-
1
-
-
0031015772
-
Phase I clinical and pharmacokinetic study of oral carboxyamidotriazole, a signal transduction inhibitor
-
Berlin J, Tutsch KD, Hutson P, Cleary J, Rago RP, Arzoomanian RZ, Alberti D, Feierabend C and Wilding G (1997) Phase I clinical and pharmacokinetic study of oral carboxyamidotriazole, a signal transduction inhibitor. J Clin Oncol 15:781-789.
-
(1997)
J Clin Oncol
, vol.15
, pp. 781-789
-
-
Berlin, J.1
Tutsch, K.D.2
Hutson, P.3
Cleary, J.4
Rago, R.P.5
Arzoomanian, R.Z.6
Alberti, D.7
Feierabend, C.8
Wilding, G.9
-
2
-
-
0024453294
-
Inositol phosphates and cell signaling
-
Berridge MJ and Irvine RF (1989) Inositol phosphates and cell signaling. Nature (Lond) 341:197-205.
-
(1989)
Nature (Lond)
, vol.341
, pp. 197-205
-
-
Berridge, M.J.1
Irvine, R.F.2
-
3
-
-
0029116458
-
Pharmacokinetics of orally administered carboxyamido-triazole, an inhibitor of calcium mediated signal transduction
-
Figg WD, Cole KA, Reed E, Steinberg SM, Piscitelli SC, Davis PA, Soltis MJ, Jacob J, Boudoilas S, Goldspiel B, Sarosy G, Liotta LA and Kohn EC (1995) Pharmacokinetics of orally administered carboxyamido-triazole, an inhibitor of calcium mediated signal transduction. Clin Cancer Res 1:797-803.
-
(1995)
Clin Cancer Res
, vol.1
, pp. 797-803
-
-
Figg, W.D.1
Cole, K.A.2
Reed, E.3
Steinberg, S.M.4
Piscitelli, S.C.5
Davis, P.A.6
Soltis, M.J.7
Jacob, J.8
Boudoilas, S.9
Goldspiel, B.10
Sarosy, G.11
Liotta, L.A.12
Kohn, E.C.13
-
4
-
-
0013943005
-
Tumor behavior in isolated perfuse organs: In vitro growth and metastases of biopsy material in rabbit thyroid and canine intestinal segments
-
Folkman J (1966) Tumor behavior in isolated perfuse organs: In vitro growth and metastases of biopsy material in rabbit thyroid and canine intestinal segments. Ann Surg 164:493-502.
-
(1966)
Ann Surg
, vol.164
, pp. 493-502
-
-
Folkman, J.1
-
5
-
-
85013312416
-
Tumor angiogenesis: Therapeutic implications
-
Folkman J (1971) Tumor angiogenesis: Therapeutic implications. N Engl J Med 285:1182-1186.
-
(1971)
N Engl J Med
, vol.285
, pp. 1182-1186
-
-
Folkman, J.1
-
6
-
-
0032447869
-
Coordinated induction of inducible nitric oxide synthase and GTP-cyclohydrolase I is dependent on inflammatory cytokines and interferon-gamma in HaCaT keratinocytes: Implications for the model of cutaneous wound repair
-
Frank S, Kolb N, Werner ER and Pfeilschifter J (1998) Coordinated induction of inducible nitric oxide synthase and GTP-cyclohydrolase I is dependent on inflammatory cytokines and interferon-gamma in HaCaT keratinocytes: Implications for the model of cutaneous wound repair. J Invest Dermatol 111:1065-1071.
-
(1998)
J Invest Dermatol
, vol.111
, pp. 1065-1071
-
-
Frank, S.1
Kolb, N.2
Werner, E.R.3
Pfeilschifter, J.4
-
7
-
-
0014664384
-
Preservation of vascular integrity in organs perfused in vitro with a platelet-rich medium
-
Gimrone MA Jr, Aster RH and Cotran RS (1969) Preservation of vascular integrity in organs perfused in vitro with a platelet-rich medium. Nature (Lond) 221:33-36.
