Unscheduled re-entry into the cell cycle induced by NGF precedes cell death in nascent retinal neurones

Journal of Cell Science

Volumn 113, Issue 7, 2000, Pages 1139-1148

  Frade, José María ^a  

^a INSTITUTO CAJAL   (Spain)

Author keywords

Cell cycle; Cyclin B2; Nerve growth factor; Neuronal apoptosis; Neurotrophin receptor p75

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR; CYCLIN B; CYCLIN D1; CYCLIN DEPENDENT KINASE INHIBITOR; NERVE GROWTH FACTOR; ROSCOVITINE;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL CYCLE; CONTROLLED STUDY; EMBRYO; MITOSIS; NERVE CELL CULTURE; NERVE CELL NECROSIS; NONHUMAN; PRIORITY JOURNAL; RETINA GANGLION CELL;

ANIMALS; APOPTOSIS; BRAIN-DERIVED NEUROTROPHIC FACTOR; CELL CYCLE; CELL DEATH; CELL DIFFERENTIATION; CELLS, CULTURED; CHICK EMBRYO; CULTURE MEDIA, CONDITIONED; GROWTH INHIBITORS; INSULIN; NERVE GROWTH FACTOR; NEURONS; NEUROTROPHIN 3; PURINES; RETINA;

ANIMALIA;

EID: 0034014639     PISSN: 00219533     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (16)

1. Aloyz, R. S., Bamji, S. X., Pozniak, C. D., Toma, J. G., Atwal, J., Kaplan, D. R. and Miller, F. D. (1998). p53 is essential for developmental neuron death as regulated by the TrkA and p75 neurotrophin receptors. J. Cell Biol. 143, 1691-1703.
2. Bamji, S. X., Majdan, M., Pozniak, C. D., Belliveau, D. J., Aloyz, R., Kohn, J., Causing, C. G. and Miller, F. D. (1998). The p75 neurotrophin receptor mediates neuronal apoptosis and is essential for naturally occurring sympathetic neuron death. J. Cell. Biol. 140, 911-923.
3. Bottenstein, J. and Sato, G. H. (1979). Growth of a rat neuroblastoma cell line in a serum-free supplemented medium. Proc. Natl. Acad. Sci. USA 76, 514-517.
4. Carter, B. D., Kaltschmidt, C., Kaltschmidt, B., Offenhäuser, N., Böhm-Matthaei, R., Bauerle, P. A. and Barde, Y.-A. (1996). Selective activation of NF-κB by nerve growth factor through the neurotrophin receptor p75. Science 272, 542-545.
5. Casaccia-Bonnefil, P., Carter, B. D., Dobrowsky, R. T. and Chao, M. V. (1996). Death of oligodendrocytes mediated by the interaction of nerve growth factor with its receptor p75. Nature 383, 716-719.
6. Casaccia-Bonnefil, P., Gu, C., Khursigara, G. and Chao, M. V. (1999). The p75 neurotrophin receptor as a modulator of survival and death decisions. Micr. Res. Tech. 45, 217-224.
7. Clarke, A., Maandag, E., van Roon, M., van der Lugt, N., van der Valk, M., Hooper, M., Berns, A. and te Riele, H. (1992). Requirement for a functional Rb-1 gene in murine development. Nature 359, 328-330.
8. Collins, F. (1978). Axon initiation by ciliary neurons in culture. Dev. Biol. 65, 50-57.
9. Davey, F. and Davies, A. M. (1998). TrkB signalling inhibits p75-mediated apoptosis induced by nerve growth factor in embryonic proprioceptive neurons. Curr. Biol. 8, 915-918.
10. de Azeredo, W. F., Leclerc, S., Meijer, L., Havlicek, L., Strnad, M. and Kim, S. H. (1997). Inhibition of cyclin-dependent kinases by purine analogues: crystal structure of human cdk2 complexed with roscovitine. Eur. J. Biochem. 243, 518-526.
11. de la Rosa, E. J., Arribas, A., Frade, J. M. and Rodríguez-Tébar, A. (1994). Role of neurotrophins in the control of neural development: neurotrophin 3 promotes both neuron differentiation and survival of cultured chick retinal cells. Neurosci. 58, 347-352.
12. NTR with Trk receptors. J. Biol. Chem. 270, 22135-22142.
13. Dobrowsky, R. T., Werner, M. H., Castellino A. M., Chao, M. V. and Hannun, Y. A. (1994). Activation of the sphingomyelin cycle through the low-affinity neurotrophin receptor. Science 265, 1596-1599.
14. ElShamy, W. M., Fridvall, L. K. and Ernfors, P. (1998). Growth arrest failure, G1 restriction point override, and S phase death of sensory precursor cells in the absence of neurotrophin-3. Neuron 21, 1003-1015.
15. CDC2 and mitotic cyclin expression in the developing quail neuroretina. Int. J. Dev. Biol. 41, 469-476.
16. Zhang, Q., Ahuja, H. S., Zakeri, Z. F. and Wolgemuth, D. J. (1997). Cyclin-dependent kinase 5 is associated with apoptotic cell death during development and tissue remodeling. Dev. Biol. 183, 222-233.