Substrate specificity of bovine cathepsin B and its inhibition by CA074, based on crystal structure refinement of the complex

Journal of Biochemistry

Volumn 127, Issue 4, 2000, Pages 635-643

  Yamamoto, Atsushi ^a   Tomoo, Koji ^a   Hara, Tadaoki ^a   Murata, Mitsuo ^b   Kitamura, Kunihiro ^b   Ishida, Toshimasa ^a  

^a OSAKA MEDICAL COLLEGE   (Japan)

^b TAISHO PHARMACEUTICAL CO LTD   (Japan)

Author keywords

Binding mode; CA074; Cathepsin B; Substrate specificity; Tertiary structure; X ray crystal structure

Indexed keywords

CA 074; CATHEPSIN B; CATHEPSIN B INHIBITOR; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CATTLE; COVALENT BOND; CRYSTAL STRUCTURE; ENZYME INHIBITOR COMPLEX; ENZYME SPECIFICITY; ENZYME SUBSTRATE COMPLEX; NONHUMAN; X RAY DIFFRACTION;

ANIMALIA; BOS TAURUS; BOVINAE;

EID: 0034007762     PISSN: 0021924X     EISSN: None     Source Type: Journal    
DOI: 10.1093/oxfordjournals.jbchem.a022651     Document Type: Article

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