Glucocorticoid-induced tropoelastin expression is mediated via transforming growth factor-β3

American Journal of Physiology - Lung Cellular and Molecular Physiology

Volumn 270, Issue 6 14-6, 1996, Pages

  Yee, Wendy ^a   Wang, Jinxia ^a   Liu, Jason ^a   Tseu, Irene ^a   Kuliszewski, Maciej ^a   Post, Martin ^a,b  

^a UNIVERSITY OF TORONTO   (Canada)

^b HOSPITAL FOR SICK CHILDREN   (Canada)

Author keywords

fetal lung; fibroblasts; glucocorticoids

Indexed keywords

COMPLEMENTARY DNA; GLUCOCORTICOID; HYDROCORTISONE; MESSENGER RNA; TRANSFORMING GROWTH FACTOR BETA3; TROPOELASTIN;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DNA SEQUENCE; FEMALE; FETUS; FETUS LUNG; LUNG FIBROBLAST; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DETERMINATION; PROTEIN EXPRESSION; RAT; SEQUENCE HOMOLOGY; TRANSCRIPTION REGULATION;

EID: 0029737097     PISSN: 10400605     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajplung.1996.270.6.l992     Document Type: Article

References (33)

1. Attisano, L., J. L. Wrana, F. López-Casillas, and J. Massagué. TGF-beta receptors and actions. Biochim. Biophys. Acta 1222: 71-80, 1994.
2. Ballard, P. L. Hormones and lung maturation. In: Monographs on Endocrinology. Berlin: Springer-Verlag, 1986, vol. 28.
3. 3H)dexamethasone binding in fetal lung. Dev. Biol. 105: 351-364, 1984.
4. Bretell, L., and S. A. McGowan. Basic fibroblast growth factor decreases elastin production by neonatal rat lung fibroblasts. Am. J. Respir. Cell Mol. Biol. 10: 306-315, 1994.
5. Bruce, M. Developmental changes in tropoelastin mRNA levels in rat lung: evaluation by in situ hybridization. Am. J. Respir. Cell Mol. Biol. 5: 344-350, 1991.
6. Caniggia, I., A. K. Tanswell, and M. Post. Spatial and temporal differences in glycosaminoglycan synthesis by fetal lung fibroblasts. Exp. Cell Res. 202: 252-258, 1992.
7. Caniggia, I., I. Tseu, R. N. N Han, B. T. Smith, A. K. Tanswell, and M. Post. Spatial and temporal differences in fibroblast behavior in fetal rat lung. Am. J. Physiol. 261 (Lung Cell. Mol. Physiol. 5): L424-L433, 1991.
8. Chomczynski, P., and N. Sacchi. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal. Biochem. 162: 156-159, 1987.
9. Cole, T. J., J. A. Blendy, P. Monaghan, K. Krieglstein, W. Schmid, A. Aguzzi, E. Fantuzzi, E. Hummler, K. Unsicker, and G. Schütz. Targeted disruption of the glucocorticoid receptor blocks adrenergic chromaffin cell development and severely retards lung maturation. Genes Dev. 9: 1611-1621, 1995.
10. Deak, S. B., R. A. Pierce, S. A. Belsky, D. J. Riley, and C. D. Boyd. Rat tropoelastin is synthesized from a 3.5-kilobase mRNA. J. Biol. Chem. 263: 13504-13507, 1988.
11. Foster, J. A., and S. Curtiss. The regulation of elastin synthesis. Am. J. Physiol. 259 (Lung Cell. Mol. Physiol. 3): L13-L23, 1990.
12. Franzén, F., P. Ten Dijke, H. Ichijo, H. Yamashita, P. Schulz, C.-H. Heldin, and K. Miyazono. Cloning of a TGF-β type I receptor that forms a heterodimeric complex with the TGF β type II receptor. Cell 75: 681-692, 1993.
13. Hirt, R., O. Poulain-Godefroy, J. Bilotte, J.-P. Krahenbuhl, and N. Fasel. Highly inducible synthesis of heterologous proteins in epithelial cells carrying a glucocorticoid-responsive vector. Gene 111: 199-206, 1992.
14. Honig, L. S., B. T. Smith, H. C. Slavkin, and H. G. Donahue. Influence of the major histocompatibility complex (H-2) on glucocorticoid-stimulated pulmonary surfactant synthesis in two congenic mouse strains. Proc. Soc. Exp. Biol. Med. 176: 419-425, 1984.