-
(1969)
Nature (Lond)
, vol.221
, pp. 33-36
-
-
Gimrone M.A., Jr.1
Aster, R.H.2
Cotran, R.S.3
-
8
-
-
0027503305
-
Muscarinic receptor-mediated tyrosine phosphorylation of phospholipase C-gamma
-
Gusovsky F, Lueders JE, Kohn EC and Felder CC (1993) Muscarinic receptor-mediated tyrosine phosphorylation of phospholipase C-gamma. J Biol Chem 268: 7768-7772.
-
(1993)
J Biol Chem
, vol.268
, pp. 7768-7772
-
-
Gusovsky, F.1
Lueders, J.E.2
Kohn, E.C.3
Felder, C.C.4
-
9
-
-
0033052655
-
Increased transcriptional activity of prostate-specific antigen in the presence of TNP-470, an angiogenesis inhibitor
-
Horti J, Dixon SC, Logothetis CJ, Guo Y, Reed E and Figg WD (1999) Increased transcriptional activity of prostate-specific antigen in the presence of TNP-470, an angiogenesis inhibitor. Br J Cancer 79:1588-1593.
-
(1999)
Br J Cancer
, vol.79
, pp. 1588-1593
-
-
Horti, J.1
Dixon, S.C.2
Logothetis, C.J.3
Guo, Y.4
Reed, E.5
Figg, W.D.6
-
10
-
-
0025043173
-
Anti-proliferative activity of L-651,582 correlates with calcium-mediated regulation of nucleotide metabolism at phosphoribosyl pyrophosphate synthetase
-
Hupe DJ, Behrens ND and Boltz R (1990) Anti-proliferative activity of L-651,582 correlates with calcium-mediated regulation of nucleotide metabolism at phosphoribosyl pyrophosphate synthetase. J Cell Physiol 144:457-466.
-
(1990)
J Cell Physiol
, vol.144
, pp. 457-466
-
-
Hupe, D.J.1
Behrens, N.D.2
Boltz, R.3
-
11
-
-
0025912644
-
The inhibition of receptor-mediated and voltage-dependent calcium entry by the antiproliferative L-651,582
-
Hupe DJ, Boltz R, Cohen CJ, Felix J, Ham E, Miller D, Soderman D and Van Skiver D (1991) The inhibition of receptor-mediated and voltage-dependent calcium entry by the antiproliferative L-651,582. J Biol Chem 286:10136-10142.
-
(1991)
J Biol Chem
, vol.286
, pp. 10136-10142
-
-
Hupe, D.J.1
Boltz, R.2
Cohen, C.J.3
Felix, J.4
Ham, E.5
Miller, D.6
Soderman, D.7
Van Skiver, D.8
-
12
-
-
0031048133
-
Inhibitory effects of CAI in glioblastoma growth and invasion
-
Jacobs W, Mikkelsen T, Smith R, Nelson K, Rosenblum ML and Kohn EC (1997) Inhibitory effects of CAI in glioblastoma growth and invasion. J Neuro-Oncol 32:93-101.
-
(1997)
J Neuro-oncol
, vol.32
, pp. 93-101
-
-
Jacobs, W.1
Mikkelsen, T.2
Smith, R.3
Nelson, K.4
Rosenblum, M.L.5
Kohn, E.C.6
-
13
-
-
0023714428
-
Guanine nucleotide-and inositol 1,4,5-trisphosphate-induced calcium release in rabbit main pulmonary artery
-
Kobayashi S, Somlyo AP and Somlyo AV (1988) Guanine nucleotide-and inositol 1,4,5-trisphosphate-induced calcium release in rabbit main pulmonary artery. J Physiol 403:601-619.
-
(1988)
J Physiol
, vol.403
, pp. 601-619
-
-
Kobayashi, S.1
Somlyo, A.P.2
Somlyo, A.V.3
-
14
-
-
0028913347
-
Angiogenesis: Role of calcium-mediated signal transduction
-
Kohn EC, Alessandro R, Spoonster J, Wersto RP and Liotta LA (1995) Angiogenesis: Role of calcium-mediated signal transduction. Proc Natl Acad Sci USA 92:1307-1311.
