Phenyl β-methoxyacrylates: A new antimalarial pharmacophore

Journal of Medicinal Chemistry

Volumn 43, Issue 4, 2000, Pages 560-568

  Alzeer, Jawad ^a   Chollet, Jacques ^a   Heinze Krauss, Ingrid ^a   Hubschwerlen, Christian ^a   Matile, Hugues ^a   Ridley, Robert G ^a,b  

^a F HOFFMANN LA ROCHE LTD   (Switzerland)

^b WORLD HEALTH ORGANIZATION   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIMALARIAL AGENT; ATOVAQUONE; CHLOROQUINE; METHYL 3 METHOXY 2 [(2 TRIFLUOROMETHYLPHENYLSULFANYLMETHYL)PHENYL]ACRYLIC ACID; PHENYL BETA METHOXYACRYLIC ACID; UNCLASSIFIED DRUG;

ANIMAL MODEL; ANTIMALARIAL ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG POTENCY; DRUG STRUCTURE; MALARIA; MOUSE; NONHUMAN; PHARMACOPHORE; PLASMODIUM FALCIPARUM; STRUCTURE ACTIVITY RELATION;

ACRYLATES; ADMINISTRATION, CUTANEOUS; ADMINISTRATION, ORAL; ANIMALS; ANTIMALARIALS; BENZENE DERIVATIVES; ERYTHROCYTES; MALARIA; MALE; MICE; PLASMODIUM BERGHEI; PLASMODIUM FALCIPARUM; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0034003128     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm990002y     Document Type: Article

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