Extent and role of multisegmental coupling in the lamprey spinal locomotor pattern generator

Journal of Neurophysiology

Volumn 83, Issue 1, 2000, Pages 465-476

  Miller, William L ^a   Sigvardt, Karen A ^a,b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; INTERNEURON; LAMPREY; LOCOMOTION; MOTOR PERFORMANCE; NERVE CONDUCTION; NONHUMAN; OSCILLATION; PRIORITY JOURNAL; SPINAL CORD;

EID: 0033973303     PISSN: 00223077     EISSN: None     Source Type: Journal    
DOI: 10.1152/jn.2000.83.1.465     Document Type: Article

References (82)

1. BERRY, M. S. AND PENTREATH, V. W. Criteria for distinguishing between monosynaptic and polysynaptic transmission. Brain Res. 105: 1-20, 1976.
2. BUCHANAN, J. T. Identification of interneurons with contralateral, caudal axons in the lamprey spinal cord: synaptic interactions and morphology. J. Neurophysiol. 47: 961-975, 1982.
3. BUCHANAN, J. T. Neural network simulations of coupled locomotor oscillators in the lamprey spinal cord. Biol. Cybern. 66: 367-374, 1992.
4. BUCHANAN, J. T. Electrophysiological properties of identified classes of lamprey spinal neurons. J. Neurophysiol. 70: 2313-2325, 1993.
5. BUCHANAN, J. T. Lamprey spinal interneurons and their roles in swimming activity. Brain Behav. Evol. 48: 287-296, 1996.
6. BUCHANAN, J. T. AND COHEN, A. H. Activities of identified interneurons, motoneurons, and muscle fibers during fictive swimming in the lamprey and effects of reticulospinal and dorsal cell stimulation. J. Neurophysiol. 47: 948-960, 1982.
7. BUCHANAN, J. T. AND GRILLNER, S. A new class of small inhibitory interneurones in the lamprey spinal cord. Brain Res. 438: 404-407, 1988.
8. BUCHANAN, J. T. AND MCPHERSON, D. R. The neuronal network for locomotion in the lamprey spinal cord - evidence for the involvement of commissural interneurons. J. Physiol. (Paris) 89: 221-233, 1995.
9. BUCHANAN, J. T., GRILLNER, S., CULLHEIM, S., AND RISLING, M. Identification of excitatory interneurons contributing to generation of locomotion in lamprey: structure, pharmacology, and function. J. Neurophysiol. 62: 59-69, 1989.
10. BUCHANAN, J. T., KASICKI S, AND KOMOROWSKI, D. Swim oscillator coupling signals in the lamprey spinal cord. Soc. Neurosci. Abstr. 22: 687, 1996.
11. CALABRESE, R. L. Oscillation in motor pattern-generating networks. Curr. Opin. Neurobiol. 5: 816-823, 1995.
12. COHEN, A. H. Intersegmental coordinating system of the lamprey central pattern generator for locomotion. J. Comp. Physiol. A Sens. Neural Behav. Physiol. 160: 181-193, 1987a.
13. COHEN, A. H. Effects of oscillator frequency on phase-locking in the lamprey central pattern generator. J. Neurosci. Methods 21: 113-125, 1987b.
14. COHEN, A. H., AND KIEMEL, T. Intersegmental coordination: lessons from modeling systems of coupled non-linear oscillators. Am. Zool. 33: 54-65, 1993.
15. COHEN, A. H., AND WALLÉN, P. The neural correlate of locomotion in fish. "Fictive swimming" induced in an in vitro preparation of the lamprey spinal cord. Exp. Brain Res. 41: 11-18, 1980.
16. COHEN, A. H., BAKER, M. T., AND DOBROV, T. A. Evidence for functional regeneration in the adult lamprey spinal cord following transection. Brain Res. 496: 368-372, 1989.
17. COHEN, A. H., ERMENTROUT, G. B., KIEMEL, T., KOPELL, N., SIGVARDT, K. A., AND WILLIAMS, T. L. Modelling of intersegmental coordination in the lamprey central pattern generator for locomotion. Trends Neurosci. 15: 434-438, 1992.
18. COHEN, A. H., HOLMES, P. J., AND RAND, R. H. The nature of the coupling between segmental oscillators of the lamprey spinal generator for locomotion: a mathematical model. J. Math. Biol. 13: 345-369, 1982.
19. COHEN, A. H., LESHER, S., PATE, V., GUAN, L., AND KIEMEL, T. Studies of the stability of the swimming rhythm in lampreys. Soc. Neurosci. Abstr. 21: 687, 1995.
