Technical aspects and clinical impact of hematopoietic progenitor subset quantification

Stem Cells

Volumn 18, Issue 2, 2000, Pages 76-86

  Baech, John ^b   Johnsen, Hans E ^a  

^a UNIVERSITY OF COPENHAGEN   (Denmark)

^b AALBORG UNIVERSITY HOSPITAL   (Denmark)

Author keywords

Adherence molecules; Analysis; CD34; Cytokine receptors; Differentiation antigens; Flow cytometry; Hematopoietic stem cell transplantation; Prediction of engraftment

Indexed keywords

CD34 ANTIGEN; CELL ADHESION MOLECULE; CYTOKINE RECEPTOR; DIFFERENTIATION ANTIGEN; GROWTH FACTOR RECEPTOR;

BLOOD; BONE MARROW; CELL COUNT; CELL LINEAGE; CELL SUBPOPULATION; FLOW CYTOMETRY; HEMATOPOIETIC STEM CELL TRANSPLANTATION; IMMUNOPHENOTYPING; LEUKAPHERESIS; MOLECULAR GENETICS; PREDICTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; REVIEW;

EID: 0034024727     PISSN: 10665099     EISSN: None     Source Type: Journal    
DOI: 10.1634/stemcells.18-2-76     Document Type: Review

References (90)

