Efficient in vitro affinity maturation of phage antibodies using BIAcore guided selections

Human Antibodies

Volumn 7, Issue 3, 1996, Pages 97-105

  Schier, Robert ^a   Marks, James D ^b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b SAN FRANCISCO GENERAL HOSPITAL   (United States)

Author keywords

Affinity maturation; Antibody fragment; BIAcore; C erbB 2; Phage display; Surface plasmon resonance

Indexed keywords

AMINO ACID; ANTIGEN; BACTERIUM ANTIBODY; HYDROCHLORIC ACID; MAGNESIUM CHLORIDE; POLYCLONAL ANTIBODY; TRIETHYLAMINE;

ANTIBODY AFFINITY; ANTIBODY PRODUCTION; ANTIGEN BINDING; ARTICLE; BACTERIOPHAGE; ESCHERICHIA COLI; MATURATION; MUTANT; NONHUMAN; ONCOGENE C ERB; PHAGE DISPLAY; PRIORITY JOURNAL; TOXICITY;

AMINO ACID SEQUENCE; ANTIBODIES, VIRAL; ANTIBODY AFFINITY; BACTERIOPHAGES; ENZYME-LINKED IMMUNOSORBENT ASSAY; IMMUNOGLOBULIN VARIABLE REGION; MOLECULAR SEQUENCE DATA; RECEPTOR, ERBB-2; SPECTRUM ANALYSIS;

EID: 0030485173     PISSN: 10932607     EISSN: 1875869X     Source Type: Journal    
DOI: 10.3233/HAB-1996-7302     Document Type: Article

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