메뉴 건너뛰기




Volumn 10, Issue 1, 2000, Pages 39-49

Design and preparation of gadolinium-loaded chitosan particles for cancer neutron capture therapy

Author keywords

Chitosan; Coalescence; Cross linking agent; Emulsion; Gadolinium; Gadopentetic acid; Microparticle; Microsphere; Nanoparticle; Neutron capture therapy

Indexed keywords

CHITOSAN; GADOLINIUM;

EID: 0034003037     PISSN: 11571489     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review
Times cited : (15)

References (66)
  • 1
    • 0028307893 scopus 로고
    • Boron neutron capture therapy of primary and metastatic brain tumors
    • BARTH R.F. and SOLOWAY A.H. - Boron neutron capture therapy of primary and metastatic brain tumors. - Mol. Chem. Neuropathol., 21, 139-154, 1994.
    • (1994) Mol. Chem. Neuropathol. , vol.21 , pp. 139-154
    • Barth, R.F.1    Soloway, A.H.2
  • 2
    • 0025022471 scopus 로고
    • Boron neutron capture therapy of cancer
    • BARTH R.F., SOLOWAY A.H. and FAIRCHILD R.G. - Boron neutron capture therapy of cancer. - Cancer Res., 50, 1061-1070, 1990.
    • (1990) Cancer Res. , vol.50 , pp. 1061-1070
    • Barth, R.F.1    Soloway, A.H.2    Fairchild, R.G.3
  • 3
    • 0005616313 scopus 로고
    • Boron neutron capture therapy for tumors
    • H. Hatanaka Ed., Nishimura, Niigata
    • HATANAKA H. - Boron neutron capture therapy for tumors - In: Boron Neutron Capture Therapy for Tumors, H. Hatanaka Ed., Nishimura, Niigata, 1986, pp. 1-28.
    • (1986) Boron Neutron Capture Therapy for Tumors , pp. 1-28
    • Hatanaka, H.1
  • 6
    • 0024565926 scopus 로고
    • Evaluation of gadolinium-157 as a neutron capture therapy agent
    • BRUGGER R.M. and SHIH J.A. - Evaluation of gadolinium-157 as a neutron capture therapy agent. - Strahlenther. Onkol., 165, 153-156, 1989.
    • (1989) Strahlenther. Onkol. , vol.165 , pp. 153-156
    • Brugger, R.M.1    Shih, J.A.2
  • 9
    • 0026769621 scopus 로고
    • Gadolinium as a neutron capture therapy agent
    • SHIH J.A. and BRUGGER R. - Gadolinium as a neutron capture therapy agent. - Med. Phys., 19, 733-744, 1992.
    • (1992) Med. Phys. , vol.19 , pp. 733-744
    • Shih, J.A.1    Brugger, R.2
  • 11
    • 0033027441 scopus 로고    scopus 로고
    • Gadolinium neutron capture therapy (GdNCT) of melanoma cells and solid tumors with the magnetic resonance imaging contrast agent Gadobutrol
    • HOFMANN B., FISCHER C.-O., LAWACZECK R., PLATZEK J. and SEMMLER W. - Gadolinium neutron capture therapy (GdNCT) of melanoma cells and solid tumors with the magnetic resonance imaging contrast agent Gadobutrol. - Invest. Radiol., 34, 126-133, 1999.
    • (1999) Invest. Radiol. , vol.34 , pp. 126-133
    • Hofmann, B.1    Fischer, C.-O.2    Lawaczeck, R.3    Platzek, J.4    Semmler, W.5
  • 13
    • 0008963791 scopus 로고    scopus 로고
    • Gadolinium neutron capture therapy (GdNCT) with MRI contrast media. In vitro study
    • Y. Mishima Ed., Plenum Press, New York
    • LAWACZECK R., FISCHER C.-O., KRÜGER U., LEUTHER W. and MENRAD J. - Gadolinium neutron capture therapy (GdNCT) with MRI contrast media. In vitro study. - In: Cancer Neutron Capture Therapy, Y. Mishima Ed., Plenum Press, New York, 1996, pp. 859-864.