1. Haas R, Witt B, Mohle R et al. Sustained long-term hematopoiesis after myeloablative therapy with peripheral blood progenitor cell support. Blood 1995;85:3754-3761.
2. Steen R, Tjonnfjord GE, Gaudernack G et al. Differences in the distribution of CD34 epitopes on normal haemopoietic progenitor cells and leukaemic blast cells. Br J Haematol 1996;94:597-605.
3. Sutherland DR, Keating A. The CD34 antigen: structure, biology, and potential clinical applications. J Hematother 1992;1:115-129.
4. Civin CI, Almeida-Porada G, Lee MJ et al. Sustained, retransplantable, multilineage engraftment of highly purified adult human bone marrow stem cells in vivo. Blood 1996;88:4102-4109.
5. Siena S, Bregni M, Brando B et al. Flow cytometry for clinical estimation of circulating hematopoietic progenitors for autologous transplantation in cancer patients. Blood 1991;77:400-409.
6. (+)-cells: correlation to the quantitation of circulating haemopoietic progenitor cells by in vitro colony-assay. Br J Haematol 1991;77:453-459.
7. Weaver CH, Hazelton B, Birch R et al. An analysis of engraftment kinetics as a function of the CD34 content of peripheral blood progenitor cell collections in 692 patients after the administration of myeloablative chemotherapy. Blood 1995;86:3961-3969.
8. + cell enumeration in blood and autografts: report from the third workshop. J Hematother 1999;8:15-28.
9. Knudsen LM, Gaarsdal E, Jensen L et al. Improved priming for mobilization of and optimal timing for harvest of peripheral blood stem cells. J Hematother 1996;5:399-406.
10. + cell counts to guide timing and yield of large-scale collection by leukapheresis. J Hematother 1998;7:45-52.
11. + hematopoietic progenitors and platelet recovery after high dose chemotherapy and peripheral blood stem cell transplantation. Haematologica 1999;84:517-524.
12. + cells mobilized to the peripheral blood during the recovery from cyclophosphamide chemotherapy. Prog Clin Biol Res 1992;377:575-582.
13. + hematopoietic stem cells (see comments). J Hematother 1996;5:227-236.
14. + human hematopoietic progenitor cells. Exp Hematol 1996;24:875-882.
15. Sutherland DR, Marsh JC, Davidson J et al. Differential sensitivity of CD34 epitopes to cleavage by Pasteurella haemolytica glycoprotease: implications for purification of CD34-positive progenitor cells. Exp Hematol 1992;20:590-599.
16. + human marrow cells that express low levels of Kit protein are enriched for long-term marrow-engrafting cells. Blood 1996;87:4136-4142.
17. Voura EB, Billia F, Iscove NN et al. Expression mapping of adhesion receptor genes during differentiation of individual hematopoietic precursors. Exp Hematol 1997;25:1172-1179.
18. Krause DS, Fackler MJ, Civin CI et al. CD34: structure, biology, and clinical utility. Blood 1996;87:1-13.
19. Civin CI, Strauss LC, Brovall C et al. Antigenic analysis of hematopoiesis. III. A hematopoietic progenitor cell surface antigen defined by a monoclonal antibody raised against KG-1a cells. J Immunol 1984;133:157-165.
20. Inaba T, Shimazaki C, Ashihara E et al. Two-color flow cytometric analysis of CD34-positive peripheral blood stem cells mobilized by recombinant human granulocyte-colony stimulating factor for autotransplantation. Prog Clin Biol Res 1992;377:561-567.
21. Read EJ, O'Shaughnessy JA, Yu MY et al. Flow cytometric quantitation of circulating hematopoietic progenitor cells in breast cancer patients on chemotherapy. Prog Clin Biol Res 1992;377:523-530.
22. Bender JG, Williams SF, Myers S et al. Characterization of chemotherapy mobilized peripheral blood progenitor cells for use in autologous stem cell transplantation. Bone Marrow Transplant 1992;10:281-285.
23. Sovalat H, Wunder E, Tienhaara A et al. Commentary: prospects for standardization of stem cell determination within Europe. J Hematother 1993;2:293-296.
24. + peripheral blood hematopoietic progenitors for autografting in cancer patients. Int J Artif Organs 1993;16(suppl 5):80-82.
25. + cell enumeration in blood and leukapheresis products: report from the second Nordic Workshop. Nordic Stem Cell Laboratory Group (NSCL-G). J Hematother 1996;5:237-245.
26. + cells that lack detectable T cell, B cell, and myeloid cell antigens produce multiple colony-forming cells when cultured with marrow stromal cells. J Exp Med 1990;172:355-358.
27. Galy A, Travis M, Cen D et al. Human T, B, natural killer, and dendritic cells arise from a common bone marrow progenitor cell subset. Immunity 1995;3:459-473.
28. - progenitor cells. Blood 1991;77:1218-1227.
29. - progenitor cells in long-term cultures and semisolid assays. Blood 1993;81:2916-2924.
30. + cells in serum-free cultures initiated with highly purified progenitor cells from human bone marrow. J Exp Med 1992;175:1501-1509.
