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Volumn 74, Issue 6, 2000, Pages 2380-2391

Pregnenolone sulfate, a naturally occurring excitotoxin involved in delayed retinal cell death

Author keywords

17 Estradiol; Apoptosis; Dehydroepiandrosterone; Dehydroepiandrosterone sulfate ester; DNA fragmentation; NMDA receptors; Pregnenolone sulfate; Progesterone; Superoxide dismutase; Thiobarbituric acid reactive substances

Indexed keywords

4 (3 PHOSPHONOPROPYL) 2 PIPERAZINECARBOXYLIC ACID; 6 CYANO 7 NITRO 2,3 QUINOXALINEDIONE; ESTRADIOL; LACTATE DEHYDROGENASE; N METHYL DEXTRO ASPARTIC ACID; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; NEUROSTEROID; PRASTERONE; PRASTERONE SULFATE; PREGNENOLONE SULFATE; PROGESTERONE; SUPEROXIDE DISMUTASE; THIOBARBITURIC ACID REACTIVE SUBSTANCE;

EID: 0034025340     PISSN: 00223042     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1471-4159.2000.0742380.x     Document Type: Article
Times cited : (24)

References (80)
  • 1
    • 0030576540 scopus 로고    scopus 로고
    • Antioxidant activity of dioscorea and dehydroepiandrosterone (DHEA) in older humans
    • Araghiniknam M., Chung S., Nelso-White T., Eskelson C., and Watson R. R. (1996) Antioxidant activity of dioscorea and dehydroepiandrosterone (DHEA) in older humans. Life Sci. 59, PL147-PL157.
    • (1996) Life Sci. , vol.59
    • Araghiniknam, M.1    Chung, S.2    Nelso-White, T.3    Eskelson, C.4    Watson, R.R.5
  • 2
    • 0028153304 scopus 로고
    • Prevention of carbon tetrachloride-induced lipid peroxidation in liver microsomes from dehydroepiandrosterone-pretreated rats
    • Aragno M., Tamagno E., Poli G., Boccuzzi G., Brignardello E., and Danni O. (1994) Prevention of carbon tetrachloride-induced lipid peroxidation in liver microsomes from dehydroepiandrosterone-pretreated rats. Free Radic. Res. 21, 427-435.
    • (1994) Free Radic. Res. , vol.21 , pp. 427-435
    • Aragno, M.1    Tamagno, E.2    Poli, G.3    Boccuzzi, G.4    Brignardello, E.5    Danni, O.6
  • 3
    • 0030630595 scopus 로고    scopus 로고
    • Neurosteroids: Of the nervous system, by the nervous system, for the nervous system
    • Baulieu E. E. (1997) Neurosteroids: of the nervous system, by the nervous system, for the nervous system. Recent Prog. Horm. Res. 52, 1-32.
    • (1997) Recent Prog. Horm. Res. , vol.52 , pp. 1-32
    • Baulieu, E.E.1
  • 5
    • 0025189864 scopus 로고
    • Apparent hydroxyl radical production by peroxynitrite: Implication for endothelial injury from nitric oxide and superoxide
    • Beckman J. S., Beckman T. W., Chen J., Marshall P. A., and Freeman B. A. (1990) Apparent hydroxyl radical production by peroxynitrite: implication for endothelial injury from nitric oxide and superoxide. Proc. Natl. Acad. Sci. USA 87, 1620-1624.
    • (1990) Proc. Natl. Acad. Sci. USA , vol.87 , pp. 1620-1624
    • Beckman, J.S.1    Beckman, T.W.2    Chen, J.3    Marshall, P.A.4    Freeman, B.A.5
  • 6
    • 0030008052 scopus 로고    scopus 로고
    • Superoxide production in rat hippocampal neurons: Selective imaging with hydroethidine
    • Bindokas V. P., Jordan J., Lee C. C., and Miller R. J. (1996) Superoxide production in rat hippocampal neurons: selective imaging with hydroethidine. J. Neurosci. 16, 1324-1326.
    • (1996) J. Neurosci. , vol.16 , pp. 1324-1326
    • Bindokas, V.P.1    Jordan, J.2    Lee, C.C.3    Miller, R.J.4
  • 7
    • 0029153913 scopus 로고
    • Apoptosis and necrosis: Two distinct events induced, respectively, by mild and intense insults with N-methyl-D-aspartate or nitric oxide/superoxide in cortical cell cultures
    • Bonfoco E., Krainc D., Ankarcrona M., Nicotera P., and Lipton S. A. (1995) Apoptosis and necrosis: two distinct events induced, respectively, by mild and intense insults with N-methyl-D-aspartate or nitric oxide/superoxide in cortical cell cultures. Proc. Natl. Acad. Sci. USA 92, 7162-7166.