    • (1996) Cancer Neutron Capture Therapy , pp. 859-864
    • Lawaczeck, R.1    Fischer, C.-O.2    Krüger, U.3    Leuther, W.4    Menrad, J.5
  • 15
    • 0027616871 scopus 로고
    • Electron-equivalent dose for the effect of gadolinium neutron capture therapy on the growth of subcutaneously-inoculated Ehrlich tumor cells in mice
    • AKINE Y., TOKITA N., TOKUUYE K., SATOH M., KOBAYASHI T. and KANDA K. - Electron-equivalent dose for the effect of gadolinium neutron capture therapy on the growth of subcutaneously-inoculated Ehrlich tumor cells in mice. - Jpn. J. Clin. Oncol., 23, 145-148, 1993.
    • (1993) Jpn. J. Clin. Oncol. , vol.23 , pp. 145-148
    • Akine, Y.1    Tokita, N.2    Tokuuye, K.3    Satoh, M.4    Kobayashi, T.5    Kanda, K.6
  • 16
    • 0025630467 scopus 로고
    • Radiation effect of gadolinium-neutron capture reactions on survival of Chinese hamster cells
    • AKINE Y., TOKITA N., MATSUMOTO T., OYAMA H., EGAWA S. and AIZAWA O. - Radiation effect of gadolinium-neutron capture reactions on survival of Chinese hamster cells. - Strahlenther. Onkol., 166, 831-833, 1990.
    • (1990) Strahlenther. Onkol. , vol.166 , pp. 831-833
    • Akine, Y.1    Tokita, N.2    Matsumoto, T.3    Oyama, H.4    Egawa, S.5    Aizawa, O.6
  • 18
    • 0026609683 scopus 로고
    • Transport calculations of depth-dose distributions for gadolinium neutron capture therapy
    • MATSUMOTO T. - Transport calculations of depth-dose distributions for gadolinium neutron capture therapy. - Phys. Med. Biol., 37, 155-162, 1992.
    • (1992) Phys. Med. Biol. , vol.37 , pp. 155-162
    • Matsumoto, T.1
  • 19
    • 0027304301 scopus 로고
    • Design and preparation of ethyl cellulose microcapsules of gadopentetate dimeglumine for neutron-capture therapy using the Wurster process
    • FUKUMORI Y., ICHIKAWA H., TOKUMITSU H., MIYAMOTO Y., JONO K., KANAMORI R., AKINE Y. and TOKITA N. - Design and preparation of ethyl cellulose microcapsules of gadopentetate dimeglumine for neutron-capture therapy using the Wurster process. - Chem. Pharm. Bull., 41, 1144-1148, 1993.
    • (1993) Chem. Pharm. Bull. , vol.41 , pp. 1144-1148
    • Fukumori, Y.1    Ichikawa, H.2    Tokumitsu, H.3    Miyamoto, Y.4    Jono, K.5    Kanamori, R.6    Akine, Y.7    Tokita, N.8
  • 21
    • 0031808981 scopus 로고    scopus 로고
    • Properties of a peptide containing DL-lactide/glycolide copolymer nanospheres prepared by novel emulsion solvent diffusion methods
    • KAWASHIMA Y., YAMAMOTO H., TAKEUCHI H., HINO T. and NIWAT. - Properties of a peptide containing DL-lactide/glycolide copolymer nanospheres prepared by novel emulsion solvent diffusion methods. - Eur. J. Pharm. Biopharm., 45, 41-48, 1998.
