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Volumn 76, Issue 4, 2000, Pages 585-595

Activation of p38 mitogen-activated protein kinase and mitochondrial Ca2+-mediated oxidative stress are essential for the enhanced expression of grp78 induced by the protein phosphatase inhibitors okadaic acid and calyculin A

Author keywords

Glucose regulated protein; Mitochondrial calcium; Oxidative stress; p38 mitogen activated protein kinase; Protein phosphatase

Indexed keywords

CALCIUM; CALYCULIN A; CHAPERONE; GLUCOSE REGULATED PROTEIN 78; MITOGEN ACTIVATED PROTEIN KINASE; OKADAIC ACID; UNCLASSIFIED DRUG;

EID: 0033981732     PISSN: 07302312     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-4644(20000315)76:4<585::AID-JCB7>3.0.CO;2-U     Document Type: Article
Times cited : (30)

References (70)
  • 1
    • 0026376827 scopus 로고
    • A binding site for the cyclic adenosine 3′,5′-monophosphate-responsive element-binding protein as a regulatory element in the grp78 promoter
    • Alexandre S, Nakaki T, Vanhamme L, Lee AS. 1991. A binding site for the cyclic adenosine 3′,5′-monophosphate-responsive element-binding protein as a regulatory element in the grp78 promoter. Mol Endocrinol 5:1862-1871.
    • (1991) Mol Endocrinol , vol.5 , pp. 1862-1871
    • Alexandre, S.1    Nakaki, T.2    Vanhamme, L.3    Lee, A.S.4
  • 2
  • 3
    • 0029998621 scopus 로고    scopus 로고
    • The permeability transition pore as a mitochondrial calcium release channel; a critical appraisal
    • Bernardi P, Petronilli V. 1996. The permeability transition pore as a mitochondrial calcium release channel; a critical appraisal. J Bioenerg Biomembr 28:131-138.
    • (1996) J Bioenerg Biomembr , vol.28 , pp. 131-138
    • Bernardi, P.1    Petronilli, V.2
  • 4
    • 0021759404 scopus 로고
    • Pathway for uncoupler-induced calcium efflux in rat liver mitochondria inhibition by ruthenium red
    • Bernardi P, Paradisi V, Pozzan T, Azzone GF. 1984. Pathway for uncoupler-induced calcium efflux in rat liver mitochondria inhibition by ruthenium red. Biochemistry 23:1645-1651.
    • (1984) Biochemistry , vol.23 , pp. 1645-1651
    • Bernardi, P.1    Paradisi, V.2    Pozzan, T.3    Azzone, G.F.4
  • 5
    • 0023691731 scopus 로고
    • Inhibitory effect of a marine-sponge toxin, okadaic acid, on protein phosphatases
    • Bialojan C, Takai A. 1988. Inhibitory effect of a marine-sponge toxin, okadaic acid, on protein phosphatases. Biochem J 256:283-290.
    • (1988) Biochem J , vol.256 , pp. 283-290
    • Bialojan, C.1    Takai, A.2
  • 6
    • 0018837597 scopus 로고
    • Enhancement of hydrogen peroxide formation by protophores and ionophores in antimycin-supplemented mitochondria
    • Cadenas E, Boveris A. 1980. Enhancement of hydrogen peroxide formation by protophores and ionophores in antimycin-supplemented mitochondria. Biochem J 188: 31-37.
    • (1980) Biochem J , vol.188 , pp. 31-37
    • Cadenas, E.1    Boveris, A.2
  • 7
    • 0028926263 scopus 로고
    • Parallel signal processing among mammalian MAPKs
    • Cano E, Mahadevan LC. 1995. Parallel signal processing among mammalian MAPKs. Trends Biochem Sci 20:117-122.
