Modulation of protein phosphorylation and stress protein expression by okadaic acid on heat shock cells

Journal of Cellular Biochemistry

Volumn 61, Issue 2, 1996, Pages 255-265

  Chen, Kuang Den ^a   Chu, Jao Jia ^a   Lai, Yiu Kay ^a  

^a NATIONAL TSING HUA UNIVERSITY   (Taiwan)

Author keywords

glucose regulated proteins; heat shock; heat shock proteins; okadaic acid; protein phosphorylation; vimentin

Indexed keywords

HEAT SHOCK PROTEIN; OKADAIC ACID;

ANIMAL CELL; ARTICLE; CELL SURVIVAL; HEAT SHOCK; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN INDUCTION; PROTEIN PHOSPHORYLATION; RAT;

ANIMALS; CELL SURVIVAL; ENZYME INHIBITORS; GENE EXPRESSION REGULATION; HEAT-SHOCK PROTEINS; HEAT-SHOCK RESPONSE; OKADAIC ACID; PHOSPHOPROTEIN PHOSPHATASE; PHOSPHORYLATION; RATS; TUMOR CELLS, CULTURED;

EID: 0029871793     PISSN: 07302312     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-4644(19960501)61:2<255::AID-JCB9>3.0.CO;2-T     Document Type: Article

References (38)