    • (1998) Eur. J. Pharm. Biopharm. , vol.45 , pp. 41-48
    • Kawashima, Y.1    Yamamoto, H.2    Takeuchi, H.3    Hino, T.4
  • 22
    • 0032472296 scopus 로고    scopus 로고
    • Body distribution of azidothymidine bound to hexyl-cyanoacrylate nanoparticles after IV injection to rats
    • LÖBENBERG R., ARAUJO L., VON BRIESEN H., RODGERS E. and KREUTER J. - Body distribution of azidothymidine bound to hexyl-cyanoacrylate nanoparticles after IV injection to rats. - J. Control. Release, 50, 21-30, 1998.
    • (1998) J. Control. Release , vol.50 , pp. 21-30
    • Löbenberg, R.1    Araujo, L.2    Von Briesen, H.3    Rodgers, E.4    Kreuter, J.5
  • 23
    • 0031238529 scopus 로고    scopus 로고
    • Long circulating biodegradable poly(phosphazene) nanoparticles surface modified with poly(phosphazene)-poly(ethylene oxide) copolymer
    • VANDORPE J., SCHACHT E., DUNN S., HAWLEY A., STOLNIK S., DAVIS S.S., GARNETT M.C., DAVIES M.C. and ILLUM L. - Long circulating biodegradable poly(phosphazene) nanoparticles surface modified with poly(phosphazene)-poly(ethylene oxide) copolymer. - Biomaterials, 18, 1147-1152, 1997.
    • (1997) Biomaterials , vol.18 , pp. 1147-1152
    • Vandorpe, J.1    Schacht, E.2    Dunn, S.3    Hawley, A.4    Stolnik, S.5    Davis, S.S.6    Garnett, M.C.7    Davies, M.C.8    Illum, L.9
  • 24
    • 0342762031 scopus 로고    scopus 로고
    • Solid lipid nanoparticles (SLN) as potential carrier for human use: Interaction with human granulocytes
    • MÜLLER R.H., MAASSEN S., SCHWARZ C. and MEHNERT W. - Solid lipid nanoparticles (SLN) as potential carrier for human use: interaction with human granulocytes. - J. Control.Release, 47, 261-269, 1997.
    • (1997) J. Control. Release , vol.47 , pp. 261-269
    • Müller, R.H.1    Maassen, S.2    Schwarz, C.3    Mehnert, W.4
  • 26
    • 0343026322 scopus 로고    scopus 로고
    • Biodegradable nanoparticles from sustained release formulations to improved site specific drug delivery
    • LEROUX J.-C., ALLÉMANN E., DEJAEGHERE F., DOELKER E. and GURNY R. - Biodegradable nanoparticles from sustained release formulations to improved site specific drug delivery. - J. Control. Release, 39, 339-350, 1996.
    • (1996) J. Control. Release , vol.39 , pp. 339-350
    • Leroux, J.-C.1    Allémann, E.2    Dejaeghere, F.3    Doelker, E.4    Gurny, R.5
  • 27
    • 0029867284 scopus 로고    scopus 로고
    • Albumin nanospheres as carriers for passive drug targeting: An optimized manufacturing technique
    • MÜLLER B.G., LEUENBERGER H. and KISSEL T. - Albumin nanospheres as carriers for passive drug targeting: an optimized manufacturing technique. - Pharm. Res., 13, 32-37, 1996.
    • (1996) Pharm. Res. , vol.13 , pp. 32-37
    • Müller, B.G.1    Leuenberger, H.2    Kissel, T.3
  • 29
    • 0030576591 scopus 로고    scopus 로고
    • Stability of poly (ε caprolacton) nanospheres in sterile aqueous media
    • MASSON V., MAURIN F., DEVISSAGUET J.P. and FESSI H. - Stability of poly (ε caprolacton) nanospheres in sterile aqueous media. - Int. J. Pharm., 139, 113-123, 1996.
