A yeast heterogeneous nuclear ribonucleoprotein complex associated with RNA polymerase II

Genetics

Volumn 154, Issue 2, 2000, Pages 557-571

  Conrad, Nicholas K ^a,b,c,d   Wilson, Scott M ^a,b,c,d   Steinmetz, Eric J ^a,b,c,d   Patturajan, Meera ^a,b,c,d   Brow, David A ^a,b,c,d   Swanson, Maurice S ^a,b,c,d   Corden, Jeffry L ^a,b,c,d  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF FLORIDA COLLEGE OF MEDICINE   (United States)

^c UNIVERSITY OF WISCONSIN SCHOOL OF MEDICINE AND PUBLIC HEALTH   (United States)

^d NATIONAL CANCER INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

RIBONUCLEOPROTEIN; RNA BINDING PROTEIN; RNA POLYMERASE II;

ALLELE; ARTICLE; CARBOXY TERMINAL SEQUENCE; GENE CONTROL; GENE DELETION; GENETIC HETEROGENEITY; NONHUMAN; PRIORITY JOURNAL; RNA BINDING; RNA PROCESSING; SEQUENCE HOMOLOGY; TRANSCRIPTION REGULATION; YEAST;

ALLELES; BASE SEQUENCE; DNA PRIMERS; FUNGAL PROTEINS; GENES, SUPPRESSOR; HETEROGENEOUS-NUCLEAR RIBONUCLEOPROTEINS; PHOSPHORYLATION; PRECIPITIN TESTS; PROTEIN BINDING; RIBONUCLEOPROTEINS; RNA POLYMERASE II; RNA PRECURSORS; RNA PROCESSING, POST-TRANSCRIPTIONAL; RNA, MESSENGER; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS; TEMPERATURE; TRANSCRIPTION, GENETIC;

MAMMALIA;

EID: 0033975560     PISSN: 00166731     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (64)