20. COHEN, A. H., ROSSIGNOL, S., GRILLNER, S., EDS. Neural Control of Rhythmic Movements in Vertebrates. New York: Wiley, 1988.
21. GRAHAM-BROWN, T. The intrinsic factors in the act of progression in the mammal. Proc. R. Soc. Lond. B. Biol. Sci. 84: 308-319, 1911.
22. GRAY, C. M. Rhythmic activity in neuronal systems: insights into integrative function. In: 1992 Lectures in Complex Systems, edited by L. Nadel and D. Stein, New York: Addison-Wesley. 1993, p. 89-161.
23. GRAY, C. M. Synchronous oscillations in neuronal systems: mechanisms and functions. J. Comput. Neurosci. 1: 11-38, 1994.
24. GREENHOUSE, S. W. AND GEISSER, S. On methods in the analysis of profile data. Psychometrika 24: 95-112, 1959.
25. GRILLNER, S. AND WALLÉN, P. Central pattern generators for locomotion, with special reference to vertebrates. Annu. Rev. Neurosci. 8: 233-61, 1985.
26. GRILLNER, S. AND ZANGGER, P. Locomotor movements generated by the deafferented spinal cord., Acta Physiol. Scand. 91: 38-39A, 1974.
27. GRILLNER, S. AND ZANGGER, P. On the central generation of locomotion in the low spinal cat. Exp. Brain Res. 342: 241-61, 1979.
28. GRILLNER, S., BUCHANAN, J. T., LANSNER, A. Simulation of the segmental burst generating network for locomotion in lamprey. Neurosci. Lett. 89: 31-35, 1988.
29. GRILLNER, S., MCCLELLAN, A., AND PERRET, C. Entrainment of the spinal pattern generators for swimming by mechano-sensitive elements in the lamprey spinal cord in vitro. Brain Res. 217: 380-386, 1981.
30. GRILLNER, S., WALLÉN, P., BRODIN, L., AND LANSNER, A. Neuronal network generating locomotor behavior in lamprey: circuitry, transmitters, membrane properties, and simulation. Annu. Rev. Neurosci. 14: 169-199, 1991.
31. HAGEVIK, A., AND MCCLELLAN, A. D. Coupling of spinal locomotor networks in larval lamprey revealed by receptor blockers for inihibitory amino acids: neurophysiology and computer modeling. J. Neurophysiol. 72: 1810-1828, 1994.
32. HARRIS-WARRICK, R. M., COHEN, A. H. Serotonin modulates the central pattern generator for locomotion in the isolated lamprey spinal cord. J. Exp. Biol. 116: 27-46, 1985.
33. HARRIS-WARRICK, R. M., MARDER, I., SELVERSTON, A. I., AND MOULINS, M. (Editors). Dynamic Biological Networks: The Stomatogastric Nervous System. Cambridge, MA: MIT Press, 1992.
34. HELLGREN, J., GRILLNER, S., AND LANSNER, A. Computer simulation of the segmental neural network generating locomotion in lamprey by using populations of network interneurons. Biol. Cybern. 68: 1-13, 1992.
35. JACKLET, J. W. (Editor). Neuronal and Cellular Oscillators. Cellular Clock Series, Vol. 2. New York: Marcel Dekker, 1989.
36. KAHN, D., PACE-SCHOTT, E. F., AND HOBSON, J. A. Consciousness in waking and dreaming: the roles of neuronal oscillation and neuromodulation in determining similarities and differences. Neuroscience 78: 13-38, 1997.
37. KEMNITZ, C. P., STRAUSS, T. R., HOSFORD, D. M., AND BUCHANAN, J. T. Modulation of swimming in the lamprey, Petromyzon marinus, by serotonergic and dopaminergic drugs. Neurosci. Lett. 201: 115-118, 1995.
38. KIEMEL, T. Three Problems from the Mathematics of Neural Oscillations. (PhD dissertation). Ithaca, NY: Cornell Univ., 1990.
39. KOPELL, N. AND ERMENTROUT, G. B. Symmetry and phase coupling in chains of weakly coupled oscillators. Commun. Pure Appl. Math. 39: 623-660, 1986.
40. KOPELL, N. AND ERMENTROUT, G. B. Coupled oscillators and the design of central pattern generators. Math. Biosci. 90: 87-109, 1988.
41. KOPELL, N., ERMENTROUT, G. B. Phase transitions and other phenomena in chains of coupled oscillators. SIAM J. Appl. Math. 50: 1014-1052, 1990.