    • (1996) Int. J. Pharm. , vol.139 , pp. 113-123
    • Masson, V.1    Maurin, F.2    Devissaguet, J.P.3    Fessi, H.4
  • 30
    • 0029983418 scopus 로고    scopus 로고
    • Pharmacokinetics and Biodistribution of Oligonucleotide absorbed onto poly(isobutylcyanoacrylate) nanoparticles after intravenous administration in mice
    • NAKADA Y., FATTAL E., FOULQUIER M. and COUVREUR P. - Pharmacokinetics and Biodistribution of Oligonucleotide absorbed onto poly(isobutylcyanoacrylate) nanoparticles after intravenous administration in mice. - Pharm. Res., 13, 38-43, 1996.
    • (1996) Pharm. Res. , vol.13 , pp. 38-43
    • Nakada, Y.1    Fattal, E.2    Foulquier, M.3    Couvreur, P.4
  • 32
    • 0029091362 scopus 로고
    • Nonstealth (poly(lactic acid/albumin)) and stealth (poly(lactic acid-polyethylene glycol)) nanoparticles as injectable drug carriers
    • VERRECCHIA T., SPENLEHAUER G., BAZILE D. V., MURRYBRELIER A., ARCHIMBAUD Y. and VEILLARD M. - Nonstealth (poly(lactic acid/albumin)) and stealth (poly(lactic acid-polyethylene glycol)) nanoparticles as injectable drug carriers. - J. Control. Release, 36, 49-61, 1995.
    • (1995) J. Control. Release , vol.36 , pp. 49-61
    • Verrecchia, T.1    Spenlehauer, G.2    Bazile, D.V.3    Murrybrelier, A.4    Archimbaud, Y.5    Veillard, M.6
  • 34
    • 0025180647 scopus 로고
    • In vitro release kinetic pattern of indomethacin from poly (D,L-lactide) nanocapsules
    • AMMOURY N., FESSI H., DEVISSAGUET J.P., PUISIEUX F. and BENITA S. - In vitro release kinetic pattern of indomethacin from poly (D,L-lactide) nanocapsules. - J. Pharm. Sci., 79, 763-767, 1990.
    • (1990) J. Pharm. Sci. , vol.79 , pp. 763-767
    • Ammoury, N.1    Fessi, H.2    Devissaguet, J.P.3    Puisieux, F.4    Benita, S.5
  • 35
    • 0031714427 scopus 로고    scopus 로고
    • Chitosan: A unique polysaccharide for drug delivery
    • FELT O., BURI P. and GURNY R. - Chitosan: a unique polysaccharide for drug delivery. - Drug Dev. Ind. Pharm., 24, 979-993, 1998.
    • (1998) Drug Dev. Ind. Pharm. , vol.24 , pp. 979-993
    • Felt, O.1    Buri, P.2    Gurny, R.3
  • 36
    • 0030779190 scopus 로고    scopus 로고
    • Chitosan and chitosan/ethylene oxide-propylene oxide block copolymer nanoparticles as novel carriers for proteins and vaccines
    • CALVO P., REMUÑAN-LÓPEZ C., VILA-JATO J.L. and ALONSO M.J. - Chitosan and chitosan/ethylene oxide-propylene oxide block copolymer nanoparticles as novel carriers for proteins and vaccines. - Pharm. Res., 14, 1431-1436, 1997.
    • (1997) Pharm. Res. , vol.14 , pp. 1431-1436
    • Calvo, P.1    Remuñan-López, C.2    Vila-Jato, J.L.3    Alonso, M.J.4
  • 37
    • 0029969540 scopus 로고    scopus 로고
    • Preparation and characterization of chitosan microspheres as drug carrier for prednisolone sodium phosphate as model for anti-inflammatory drugs
    • BERTHOLD A., CREMER K. and KREUTER J. - Preparation and characterization of chitosan microspheres as drug carrier for prednisolone sodium phosphate as model for anti-inflammatory drugs. - J. Control. Release, 39, 17-25, 1996.