-
(1995)
Proc Natl Acad Sci USA
, vol.92
, pp. 1307-1311
-
-
Kohn, E.C.1
Alessandro, R.2
Spoonster, J.3
Wersto, R.P.4
Liotta, L.A.5
-
15
-
-
0030991528
-
Phase I trial of micronized formulation carboxyamidotriazole in patients with refractory solid tumors: Pharmacokinetics, clinical outcome, and comparison of formulations
-
Kohn EC, Figg WD, Sarosy GA, Bauer KS, Davis PA, Soltis MJ, Thompkins A, Liotta LA and Reed E (1997). Phase I trial of micronized formulation carboxyamidotriazole in patients with refractory solid tumors: Pharmacokinetics, clinical outcome, and comparison of formulations. J Clin Oncol 15:1985-1993.
-
(1997)
J Clin Oncol
, vol.15
, pp. 1985-1993
-
-
Kohn, E.C.1
Figg, W.D.2
Sarosy, G.A.3
Bauer, K.S.4
Davis, P.A.5
Soltis, M.J.6
Thompkins, A.7
Liotta, L.A.8
Reed, E.9
-
16
-
-
0028040432
-
Calcium influx modulates expression of matrix metalloproteinase-2 (72-kDa type IV collagenase, gelatinase A)
-
Kohn EC, Jacobs W, Kim YS, Alessandro R, Stetler-Stevenson WG and Liotta LA (1994) Calcium influx modulates expression of matrix metalloproteinase-2 (72-kDa type IV collagenase, gelatinase A). J Biol Chem 269:21505-21511.
-
(1994)
J Biol Chem
, vol.269
, pp. 21505-21511
-
-
Kohn, E.C.1
Jacobs, W.2
Kim, Y.S.3
Alessandro, R.4
Stetler-Stevenson, W.G.5
Liotta, L.A.6
-
17
-
-
0025012854
-
L651582: A novel antiproliferative and antimetastasis agent
-
Kohn EC and Liotta LA (1990) L651582: A novel antiproliferative and antimetastasis agent. J Natl Cancer Inst 82:54-60.
-
(1990)
J Natl Cancer Inst
, vol.82
, pp. 54-60
-
-
Kohn, E.C.1
Liotta, L.A.2
-
19
-
-
0030772486
-
Antiproliferative and anti-invasive effects of carboxyamido-triazole on breast cancer cell lines
-
Lambert PA, Somers KD, Kohn EC and Perry RR (1997) Antiproliferative and anti-invasive effects of carboxyamido-triazole on breast cancer cell lines. Surgery 122:372-379.
-
(1997)
Surgery
, vol.122
, pp. 372-379
-
-
Lambert, P.A.1
Somers, K.D.2
Kohn, E.C.3
Perry, R.R.4
-
20
-
-
0023872015
-
Inositol 1,4,5-trisphosphate-induced calcium release and guanine nucleotide-binding protein-mediated periodic calcium rises in golden hamster eggs
-
Miyazaki S (1988). Inositol 1,4,5-trisphosphate-induced calcium release and guanine nucleotide-binding protein-mediated periodic calcium rises in golden hamster eggs. J Cell Biol 106:345-353.
-
(1988)
J Cell Biol
, vol.106
, pp. 345-353
-
-
Miyazaki, S.1
-
21
-
-
0030042761
-
Nitric oxide mediates mitogenic effect of VEGF on coronary endothelium
-
Morbidelli L, Chang C-H, Douglas JG, Granger HJ, Ledda F and Ziche M (1996) Nitric oxide mediates mitogenic effect of VEGF on coronary endothelium. Am Physiol Soc 363:H411-H415.
-
(1996)
Am Physiol Soc
, vol.363
-
-
Morbidelli, L.1
Chang, C.-H.2
Douglas, J.G.3
Granger, H.J.4
Ledda, F.5
Ziche, M.6
-
22
-
-
0030057662
-
Role of intracellular calcium as a priming signal for the induction of nitric oxide synthesis in murine peritoneal macrophages
-
Park YC, Jun CD, Kang HS, Kim HD, Kim HM and Chung HT (1996) Role of intracellular calcium as a priming signal for the induction of nitric oxide synthesis in murine peritoneal macrophages. Immunology 87:296-302.