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 7162-7166
    • Bonfoco, E.1    Krainc, D.2    Ankarcrona, M.3    Nicotera, P.4    Lipton, S.A.5
  • 8
    • 0032033869 scopus 로고    scopus 로고
    • Free radicals in retinal ischemia
    • Bonne C., Muller A., and Villain M. (1998) Free radicals in retinal ischemia. Gen. Pharmacol. 30, 275-280.
    • (1998) Gen. Pharmacol. , vol.30 , pp. 275-280
    • Bonne, C.1    Muller, A.2    Villain, M.3
  • 9
    • 0026343685 scopus 로고
    • Ageing of the retinal pigment epithelium
    • Osborne N. and Chader G., eds, Pergamon Press, London
    • Boulton M. (1991) Ageing of the retinal pigment epithelium, in Progress in Retina Research (Osborne N. and Chader G., eds), pp. 125-151. Pergamon Press, London.
    • (1991) Progress in Retina Research , pp. 125-151
    • Boulton, M.1
  • 10
    • 0026544582 scopus 로고
    • Involvement of lipid peroxidation in CNS injury
    • Braughler J. M. and Hall E. D. (1986) Involvement of lipid peroxidation in CNS injury. J. Neurotrauma 9, 1-7.
    • (1986) J. Neurotrauma , vol.9 , pp. 1-7
    • Braughler, J.M.1    Hall, E.D.2
  • 11
    • 0029614765 scopus 로고
    • Neuronal apoptosis
    • Bredesen D. E. (1995) Neuronal apoptosis. Ann. Neurol. 38, 839-851.
    • (1995) Ann. Neurol. , vol.38 , pp. 839-851
    • Bredesen, D.E.1
  • 12
    • 0017872475 scopus 로고
    • Microsomal lipid peroxidation
    • Packer L. and Glazer A. N., eds, Academic Press, New York
    • Buege J. A. and Aust S. D. (1978) Microsomal lipid peroxidation, in Methods in Enzymology, Vol. 52 (Packer L. and Glazer A. N., eds), pp. 302-310. Academic Press, New York.
    • (1978) Methods in Enzymology , vol.52 , pp. 302-310
    • Buege, J.A.1    Aust, S.D.2
  • 13
    • 0025580503 scopus 로고
    • Attenuation of glutamate-induced neuronal swelling and toxicity in transgenic mice overexpressing human CuZn-superoxide dismutase
    • Chan P. H., Chu L., Chen S. F., Carlson E. J., and Epstein C. (1990) Attenuation of glutamate-induced neuronal swelling and toxicity in transgenic mice overexpressing human CuZn-superoxide dismutase. Acta Neurochir. (Wien) 51, 245-247.
    • (1990) Acta Neurochir. (Wien) , vol.51 , pp. 245-247
    • Chan, P.H.1    Chu, L.2    Chen, S.F.3    Carlson, E.J.4    Epstein, C.5
  • 14
    • 0024093449 scopus 로고
    • Glutamate neurotoxicity and diseases of the nervous system
    • Choi D. W. (1988) Glutamate neurotoxicity and diseases of the nervous system. Neuron 1, 623-634.
    • (1988) Neuron , vol.1 , pp. 623-634
    • Choi, D.W.1
  • 15
    • 0023891771 scopus 로고    scopus 로고
    • Involvement of excitatory neurotransmitters in the damage produced in chick embryo retinas by anoxia and extracellular high potassium
    • David P., Lusky M., and Teichberg V. I. (1998) Involvement of excitatory neurotransmitters in the damage produced in chick embryo retinas by anoxia and extracellular high potassium. Exp. Eye Res. 46, 657-662.
    • (1998) Exp. Eye Res. , vol.46 , pp. 657-662
    • David, P.1    Lusky, M.2    Teichberg, V.I.3
  • 16
    • 0028918483 scopus 로고
    • Transcriptional or translational inhibition blocks low dose NMDA-mediated cell death
    • Dreyer E. B., Zhang D., and Lipton S. A. (1995) Transcriptional or translational inhibition blocks low dose NMDA-mediated cell death. Neuroreport 6, 942-944.