    • (1996) J. Control. Release , vol.39 , pp. 17-25
    • Berthold, A.1    Cremer, K.2    Kreuter, J.3
  • 39
    • 0024144884 scopus 로고
    • Biocompatibility of chitosan by oral and intravenous administration
    • HIRANO S., SEINO H., AKIYAMA Y. and NONAKA I. - Biocompatibility of chitosan by oral and intravenous administration. - Polym. Eng. Sci., 59, 897-901, 1988.
    • (1988) Polym. Eng. Sci. , vol.59 , pp. 897-901
    • Hirano, S.1    Seino, H.2    Akiyama, Y.3    Nonaka, I.4
  • 41
    • 0026800237 scopus 로고
    • In vitro evaluation of mucoadhesive properties of chitosan and some other natural polymer
    • LEHR C.-M., BOUWSTRA J.A., SCHACHT E.H. and JUNGINGER H.E. - In vitro evaluation of mucoadhesive properties of chitosan and some other natural polymer. - Int. J. Pharm., 78, 43-48, 1992.
    • (1992) Int. J. Pharm. , vol.78 , pp. 43-48
    • Lehr, C.-M.1    Bouwstra, J.A.2    Schacht, E.H.3    Junginger, H.E.4
  • 42
    • 0029395304 scopus 로고
    • Blood compatibility and biodegradability of partially N-acylated chitosan derivatives
    • LEE K.Y., HA W.S., and PARK W.H. - Blood compatibility and biodegradability of partially N-acylated chitosan derivatives. -Biomaterials, 16, 1211-1216, 1995.
    • (1995) Biomaterials , vol.16 , pp. 1211-1216
    • Lee, K.Y.1    Ha, W.S.2    Park, W.H.3
  • 43
    • 0028107180 scopus 로고
    • Enzymatic degradation of chitins and partially deacetylated chitins
    • SHIGEMASA Y., SAITO K., SASHIWA H. and SAIMOTO H. -Enzymatic degradation of chitins and partially deacetylated chitins. - Int. J. Biol. Macromol., 16, 43-49, 1993.
    • (1993) Int. J. Biol. Macromol. , vol.16 , pp. 43-49
    • Shigemasa, Y.1    Saito, K.2    Sashiwa, H.3    Saimoto, H.4
  • 44
    • 0024745220 scopus 로고
    • N-acetylation in chitosan and the rate of its enzymic hydrolysis
    • HIRANO S., TSUCHIDA H. and NAGAO N. - N-acetylation in chitosan and the rate of its enzymic hydrolysis. - Biomaterials, 10, 574-576, 1989.
    • (1989) Biomaterials , vol.10 , pp. 574-576
    • Hirano, S.1    Tsuchida, H.2    Nagao, N.3
  • 45
    • 0019973628 scopus 로고
    • Lysozyme degradation of partially deacetylated chitin, its films and hydrogels
    • PANGBURN S.H., TRESCONY P.V. and HELLER J. - Lysozyme degradation of partially deacetylated chitin, its films and hydrogels. - Biomaterials, 3, 105-108, 1982.
    • (1982) Biomaterials , vol.3 , pp. 105-108
    • Pangburn, S.H.1    Trescony, P.V.2    Heller, J.3
  • 46
    • 0028071051 scopus 로고
    • Effect of chitosan on the permeability of monolayers of intestinal epithelial cells (Caco-2)
    • ARTURSSON P., LINDMARK T., DAVIS S.S. and ILLUM L. -Effect of chitosan on the permeability of monolayers of intestinal epithelial cells (Caco-2). - Pharm. Res., 11, 1358-1361, 1994.
    • (1994) Pharm. Res. , vol.11 , pp. 1358-1361
    • Artursson, P.1    Lindmark, T.2    Davis, S.S.3    Illum, L.4
  • 47
    • 0021324868 scopus 로고
    • Characteristics of gadolinium-DTPA complex: A potential NMR contrast agent
    • WEINMANN H.-J., BRASCH R.C., PRESS W.-R. and WESBEY G.E. - Characteristics of gadolinium-DTPA complex: a potential NMR contrast agent. - Am. J. Rad., 142, 619-624, 1984.
