Depletion of CD4+ or CD8+ T-cells prevents Plasmodium berghei induced cerebral malaria in end-stage disease

Parasitology

Volumn 114, Issue 1, 1997, Pages 7-12

  Hermsen, C ^a   Van De Wiel, T ^a   Mommers, E ^a   Sauerwein, R ^a   Eling, W ^a  

^a RADBOUD UNIVERSITY NIJMEGEN   (Netherlands)

Author keywords

blood brain barrier; CD4; CD8; cerebral malaria; Plasmodium berghei; protection

Indexed keywords

CD4 ANTIGEN; CD8 ANTIGEN; MONOCLONAL ANTIBODY;

ANIMAL EXPERIMENT; ARTICLE; BRAIN MALARIA; CONTROLLED STUDY; DISEASE COURSE; HOST PARASITE INTERACTION; MALARIA; MOUSE; NONHUMAN; PLASMODIUM BERGHEI; PRIORITY JOURNAL; T LYMPHOCYTE;

ANIMALS; ANTIBODIES, MONOCLONAL; CD4-POSITIVE T-LYMPHOCYTES; CD8-POSITIVE T-LYMPHOCYTES; DISEASE MODELS, ANIMAL; MALARIA, CEREBRAL; MICE; MICE, INBRED C57BL; PARASITEMIA; PLASMODIUM BERGHEI; SPECIFIC PATHOGEN-FREE ORGANISMS; THYMECTOMY;

EID: 0031025602     PISSN: 00311820     EISSN: None     Source Type: Journal    
DOI: 10.1017/S0031182096008293     Document Type: Article

References (21)

1. CURFS, J. H. A. J., SCHETTERS, T. P. M., HERMSEN, C. C., JERUSALEM, C. R., VAN ZON, A. A. J. C. & ELING, W. M. C. (1989). Immunological aspects of cerebral lesions in murine malaria. Clinical and Experimental Immunology 75, 136-140.
2. CURFS, J. H. A. J., HERMSEN, C. C., MEUWISSEN, J. H. E. TH. & ELING, W. M. C. (1992). Immunization against cerebral pathology in Plasmodium berghei-infected mice. Parasitology 105, 7-14.
3. ECKWALANGA, M., MARUSSIG, M., TAVARES, M. D., BOUANGA, J. C., HULIER, E., PAVLOVITCH, J. H., MINOPRIO, P., PORTNOI, D., RENIA, L. & MAZIER, D. (1994). Murine AIDS protects mice against experimental cerebral malaria: down-regulation by interleukin 10 of a T-helper type 1 CD4+ cell-mediated pathology. Proceedings of the National Academy of Sciences, USA 91, 8097-8101.
4. ELING, W. M. C. & KREMSNER, P. G. (1994). Cytokines in malaria, pathology and protection. Biotherapy 7, 211-221.
5. ELING, W. M. C. & SAUERWEIN, R. (1995). Severe and cerebral malaria: common or distinct pathophysiology ? Reviews in Medical Microbiology 6, 17-25.
6. GRAU, G. E., PIGUET, P. F., ENGERS, H. D., LOUIS, J. A., VASSALLI, P. & LAMBERT, P. H. (1986). L3T4 T-lymphocytes play a major role in the pathogenesis of murine cerebral malaria. Journal of Immunology 137, 2348-2354.
7. HANCOCK, W. W., ADAMS, D. H., WYNER, L. R., SAYEGH, M. H. & KARNOVSKY, M. J. (1994). CD4+ Mononuclear cells induce cytokine expression, vascular smooth muscle cell proliferation, and arterial occlusion after endothelial injury. American Journal of Pathology 145, 1008-1014.
8. HUDSON, L. & HAY, F. (1989). Practical Immunology. Blackwell Scientific, London.
9. IMAI, Y. & KAMIYAMA, T. (1994). T-lymphocytedependent development of cerebral symptoms in WM/Ms rats infected with Plasmodium berghei. Annals of Tropical Medicine and Parasitology 88, 83-85.
10. NEILL, A. L. & HUNT, N. H. (1992). Pathology of fatal and resolving Plasmodium berghei cerebral malaria in mice. Parasitology 105, 165-175.
11. PATNAIK, J. K., DAS, B. S., MISHRA, S. K., MOHANTY, S., SATPATHY, S. K. & MOHANTY, D. (1994). Vascular clogging, mononuclear cell migration, and enhanced vascular permeability in the pathogenesis of human cerebral malaria. American Journal of Tropical Medicine and Hygiene 51, 642-647.
12. POLDER, T. W. (1989). Ph.D. Dissertation: Morphology of cerebral malaria clinical and experimental study.
13. POLDER, T. W., ELINC, W. M., KUBAT, K. & JERUSALEM, C. R. (1988). Histochemistry of cerebral lesions in mice infected with Plasmodium berghei. Tropical Medicine and Parasitology 39, 277-283.
14. POLDER, T. W., ELING, W. M. C., CURFS, J. H. A. J., JERUSALEM, C. R. & WIJERS-ROUW, M. (1992). Ultrastructural changes in the blood- brain barrier of mice infected with Plasmodium berghei. Acta Leidensia 60, 31-4-6.
15. PORTA, J., CAROTA, A., PIZZOLATA, G. P., WILDI, E., WIDMER, M. C., MARGAIRRAZ, C. & GRAU, G. E. (1993). Immunopathological changes in human cerebral malaria. Clinical Neuropathology 12, 142-146.
16. REST, J. R. (1982). Cerebral malaria in inbred mice. A new model and its pathology. Transactions of the Royal Society of Tropical Medicine and Hygiene 76, 410-415.
17. REST, J. R. & WRIGHT, D. H. (1979). Electron microscopy of cerebral malaria in golden hamsters (Mesocricetus auratus). Journal of Pathology 127, 115-120.
18. THUMWOOD, C. M., HUNT, N. H., CLARK, I. A. & COWDEN, W. B. (1988). Breakdown of the blood-brain barrier in murine cerebral malaria. Parasitology 96, 579-589.
19. WAKI, S., UEHARA, K., KANBE, K., ONO, K., SUZUKI, M. & NARIU-CHI, H. (1992). The role of T-cells in pathogenesis and protective immunity to murine malaria. Immunology 75, 646-651.
20. WARUIRI, C. M., NEWTON, C. R. J. C., FORSTER, D., NEW, L., WINSTANLEY, R., MWANGI, I., MARSH, V., WINSTANLEY, M., SNOW, R. W. & MARSH, K. (1996). Epileptic seizures and malaria in Kenyan children. Transactions of the Royal Society of Tropical Medicine and Hygiene 90, 152-155.
21. WRIGHT, D. H., MASEMBE, R. M. & BAZIRA, E. R. (1971). The effect of anti-thymocyte serum on golden hamsters and rats infected with P. berghei. British journal of Experimental Pathology 52, 465-477.