    • (1995) Neuroreport , vol.6 , pp. 942-944
    • Dreyer, E.B.1    Zhang, D.2    Lipton, S.A.3
  • 18
    • 0030015455 scopus 로고    scopus 로고
    • Isolation and characterization of a stereospecific 3β-hydroxysteroid sulfotransferase (pregnenolone sulfotransferase) cDNA
    • Dufort I., Tremblay Y., Bélanger A., Labrie F., and Luu-The V. (1996) Isolation and characterization of a stereospecific 3β-hydroxysteroid sulfotransferase (pregnenolone sulfotransferase) cDNA. DNA Cell Biol. 15, 481-487.
    • (1996) DNA Cell Biol. , vol.15 , pp. 481-487
    • Dufort, I.1    Tremblay, Y.2    Bélanger, A.3    Labrie, F.4    Luu-The, V.5
  • 20
    • 2642643751 scopus 로고    scopus 로고
    • Immunocytochemical characterization of quisqualic acid- and N-methyl-D-aspartate-induced excitotoxicity in the retina of chicks
    • Fischer A. J., Seltner R. L. P., Poon J., and Stell W. K. (1998) Immunocytochemical characterization of quisqualic acid- and N-methyl-D-aspartate-induced excitotoxicity in the retina of chicks. J. Comp. Neurol. 393, 1-15.
    • (1998) J. Comp. Neurol. , vol.393 , pp. 1-15
    • Fischer, A.J.1    Seltner, R.L.P.2    Poon, J.3    Stell, W.K.4
  • 21
    • 0028853687 scopus 로고
    • Pregnenolone sulfate enhances post-training memory processes when injected in very low doses into limbic system structures: The amygdala is by far the most sensitive
    • Flood J. F., Morley J. E., and Roberts E. (1995) Pregnenolone sulfate enhances post-training memory processes when injected in very low doses into limbic system structures: the amygdala is by far the most sensitive. Proc. Natl. Acad. Sci. USA 92, 10806-10810.
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 10806-10810
    • Flood, J.F.1    Morley, J.E.2    Roberts, E.3
  • 22
    • 0033135367 scopus 로고    scopus 로고
    • Manganese superoxide dismutase mediates the early release of mitochondrial cytochrome c and subsequent DNA fragmentation after permeant focal cerebral ischemia in mice
    • Fujimura M., Morita-Fujimura Y., Kawase M., Copin J. C., Calagui B., Epstein C. J., and Chan P. H. (1999) Manganese superoxide dismutase mediates the early release of mitochondrial cytochrome c and subsequent DNA fragmentation after permeant focal cerebral ischemia in mice. J. Neurosci. 19, 3414-3422.
    • (1999) J. Neurosci. , vol.19 , pp. 3414-3422
    • Fujimura, M.1    Morita-Fujimura, Y.2    Kawase, M.3    Copin, J.C.4    Calagui, B.5    Epstein, C.J.6    Chan, P.H.7
  • 23
    • 0029014903 scopus 로고
    • Multiple pathways are involved in protection of MCF-7 cells against death due to protein synthesis inhibition
    • Geier A., Weiss C., Beery R., Haimsohn M., Hemi R., Malik Z., and Karasik A. (1995) Multiple pathways are involved in protection of MCF-7 cells against death due to protein synthesis inhibition. J. Cell. Physiol. 160, 570-576.
    • (1995) J. Cell. Physiol. , vol.160 , pp. 570-576
    • Geier, A.1    Weiss, C.2    Beery, R.3    Haimsohn, M.4    Hemi, R.5    Malik, Z.6    Karasik, A.7
  • 24
    • 0029924284 scopus 로고    scopus 로고
    • Estrogens attenuate and corticosterone exacerbates excitotoxicity, oxidative injury, and amyloid β-peptide toxicity in hippocampal neurons
    • Goodman Y., Bruce A. J., Cheng B., and Mattson M. P. (1996) Estrogens attenuate and corticosterone exacerbates excitotoxicity, oxidative injury, and amyloid β-peptide toxicity in hippocampal neurons. J. Neurochem. 66, 1836-1844.
    • (1996) J. Neurochem. , vol.66 , pp. 1836-1844
    • Goodman, Y.1    Bruce, A.J.2    Cheng, B.3    Mattson, M.P.4
  • 25
    • 0031404546 scopus 로고    scopus 로고
    • Phenolic a ring requirement for the neuroprotective effects of steroids
    • Green P. S., Gordon K., and Simpkins J. W. (1997) Phenolic A ring requirement for the neuroprotective effects of steroids. J. Steroid Mol. Biol. 3, 229-235.