    • (1995) Trends Biochem Sci , vol.20 , pp. 117-122
    • Cano, E.1    Mahadevan, L.C.2
  • 9
    • 0029871793 scopus 로고    scopus 로고
    • Modulation of protein phosphorylation and stress protein expression by okadaic acid on heat shock cells
    • Chen KD, Chu JJ, Lai YK. 1996. Modulation of protein phosphorylation and stress protein expression by okadaic acid on heat shock cells. J Cell Biochem 61:255-265.
    • (1996) J Cell Biochem , vol.61 , pp. 255-265
    • Chen, K.D.1    Chu, J.J.2    Lai, Y.K.3
  • 10
    • 0030837425 scopus 로고    scopus 로고
    • Rapid induction of the grp78 gene by cooperative actions of okadaic acid and heat-shock in 9L rat brain tumor cells. Involvement of a cAMP responsive element-like promoter sequence and a protein kinase A signaling pathway
    • Chen KD, Hung JJ, Huang HL, Chang MDT, Lai YK. 1997. Rapid induction of the grp78 gene by cooperative actions of okadaic acid and heat-shock in 9L rat brain tumor cells. Involvement of a cAMP responsive element-like promoter sequence and a protein kinase A signaling pathway. Eur J Biochem 248:120-129.
    • (1997) Eur J Biochem , vol.248 , pp. 120-129
    • Chen, K.D.1    Hung, J.J.2    Huang, H.L.3    Chang, M.D.T.4    Lai, Y.K.5
  • 11
    • 0031964698 scopus 로고    scopus 로고
    • Involvement of p38 mitogen-activated protein kinase signaling pathway in the rapid induction of the 78-kDa glucose-regulated protein in 9L rat brain tumor cell
    • Chen KD, Chen LY, Huang HL, Lieu CH, Chang YN, Chang MDT, Lai YK. 1998. Involvement of p38 mitogen-activated protein kinase signaling pathway in the rapid induction of the 78-kDa glucose-regulated protein in 9L rat brain tumor cell. J Biol Chem 273:749-755.
    • (1998) J Biol Chem , vol.273 , pp. 749-755
    • Chen, K.D.1    Chen, L.Y.2    Huang, H.L.3    Lieu, C.H.4    Chang, Y.N.5    Chang, M.D.T.6    Lai, Y.K.7
  • 12
    • 0032101138 scopus 로고    scopus 로고
    • Antioxidants reduce cyclooxygenase-2 expression, prostaglandin production, and proliferation in colorectal cancer cells
    • Chinery R, Beauchamp RD, Shyr Y, Kirkland SC, Coffey RJ, Morrow JD. 1998. Antioxidants reduce cyclooxygenase-2 expression, prostaglandin production, and proliferation in colorectal cancer cells. Cancer Res 58:2323-2327.
    • (1998) Cancer Res , vol.58 , pp. 2323-2327
    • Chinery, R.1    Beauchamp, R.D.2    Shyr, Y.3    Kirkland, S.C.4    Coffey, R.J.5    Morrow, J.D.6
  • 13
    • 0023277545 scopus 로고
    • Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction
    • Chomczynski P, Sacchi N. 1987. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal Biochem 162:156-159.
    • (1987) Anal Biochem , vol.162 , pp. 156-159
    • Chomczynski, P.1    Sacchi, N.2
  • 14
    • 0024397415 scopus 로고
    • The structure and regulation of protein phosphatases
    • Cohen P. 1989. The structure and regulation of protein phosphatases. Annu Rev Biochem 58:453-508.
    • (1989) Annu Rev Biochem , vol.58 , pp. 453-508
    • Cohen, P.1
  • 15
    • 0025998844 scopus 로고
    • Classification of protein-serine/threonine phosphatases: Identification and quantitation in cell extracts
    • Cohen P. 1991. Classification of protein-serine/threonine phosphatases: identification and quantitation in cell extracts. Methods Enzymol 201:389-398.
    • (1991) Methods Enzymol , vol.201 , pp. 389-398
    • Cohen, P.1
  • 16
    • 0025181418 scopus 로고
    • Okadaic acid; a new probe for the study of cellular regulation
    • Cohen P, Holmes CF, Tsukitani Y. 1990. Okadaic acid; a new probe for the study of cellular regulation. Trends Biochem Sci 15:98-102.