-
(1996)
Immunology
, vol.87
, pp. 296-302
-
-
Park, Y.C.1
Jun, C.D.2
Kang, H.S.3
Kim, H.D.4
Kim, H.M.5
Chung, H.T.6
-
23
-
-
0022499568
-
Are keratin proteins a better tumor marker than epithelial membrane antigen? a comparative imimmohistochemical study of various paraffin-embedded neoplasms using monoclonal and polyclonal antibodies
-
Pinkus GS, Etheridge CL and O'Connor EM (1986) Are keratin proteins a better tumor marker than epithelial membrane antigen? A comparative imimmohistochemical study of various paraffin-embedded neoplasms using monoclonal and polyclonal antibodies. Am J Clin Pathol 85:269-277.
-
(1986)
Am J Clin Pathol
, vol.85
, pp. 269-277
-
-
Pinkus, G.S.1
Etheridge, C.L.2
O'Connor, E.M.3
-
25
-
-
0032540157
-
Effect of vascular endothelial growth factor on nitric oxide production by cultured rat mesangial cells
-
Trachtman H, Futterweit S, Franki N and Singhal PC (1998) Effect of vascular endothelial growth factor on nitric oxide production by cultured rat mesangial cells. Biochem Biophys Res Commun 245:443-446.
-
(1998)
Biochem Biophys Res Commun
, vol.245
, pp. 443-446
-
-
Trachtman, H.1
Futterweit, S.2
Franki, N.3
Singhal, P.C.4
-
26
-
-
0029819854
-
Effects of the calcium influx inhibitor carboxyamidotriazole on the proliferation and invasiveness of human prostate tumor cell lines
-
Wasilenko WJ, Palad AJ, Somers KD, Blackmore PF, Kohn EC, Rhim JS, Wright GL and Schellhammer PF (1996) Effects of the calcium influx inhibitor carboxyamidotriazole on the proliferation and invasiveness of human prostate tumor cell lines. Intl J Cancer 68:259-264.
-
(1996)
Intl J Cancer
, vol.68
, pp. 259-264
-
-
Wasilenko, W.J.1
Palad, A.J.2
Somers, K.D.3
Blackmore, P.F.4
Kohn, E.C.5
Rhim, J.S.6
Wright, G.L.7
Schellhammer, P.F.8
-
27
-
-
0027717345
-
Tumor angiogenesis correlates with metastasis in invasive prostate carcinoma
-
Weidner N, Carroll PR, Flax J, Blumenfeld W and Folkman J (1993) Tumor angiogenesis correlates with metastasis in invasive prostate carcinoma. Am J Pathol 143:401-409.
-
(1993)
Am J Pathol
, vol.143
, pp. 401-409
-
-
Weidner, N.1
Carroll, P.R.2
Flax, J.3
Blumenfeld, W.4
Folkman, J.5
-
28
-
-
0026083903
-
Tumor angiogenesis and metastasis correlation in invasive breast carcinoma
-
Weidner N, Semple JP, Welch WR and Folkman J (1991) Tumor angiogenesis and metastasis correlation in invasive breast carcinoma. N Engl J Med 324:1-8.
-
(1991)
N Engl J Med
, vol.324
, pp. 1-8
-
-
Weidner, N.1
Semple, J.P.2
Welch, W.R.3
Folkman, J.4
-
29
-
-
0030615095
-
2+-dependent NO-production from central nervous system cells in culture measured by NO-nitrite/ozone chemoluminescence
-
2+-dependent NO-production from central nervous system cells in culture measured by NO-nitrite/ozone chemoluminescence. Brain Res 748:1-11.
-
(1997)
Brain Res
, vol.748
, pp. 1-11
-
-
Weikert, S.1
Freyer, D.2
Weih, M.3
Isaev, N.4
Busch, C.5
Schultze, J.6
Megow, D.7
Dirnagl, U.8
|