    • (1997) J. Steroid Mol. Biol. , vol.3 , pp. 229-235
    • Green, P.S.1    Gordon, K.2    Simpkins, J.W.3
  • 26
    • 0028893492 scopus 로고
    • Superoxide dismutase delays neuronal apoptosis: A role for reactive oxygen species in programmed neuronal death
    • Greenlund L. J. S., Deckwerth T. L., and Johnson E. M. Jr. (1995) Superoxide dismutase delays neuronal apoptosis: a role for reactive oxygen species in programmed neuronal death. Neuron 14, 303-315.
    • (1995) Neuron , vol.14 , pp. 303-315
    • Greenlund, L.J.S.1    Deckwerth, T.L.2    Johnson E.M., Jr.3
  • 28
    • 0028978581 scopus 로고
    • γ-Aminobutyric acid type A/benzodiazepine receptors regulate rat retina neurosteroidogenesis
    • Guarneri P., Guarneri R., Cascio C., Piccoli F., and Papadopoulos V. (1995) γ-Aminobutyric acid type A/benzodiazepine receptors regulate rat retina neurosteroidogenesis. Brain Res. 683, 65-72.
    • (1995) Brain Res. , vol.683 , pp. 65-72
    • Guarneri, P.1    Guarneri, R.2    Cascio, C.3    Piccoli, F.4    Papadopoulos, V.5
  • 29
    • 0031817944 scopus 로고    scopus 로고
    • Induction of neurosteroid synthesis by NMDA receptors in isolated rat retina: A potential early event in excitotoxicity
    • Guarneri P., Russo D., Cascio C., De Leo G., Piccoli F., and Guarneri R. (1998a) Induction of neurosteroid synthesis by NMDA receptors in isolated rat retina: a potential early event in excitotoxicity. Eur. J. Neurosci. 10, 1752-1763.
    • (1998) Eur. J. Neurosci. , vol.10 , pp. 1752-1763
    • Guarneri, P.1    Russo, D.2    Cascio, C.3    De Leo, G.4    Piccoli, F.5    Guarneri, R.6
  • 30
    • 0032534523 scopus 로고    scopus 로고
    • Pregnenolone sulfate modulates NMDA receptors, inducing and potentiating acute excitotoxicity in isolated retina
    • Guarneri P., Russo D., Cascio C., De Leo G., Piccoli T., Sciuto V., Piccoli F., and Guarneri R. (1998b) Pregnenolone sulfate modulates NMDA receptors, inducing and potentiating acute excitotoxicity in isolated retina. J. Neurosci. Res. 54, 787-797.
    • (1998) J. Neurosci. Res. , vol.54 , pp. 787-797
    • Guarneri, P.1    Russo, D.2    Cascio, C.3    De Leo, G.4    Piccoli, T.5    Sciuto, V.6    Piccoli, F.7    Guarneri, R.8
  • 31
    • 0029048295 scopus 로고
    • Blockade of glutamate receptors unmasks neuronal apoptosis after oxygen-glucose deprivation in vitro
    • Gwag B. J., Lobner D., Koh J. Y., Wie M. B., and Choi D. W. (1995) Blockade of glutamate receptors unmasks neuronal apoptosis after oxygen-glucose deprivation in vitro. J. Neurosci. 68, 615-619.
    • (1995) J. Neurosci. , vol.68 , pp. 615-619
    • Gwag, B.J.1    Lobner, D.2    Koh, J.Y.3    Wie, M.B.4    Choi, D.W.5
  • 32
    • 0026754574 scopus 로고
    • Reactive oxygen species and the central nervous system
    • Halliwell B. (1992) Reactive oxygen species and the central nervous system. J. Neurochem. 59, 1609-1623.
    • (1992) J. Neurochem. , vol.59 , pp. 1609-1623
    • Halliwell, B.1
  • 36
    • 17344371804 scopus 로고    scopus 로고
    • Mitochondrial manganese superoxide dismutase prevents neural apoptosis and reduces ischemic brain injury: Suppression of peroxynitrite production, lipid peroxidation, and mitochondrial dysfunction
    • Keller J. N., Kindy M. S., Holtsberg F. W., St. Clair D. K., Yen H. C., Germeyer A., Steiner S. M., Bruce-Keller A. J., Hutchins J. B., and Mattson M. P. (1998) Mitochondrial manganese superoxide dismutase prevents neural apoptosis and reduces ischemic brain injury: suppression of peroxynitrite production, lipid peroxidation, and mitochondrial dysfunction. J. Neurosci. 18, 687-697.
