Comparison of the mutations at Hprt exon 3 of T-lymphocytes from B6C3F1 mice and F344 rats exposed by inhalation to 1,3-butadiene or the racemic mixture of 1,2:3,4-diepoxybutane

Mutation Research - Genetic Toxicology and Environmental Mutagenesis

Volumn 464, Issue 2, 2000, Pages 169-184

  Meng, Quanxin ^a,b   Singh, Navjot ^a   Heflich, Robert H ^c   Bauer, Michael J ^b   Walker, Vernon E ^a,b  

^a WADSWORTH CENTER   (United States)

^b STATE UNIVERSITY OF NEW YORK   (United States)

^c NATIONAL CENTER FOR TOXICOLOGICAL RESEARCH   (United States)

Author keywords

Butadiene; Diepoxybutane; Hprt; Lymphocytes; Mouse; Mutational spectra; Rat

Indexed keywords

1,3 BUTADIENE; ADENINE; BUTADIENE DIEPOXIDE; CYTOSINE; DNA; GUANINE; THYMINE;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CELL CLONE; CONTROLLED STUDY; EXON; FEMALE; GENE AMPLIFICATION; GENE DELETION; GENOME; INHALATION; METABOLITE; MOUSE; MUTATION; NONHUMAN; NUCLEIC ACID BASE SUBSTITUTION; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; RACEMIC MIXTURE; RAT; SEQUENCE ANALYSIS; SPLEEN CELL; T LYMPHOCYTE;

ADMINISTRATION, INHALATION; ANIMALS; BUTADIENES; CELLS, CULTURED; CROSSES, GENETIC; DNA MUTATIONAL ANALYSIS; EPOXY COMPOUNDS; EXONS; FEMALE; HYPOXANTHINE PHOSPHORIBOSYLTRANSFERASE; MICE; MUTAGENESIS; MUTAGENICITY TESTS; MUTAGENS; MUTATION; POLYMERASE CHAIN REACTION; RATS; RATS, INBRED F344; SPLEEN; T-LYMPHOCYTES;

EID: 0033984222     PISSN: 13835718     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1383-5718(99)00157-6     Document Type: Article

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