    • (1984) Am. J. Rad. , vol.142 , pp. 619-624
    • Weinmann, H.-J.1    Brasch, R.C.2    Press, W.-R.3    Wesbey, G.E.4
  • 50
    • 0027468519 scopus 로고
    • Release behavior of 5-fluorouracil from chitosan-gel microspheres immobilizing 5-fluorouracil derivative coated with polysaccharides and their cell specific recognition
    • OHYA Y., TAKEI T., KOBAYASHI H. and OUCHI T. - Release behavior of 5-fluorouracil from chitosan-gel microspheres immobilizing 5-fluorouracil derivative coated with polysaccharides and their cell specific recognition. - J. Microencapsulation, 10, 1-9, 1993.
    • (1993) J. Microencapsulation , vol.10 , pp. 1-9
    • Ohya, Y.1    Takei, T.2    Kobayashi, H.3    Ouchi, T.4
  • 51
    • 0028108163 scopus 로고
    • Preparation and evaluation of cross-linked chitosan microspheres containing furosemide
    • AKBUGA J. and DURMAZ G. - Preparation and evaluation of cross-linked chitosan microspheres containing furosemide. -Int. J. Pharm., 111, 217-222, 1994.
    • (1994) Int. J. Pharm. , vol.111 , pp. 217-222
    • Akbuga, J.1    Durmaz, G.2
  • 52
    • 0026543192 scopus 로고
    • Optimized formulation of magnetic chitosan microspheres containing the anticancer agent, oxantrazole
    • HASSAN E.E., PARISH R.C. and GALLO J.M. - Optimized formulation of magnetic chitosan microspheres containing the anticancer agent, oxantrazole. - Pharm. Res., 9, 390-397, 1992.
    • (1992) Pharm. Res. , vol.9 , pp. 390-397
    • Hassan, E.E.1    Parish, R.C.2    Gallo, J.M.3
  • 53
    • 0026530398 scopus 로고
    • Cross-linked chitosan microspheres: Preparation and evaluation as a matrix for the controlled release of pharmaceuticals
    • THANOO B.C., SUNNY M.C. and JAYAKRISHNAN A. - Cross-linked chitosan microspheres: preparation and evaluation as a matrix for the controlled release of pharmaceuticals. - J. Pharm. Pharmacol., 44, 283-286, 1992.
    • (1992) J. Pharm. Pharmacol. , vol.44 , pp. 283-286
    • Thanoo, B.C.1    Sunny, M.C.2    Jayakrishnan, A.3
  • 54
    • 0029329224 scopus 로고
    • Glutaraldehyde cross-linked chitosan microspheres as a long acting biodegradable drug delivery vehicle: Studies on the in vitro release of mitoxantrone and vivo degradation of microspheres in rat muscle
    • JAMEELA S.R. and JAYAKRISHNAN A. - Glutaraldehyde cross-linked chitosan microspheres as a long acting biodegradable drug delivery vehicle: studies on the in vitro release of mitoxantrone and vivo degradation of microspheres in rat muscle. - Biomaterials, 16, 769-775, 1995.
    • (1995) Biomaterials , vol.16 , pp. 769-775
    • Jameela, S.R.1    Jayakrishnan, A.2
  • 55
    • 0031968972 scopus 로고    scopus 로고
    • Preparation and evaluation of glutaraldehyde cross-linked chitosan microspheres as a gadolinium reservoir for neutron-capture therapy
    • SAHA T.K., JONO K., ICHIKAWA H. and FUKUMORI Y. -Preparation and evaluation of glutaraldehyde cross-linked chitosan microspheres as a gadolinium reservoir for neutron-capture therapy. - Chem. Pharm. Bull., 46, 537-539, 1998.