    • (1998) J. Neurosci. , vol.18 , pp. 687-697
    • Keller, J.N.1    Kindy, M.S.2    Holtsberg, F.W.3    St. Clair, D.K.4    Yen, H.C.5    Germeyer, A.6    Steiner, S.M.7    Bruce-Keller, A.J.8    Hutchins, J.B.9    Mattson, M.P.10
  • 38
    • 0029866196 scopus 로고    scopus 로고
    • 4-Hydroxyhexenal is a potent inducer of mitochondrial permeability transition
    • Kristal B. S., Park B. K., and Yu B. P. (1996) 4-Hydroxyhexenal is a potent inducer of mitochondrial permeability transition. J. Biol. Chem. 271, 6033-6038.
    • (1996) J. Biol. Chem. , vol.271 , pp. 6033-6038
    • Kristal, B.S.1    Park, B.K.2    Yu, B.P.3
  • 39
    • 0027221998 scopus 로고
    • NMDA-dependent superoxide production and neurotoxicity
    • Lafon-Cazal M., Pietri S., Culcasi M., and Bockaert J. (1993) NMDA-dependent superoxide production and neurotoxicity. Nature 364, 535-537.
    • (1993) Nature , vol.364 , pp. 535-537
    • Lafon-Cazal, M.1    Pietri, S.2    Culcasi, M.3    Bockaert, J.4
  • 41
    • 0031442999 scopus 로고    scopus 로고
    • Caspase-mediated apoptosis in neuronal excitotoxicity triggered by nitric oxide
    • Leist M., Volbracht C., Kühnle S., Fava E., Ferrando-May E., and Nicotera P. (1997) Caspase-mediated apoptosis in neuronal excitotoxicity triggered by nitric oxide. Mol. Med. 3, 750-764.
    • (1997) Mol. Med. , vol.3 , pp. 750-764
    • Leist, M.1    Volbracht, C.2    Kühnle, S.3    Fava, E.4    Ferrando-May, E.5    Nicotera, P.6
  • 42
    • 0028800150 scopus 로고
    • Reversal of scopolamine induced amnesia in rats by the steroid sulfatase inhibitor estrone-3-O-sulfamate
    • Li P. K., Rhodes M. E., Jagannathan S., and Johnson D. A. (1995) Reversal of scopolamine induced amnesia in rats by the steroid sulfatase inhibitor estrone-3-O-sulfamate. Cogn. Brain Res. 2, 251-254.
    • (1995) Cogn. Brain Res. , vol.2 , pp. 251-254
    • Li, P.K.1    Rhodes, M.E.2    Jagannathan, S.3    Johnson, D.A.4
  • 43
    • 0031713541 scopus 로고    scopus 로고
    • Excitotoxicity, free radicals, necrosis and apoptosis
    • Lipton S. A. and Nicotera P. (1998) Excitotoxicity, free radicals, necrosis and apoptosis. Neuroscientist 4, 345-352.
    • (1998) Neuroscientist , vol.4 , pp. 345-352
    • Lipton, S.A.1    Nicotera, P.2
  • 44
    • 0028762647 scopus 로고
    • Excitatory amino acids as a final common pathway for neurological disorders
    • Lipton S. A. and Rosenberg P. A. (1994) Excitatory amino acids as a final common pathway for neurological disorders. N. Engl. J. Med. 330, 613-622.
    • (1994) N. Engl. J. Med. , vol.330 , pp. 613-622
    • Lipton, S.A.1    Rosenberg, P.A.2
  • 46
    • 0026732022 scopus 로고
    • Pregnenolone sulfate increases the convulsant potency of N-methyl-D-aspartate in mice
    • Maione S., Berrino L., Vitagliano S., Leyva J., and Rossi F. (1992) Pregnenolone sulfate increases the convulsant potency of N-methyl-D-aspartate in mice. Eur. J. Pharmacol. 219, 477-479.
    • (1992) Eur. J. Pharmacol. , vol.219 , pp. 477-479
    • Maione, S.1    Berrino, L.2    Vitagliano, S.3    Leyva, J.4    Rossi, F.5
  • 47
    • 0026509649 scopus 로고
    • A receptor. Mechanism of action and physiological significance
    • A receptor. Mechanism of action and physiological significance. Prog. Neurobiol. 38, 379-395.