1. AUSUBEL, F. M., R. BRENT, R. E. KINGSTON, D. D. MOOKE,J. G. SEIDMAN et al. (Editors), 1995 Current Protocol's in Molecular Biology. John Wiley Sons, New York.
2. BENDER, A., and J. R. PRINGLE, 1991 Use of a screen for synthetic lelhal and multicopy suppressee mutants to identify two new genes involved in morphogenesis in Saeeharomyces cerevisiae. Mol. Cell. Biol. 11: 1295-1305.
3. BOEKE.J. D., F. I.ACROUTE and G. R. FINK, 1984 A positive selection for mutants lacking oroticline-5'-phosphate decarboxylase activity in yeast: 5-fluoro-orotic acid resistance. Mol. Gen. Genet. 197: 345-346.
4. BRACIIMANN, C. B., A. DAVIES, G. J. COST, E. CAPUTO.J. I.i et al. 1998 Designer deletion strains derived from Saccharomyces cerevisiae S288C: a useful set of strains and plasmids for PCR-mediated gene disruption and other applications. Yeast 14: 115-132.
5. CACERES, J. F., G. R. SCREATON and A. R. KRAINER, 1998 A specific subset of SR proteins shuttles continuously between the nucleus and the cytoplasm. Genes Dev. 12: 55-66.
6. CHO, E. J., T. TAKAGI, C. R. MOORE and S. BURATOWSKI, 1997 mRN'A capping enzyme is recruited to the transcription complex by phosphorylalion of the RNA polymcrase II carboxy-terminal domain. Genes Dcv. 11: 3319-3326.
7. CHO, E. J., C. R. RODRIQUEZ, T. TAKAGI and S. BURATOWSKI, 1998 Allosteric interactions between capping enzyme subunits and the RNA polymcrase II carboxy-terminal domain. Genes Dcv. 12: 3482-3487.
8. ClIRISTIANSON, T. W., R. S. SlKORSKI, M. DANTE, J. H. SlIERO and P. HiETER, 1992 Multifunctional yeast high-copy-ntmiber shuttle vectors. Gene 110: 119-122.
9. CONNELLY, C., and P. MIETER, 1996 Budding yeast SKI'1 encodes an evolutionarily conserved kinctochore protein required for cell cycle progression. Cell 86: 275-285.
10. CORDEN, J. L., and M. PATTURAJAN, 1997 A CTD function linking transcription to splicing. Trends Biochcm. Sei. 22: 413-416.
11. DAIIMUS, M. E., 1996 Reversible phospliorylation of the C-terminal domain of RNA polymerase II. J. Biol. Chem. 271: 19009-19012.
12. Fu, X. D., 1995 The superfamily of arginine/serinc-rich splicing factors. RNA 1: 663-680.
13. GüLDENER, U., S. HECK, T. FIELDER, J. BEINHAUER and J. H. HEGEMANN, 1996 A new efficient gene dismption cassette for repeated use in budding yeast. Nucleic Acids Res. 24: 2519-2524.
14. HARLOW, E., and D. LANE (Editors), 1988 Antibodies: A laboratory Manual. Cold Spring Harbor I-aboratory, Cold Spring Harbor, NY.
15. HARTZOG, G. A., T. WADA, H. HANDA and F. WINSTON, 1998 Evidence that Spt4, Spt5, and Spt6 control transcription elongation by RNA polymerase II in Saccharomyces cerevisiae. Genes Dev. 12: 357-369.
16. HENRY, M., C. Z. BORLAND, M. BOSSIE and P. A. SILVER, 199G Potential RNA binding proteins in Saccharomyces cerevlsiae identified as suppressors of temperature-sensitive mutations in NPI3. Genetics 142: 103-115.
17. HIROSE, Y., andj. L. MANLEY, 1998 RNA polymerase II is an essential mRNA polyadenylation factor. Nature 395: 93-96.
18. HIROSE, Y., R. TACKE and J. L. MANLEY, 1999 Phosphor) lated RNA polymerase II stimulates pre-mRNA splicing. Genes Dev. 13: 1234-1239.
19. Ho, C. K., and S. SIIUMAN, 1999 Distinct roles for CTD ser-2 and ser-5 phospliorylation in the recruitment and allostcric activation of mammalian mRNA capping enzyme. Mol. Cell 3: 405-411.
20. Ho, C. K., V. SRISKANDA, S. MCCRACKEN, D. BENTLEY, B. SCHWER et al. 1998 The guanylyltransferase domain of mammalian mRNA capping enzyme binds to the phosphorylaled carboxyl-terminal domain of RNA polymerase II. J. Biol. Chem. 273: 9577-9585.
21. JAMES, P.,J. HALLADAY and E. A. CRAIG, 1996 Genomic libraries and a host strain designed for highly efficient two-hybrid selection in yeast. Genetics 144: 1425-1436.
22. KESSLER, M. M., M. F. HENRY, E. SIIEN, J. ZIIAO, S. GROSS et al. 1997 Hrpl, a sequence-specific RNA-binding protein that shuttles between the nucleus and the cytoplasm, is required for mRNA 3'-cnd formation in yeast. Genes Dev. 11: 2545-2556.