    • (1990) Trends Biochem Sci , vol.15 , pp. 98-102
    • Cohen, P.1    Holmes, C.F.2    Tsukitani, Y.3
  • 17
    • 0027752355 scopus 로고
    • Important roles for novel protein phosphatases dephosphorylating serine and threonine residues
    • Cohen PT. 1993. Important roles for novel protein phosphatases dephosphorylating serine and threonine residues. Biochem Soc Trans 21:884-888.
    • (1993) Biochem Soc Trans , vol.21 , pp. 884-888
    • Cohen, P.T.1
  • 18
    • 0030747259 scopus 로고    scopus 로고
    • Intracellular calcium chelator BAPTA protects cells against toxic calcium overload but also alters physiological calcium responses
    • Collatz MB, Rudel R, Brinkmeier H. 1997. Intracellular calcium chelator BAPTA protects cells against toxic calcium overload but also alters physiological calcium responses. Cell Calcium 21:453-459.
    • (1997) Cell Calcium , vol.21 , pp. 453-459
    • Collatz, M.B.1    Rudel, R.2    Brinkmeier, H.3
  • 20
    • 0028988138 scopus 로고
    • SB 203580 is a specific inhibitor of a MAP kinase homologue which is stimulated by cellular stresses and interleukin-1
    • Cuenda A, Rouse J, Doza YN, Meier R, Cohen P, Gallagher TF, Young PR, Lee JC. 1995. SB 203580 is a specific inhibitor of a MAP kinase homologue which is stimulated by cellular stresses and interleukin-1. FEBS Lett 364: 229-233.
    • (1995) FEBS Lett , vol.364 , pp. 229-233
    • Cuenda, A.1    Rouse, J.2    Doza, Y.N.3    Meier, R.4    Cohen, P.5    Gallagher, T.F.6    Young, P.R.7    Lee, J.C.8
  • 21
    • 0031943507 scopus 로고    scopus 로고
    • Cell surface localization of the 78 kD glucose regulated protein (GRP78) induced by thapsigargin
    • Delpino A, Piselli R, Vismara D, Vendetti S, Colizzi V. 1998. Cell surface localization of the 78 kD glucose regulated protein (GRP78) induced by thapsigargin. Mol Membr Biol 15:21-26.
    • (1998) Mol Membr Biol , vol.15 , pp. 21-26
    • Delpino, A.1    Piselli, R.2    Vismara, D.3    Vendetti, S.4    Colizzi, V.5
  • 22
    • 0027282996 scopus 로고
    • N-Acetyl-l-cysteine
    • De Vries N, De Flora S. 1993. N-Acetyl-l-cysteine. J Cell Biochem 17F(suppl):270-277.
    • (1993) J Cell Biochem , vol.17 F , Issue.SUPPL. , pp. 270-277
    • De Vries, N.1    De Flora, S.2
  • 24
    • 0023264984 scopus 로고
    • Depletion of intracellular calcium stores by calcium ionophore A23187 induces the genes for glucose-regulated proteins in hamster fibroblasts
    • Drummond IA, Lee AS, Resendez E Jr, Steinhardt RA. 1987. Depletion of intracellular calcium stores by calcium ionophore A23187 induces the genes for glucose-regulated proteins in hamster fibroblasts. J Biol Chem 262:12801-12805.
    • (1987) J Biol Chem , vol.262 , pp. 12801-12805
    • Drummond, I.A.1    Lee, A.S.2    Resendez E., Jr.3    Steinhardt, R.A.4
  • 25
    • 0027080612 scopus 로고
    • Nonphorbol tumor promoters okadaic acid and calyculin-A induce membrane translocation of protein kinase C
    • Gopalakrishna R, Chen ZH, Gundimeda U. 1992. Nonphorbol tumor promoters okadaic acid and calyculin-A induce membrane translocation of protein kinase C. Biochem Biophys Res Commun 189:950-957.
