 1990. Selective expression of PDGF-A and its receptor during early mouse embryogenesis. Dev. Biol. 138:114-122.
5. Raines, E. W., D. F. Bowen-Pope, and R. Ross. 1991. Platelet-derived growth factor. In Peptide Growth Factors and their Receptors I. M. B. Sporn and A. B. Roberts, editors. Springer-Verlag, New York. 173-262.
6. Claesson-Welsh, L. 1994. Signal transduction by the PDGF receptors. Prog. Growth Factors Res. 5:37-54.
7. Ross, R., E. W. Raines, and D. F. Bowen-Pope. 1986. The biology of platelet-derived growth factor. Cell 46:155-169.
8. Pierce, G. F., J. E. Tarpley, D. Yanagihara, T. A. Mustoe, G. M. Fox, and A. Thomason. 1992. Platelet-derived growth factor (BB homodimer), transforming growth factor-beta 1, and basic fibroblast growth factor in dermal wound healing. Neovessel and matrix formation and cessation of repair. Am. J. Pathol. 140:1375-1388.
9. Han, R. N. N., C. Mawdsley, P. Souza, A. K. Tanswell, and M. Post. 1992. Platelet-derived growth factors and growth-related genes in rat lung. III. Immunolocalization during fetal development. Pediatr. Res. 31:323-329.
10. Han, R. N. N., J. Liu, A. K. Tanswell, and M. Post. 1993. Ontogeny of platelet-derived growth factor receptor (PDGFR) in fetal rat lung. Microsc. Res. Tech. 26:381-388.
11. Jasskoll, T. F., G. Don-Wheeler, R. Johnson, and H. C. Slavkin. 1988. Embryonic mouse lung morphogenesis and type II cytodifferentiation in serumless, chemically defined medium using prolonged in vitro cultures. Cell Different. 24:105-117.
12. Souza, P., H. O'Brodovich, and M. Post. 1995. Lung fluid restriction affects growth but not airway branching of embryonic rat lung. Int. J. Dev. Biol. 39:629-637.
13. Souza, P. , L. Sedlackova, M. Kuliszewski, J. Wang, J. Liu, I. Tseu, M. Liu, A. K. Tanswell, and M. Post. 1994. Antisense oligodeoxynucleotides targeting PDGF-B mRNA inhibits cell proliferation during embryonic rat lung development. Development 120:2163-2173.
14. Levéen, P., M. Pekny, S. Gebre-Medhin, B. Swolin, E. Larsson, and C. Betsholtz. 1994. Mice deficient for PDGFB show renal, cardiovascular, and hematological abnormalities. Genes Dev. 8:1875-1887.
15. Soriano, P. 1994. Abnormal kidney development and hematological disorders in PDGF β-receptor mutant mice. Genes Dev. 8:1888-1896.
16. Souza, P., M. Kuliszewski, J. Wang, I. Tseu, A. K. Tanswell, and M. Post. 1995. PDGF-AA and its receptor direct early lung branching via an epithelial-mesenchymal interaction. Development 121:2559-2567.
17. Wang, J., P. Souza, M. Kuliszewski, A. K. Tanswell, and M. Post. 1994. Expression of surfactant proteins in embryonic rat lung. Am. J. Respir. Cell Mol. Biol. 10:222-229.
18. Alonso, S., A. Minty, Y. Bourlet, and M. Buckingham. 1986. Comparison of three actin-coding sequences in the mouse; evolutionary relationships between the actin genes of warm-blooded vertebrates. J. Mol. Evol. 23: 11-22.
19. Greenstein, L. A., S. P. Nissley, A.C. Moses, P. A. Short, W. H.-Y. Yang, L. Lee, and M. M. Rechler. 1984. Purification of multiplication-stimulating activity. In Methods for Preparation of Media, Supplements, and Substrata for Serum-free Animal Cell Culture. D. W. Barnes, D. A. Sirbasku, and G. H. Sato, editors. Alan R. Liss, New York. 111-138.
20. Bradford, M. M. 1976. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem. 72:248-254.
21. 3H]thymidine of proliferative cells in small intestinal epithelium in steady state and after irradiation. Cell Tissue Kinet. 21:317-329.
22. Weibel, E. R. 1962. Volumen und oberfläche der alveolen und kapillaren der menschlichen lunge. Morhometrische Bestimmung von Zahl. Z. Zellforsch. 57:648-666.
23. Fanestil, D. D., and C. H. Barrows, Jr. 1965. Aging in the rotifer. J. Gerontol. 21:462-469.
24. Orr-Urteger, A., and P. Lonai. 1992. Platelet-derived growth factor-A and its receptor are expressed in separate, but adjacent cell layers on the mouse embryo. Development 115:1045-1058.
25. Holmgren, L., A. Glaser, S. Pfeifer-Ohlsson, and R. Ohlsson. 1991. Angiogenesis during human extraembryonic development involves the spatiotemporal control of PDGF ligand and receptor gene expression. Development 113:749-754.