    • (1998) Chem. Pharm. Bull. , vol.46 , pp. 537-539
    • Saha, T.K.1    Jono, K.2    Ichikawa, H.3    Fukumori, Y.4
  • 56
    • 0020405976 scopus 로고
    • Preparation of hydrophilic albumin microspheres using polymeric dispersing agent
    • LONGO W.E., IWATA H., LINDHEIMER T.A. and GOLDBERG E.P. - Preparation of hydrophilic albumin microspheres using polymeric dispersing agent. - J. Pharm. Sci., 71, 1323-1328, 1982.
    • (1982) J. Pharm. Sci. , vol.71 , pp. 1323-1328
    • Longo, W.E.1    Iwata, H.2    Lindheimer, T.A.3    Goldberg, E.P.4
  • 57
    • 0028914645 scopus 로고
    • Bioavailability of theophylline from glutaraldehyde cross-linked casein microspheres in rabbits following oral administration
    • LATHA M.S., RATHINAM K., MOHANAN P.V. and JAYAKRISHNAN A. - Bioavailability of theophylline from glutaraldehyde cross-linked casein microspheres in rabbits following oral administration. - J. Controlled Release, 34, 1-7, 1995.
    • (1995) J. Controlled Release , vol.34 , pp. 1-7
    • Latha, M.S.1    Rathinam, K.2    Mohanan, P.V.3    Jayakrishnan, A.4
  • 58
    • 0033017771 scopus 로고    scopus 로고
    • Preparation of gadopentetate-loaded chitosan microparticles for gadolinium neutron-capture therapy of cancer by a novel emulsion-droplet coalescence technique
    • TOKUMITSU H., ICHIKAWA H., FUKUMORI Y. and BLOCK L.H. - Preparation of gadopentetate-loaded chitosan microparticles for gadolinium neutron-capture therapy of cancer by a novel emulsion-droplet coalescence technique. - Chem. Pharm. Bull., 47, 838-842, 1999.
    • (1999) Chem. Pharm. Bull. , vol.47 , pp. 838-842
    • Tokumitsu, H.1    Ichikawa, H.2    Fukumori, Y.3    Block, L.H.4
  • 59
    • 0033404225 scopus 로고    scopus 로고
    • Chitosan-gadopentetic acid complex nanoparticlesforgadolinium neutron-capture therapy of cancer: Preparation by novel emulsion-droplet coalescence technique and characterization
    • TOKUMITSU H., ICHIKAWA H. and FUKUMORI Y. - Chitosan-gadopentetic acid complex nanoparticlesforgadolinium neutron-capture therapy of cancer: preparation by novel emulsion-droplet coalescence technique and characterization. - Pharm. Res., 16, 1830-1835, 1999.
    • (1999) Pharm. Res. , vol.16 , pp. 1830-1835
    • Tokumitsu, H.1    Ichikawa, H.2    Fukumori, Y.3
  • 60
    • 0020494826 scopus 로고
    • Microanalysis system of ppm-order 10B concentrations in tissue for neutron capture therapy by prompt gamma-ray spectrometry
    • KOBAYASHI T. and KANDA K. - Microanalysis system of ppm-order 10B concentrations in tissue for neutron capture therapy by prompt gamma-ray spectrometry. - Nucl. Instrum. Methods, 204, 525-531, 1983.
    • (1983) Nucl. Instrum. Methods , vol.204 , pp. 525-531
    • Kobayashi, T.1    Kanda, K.2
  • 61
    • 0025342863 scopus 로고
    • In-situ detection of cutaneous melanoma-seeking 10B-dopa analogue
    • HONDA C., MISHIMA Y., ICHIHASHI M. and HATTA S. - In-situ detection of cutaneous melanoma-seeking 10B-dopa analogue. - J. Dermatol. Sci., 1, 23-32, 1990.