    • (1992) Biochem Biophys Res Commun , vol.189 , pp. 950-957
    • Gopalakrishna, R.1    Chen, Z.H.2    Gundimeda, U.3
  • 26
    • 0028110180 scopus 로고
    • BiP (GRP78), an essential hsp70 resident protein in the endoplasmic reticulum
    • Haas IG. 1994. BiP (GRP78), an essential hsp70 resident protein in the endoplasmic reticulum. Experientia 50: 1012-1020.
    • (1994) Experientia , vol.50 , pp. 1012-1020
    • Haas, I.G.1
  • 27
    • 0027459409 scopus 로고
    • Okadaic acid as an inducer of the 78-kDa glucose-regulated protein in 9L rat brain tumor cells
    • Hou MC, Shen CH, Lee WC, Lai YK. 1993. Okadaic acid as an inducer of the 78-kDa glucose-regulated protein in 9L rat brain tumor cells. J Cell Biochem 51:91-101.
    • (1993) J Cell Biochem , vol.51 , pp. 91-101
    • Hou, M.C.1    Shen, C.H.2    Lee, W.C.3    Lai, Y.K.4
  • 28
    • 0023387898 scopus 로고
    • Transcriptional activation of the glucose-regulated protein genes and their heterologous fusion genes by beta-mercaptoethanol
    • Kim YK, Lee AS. 1987. Transcriptional activation of the glucose-regulated protein genes and their heterologous fusion genes by beta-mercaptoethanol. Mol Cell Biol 7:2974-2976.
    • (1987) Mol Cell Biol , vol.7 , pp. 2974-2976
    • Kim, Y.K.1    Lee, A.S.2
  • 29
    • 0023546204 scopus 로고
    • Regulation of the glucose-regulated protein genes by beta-mercaptoethanol requires de novo protein synthesis and correlates with inhibition of protein glycosylation
    • Kim YK, Kim KS, Lee AS. 1987. Regulation of the glucose-regulated protein genes by beta-mercaptoethanol requires de novo protein synthesis and correlates with inhibition of protein glycosylation. J Cell Physiol 133:553-559.
    • (1987) J Cell Physiol , vol.133 , pp. 553-559
    • Kim, Y.K.1    Kim, K.S.2    Lee, A.S.3
  • 32
    • 0014949207 scopus 로고
    • Cleavage of structural proteins during the assembly of the head of bacteriophage T4
    • Laemmli UK. 1970. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227:680-685.
    • (1970) Nature , vol.227 , pp. 680-685
    • Laemmli, U.K.1
  • 33
    • 0026843954 scopus 로고
    • Mammalian stress response: Induction of the glucose-regulated protein family
    • Lee AS. 1992. Mammalian stress response: induction of the glucose-regulated protein family. Curr Opin Cell Biol 4:267-273.
    • (1992) Curr Opin Cell Biol , vol.4 , pp. 267-273
    • Lee, A.S.1
  • 36
    • 0031015982 scopus 로고    scopus 로고
    • Suppression of grp78 core promoter element-mediated stress induction by the dbpA and dbpB (YB-1) cold shock domain proteins
    • Li WW, Hsiung Y, Wong V, Galvun K, Zhou Y, Lee AS. 1997a, Suppression of grp78 core promoter element-mediated stress induction by the dbpA and dbpB (YB-1) cold shock domain proteins. Mol Cell Biol 17:61-68.
    • (1997) Mol Cell Biol , vol.17 , pp. 61-68
    • Li, W.W.1    Hsiung, Y.2    Wong, V.3    Galvun, K.4    Zhou, Y.5    Lee, A.S.6
  • 37
    • 0031014395 scopus 로고    scopus 로고
    • 2+ depletion and formation of aberrant proteins: Activation of the conserved stress-inducible grp core promoter element by the human nuclear factor YY1
    • 2+ depletion and formation of aberrant proteins: activation of the conserved stress-inducible grp core promoter element by the human nuclear factor YY1. Mol Cell Biol 17:54-60.