    • (1992) Prog. Neurobiol. , vol.38 , pp. 379-395
    • Majewska, M.D.1
  • 49
    • 0031020476 scopus 로고    scopus 로고
    • A role for 4-hydroxynonenal, an aldehydic product of lipid peroxidation, in disruption of ion homeostasis and neuronal death induced by amyloid β-peptide
    • Mark R. J., Lovell M. A., Markesbery W. R., Uchida K., and Mattson M. P. (1997) A role for 4-hydroxynonenal, an aldehydic product of lipid peroxidation, in disruption of ion homeostasis and neuronal death induced by amyloid β-peptide. J. Neurochem. 68, 255-264.
    • (1997) J. Neurochem. , vol.68 , pp. 255-264
    • Mark, R.J.1    Lovell, M.A.2    Markesbery, W.R.3    Uchida, K.4    Mattson, M.P.5
  • 50
    • 0028032491 scopus 로고
    • The neurosteroid pregnenolone sulfate blocks NMDA antagonist-induced deficits in a passive avoidance memory task
    • Mathis C., Paul M. S., and Crawley N. J. (1994) The neurosteroid pregnenolone sulfate blocks NMDA antagonist-induced deficits in a passive avoidance memory task. Psychopharmacology (Berl.) 116, 201-206.
    • (1994) Psychopharmacology (Berl.) , vol.116 , pp. 201-206
    • Mathis, C.1    Paul, M.S.2    Crawley, N.J.3
  • 51
    • 0032007328 scopus 로고    scopus 로고
    • Modification of ion homeostasis by lipid peroxidation: Roles in neuronal degeneration and adaptive plasticity
    • Mattson M. P. (1998) Modification of ion homeostasis by lipid peroxidation: roles in neuronal degeneration and adaptive plasticity. Trends Neurosci. 20, 53-57.
    • (1998) Trends Neurosci. , vol.20 , pp. 53-57
    • Mattson, M.P.1
  • 52
    • 0029150526 scopus 로고
    • 2+ concentration, and neurotoxicity and increase antioxidant enzyme activities in hippocampal neurons
    • 2+ concentration, and neurotoxicity and increase antioxidant enzyme activities in hippocampal neurons. J. Neurochem. 65, 1740-1751.
    • (1995) J. Neurochem. , vol.65 , pp. 1740-1751
    • Mattson, M.P.1    Lovell, M.A.2    Furukawa, K.3    Markesbery, W.R.4
  • 53
    • 0030986689 scopus 로고    scopus 로고
    • 1 receptor agonist properties, facilitates NMDA receptor-dependent learning in mice
    • 1 receptor agonist properties, facilitates NMDA receptor-dependent learning in mice. Eur. J. Pharmacol. 328, 9-18.
    • (1997) Eur. J. Pharmacol. , vol.328 , pp. 9-18
    • Maurice, T.1    Privat, A.2
  • 54
    • 0343151032 scopus 로고    scopus 로고
    • Dehydroepinadrosterone sulfate attenuates dizocilpine-induced learning impairment in mice via sigma 1-receptors
    • Maurice T., Junien J. L., and Privat A. (1997) Dehydroepinadrosterone sulfate attenuates dizocilpine-induced learning impairment in mice via sigma 1-receptors. Behav. Brain Res. 83, 159-164.
    • (1997) Behav. Brain Res. , vol.83 , pp. 159-164
    • Maurice, T.1    Junien, J.L.2    Privat, A.3
  • 55
    • 0032518022 scopus 로고    scopus 로고
    • Protective and damaging effects of stress mediators
    • McEwen B. S. (1998) Protective and damaging effects of stress mediators. N. Engl. J. Med. 338, 171-179.
    • (1998) N. Engl. J. Med. , vol.338 , pp. 171-179
    • McEwen, B.S.1
  • 56
    • 0025063609 scopus 로고
    • Excitatory amino acid neurotoxicity and neurodegenerative disease
    • Meldrum B. and Garthwaite J. (1990) Excitatory amino acid neurotoxicity and neurodegenerative disease. Trends Pharmacol. Sci. 11, 379-387.
    • (1990) Trends Pharmacol. Sci. , vol.11 , pp. 379-387
    • Meldrum, B.1    Garthwaite, J.2
  • 58
    • 0024371893 scopus 로고
    • Photothrombosis-induced ischemic neuronal degeneration in the rat retina
    • Mosinger J. L. and Olney J. W. (1989) Photothrombosis-induced ischemic neuronal degeneration in the rat retina. Exp. Neurol. 105, 110-113.