1. Alexandre S, Nakaki T, Vanhamme L, Lee AS (1991): A binding site for the cyclic adenosine 3′,5′-monophosphate-responsive element-binding protein as a regulatory element in the grp78 promoter. Mol Endocrinol 5:1862-1872.
2. Baler R, Dahl G, Voellmy R (1993): Activation of human heat shock genes is accompanied by oligomerization, modification, and rapid translocation of heat shock transcription factor HSF1. Mol Cell Biol 13:2486-2496.
3. Becker J, Craig EA (1994): Heat-shock proteins as molecular chaperones. Eur J Biochem 219:11-23.
4. Chang NT, Huang LE, Lui AYC (1993): Okadaic acid markedly potentiates the heat-induced HSP-70 promoter activity. J Biol Chem 268:1436-1439.
5. Chao CC-K, Yam W-C, Sun N-K (1993): A direct-repeat sequence is required for up-regulation of the human BIP gene by brefeldin-A, tunicamycin, and calcium ionophore A23187. J Cell Biochem S17A:104.
6. Cheng T-J, Lai Y-K (1994): Transient increase in vimentin phosphorylation and vimentin-HSC70 association in 9L rat brain tumor cells experiencing heat-shock. J Cell Biochem 54:100-109.
7. Cohen P, Holmes CF, Tsukitani Y (1990): Okadaic acid: A new probe for the study of cellular regulation. Trends Biochem Sci 15:98-102.
8. DeJong WW, Bloemendal H, Hoekman WA, Mulder JWM (1986): Heat-shock response of the rat lens. J Cell Biol 102:104-111.
9. Duncan RF, Hershey JWB (1984): Heat shock-induced translational alterations in HeLa cells: Initiation factor modifications and the inhibition of translation. J Biol Chem 259:11882-11889.
10. Duncan RF, Hershey JW (1989): Protein synthesis and protein phosphorylation during heat stress, recovery, and adaptation. J Cell Biol 109:1467-1481.
11. Gonzalez GA, Yamamoto KK, Fischer WH, Karr D, Menzel P, Biggs W, Vale WW, Montminy MR (1989): A cluster of phosphorylation sites on the cyclic AMP-regulated nuclear factor CREB predicted by its sequence. Nature 337:749-752
12. Hightower LE, White FP (1981): Cellular-responses to stress - Comparison of a family of 71-kilodalton proteins rapidly synthesized in rat-tissue slices and canavanine-treated cells in culture. J Cell Physiol 108:261-275.
13. Hou M-C, Shen C-H, Lee W-C, Lai Y-K (1993): Okadaic acid as an inducer of the 78-kDa glucose-regulated protein in 9L rat brain tumor cells. J Cell Biochem 51:91-101.
14. Kozutsumi Y, Segal M, Normington K, Gething MJ, Sambrook J (1988): The presence of malfolded proteins in the endoplasmic reticulum signals the induction of glucose-regulated proteins. Nature 332:462-464.
15. Laemmli UK (1970): Cleavage of structural proteins during the assembly of head of bacteriophage. Nature 227:680-685.
16. Lai Y-K, Shen C-H, Cheng T-J, Hou M-C, Lee W-C (1993a): Enhanced phosphorylation of a 65 kDa protein is associated with rapid induction of stress proteins in 9L rat brain tumor cells. J Cell Biochem 51:369-379.
17. Lai Y-K, Lee W-C, Chen K-D (1993b): Vimentin serves as a phosphate sink during the apparent activation of protein kinases by okadaic acid in mammalian cells. J Cell Biochem 53:161-168.
18. Lee W-C, Lin K-Y, Chen C-M, Chen Z-T, Liu H-J, Lai Y-K (1991): Induction of heat-shock response and alterations of protein phosphorylation by a novel topoisomerase II inhibitor, Withangulatin A, in 9L rat brain tumor cells. J Cell Physiol 149:66-76.
19. Lee W-C, Yu J-S, Yang S-D, Lai Y-K (1992a): Reversible hyperphosphorylation and reorganization of vimentin intermediate filaments by okadaic acid in 9L rat brain tumor cells. J Cell Biochem 49:378-393.
20. Lee W-C, Lin K-Y, Chen K-D, Lai Y-K (1992b): Induction of HSP70 is associated with vincristine resistance in heat-shock 9L rat brain tumor cells. Br J Cancer 66:653-659.
21. 2+-ATPase inhibitor thapsigargin. J Biol Chem 268:12003-12009.
22. Li WW, Sistonen L, Morimoto RI, Lee AS (1994): Stress induction of the mammalian GRP78/BiP protein gene: In vivo genomic footprinting and identification of p70CORE from human nuclear extract as a DNA-binding component specific to the stress regulatory element. Mol Cell Biol 14:5533-5546.
23. Lindquist S, Craig EA (1988): The heat-shock proteins. Annu Rev Biochem 22:631-677.
24. Liu ES, Ou J, Lee AS (1992): Brefeldin-A as a regulator of grp78 gene-expression in mammalian cells. J Biol Chem 267:7128-7133.
25. Maher PA, Pasquale EB (1989): Heat shock induces protein tyrosine phosphorylation in cultured cells. J Cell Biol 108:2029-2036.
26. Mivechi NF, Murai T, Hahn GM (1994): Inhibitors of tyrosine and ser/thr phosphatases modulate the heat-shock response. J Cell Biochem 54:186-197.
27. Morimoto R (1993): Cells in stress: Transcriptional activation of heat-shock genes. Science 259:1409-1410.
28. Munro S, Pelham HRB (1986): A hsp70-like protein in the ER: Identity with the 78 kd glucose-regulated protein and immunoglobulin heavy chain binding protein. Cell 57:1223-1236.
29. Pelham HRB (1986): Speculations on the functions of the major heat shock and glucose-regulated proteins. Cell 46:959-961.
30. Price BD, Mannheim-Rodman LA, Calderwood SK (1992): Brefeldin-A, thapsigagin, and aif-4 stimulate the accumulation of grp78 messenger-RNA in a cycloheximide dependent manner, while induction by hypoxia is independent of protein synthesis. J Cell Physiol 152:545-552.
31. Sarge KD, Murphy SP, Morimoto RI (1993): Activation of heat shock gene transcription by HSF1 involves oligomerization, acquisition of DNA binding activity, and nuclear localization and can occur in the absence of stress. Mol Cell Biol 13:1392-1407.
32. Schlesinger MJ (1990): Heat shock proteins. J Biol Chem 265:12111-12114.
33. Watowich SS, Morimoto RI (1988): Complex regulation of heat shock-responsive and glucose-responsive genes in human-cells. Mol Cell Biol 8:393-405.
34. Weizsaecker M, Deen DF, Rosenblum ML, Hoshino T, Gutin PH, Baker M (1981): The 9L rat brain tumor: Description and application of animal model. J Neurol 224:183-192.
35. Welch WJ (1992): Mammalian stress response: Cell physiology, structure/function of stress proteins, and implications for medicine and disease. Physiol Rev 72:1063-1081.
36. Winning RS, Bols CN, Heikkila JJ (1991): Tunicamycin-inducible polypeptide synthesis during Xenopus laevis. Differentiation 46:167-172.
37. Wooden SK, Li L-J, Navarro D, Qadri I, Pereira L, Lee AS (1991): Transactivation of the grp78 promoter by malfolded proteins, glycosylation containing a CCAAT motif which interacts with CTF/NF-I. Mol Cell Biol 11:5612-5623.
38. Yatsunami J, Fujiki H, Suganuma M, Yoshizawa S, Eriksson JE, Olson MOJ, Goldman RD (1991): Vimentin is hyperphosphorylated in primary human fibroblasts treated with okadaic acid. Biochem Biophys Res Commun 177: 1165-1170.