    • (1997) Mol Cell Biol , vol.17 , pp. 54-60
    • Li, W.W.1    Hsiung, Y.2    Zhou, Y.3    Roy, B.4    Lee, A.S.5
  • 38
    • 0030830633 scopus 로고    scopus 로고
    • Association of glucose-regulated protein (grp78) with human keratin 8
    • Liao J, Price D, Omary MB. 1997. Association of glucose-regulated protein (grp78) with human keratin 8. FEBS Lett 417:316-320.
    • (1997) FEBS Lett , vol.417 , pp. 316-320
    • Liao, J.1    Price, D.2    Omary, M.B.3
  • 39
    • 0027958873 scopus 로고
    • The glucose-regulated proteins (GRP78 and GRP94): Functions, gene regulation, and applications
    • Little E, Ramakrishnan M, Roy B, Gazit G, Lee AS. 1994. The glucose-regulated proteins (GRP78 and GRP94): functions, gene regulation, and applications. Crit Rev Eukaryot Gene Expr 4:1-18
    • (1994) Crit Rev Eukaryot Gene Expr , vol.4 , pp. 1-18
    • Little, E.1    Ramakrishnan, M.2    Roy, B.3    Gazit, G.4    Lee, A.S.5
  • 40
    • 0026662420 scopus 로고
    • Brefeldin A as regulator of grp 78 gene expression in mammalian cells
    • Liu ES, Ou JH, Lee AS. 1992. Brefeldin A as regulator of grp 78 gene expression in mammalian cells. J Biol Chem 267:7128-7133.
    • (1992) J Biol Chem , vol.267 , pp. 7128-7133
    • Liu, E.S.1    Ou, J.H.2    Lee, A.S.3
  • 42
    • 0028152333 scopus 로고
    • MAP kinase kinase kinase, MAP kinase kinase and MAP kinase
    • Marshall CJ. 1994. MAP kinase kinase kinase, MAP kinase kinase and MAP kinase. Curr Opin Genet Dev 4:82-89.
    • (1994) Curr Opin Genet Dev , vol.4 , pp. 82-89
    • Marshall, C.J.1
  • 43
    • 0020478786 scopus 로고
    • 2+-mediated activation of phosphoenolpyruvate carboxykinase occurs via release of FeII from rat liver mitochondria
    • 2+-mediated activation of phosphoenolpyruvate carboxykinase occurs via release of FeII from rat liver mitochondria. J Biol Chem 257:3628-3635.
    • (1982) J Biol Chem , vol.257 , pp. 3628-3635
    • Merryfield, M.L.1    Lardy, H.A.2
  • 44
    • 0031009434 scopus 로고    scopus 로고
    • Cdc42Hs, but not Rac1, inhibits serum-stimulated cell cycle progression at G1/S through a mechanism requiring p38/RK
    • Molnar A, Theodoras AM, Zon LI, Kyriakis JM. 1997. Cdc42Hs, but not Rac1, inhibits serum-stimulated cell cycle progression at G1/S through a mechanism requiring p38/RK. J Biol Chem 272:13229-13235.
    • (1997) J Biol Chem , vol.272 , pp. 13229-13235
    • Molnar, A.1    Theodoras, A.M.2    Zon, L.I.3    Kyriakis, J.M.4
  • 46
    • 0031054643 scopus 로고    scopus 로고
    • Immunoglobulin binding protein (BiP) function is required to protect cells from endoplasmic reticulum stress but is not required for the secretion of selective proteins
    • Morris JA, Dorner AJ, Edwards CA, Hendershot LM, Kaufman RJ. 1997. Immunoglobulin binding protein (BiP) function is required to protect cells from endoplasmic reticulum stress but is not required for the secretion of selective proteins. J Biol Chem 272:4327-4334.