23. KIM, E., . Du, D. B. BREGMAN and S. L. WARREN, 1997 Splicing factors associate with h)perphosphorylated RNA polymerasc II in the absence of pre-mRNA. J. Cell Biol. 136: 19-28.
24. KRECIC, A. M., and M. S. SWANSON, 1999 hnRNP complexes: composition, structure, and function. Curr. Opin. Cell Biol. 11:363-371.
25. LEE, J. M., and A. L. GREENLEAF, 1989 A protein kinase that phosphorylales the C-tcrminal repeat domain of the largest subunit of RNA polymerase II. Proc. Natl. Acad. Sei. USA 86: 3624-3628.
26. LEE, J. M., and A. L. GREENLEAF, 1991 CTD kinase large subunit is encoded by CTK1, a gene required for normal growth of Saccharomyces cerevisiae. Gene Expr. 1: 149-167.
27. I.EE.J. M., and A. L. GRKENLEAF, 1997 Modulation of RNA polymer-asc II elongation efficiency by C-terminal hcptapcptide repeat domain kinase I.J. Biol. Chcm. 272: 10990-10993.
28. I.EE, M. S., M. HENRY and P. A. SILVER, 1996 A protein that shuttles between the nucleus and the cytoplasm is an important mediator of RNA export. Genes Dev. 10: 1233-1246.
29. MCCRACKEN, S., N. FONG, E. ROSONIA, K. YANKULOV, G. BROTHERS el at. 1997a 5' capping enzymes arc targeted to prc-mRNA by binding to the phosphorylated C-terminal domain of RNA polymerase II. Genes Dev. II: 3306-3318.
30. MCCRACKEN, S., N. FONT, K. YANKULOV, S. BALLANTYNE, G. PAN el al. 1997b The C-tcrminal domain of RNA polymerase II couples mRNA processing to transcription. Nature 385: 357-361.
31. MEISELS, E., O. GILEADI andj. I- CORDEN, 1995 Partial truncation of the yeast RNA polymerase II carboxyl-terminal domain preferentially reduces expression of glycolytic genes. J. Biol. Chem. 270: 31255-31261.
32. MINVIELLE-SEBASTIA, L., K. BF.YF.R, A. M. KRECIC, R. E. HECTOR, M. S. SWANSON el al. 1998 Control of cleavage site selection during mRNA 3' end formation by a single yeast hnRNP. EMBO J. 17: 7454-7468.
33. MISTELI, T., and D. I. SPECTOR, 1999 RNA polymcrase II targets pre-mRNA splicing factors to transcription sites in vivo. Mol. Cell 3: 697-705.
34. MORTILLARO, M.J., B.J. BLENCOWE, X. WEI, H. NAKAYASU, L. Du et al. 1996 A hyperphosphorylatcd form of the large subunit of RNA polymerasc II is associated with splicing complexes and the nuclear matrix. Proc. Natl. Acad. Sei. USA 93: 8253-8257.
35. MüHLRAD, D., R. HUNTER and R. PARKER, 1992 A rapid method for localized mutagenesis of yeast genes. Yeast 8: 79-82.
36. MYER, V. E., and R. A. YOUNG, 1998 RNA polymerasc II holoenzymes and siibcomplcxes. J. Biol. Chem. 273: 27757-27760.
37. NONET, M., D. SWEF.TSER and R. A. YOUNG, 1987 Functional redundancy and structural polymorphism in the large subunit of RNA polymerase II. Cell 50: 909-915.
38. PATTURAJAN, M., R. J. SCHULTE, B. M. SEKTON, R. BEREZNEY, M. VINCENT el al. 1998a Growth-related changes in phosphorylation of yeast RNA polymerase II. J. Biol. Clicm. 273: 4689-4694.
39. PATTURAJAN, M., X. Y. WEI, R. BEREZNEY and J. L. CORDEN, 1998b A nuclear matrix protein interacts with the phosphor) lated C-tcrminal domain of RNA polymerase II. Mol. Cell. Biol.18: 2406-2415.
40. PENG, J., M. Liu, J. MARION, Y. ZHU and D. H. PRICE, 1998a RNA polymerasc II elongation control. Cold Spring Harbor Symp. Quant. Biol. 63: 365-370.
41. PENG.J., Y. Znu,J. T. MILTON and D. H. PRICE, 1998b Identification of multiple cyclin subunits of human P-TF.Fb. Genes Dev. 12:755-762.
42. PlLLUTLA, R. C., Z. YUE, E. MALDONADO and A. J. SlIATKIN, 1998 Re-combinant human mRNA cap methyltransfcrase binds capping cnzyme/RNA polymerase Ho complexes. J. Biol. Chem. 273: 21443-21446.
43. ROSE, M. D., F. WINSTON and P. HIETER, 1990 Methods in Yeast Genetics: A iMboratory Course Manual. Cold Spring Harbor Iiboratory Press, Cold Spring Harbor, NY.
44. SCAFE, C., M. NONET and R. A. YOUNG, 1990 RNA polymerase II mutants defective in transcription of a subset of genes. Mol. Cell. Biol. 10: 1010-1016.
45. SCIIIESTL, R. H., and R. D. GIETJ., 19S9 High efficiency transformation of intact yeast cells using single stranded nucleic acids as a carrier. Curr. Genet. 16: 339-346.