42. KOPELL, N., ERMENTROUT, G. B., AND WILLIAMS, T. L. On chains of oscillators forced at one end. SIAM J. Appl. Math. 51: 1397-1417, 1991.
43. KOPELL, N., ZHANG, W., AND ERMENTROUT, G. B. Multiple coupling in chains of oscillators. SIAM J. Math. Anal. 21: 935-953, 1990.
44. MARDER, E. From biophysics to models of network function. Annu. Rev. Neurosci. 21: 25-45, 1998.
45. MARDER, E. AND CALABRESE, R. L. Principles of rhythmic motor pattern generation. Physiol. Rev. 76: 687-717, 1996.
46. MATSUSHIMA, T. AND GRILLNER, S. Neural mechanisms of intersegmental coordination in lamprey: local excitability changes modify the phase cou-pling along the spinal cord. J. Neurophysiol. 67: 373-388, 1992a.
47. MATSUSHIMA, T. AND GRILLNER, S. Local serotonergic modulation of calcium-dependent potassium channels controls intersegmental coordination in the lamprey spinal cord. J. Neurophysiol. 67: 1683-1690, 1992b.
48. MCCLELLAN, A. D. Time course of locomotor recovery and functional regeneration in spinal cord-transected lamprey: in vitro preparations. J. Neurophysiol. 72: 847-860, 1994.
49. MCCLELLAN, A. D. AND SIGVARDT, K. A. Features of entrainment of spinal pattern generators for locomotor activity in the lamprey spinal cord. J. Neurosci. 8: 133-145, 1988.
50. MCPHERSON, D. R., BUCHANAN, J. T., AND KASICKI, S. Effects of strychnine on fictive swimming in the lamprey: evidence for glycinergic inhibition, discrepancies with model predictions, and novel modulatory rhythms. J. Comp. Physiol. A Sens. Neural Behav. Physiol. 175: 311-321, 1994.
51. MELLEN, N., KIEMEL, T., AND COHEN, A. H. Correlational analysis of fictive swimming in the lamprey reveals strong functional intersegmental coupling. J. Neurophysiol. 73: 1020-1030, 1995.
52. MILLER, W. L. Distributed Coupling and Network Performance: Studies of the Functional Role of Propriospinal Connections in the Lamprey Locomotor Central Pattern Generator (PhD dissertation). Davis, CA: Univ. of California, 1997.
53. MILLER, W. L. AND SIGVARDT, K. A. Effect of eliminating short-range coupling on intersegmental coordination in the lamprey locomotor central pattern generator. In: Proceedings of the International Symposium on Neurons, Networks, and Motor Behavior, edited by P.S.G. Stein, S. Grillner, A.I. Selverston, and D.G. Stuart. Tuscon, AZ: Univ. of Arizona, 1995, p. 41.
54. MILLER, W. L. AND SIGVARDT, K. A. Influence of multisegmental coordinating fibers on the rhythmicity of distant segments in the lamprey spinal central pattern generator. Soc. Neurosci. Abstr. 22: 1642, 1996.
55. MILLER, W. L. AND SIGVARDT, K. A. Spectral analysis of oscillatory neural circuits. J. Neurosci. Methods 80: 113-28, 1998.
56. MILLER, W. L., GORMLEY, K. M., WILLIAMS, T. L., AND SIGVARDT, K. A. Role of long-range coupling in intersegmental coordination: variability in properties of fictive locomotion depends on length of in vitro lamprey spinal cord preparation. In: Nervous Systems and Behavior. Proceedings of the Fourth International Congress of Neuroethology, edited by M. Burrows, T. Matheson, P.L. Newland, and H. Schuppe. New York: Verlag, 1995, p. 452.
57. O'BRIEN, R. G. AND KAISER, M. K. MANOVA method for analyzing repeated measures designs: an extensive primer. Psychol. Bull. 97: 316-333, 1985.
58. PEARCE, R. A. AND FRIESEN, W. O. A model for intersegmental coordination in the leach nerve cord. Biol. Cybern. 58: 301-311, 1988.
59. POON, M.L.T. Introduction of swimming in lamprey in L-DOPA and amino acids. J. Comp. Physiol. A Sens. Neural Behav. Physiol. 136: 337-344, 1980.
60. RITZ, R. AND SEJNOWSKI, T. J. Synchronous oscillatory activity in sensory systems: new vistas on mechanisms. Curr. Opin. Neurobiol. 7: 536-46, 1997.
61. ROSENBERG, J. R., AMJAD, A. M., BREEZE, P., BRILLINGER, D. R., AND HALLIDAY, D. M. The Fourier approach to the identification of functional coupling between neuronal spike trains. Prog. Biophys. Mol. Biol. 53: 1-31, 1989.