    • (1997) J Biol Chem , vol.272 , pp. 4327-4334
    • Morris, J.A.1    Dorner, A.J.2    Edwards, C.A.3    Hendershot, L.M.4    Kaufman, R.J.5
  • 47
    • 0026672998 scopus 로고
    • MAP kinases: Charting the regulatory pathways
    • Pelech SL, Sanghera JS. 1992. MAP kinases: charting the regulatory pathways. Science 257:1355-1356.
    • (1992) Science , vol.257 , pp. 1355-1356
    • Pelech, S.L.1    Sanghera, J.S.2
  • 48
    • 0026611735 scopus 로고
    • Brefeldin A, thapsigargin, and AIF4-stimulate the accumulation of GRP78 mRNA in a cycloheximide dependent manner, whilst induction by hypoxia is independent of protein synthesis
    • Price BD, Mannheim-Rodman LA, Calderwood SK. 1992. Brefeldin A, thapsigargin, and AIF4-stimulate the accumulation of GRP78 mRNA in a cycloheximide dependent manner, whilst induction by hypoxia is independent of protein synthesis. J Cell Physiol 152:545-552.
    • (1992) J Cell Physiol , vol.152 , pp. 545-552
    • Price, B.D.1    Mannheim-Rodman, L.A.2    Calderwood, S.K.3
  • 49
    • 0028935270 scopus 로고
    • Pro-inflammatory cytokines and environmental stress cause p38 mitogen-activated protein kinase activation by dual phosphorylation on tyrosine and threonine
    • Raingeaud J, Gupta S, Rogers JS, Dickens M, Han J, Ulevitch RJ, Davis RJ. 1995. Pro-inflammatory cytokines and environmental stress cause p38 mitogen-activated protein kinase activation by dual phosphorylation on tyrosine and threonine. J Biol Chem 270:7420-7426.
    • (1995) J Biol Chem , vol.270 , pp. 7420-7426
    • Raingeaud, J.1    Gupta, S.2    Rogers, J.S.3    Dickens, M.4    Han, J.5    Ulevitch, R.J.6    Davis, R.J.7
  • 50
    • 0021945545 scopus 로고
    • Calcium ionophore A23187 induces expression of glucose-regulated genes and their heterologous fusion genes
    • Resendez E Jr, Attenello JW, Grafsky A, Chang CS, Lee AS. 1985. Calcium ionophore A23187 induces expression of glucose-regulated genes and their heterologous fusion genes. Mol Cell Biol 5:1212-1219.
    • (1985) Mol Cell Biol , vol.5 , pp. 1212-1219
    • Resendez E., Jr.1    Attenello, J.W.2    Grafsky, A.3    Chang, C.S.4    Lee, A.S.5
  • 51
    • 0023715948 scopus 로고
    • Identification of highly conserved regulatory domains and protein-binding sites in the promoter of the rat and human genes encoding the stress-inducible 78-kilodalton glucose-regulated protein
    • Resendez E Jr, Wooden SK, Lee AS. 1988. Identification of highly conserved regulatory domains and protein-binding sites in the promoter of the rat and human genes encoding the stress-inducible 78-kilodalton glucose-regulated protein. Mol Cell Biol 8:4579-4584.
    • (1988) Mol Cell Biol , vol.8 , pp. 4579-4584
    • Resendez E., Jr.1    Wooden, S.K.2    Lee, A.S.3
  • 52
    • 0019316108 scopus 로고
    • Effect of ruthenium red on calcium efflux from rat liver mitochondria
    • Rigoni F, Mathien-Shire Y, Deana R. 1980. Effect of ruthenium red on calcium efflux from rat liver mitochondria. FEBS Lett 120:255-258.