    • (1989) Exp. Neurol. , vol.105 , pp. 110-113
    • Mosinger, J.L.1    Olney, J.W.2
  • 59
    • 0033083559 scopus 로고    scopus 로고
    • Neuronal cell death: A demise with different shapes
    • Nicotera P., Leist M., and Manzo L. (1999) Neuronal cell death: a demise with different shapes. Trends Pharmacol. Sci. 20, 46-51.
    • (1999) Trends Pharmacol. Sci. , vol.20 , pp. 46-51
    • Nicotera, P.1    Leist, M.2    Manzo, L.3
  • 60
    • 0017715452 scopus 로고
    • Ovarian steroid effects on light-induced retinal photoreceptor damage
    • O'Steen W. K. (1977) Ovarian steroid effects on light-induced retinal photoreceptor damage. Exp. Eye Res. 25, 361-369.
    • (1977) Exp. Eye Res. , vol.25 , pp. 361-369
    • O'Steen, W.K.1
  • 61
    • 0030946503 scopus 로고    scopus 로고
    • Mechanisms of cell death induced by the mitochondrial toxin 3-nitropropionic acid: Acute excitotoxic necrosis and delayed apoptosis
    • Pang Z. and Geddes J. W. (1997) Mechanisms of cell death induced by the mitochondrial toxin 3-nitropropionic acid: acute excitotoxic necrosis and delayed apoptosis. J. Neurosci. 17, 3064-3073.
    • (1997) J. Neurosci. , vol.17 , pp. 3064-3073
    • Pang, Z.1    Geddes, J.W.2
  • 62
    • 0024991845 scopus 로고
    • Determination of superoxide dismutase activity by purely chemical system based on NAD(P)H oxidation
    • Packer L. and Glazer A. N., eds, Academic Press, San Diego
    • Paoletti F. and Mocali A. (1990) Determination of superoxide dismutase activity by purely chemical system based on NAD(P)H oxidation, in Methods in Enzymology, Vol. 186 (Packer L. and Glazer A. N., eds), pp. 209-220. Academic Press, San Diego.
    • (1990) Methods in Enzymology , vol.186 , pp. 209-220
    • Paoletti, F.1    Mocali, A.2
  • 63
    • 0028167701 scopus 로고
    • 3α-Hydroxy-5β-pregnan-20-one sulfate: A negative modulator of the NMDA-induced current in cultured neurons
    • Park-Chung M., Wu F. S., and Farb D. H. (1994) 3α-Hydroxy-5β-pregnan-20-one sulfate: a negative modulator of the NMDA-induced current in cultured neurons. Mol. Pharmacol. 46, 146-150.
    • (1994) Mol. Pharmacol. , vol.46 , pp. 146-150
    • Park-Chung, M.1    Wu, F.S.2    Farb, D.H.3
  • 64
    • 0031467726 scopus 로고    scopus 로고
    • Distinct sites for inverse modulation of N-methyl-D-aspartate receptors by sulfate steroids
    • Park-Chung M., Wu F. S., Purdy R. H., Malayev A. A., Gibbs T. T., and Farb D. H. (1997) Distinct sites for inverse modulation of N-methyl-D-aspartate receptors by sulfate steroids. Mol. Pharmacol. 52, 1113-1128.
    • (1997) Mol. Pharmacol. , vol.52 , pp. 1113-1128
    • Park-Chung, M.1    Wu, F.S.2    Purdy, R.H.3    Malayev, A.A.4    Gibbs, T.T.5    Farb, D.H.6
  • 65
  • 66
    • 0029072690 scopus 로고
    • Evidence for apoptotic cell death in Huntington disease and excitotoxic animal models
    • Portera-Cailliau C., Hedreen J. C., Price D. L., and Koliatsos V. E. (1995) Evidence for apoptotic cell death in Huntington disease and excitotoxic animal models. J. Neurosci. 15, 3775-3787.
    • (1995) J. Neurosci. , vol.15 , pp. 3775-3787
    • Portera-Cailliau, C.1    Hedreen, J.C.2    Price, D.L.3    Koliatsos, V.E.4
  • 67
    • 0029081382 scopus 로고
    • Dual effect of lipid peroxidation on the membrane order of retinal cells in culture
    • Rego A. C. and Oliveira C. (1995) Dual effect of lipid peroxidation on the membrane order of retinal cells in culture. Arch. Biochem. Biophys. 721, 127-136.