46. SIKORSKI, R. S., and P. HIETER, 1989 A system of shuttle vectors and yeast host strains designed for efficient manipulation of DNA in Saccharomyces cerevisiae. Genetics 122: 19-27.
47. SIOMI, H., and G. DREYFUSS, 1997 RNA-binding proteins as regulators of gene expression. Curr. Opin. Genet. Dev. 7: 345-353.
48. STEINMETZ, E. J., 1997 Prc-mRNA processing and the CTD of RNA polymerase II: the tail that wags the dog? Cell 89: 491-494.
49. STEINMETZ, E.J., and D. A. BROW, 1996 Repression of gene expression by an exogenous sequence clement acting in concert with a heterogeneous nuclear ribonucleoprotcin-Iike protein, Nrdl, and the putative hclicasc Scnl. Mol. Cell. Biol. 16: 6993-7003.
50. STEINMETZ, E. J., and D. A. BROW, 1998 Control of pre-mRNA accumulation by the essential yeast protein Nrdl requires highaffinity transcript binding and a domain implicated in RNA polymerase II association. Proc. Nad. Acad. Sei. USA 95: CG99-6704.
51. STERNER, D. E., J. M. LEE, S. E. HARDIN and A. L. GREENI.EAF, 1995 The yeast carboxyl-terminal repeat domain kinase CTDK-I is a divergent cyclin-cyclin-dcpendent kinase complex. Mol. Cell. Biol. 15: 5716-5724.
52. SUGIMOTO, K., K. MATSUMOTO, R. D. KORNBERG, S. I. REED and C. WITTENBERG, 1995 Dosage suppressors of the dominant Gl cyclin mutant CLN3-2: identification of a yeast gene encoding a putative RNA/ssDNA binding protein. Mol. Gen. Genet. 248: 712-718.
53. TYERS, M., G. TOKIWA, R. NASH and B. FUTCIIER, 1992 The ClnSCdc28 kinase complex of S. cerevisiae is regulated by proteolysis and phosphorylation. E.MI5OJ. 11: 1773-1784.
54. 'ADA, T., T. TAKAGI, Y. YAMAGUCHI, A. FERDOUS, T. I.MAI et al. 1998a DSIF, a novel transcription elongation factor that regulates RNA polymerasc II processivity, is composed of human Spt4 and Spt5 homologs. Genes Dcv. 12: 343-356.
55. WADA, T., T. TAKAGI, Y. YAMAGUCHI, D. WATANABE and H. HANDA, 1998b Eidcncc that P-TEFb alleviates the negative effect of DSIF on RNA polymerasc II-depcndent transcription in vitro. EMBOJ. 17: 7395-7403.
56. WEI, P., M. E. GARBER, S. FANG, W. H. FISCHER and K. A.JONES, 1998 A novel CDK9-associatcd C-typc cyclin interacts directly with HIV- 1 tat and mediates its high-affinity, loop-specific binding to TARRNA. Cell 92: 451-462.
57. WEST, M. L., andj. L. CORDEN, 1995 Construction and analysis of yeast RNA polymerasc II CTD deletion and substitution mutants. Genetics 140: 1223-1233.
58. WILSON, I. A., H. L. NIMAN, R. A. HOUGHTEN, A. R. CIIERENSON, M. L. COXXOLLV et al. 1984 The structure of an antigenic determinant in a protein. Cell 37: 7G7-778.
59. WILSON, S. M., K. V. DATAR, M. R. PADDY, J. R. SwF.ni.ow and M. S. SWANSON, 1994 Characterization of nuclear polyadcnylatcd RNA-binding proteins in Saccharomyres cemisiae.J. Cell Biol. 127: 1173-1184.
60. YAMAGUCHI, Y., T. TAKAGI, T. WADA, K. YANO, A. FURUVA et ni. 1999 NEI.F, a multisubunit complex containing RD, cooperates with DSIF to repress RNA polymerase II elongation. Cell 97: 41-51.
61. YUE, Z., E. MALDONADO, R. PILLUTLA, H. Ciio, D. REINBERG et al. 1997 Mammalian capping enzyme complements mutant Sarcharomyces cerevisiae lacking mRNA guanylyltransferase and selectively binds the elongating form of RNA polymcrase II. Proc. Nad. Acad. Sei. USA 94: 12898-12903.
62. YURYF.V, A., and J. L. CORDEN, 1996 Suppression analysis reveals a functional difference between the serines in positions two and five in the consensus sequence of the C-terminal domain of yeast RNA polymerasc II. Genetics 143: 661-671.
63. YURVEV, A., M. PATTURAJAN, Y. LITINGTUNG, R. V.Josin, C. GENTILE elal. 1996 The C-tcrminal domain of the largest subunit of RNA polymerase II interacts with a novel set of scrine/argininc-rich proteins. Proc. Nad. Acad. Sei. USA 93: 6975-6980.
64. ZHU, Y., T. PE'ERV, J. PENG, Y. RAMANATIUN, N. MARSHALL, el al. 1997 Transcription elongation factor P-TEFb is required for HIV-1 Tat transactivation in vitro. Genes Dev. 11: 2622-2632.