    • (1980) FEBS Lett , vol.120 , pp. 255-258
    • Rigoni, F.1    Mathien-Shire, Y.2    Deana, R.3
  • 53
    • 0028022750 scopus 로고
    • A novel kinase cascade triggered by stress and heat shock that stimulates MAPKAP kinase-2 and phosphorylation of the small heat shock proteins
    • Rouse J, Cohen P, Trigon S, Morange M, Alonso-Llamazares A, Zamanillo D, Hunt T, Nebreda AR. 1994. A novel kinase cascade triggered by stress and heat shock that stimulates MAPKAP kinase-2 and phosphorylation of the small heat shock proteins. Cell 78:1027-1037.
    • (1994) Cell , vol.78 , pp. 1027-1037
    • Rouse, J.1    Cohen, P.2    Trigon, S.3    Morange, M.4    Alonso-Llamazares, A.5    Zamanillo, D.6    Hunt, T.7    Nebreda, A.R.8
  • 54
    • 0028967755 scopus 로고
    • Transduction of calcium stress through interaction of the human transcription factor CBF with the proximal CCAAT regulatory element of the grp78/ BiP promoter
    • Roy B, Lee AS. 1995. Transduction of calcium stress through interaction of the human transcription factor CBF with the proximal CCAAT regulatory element of the grp78/ BiP promoter. Mol Cell Biol 15:2263-2274.
    • (1995) Mol Cell Biol , vol.15 , pp. 2263-2274
    • Roy, B.1    Lee, A.S.2
  • 55
    • 0029803009 scopus 로고    scopus 로고
    • Calcium-sensitive transcriptional activation of the proximal CCAAT regulatory element of the grp78/BiP promoter by the human nuclear factor CBF/NF-Y
    • Roy B, Li WW, Lee AS. 1996. Calcium-sensitive transcriptional activation of the proximal CCAAT regulatory element of the grp78/BiP promoter by the human nuclear factor CBF/NF-Y. J Biol Chem 272:28995-29002.
    • (1996) J Biol Chem , vol.272 , pp. 28995-29002
    • Roy, B.1    Li, W.W.2    Lee, A.S.3
  • 56
    • 0030753164 scopus 로고    scopus 로고
    • Effect of cysteine, N-acetyl-L-cysteine and glutathione on cytotoxic activity of antioxidants
    • Satoh K, Sakagami H. 1997. Effect of cysteine, N-acetyl-L-cysteine and glutathione on cytotoxic activity of antioxidants. Anticancer Res 17:2175-2179.
    • (1997) Anticancer Res , vol.17 , pp. 2175-2179
    • Satoh, K.1    Sakagami, H.2
  • 57
    • 0030772692 scopus 로고    scopus 로고
    • Gene expression in liver after toxic injury: Analysis of heat shock response and oxidative stress-inducible genes
    • Schiaffonati L, Tiberio L. 1997. Gene expression in liver after toxic injury: analysis of heat shock response and oxidative stress-inducible genes. Liver 17:183-191.
    • (1997) Liver , vol.17 , pp. 183-191
    • Schiaffonati, L.1    Tiberio, L.2
  • 58
    • 0028805786 scopus 로고
    • Induction of oxidative stress by okadaic acid is required for activation of transcription factor NF-kappa B
    • Schmidt KN, Traenckner EB, Meier B, Baeuerle PA. 1995. Induction of oxidative stress by okadaic acid is required for activation of transcription factor NF-kappa B. J Biol Chem 270:27136-27142.
    • (1995) J Biol Chem , vol.270 , pp. 27136-27142
    • Schmidt, K.N.1    Traenckner, E.B.2    Meier, B.3    Baeuerle, P.A.4
  • 59
    • 0027974133 scopus 로고
    • Assessing oxygen radicals as mediators in activation of inducible eukaryotic transcription factor NF-kappa B
    • Schreck R, Baeuerle PA. 1994. Assessing oxygen radicals as mediators in activation of inducible eukaryotic transcription factor NF-kappa B. Methods Enzymol 234:151-163.