62. ROVAINEN, C. M. Effects of groups of propriospinal interneurons on fictive swimming in the isolated spinal cord of the lamprey. J. Neurophysiol. 54: 959-977, 1985.
63. SELVERSTON, A. I., RUSSELL, D. F., MILLER, J. P., AND KING, D. G. The stomatogastric nervous system: structure and function of a small neural network. Prog. Neurobiol. 7: 215-289, 1976.
64. SHERRINGTON, C. S. The Integrative Action of the Nervous System. New Haven: Yale Univ. Press, 1906.
65. SHUMWAY, R. H. Applied Statistical Time Series Analysis. Englewood Cliffs, NJ: Prentice-Hall, 1988.
66. SIGVARDT, K. A. Spinal mechanisms in the control of lamprey swimming. Am. Zool. 29: 19-35, 1989.
67. SIGVARDT, K. A. AND MILLER, W. L. Analysis and modeling of the locomotor CPG as a network of coupled oscillators. Ann. NY Acad. Sci. 860: 250-265, 1998.
68. SIGVARDT, K. A. AND WILLIAMS, T. L. Effects of local oscillator frequency on intersegmental coordination in the lamprey locomotor CPG: theory and experiment. J. Neurophysiol. 76: 4094-4103, 1996.
69. SKINNER, F. K. AND MULLONEY, B. Intersegmental coordination in invertebrates and vertebrates. Curr. Opin. Neurobiol. 8: 725-732, 1998.
70. STERIADE, M. Synchronized activities of coupled oscillators in the cerebral cortex and thalamus at different levels of vigilance. Cereb Cortex. 7: 583-604, 1997.
71. TEGNÉR, J., MATSUSHIMA, T., EL MANIRA, A., AND GRILLNER, S. The spinal GABA system modulates burst frequency and intersegmental coordination in the lamprey: differential effects of GABAA and GABAB receptors. J. Neurophysiol. 69: 647-57, 1993.
72. TUNSTALL, M. J. AND ROBERTS, A. Longitudinal coordination of motor output during swimming in Xenopus embryos. Proc. R. Soc. Lond. B Biol. Sci. 244: 27-32, 1991.
73. TUNSTALL, M. J. AND ROBERTS, A. A longitudinal gradient of synaptic drive in the spinal cord of Xenopus embryos and its role in co-ordination of swimming. J. Physiol. (Lond.) 474: 393-405, 1994.
74. ULLSTRÖM, M., KOTALESKI, J. H., TEGNÉR, J., AURELL, E., GRILLNER, S., AND LANSNER, A. Activity-dependent modulation of adaptation produces a constant burst proportion in a model of the lamprey spinal locomotor generator. Biol. Cybern. 791: 1-14, 1998.
75. WADDEN, T., HELLGREN, J., LANSNER, A., AND GRILLNER, S. Intersegmental coordination in the lamprey: simulations using a network model without segmental boundaries. Biol. Cybern. 76: 1-9, 1997.
76. WALLÉN, P. AND WILLIAMS, T. L. Fictive locomotion in the lamprey spinal cord in vitro compared with swimming in the intact and spinal animal. J. Physiol. (Lond.) 347: 225-239, 1984.
77. WALLÉN, P., EKEBERG, O., LANSNER, A., BRODIN, L., TRAVEN, H., AND GRILLNER, S. A computer-based model for realistic simulations of neural networks. II. The segmental network generating locomotor rhythmicity in the lamprey. J. Neurophysiol. 68: 1939-1950, 1992.
78. WICKELGREN, W. O. Physiological and anatomical characteristics of reticulospinal neurones in lamprey. J. Physiol. (Lond.) 270: 89-114, 1977.
79. WILLIAMS, T. L. Phase coupling in simulated chains of coupled oscillators representing the lamprey spinal cord. Neural Comput. 4: 546-558, 1992a.
80. WILLIAMS, T. L. Phase coupling by synaptic spread in chains of coupled neuronal oscillators. Science 258: 662-665, 1992b.
81. WILLIAMS, T. L., SIGVARDT, K. A., KOPELL, N., ERMENTROUT, G. B., AND REMLER, M. P. Forcing of coupled nonlinear oscillators: studies of intersegmental coordination in the lamprey locomotor central pattern generator. J. Neurophysiol. 64: 862-871, 1990.
82. WILSON, D. M. The central nervous control of flight in a locust. J. Exp. Biol. 38: 471-490, 1961.