Effect of cysteine, N-acetyl-L-cysteine and glutathione on cytotoxic activity of antioxidants

Anticancer Research

Volumn 17, Issue 3 C, 1997, Pages 2175-2179

  Satoh, Kazue ^a   Sakagami, Hiroshi ^a  

^a SHOWA UNIVERSITY   (Japan)

Author keywords

Antioxidant; Ascorbate; Cysteine; Cytotoxicity; ESR; Interaction; Radical

Indexed keywords

ACETYLCYSTEINE; AMINO ACID; ANTIOXIDANT; ASCORBIC ACID; BENZYLIDENE DERIVATIVE; CAFFEIC ACID; CYSTEINE; GALLIC ACID; GLUTATHIONE; METHIONINE; METHIONINE SULFOXIDE;

ARTICLE; CONTROLLED STUDY; DRUG CYTOTOXICITY; ELECTRON SPIN RESONANCE; HUMAN; HUMAN CELL; PRIORITY JOURNAL;

ACETYLCYSTEINE; AMINO ACIDS; AMINO ACIDS, ESSENTIAL; ANTINEOPLASTIC AGENTS; ANTIOXIDANTS; ASCORBIC ACID; BENZYLIDENE COMPOUNDS; CAFFEIC ACIDS; CELL SURVIVAL; CYSTEINE; ELECTRON SPIN RESONANCE SPECTROSCOPY; FREE RADICALS; GALLIC ACID; GLUTATHIONE; HL-60 CELLS; HUMANS; KINETICS;

EID: 0030753164     PISSN: 02507005     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (12)

1. Sakagami H, Kuribayashi N, Iida M, Hagiwara T, Takahashi H, Yoshidu H, Shiota F, Ohata H, Momose K and Takeda M: The requirement for and mobilization of calcium during induction by sodium ascorbate and by hydrogen peroxide of cell death. Life Sciences 58: 1131-1138, 1996.
2. Sakagami H, Satoh K, Ohata N, Takahashi H, Yoshida H, Iida M, Kuribayashi N, Sakagami T, Momose K and Takeda M: Relationship between ascorbyl radical intensity and apoptosis-inducing activity. Anticancer Res 16: 2635-2644, 1996.
3. Sakagami H, Kuribayashi N, Iida M, Sakagami T, Takeda M, Fukuchi K, Gomi K, Ohata H, Momose K, Kawazoe Y, Hatano T, Yoshida T and Okuda T: Induction of DNA fragmentation by tannin- and lignin-related substances. Anticancer Res 15: 2121-2128, 1995.
4. Sakagami H and Satoh K: Prooxidant action of two antioxidants: ascorbic acid and gallic acid. Anticancer Res 17: in press, 1997.
5. Sakagami H, Satoh K, Hatano T, Yoshida T and Okuda T: Possible role of radical intensity and oxidation potential for gallic acid-induced apoptosis. Anticancer Res 17: in press, 1997.
6. Sakagami H, Satoh K, Fukuchi K, Gomi K and Takeda M: Effect of an iron-chelator on ascorbate-induced cytotoxicity. Free Radic Biol Med, in press, 1997.
7. Sakagami H, Satoh K, Kadofuku T and Takeda M. Methionine oxidation and apoptosis induction by ascorbate, gallate and hydrogen peroxide. Anticancer Res 17: in press, 1997.
8. Sakagami H, Satoh K, Makino Y, Kojima T and Takeda M: Effect of α-tocopherol on cytotoxicity induced by UV irradiation and antioxidants. Anticancer Res 17: 2079-2082, 1997.
9. Sakagami H and Satoh K: The interaction between two antioxidants, sodium ascorbate and gallic acid: radical intensity and apoptosis induction. Anticancer Res 16: 1231-1234, 1996.
10. Satoh K and Sakagami H: Effect of copper and iron ions on cytotoxicity induced by ascorbate, gallate and caffeate. Anticancer Res 17: 2181-2184, 1997.
11. Fujinaga S, Sakagami H, Kuribayashi N, Takahashi H, Amano Y, Sakagami T and Takeda M: Possible role of hydrogen peroxide in apoptosis induction by ascorbic acid in human myelogenous leukemic cell lines. Showa Univ J Med Sci 6: 135-144, 1994.
12. Sakagami H, Asano K, Fukuchi K, Gomi K, Ota H, Kazama K, Tanuma S and Kochi M: Induction of tumor degeneration by sodium benzylideneascorbate. Anticancer Res 11: 1533-1538, 1991.