    • (1994) Methods Enzymol , vol.234 , pp. 151-163
    • Schreck, R.1    Baeuerle, P.A.2
  • 60
    • 0010625474 scopus 로고
    • Glucose depletion accounts for the induction of two transformation-sensitive membrane proteins in Rous sarcoma virus-transformed chick embryo fibroblasts
    • Shiu RPC, Pouyssegur J, Pastan I. 1977. Glucose depletion accounts for the induction of two transformation-sensitive membrane proteins in Rous sarcoma virus-transformed chick embryo fibroblasts. Proc Natl Acad Sci USA 74:3840-3844.
    • (1977) Proc Natl Acad Sci USA , vol.74 , pp. 3840-3844
    • Shiu, R.P.C.1    Pouyssegur, J.2    Pastan, I.3
  • 62
    • 0028950664 scopus 로고
    • Inhibition of specific binding of okadaic acid to protein phosphatase 2A by microcystin-LR, calyculin-A and tautomycin: Method of analysis of interactions of tight-binding ligands with target protein
    • Takai A, Sasaki K, Nagai H, Mieskes G, Isobe M, Isono K, Yasumoto T. 1995. Inhibition of specific binding of okadaic acid to protein phosphatase 2A by microcystin-LR, calyculin-A and tautomycin: method of analysis of interactions of tight-binding ligands with target protein. Biochem J 306:657-665.
    • (1995) Biochem J , vol.306 , pp. 657-665
    • Takai, A.1    Sasaki, K.2    Nagai, H.3    Mieskes, G.4    Isobe, M.5    Isono, K.6    Yasumoto, T.7
  • 63
    • 0030847655 scopus 로고    scopus 로고
    • Preparation, characterization and utility of a novel antibody for resolving the spatial and temporal dynamics of the calcium chelator BAPTA
    • Tymianski M, Sattler R, Bernstein G, Jones OT. 1997. Preparation, characterization and utility of a novel antibody for resolving the spatial and temporal dynamics of the calcium chelator BAPTA. Cell Calcium 22: 111-120.
    • (1997) Cell Calcium , vol.22 , pp. 111-120
    • Tymianski, M.1    Sattler, R.2    Bernstein, G.3    Jones, O.T.4
  • 66
    • 0029938805 scopus 로고    scopus 로고
    • Stress-induced phosphorylation and activation of the transcription factor CHOP (GADD153) by p38 MAP kinase
    • Wang XZ, Ron D. 1996. Stress-induced phosphorylation and activation of the transcription factor CHOP (GADD153) by p38 MAP kinase. Science 272:1347-1349.
    • (1996) Science , vol.272 , pp. 1347-1349
    • Wang, X.Z.1    Ron, D.2
  • 67
    • 0000166773 scopus 로고    scopus 로고
    • Complex regulation of heat shock- and glucose-responsive genes in human cells
    • Watowich SS, Morimoto RI. 1998. Complex regulation of heat shock- and glucose-responsive genes in human cells. Mol Cell Biol 8:393-405.
    • (1998) Mol Cell Biol , vol.8 , pp. 393-405
    • Watowich, S.S.1    Morimoto, R.I.2
  • 69
    • 0029129557 scopus 로고
    • Serine/threonine protein phosphatases
    • Wera S, Hemmings BA. 1995. Serine/threonine protein phosphatases. Biochem J 311:17-29.
    • (1995) Biochem J , vol.311 , pp. 17-29
    • Wera, S.1    Hemmings, B.A.2
  • 70
    • 0030911732 scopus 로고    scopus 로고
    • Activation of transcription factor NF-kappaB and p38 mitogen-activated protein kinase is mediated by distinct and separate stress effector pathways
    • Wesselborg S, Bauer MKA, Vogt M, Schmitz ML, Schulze-Osthoff K. 1997. Activation of transcription factor NF-kappaB and p38 mitogen-activated protein kinase is mediated by distinct and separate stress effector pathways. J Biol Chem 272:12422-12429.
    • (1997) J Biol Chem , vol.272 , pp. 12422-12429
    • Wesselborg, S.1    Bauer, M.K.A.2    Vogt, M.3    Schmitz, M.L.4    Schulze-Osthoff, K.5


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