26. Wessells, N. K. 1977. Tissue Interactions and Development. Benjamin/ Cummings Inc., Menlo Park, CA.
27. Heideran, M. A., J.-H. Yu, R. A. Jensen, J. H. Pierce, and S. A. Aaronson. 1992. A deletion in the extracelluar domain of the α platelet-derived growth factor (PDGF) receptor differentially impairs PDGF-AA and PDGF-BB binding affinities. J. Biol. Chem. 267:2884-2887.
28. Vassbotn, F. S., A. Ostman, A. Siegbahn, H. Holmsen, and C.-H. Heldin. 1992. Neomycin is a platelet-derived growth factor (PDGF) antagonist that allows discrimination of PDGF α- and β-receptor signals in cells expressing both receptor types. J. Biol. Chem. 267:15635-15641.
29. Eriksson, A., M. Nistér, P. Leveen, B. Westermark, C.-H. Heldin, and L. Claesson-Welsh. 1991. Induction of platelet-derived growth factor α- and β-receptor mRNA and protein by platelet-derived growth factor. J. Biol. Chem. 266:21138-21144.
30. Raines, E. W., and R. Ross. 1992. Compartmentalization of PDGF on extracellular binding sites dependent on exon-6-encoded sequences. J. Cell Biol. 116:533-543.
31. Caniggia, I., J. Lui, R. Han, S. Buch, K. Funa, A. K. Tanswell, and M. Post. 1993. Fetal lung epithelial cells express receptors for platelet derived growth factor. Am. J. Respir. Cell Mol. Biol. 9:54-63.
32. Raff, M. C., L. E. Lillien, W. D. Richardson, J. F. Burne, and M. D. Noble. 1988. Platelet-derived growth factor from astrocytes drives the clock that times oligodendrocyte development in culture. Nature 333:562-565.
33. Smits, A., M. Kato, B. Westermark, M. Nister, C.-H. Heldin, and K. Funa. 1991. Neurotrophic activity of platelet-derived growth factor (PDGF): rat neuronal cells possess functional PDGF β-type receptors and respond to PDGF. Proc. Natl. Acad. Sci. USA 88:8159-8163.
34. Eriksson, A., A. Siegbahn, B. Westermark, C.-H. Heldin, and L. Claesson-Welsh. 1992. PDGF α- and β-receptors activate unique and common signal transduction pathways. EMBO J. 11:543-550.
35. Siegbahn, A., A. Hammacher, B. Westermark, and C.-H. Heldin. 1990. Differential effects of the various isoforms of platelet-derived growth factor on chemotaxis of fibroblasts, monocytes, and granolucytes. J. Clin. Invest. 85:916-920.
36. Uren, A., J.-C. Yu, N. S. Gholami, J. H. Pierce, and M. A. Heideran. 1994. The αPDGFR tyrosine kinase mediates locomotion of two different cell types through chemotaxis and chemokinesis. Biochem. Biophys. Res. Commun. 204:628-634.
37. Warburton, D., R. Seth, L. Shum, P. G. Horcher, F. L. Hall, Z. Werb, and H. C. Slavkin. 1992. Epigenetic role of epidermal growth factor expression and signalling in embryonic mouse lung morphogenesis. Dev. Biol. 149:123-133.
38. Matrisian, L. M., G. L. Ganser, L. D. Kerr, R. W. Pelton, and L. D. Wood. 1992. Negative regulation of gene expression by TGF-β. Mol. Reprod. Dev. 32:111-120.
39. Schuger, L., J. Varani, R. Mitra, and K. Gilbridge. 1993. Retinoic acid stimulates mouse lung development by a mechanism involving epithelial-mesenchymal interaction and regulation of epidermal growth factor. Dev. Biol. 159:462-473.
40. Jaskoll, T., P. D. Boyer, and M. Melnick. 1994. Tumor necrosis factor-alpha and embryonic mouse lung morphogenesis. Dev. Dynam. 201: 137-150.
41. Peters, K., S. Werner, S. Liao, S. Wert, J. A. Whitsett, and L. T. Williams. 1994. Targeted expression of a dominant negative FGF receptor blocks branching morphogenesis and epithelial differentiation of the mouse lung. EMBO J. 13:3296-3301.
42. Sera, R., R. W. Pelton, and H. L. Moses. 1994. TGFβ1 inhibits branching morphogenesis and N-myc expression in lung bud organ cultures. Development 120:2153-2161.
43. King, K. A., J. S. Torday, and M. Sunday. 1995. Bombesin and [Leu8]phyllitorin promote fetal mouse lung branching morphogenesis via a receptor-mediated mechanism. Proc. Natl. Acad. Sci. USA 92:4357-4361.
44. Stephenson, D. A., M. Mercola, E. Anderson, C. Wang, C. D. Stiles, D. F. Bowen-Pope, and V. M. Chapman. 1991. The platelet-derived growth factor alpha subunit gene is deleted in the mouse mutation patch (Ph). Proc. Natl. Acad. Sci. USA 88:6-10.
45. Orr-Urteger, A., M. Bedford, M.-S. Do, L. Eisenbach, and P. Lonai. 1992. Developmental expression of the α receptor for platelet-derived growth factor, which is deleted in the embryonic lethal Patch mutation. Development 115:289-303.