    • (1995) Arch. Biochem. Biophys. , vol.721 , pp. 127-136
    • Rego, A.C.1    Oliveira, C.2
  • 68
    • 0029064518 scopus 로고
    • Glutamate induces the production of reactive oxygen species in cultured forebrain neurons following NMDA receptor activation
    • Reynolds I. J. and Hastings T. G. (1995) Glutamate induces the production of reactive oxygen species in cultured forebrain neurons following NMDA receptor activation. J. Neurosci. 15, 3318-3327.
    • (1995) J. Neurosci. , vol.15 , pp. 3318-3327
    • Reynolds, I.J.1    Hastings, T.G.2
  • 69
    • 0028860616 scopus 로고
    • Evidence of apoptotic cell death after experimental traumatic brain injury in the rat
    • Rink A., Fung K. M., Trojanowski J. Q., Lee V. M., Neugebauer F., and McIntosh T. K. (1995) Evidence of apoptotic cell death after experimental traumatic brain injury in the rat. Am. J. Pathol. 147, 1575-1583.
    • (1995) Am. J. Pathol. , vol.147 , pp. 1575-1583
    • Rink, A.1    Fung, K.M.2    Trojanowski, J.Q.3    Lee, V.M.4    Neugebauer, F.5    McIntosh, T.K.6
  • 72
    • 0030318063 scopus 로고    scopus 로고
    • Stress glucocorticoids and damage to the nervous system: The current state of confusion
    • Sapolsky R. M. (1996) Stress glucocorticoids and damage to the nervous system: the current state of confusion. Stress 1, 1-19.
    • (1996) Stress , vol.1 , pp. 1-19
    • Sapolsky, R.M.1
  • 73
    • 0030570392 scopus 로고    scopus 로고
    • Estrogen protects primary cortical neurons from glutamate toxicity
    • Singer C. A., Rogers K. L., Strickland T. M., and Dorsa D. M. (1996) Estrogen protects primary cortical neurons from glutamate toxicity. Neurosci. Lett. 212, 13-16.
    • (1996) Neurosci. Lett. , vol.212 , pp. 13-16
    • Singer, C.A.1    Rogers, K.L.2    Strickland, T.M.3    Dorsa, D.M.4
  • 75
    • 12644271203 scopus 로고    scopus 로고
    • Neuroprotective activity of a new class of steroidal inhibitors of the N-methyl-D-aspartate receptor
    • Weaver C. E., Marek P., Park-Chung M., Tam S. W., and Farb D. H. (1997) Neuroprotective activity of a new class of steroidal inhibitors of the N-methyl-D-aspartate receptor. Proc. Natl. Acad. Sci. USA 94, 10450-10454.
    • (1997) Proc. Natl. Acad. Sci. USA , vol.94 , pp. 10450-10454
    • Weaver, C.E.1    Marek, P.2    Park-Chung, M.3    Tam, S.W.4    Farb, D.H.5
  • 78
    • 0030804272 scopus 로고    scopus 로고
    • Activation of CPP32-like caspases contributes to neuronal apoptosis and neurological dysfunction after traumatic brain injury
    • Yakovlev A. G., Knoblach S. M., Fan L., Fox G. B., Goodnight R., and Faden A. (1997) Activation of CPP32-like caspases contributes to neuronal apoptosis and neurological dysfunction after traumatic brain injury. J. Neurosci. 17, 7415-7424.
    • (1997) J. Neurosci. , vol.17 , pp. 7415-7424
    • Yakovlev, A.G.1    Knoblach, S.M.2    Fan, L.3    Fox, G.B.4    Goodnight, R.5    Faden, A.6
  • 79
    • 0024505905 scopus 로고
    • Dextromethorphan protects retina against ischemic injury in vivo
    • Yoon Y. H. and Marmor M. F. (1989) Dextromethorphan protects retina against ischemic injury in vivo. Arch. Ophthalmol. 107, 409-411.
    • (1989) Arch. Ophthalmol. , vol.107 , pp. 409-411
    • Yoon, Y.H.1    Marmor, M.F.2
  • 80
    • 0030437932 scopus 로고    scopus 로고
    • Hypothermia and metabolic stress: Narrowing the cellular site of early neuroprotection
    • Zeevalk G. D. and Nicklas W. J. (1996) Hypothermia and metabolic stress: narrowing the cellular site of early neuroprotection. J. Pharmacol Exp. Ther. 279, 332-339.
    • (1996) J. Pharmacol Exp. Ther. , vol.279 , pp. 332-339
    • Zeevalk, G.D.1    Nicklas, W.J.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.