    • (1990) J. Dermatol. Sci. , vol.1 , pp. 23-32
    • Honda, C.1    Mishima, Y.2    Ichihashi, M.3    Hatta, S.4
  • 62
    • 0021996928 scopus 로고
    • Albumin microspheres for intra-arterial tumor targeting. I. Pharmaceutical aspects
    • BURGER J.J., TOMLINSON E., MULDER E.M.A. and MCVIE J.G. - Albumin microspheres for intra-arterial tumor targeting. I. Pharmaceutical aspects. - Int. J. Pharm., 23, 333-344, 1985.
    • (1985) Int. J. Pharm. , vol.23 , pp. 333-344
    • Burger, J.J.1    Tomlinson, E.2    Mulder, E.M.A.3    McVie, J.G.4
  • 63
    • 0024692682 scopus 로고
    • Relative biological effectiveness (RBE) of thermal neutron capture therapy of cultured B-16 melanoma cells pre-incubated with 10B-paraboronophenylalanine
    • ICHIHASHI M., SASASE A., HIRAMOTO T., FUNASAKA Y., HATTA S., MISHIMA Y., KOBAYASHI T., FUKUDA H. and YOSHINO K. - Relative biological effectiveness (RBE) of thermal neutron capture therapy of cultured B-16 melanoma cells pre-incubated with 10B-paraboronophenylalanine. - Pigment Cell Res., 2, 325-329, 1989.
    • (1989) Pigment Cell Res. , vol.2 , pp. 325-329
    • Ichihashi, M.1    Sasase, A.2    Hiramoto, T.3    Funasaka, Y.4    Hatta, S.5    Mishima, Y.6    Kobayashi, T.7    Fukuda, H.8    Yoshino, K.9
  • 64
    • 0033995220 scopus 로고    scopus 로고
    • Gadolinium neutron-capture therapy using novel gadopentetic acid-chitosan complex nanoparticles: In vivo growth suppression of experimental melanoma solid tumor
    • in press
    • TOKUMITSU H., HIRATSUKA J., SAKURAI Y., KOBAYASHI T., ICHIKAWA H. and FUKUMORI Y. - Gadolinium neutron-capture therapy using novel gadopentetic acid-chitosan complex nanoparticles: in vivo growth suppression of experimental melanoma solid tumor - Cancer Lett., in press.
    • Cancer Lett.
    • Tokumitsu, H.1    Hiratsuka, J.2    Sakurai, Y.3    Kobayashi, T.4    Ichikawa, H.5    Fukumori, Y.6
  • 65
    • 0026052546 scopus 로고
    • The relative biological effectiveness of 10B-neutron capture therapy for early skin reaction in the hamster
    • HIRATSUKA J., FUKUDA H., KOBAYASHI T., KARASHIMA H., YOSHINO K., IMAJO Y. and MISHIMA Y. - The relative biological effectiveness of 10B-neutron capture therapy for early skin reaction in the hamster. - Radiat. Res., 128, 186-191, 1991.
    • (1991) Radiat. Res. , vol.128 , pp. 186-191
    • Hiratsuka, J.1    Fukuda, H.2    Kobayashi, T.3    Karashima, H.4    Yoshino, K.5    Imajo, Y.6    Mishima, Y.7
  • 66
    • 0000662870 scopus 로고    scopus 로고
    • The upgrade of the heavy water facility of the Kyoto University Reactor for neutron capture therapy
    • B. Larsson et al. Eds., Elsevier Science, Amsterdam
    • KOBAYASHI T., KANDA K., FUJITA Y., SAKURAI Y. and ONO K. - The upgrade of the heavy water facility of the Kyoto University Reactor for neutron capture therapy. - In : Advances in Neutron Capture Therapy Vol. I, B. Larsson et al. Eds., Elsevier Science, Amsterdam, 1997, pp. 321-325.
    • (1997) Advances in Neutron Capture Therapy , vol.1 , pp. 321-325
    • Kobayashi, T.1    Kanda, K.2    Fujita, Y.3    Sakurai, Y.4    Ono, K.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.