15. Kähäri, V.-M., D. R. Olsen, R. W. Rhudy, P. Carrillo, Y. Q. Chen, and J. Uitto. Transforming growth factor-beta upregulates elastin gene expression in human skin fibroblasts. Evidence for post-transcriptional regulation. Lab. Invest. 66: 580-588, 1992.
16. Lin, Y., X.-F. Wang, E. Ng-Eaton, R. A. Weinberg, and H. F. Lodish. Expression cloning of the TGF-β type II receptor, a functional transmembrane serine/threonine kinase. Cell 68:775-785, 1992.
17. Marigo, V., D. Volpin, G. Vitale, and G. M. Bressan. Identification of a TGF-β responsive element in the human elastin promoter. Biochem. Biophys. Res. Commun. 199: 1049-1056, 1994.
18. McGowan, S. E. Influences of endogenous and exogenous TGF-β on elastin in rat lung fibroblasts and aortic smooth muscle cells. Am. J. Physiol. 263 (Lung Cell. Mol. Physiol. 7): L257-L263, 1992.
19. McGowan, S. E., and R. McNamer. Transforming growth factor-β increases elastin production by neonatal rat lung fibroblasts. Am. J. Respir. Cell Mol. Biol. 3: 369-376, 1990.
20. Noguchi, A., K. Firsching, J. D. Kursar, and R. Reddy. Developmental changes in tropoelastin synthesis by rat pulmonary fibroblasts and effect of dexamethasone. Pediatr. Res. 28: 379-382, 1990.
21. Noguchi, A., and H. Samaha. Developmental changes in tropoelastin gene expression in the rat lung studied by in situ hybridization. Am. J. Respir. Cell Mol. Biol. 5: 571-578, 1991.
22. Pierce, R. A., W. I. Mariencheck, S. Sandefur, E. C. Crouch, and W. C. Parks. Glucocorticoids upregulate tropoelastin expression during late stages of fetal lung development. Am. J. Physiol. 268 (Lung Cell. Mol. Physiol. 12): L491-L500, 1995.
23. Post, M., and B. T. Smith. Hormonal control of surfactant metabolism. In: Pulmonary Surfactant: From Molecular Biology to Clinical Practice, edited by B. Robertson, L. M. G. Van Golde, and J. J. Batenburg. Amsterdam: Elsevier, 1992, p. 379-424.
24. Rich, C., D. Z. Ewton, B. M. Martin, J. R. Florini, M. Bashir, J. Rosenbloom, and J. A. Foster. IGF-1 regulation of elastogenesis: comparison of aortic and lung cells. Am. J. Physiol. 263 (Lung Cell. Mol. Physiol. 7): L276-L282, 1992.
25. Roberts, A. B., and M. B. Sporn. The transforming growth factors-βs. In: Peptide Growth Factors and Their Receptors, edited by M. B. Sporn and A. B. Roberts. New York: Springer-Verlag, 1990, p. 419-472.
26. Schellenberg, J. C., G. C. Liggins, and A. W. Stewart. Growth, elastin concentration, and collagen concentration of perinatal rat lung: effects of dexamethasone. Pediatr. Res. 21: 603-607, 1987.
27. Souza, P., M. Kuliszewski, J. Wang, I. Tseu, K. Tanswell, and M. Post. PDGF-AA and its receptor direct early lung branching via an epithelial-mesenchymal interaction. Development 121: 2559-2567, 1995.
28. Sweezey, N., C. Mawdsley, F. Ghibu, L. Song, S. Buch, A. Moore, T. Antakly, and M. Post. Differential regulation of glucocorticoid receptor expression in fetal rat lung cells. Pediatr. Res. 38: 506-512, 1995.
29. Thurlbeck, W. M. Postnatal growth and development of the lung. Am. Rev. Respir. Dis. 111: 803-844, 1975.
30. Torday, J. S., M. Post, and B. T. Smith. Compartmentalization of 11-oxidoreductase within the fetal lung alveolus. Am. J. Physiol. 249 (Cell Physiol. 18): C173-C176, 1985.
31. 3. J. Biol. Chem. 270: 2722-2728, 1995.
32. Wrana, J. L., L. Attisano, R. Wieser, F. Ventura, and J. Massagué. Mechanism of activation of the TGF-beta receptor. Nature Lond. 370: 341-347, 1994.
33. Wolfe, B. L., C. B. Rich, H. D. Goud, M. Terpstra, M. Bashir, J. Rosenbloom, G. E. Sonenheim, and J. A. Foster. Insulin-like growth factor-I regulates transcription of the elastine gene. J. Biol. Chem. 268: 12418-12426, 1993.