31. Brandt J, Baird N, Lu L et al. Characterization of a human hematopoietic progenitor cell capable of forming blast cell containing colonies in vitro. J Clin Invest 1988;82:1017-1027.
32. Sutherland HJ, Eaves CJ, Eaves AC et al. Characterization and partial purification of human marrow cells capable of initiating long-term hematopoiesis in vitro. Blood 1989;74:1563-1570.
33. Verfaillie C, Blakolmer K, McGlave P. Purified primitive human hematopoietic progenitor cells with long-term in vitro repopulating capacity adhere selectively to irradiated bone marrow stroma. J Exp Med 1990;172:509-512.
34. Baum CM, Weissman IL, Tsukamoto AS et al. Isolation of a candidate human hematopoietic stem-cell population. Proc Natl Acad Sci USA 1992;89:2804-2808.
35. Shibagaki T, Inoue T, Kubota N et al. Fraction of pluripotent hemopoietic stem cells in DNA synthesis varies with generation age. Exp Hematol 1986;14:794-797.
36. Chaudhary PM, Roninson IB. Expression and activity of P-glycoprotein, a multidrug efflux pump, in human hematopoietic stem cells. Cell 1991;66:85-94.
37. Zijlmans JM, Visser JW, Kleiverda K et al. Modification of rhodamine staining allows identification of hematopoietic stem cells with preferential short-term or long-term bone marrow-repopulating ability. Proc Natl Acad Sci USA 1995;92:8901-8905.
38. + peripheral blood cells from healthy adults mobilized by recombinant human granulocyte colony-stimulating factor. Blood 1994;84:2795-2801.
39. Fritsch G, Emminger W, Buchinger P et al. CD34 analysis in peripheral blood correlates with colony forming capacity - an update. Prog Clin Biol Res 1992;377:531-536.
40. Ravagnani F, Siena S, Bregni M et al. Methodologies to estimate circulating hematopoietic progenitors for autologous transplantation in cancer patients. Haematologica 1991;76(suppl 1):46-49.
41. Wunder E, Sovalat H, Henon P et al., eds. Hematopoietic Stem Cells. The Mulhouse Manual. Dayton, OH: AlphaMed Press, 1994;1-317.
42. Wunder E, Sovalat H, Fritsch G et al. Report on the European workshop on peripheral blood stem cell determination and standardization - Mulhouse, France, February 6-8 and 14-15, 1992. J Hematother 1992;1:131-142.
43. + cell determination by flow cytometry. International Society of Hematotherapy and Graft Engineering. J Hematother 1996;5:213-226.
44. Serke S, Arseniev L, Watts M et al. Imprecision of counting CFU-GM colonies and CD34-expressing cells. Bone Marrow Transplant 1997;20:57-61.
45. + cells be analysed? A study of three classes of antibody and five leucocyte preparation procedures. J Immunol Methods 1997;204:175-188.
46. Lowdell MW, Bainbridge DR. External quality assurance for CD34 cell enumeration - results of a preliminary national trial. Royal Microscopical Society Clinical Flow Cytometry Group QA Schemes. Bone Marrow Transplant 1996;17:849-853.
47. Urashima M, Ohkawara J, Hoshi Y et al. Peripheral blood progenitor cell transplantation estimated by three-colour (CD34, HLA-DR, CD33) flow cytometry. Acta Haematol 1994;92:23-28.
48. Knape CC. Standardization of absolute CD34 cell enumeration (Letter; comment). J Hematother 1996;5:211-212.
49. + cell estimation in leucapheresis products. Bone Marrow Transplant 1996;18:791-796.
50. Remacha AF, Martino R, Sureda A et al. Changes in reticulocyte fractions during peripheral stem cell harvesting: role in monitoring stem cell collection. Bone Marrow Transplant 1996;17:163-168.
51. Zimmerman TM, Lee WJ, Bender JG et al. Quantitative CD34 analysis may be used to guide peripheral blood stem cell harvests. Bone Marrow Transplant 1995;15:439-444.
52. + cells measured under conditions that prevent P-selectin-mediated binding of platelets. Blood 1995;86:3771-3782.
53. Dercksen MW, Rodenhuis S, Dirkson MK et al. Subsets of CD34+ cells and rapid hematopoietic recovery after peripheral-blood stem-cell transplantation. J Clin Oncol 1995;13:1922-1932.
54. + cells from normal human bone marrow, cord blood, peripheral blood, and mobilized peripheral blood from patients undergoing autologous stem cell transplantation. Clin Immunol Immunopathol 1994;70:10-18.
55. To LB, Haylock DN, Simmons PJ et al. The biology and clinical uses of blood stem cells. Blood 1997;89:2233-2258.
56. + hematopoietic progenitor cells. Cytometry 1998;34:264-271.
57. + hematopoietic stem and progenitor cells. European Working Group on Clinical Cell Analysis. Cytometry 1998;34:128-142.
58. + cells predict a rapid platelet recovery after peripheral blood stem cell transplantation. Blood 1995;85:3313-3319.
59. + cells best predict platelet recovery after autologous peripheral blood stem cell transplantation. Bone Marrow Transplant 1998;21:1217-1222.
60. + megakaryocyte progenitor yield and identify patients at risk of delayed platelet engraftment postPBPC transplant. Bone Marrow Transplant 1999;23:539-548.
61. - cells influence days to engraftment and transfusion requirements in autologous blood stem-cell recipients. J Clin Oncol 1998;16:2393-2104.
62. + cells in grafts and time to myeloid and platelet recovery after autologous stem cell transplantation. Exp Hematol 1998;26:10-18.
63. Gonzalez-Requejo A, Madero L, Diaz MA et al. Progenitor cell subsets and engraftment kinetics in children undergoing autologous peripheral blood stem cell transplantation. Br J Haematol 1998;101:104-110.
64. - subsets: collection and engraftment kinetics in autologous peripheral blood stem cells transplantation. Haematologica 1998;83:489-495.
65. + cell dose. Bone Marrow Transplant 1999;23:1237-1243.
66. - cells in early and late trilineage haemopoietic engraftment after autologous blood cell transplantation (see comments). Br J Haematol 1998;103:568-581.
67. - cells in platelet engraftment after intensive therapy for cancer patients given peripheral blood stem cell rescue. Bone Marrow Transplant 1998;22:469-475.
68. + progenitor cells mobilized with chemotherapy and granulocyte colony-stimulating factor. Exp Hematol 1994;22:990-995.
69. Papayannopoulou T, Craddock C. Homing and trafficking of hemopoietic progenitor cells. Acta Haematol 1997;97:97-104.
70. Papayannopoulou T, Priestley GV, Nakamoto B. Anti-VLA4/VCAM-1-induced mobilization requires cooperative signaling through the kit/mkit ligand pathway. Blood 1998;91:2231-2239.
71. + cells. J Hematother 1999;8:539-546.
72. Olweus J, Terstappen LW, Thompson PA et al. Expression and function of receptors for stem cell factor and erythropoietin during lineage commitment of human hematopoietic progenitor cells. Blood 1996;88:1594-1607.
73. Zeigler FC, Bennett BD, Jordan CT et al. Cellular and molecular characterization of the role of the flk-2/flt-3 receptor tyrosine kinase in hematopoietic stem cells. Blood 1994;84:2422-2430.
74. Moore KA, Pytowski B, Witte L et al. Hematopoietic activity of a stromal cell transmembrane protein containing epidermal growth factor-like repeat motifs. Proc Natl Acad Sci USA 1997;94:4011-4016.
75. McKinstry WJ. Li CL, Rasko JE et al. Cytokine receptor expression on hematopoietic stem and progenitor cells. Blood 1997;89:65-71.
76. Shimoda K, Okamura S, Harada N et al. High-frequency granuloid colony-forming ability of G-CSF receptor possessing CD34 antigen positive human umbilical cord blood hematopoietic progenitors. Exp Hematol 1995;23:226-228.
77. Nichol JL, Hokom MM, Hornkohl A et al. Megakaryocyte growth and development factor. Analyses of in vitro effects on human megakaryopoiesis and endogenous serum levels during chemotherapy-induced thrombocytopenia. J Clin Invest 1995;95:2973-2978.
78. Solar GP, Kerr WG, Zeigler FC et al. Role of c-mpl in early hematopoiesis. Blood 1998;92:4-10.
79. Rasmussen T, Honoré L, Johnsen HE. Identification and characterisation of malignant cells using RT-PCR on single flow-sorted cells. Med Oncol 1998;15:96-102.
80. Rasmussen T, Jensen L, Honoré L et al. Circulating clonal cells in multiple myeloma do not express CD34 mRNA, as measured by single-cell and real-time RT-PCR assays. Br J Haematol 1999;107:818-824.
81. - stem cells in fetal sheep. Exp Hematol 1996;24:795-806.
82. DiGiusto D, Chen S, Combs J et al. Human fetal bone marrow early progenitors for T, B, and myeloid cells are found exclusively in the population expressing high levels of CD34. Blood 1994;84:421-432.
83. Knudsen LM, Rasmussen T, Jensen L et al. Reduced bone marrow stem cell pool and progenitor mobilization in multiple myeloma after melphalan treatment. Med Oncol 1999;16:245-254.
84. Osawa M, Hanada K, Hamada H et al. Long-term lymphohematopoietic reconstitution by a single CD34-low/negative hematopoietic stem cell. Science 1996;273:242-245.
85. Goodell MA, Rosenzweig M, Kim H et al. Dye efflux studies suggest that hematopoietic stem cells expressing low or undetectable levels of CD34 antigen exist in multiple species. Nat Med 1997;3:1337-1345.
86. + bone marrow cells. Exp Hematol 1998;26:440-448.
87. + cells [see comments]. Exp Hematol 1998;26:353-360.
88. Bhatia M, Bonnet D, Dick JE. Identification of a novel CD34 negative population of primitive human hematopoietic cells capable of repopulating NOD/SCID mice. Blood 1997;90:1134a.
89. Larsson K, Bjorkstrand B, Ljungman P. Faster engraftment but no reduction in infectious complications after peripheral blood stem cell transplantation compared to autologous bone marrow transplantation. Support Care Cancer 1998;6:378-383.
90. Schiødt I, Bergman OJ, Johnsen HE et al. Early infections after autologous transplantation for haematological malignancies. Med Oncol 1998;15:103-108.