Further evidence for the heterogeneity of functional muscarinic receptors in guinea pig gallbladder

European Journal of Pharmacology

Volumn 388, Issue 1, 2000, Pages 115-123

  Akici, Ahmet ^a   Karaalp, Atila ^a   Iskender, Ece ^a   Christopoulos, Arthur ^b   El Fakahany, Esam E ^b   Oktay, Şule ^a  

^a MARMARA UNIVERSITY   (Turkey)

^b UNIVERSITY OF MINNESOTA   (United States)

Author keywords

Ca2+; Extracellular; Gallbladder; Guinea pig; Intracellular; Kinetics; Muscarinic receptor; Radioligand binding; Receptor heterogeneity; Sr2+

Indexed keywords

ATROPINE; CALCIUM; CARBACHOL; METHOCTRAMINE; METHYLSCOPOLAMINE; MUSCARINIC M1 RECEPTOR; MUSCARINIC M2 RECEPTOR; MUSCARINIC M3 RECEPTOR; MUSCARINIC M4 RECEPTOR; MUSCARINIC M5 RECEPTOR; MUSCARINIC RECEPTOR; PIRENZEPINE; RADIOLIGAND; RECEPTOR SUBTYPE; STRONTIUM; TRIPITRAMINE;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BLADDER; CALCIUM CELL LEVEL; CHO CELL; CONTROLLED STUDY; DRUG RECEPTOR BINDING; FEMALE; GALLBLADDER; GUINEA PIG; KINETICS; MALE; NONHUMAN; PRIORITY JOURNAL; SMOOTH MUSCLE CONTRACTION; TISSUE HOMOGENATE;

ANIMALS; CALCIUM; CELL MEMBRANE; CHO CELLS; CRICETINAE; FEMALE; GALLBLADDER; GUINEA PIGS; HUMANS; MALE; MUSCARINIC AGONISTS; MUSCARINIC ANTAGONISTS; MUSCLE CONTRACTION; MUSCLE, SMOOTH; N-METHYLSCOPOLAMINE; PARASYMPATHOLYTICS; RADIOLIGAND ASSAY; RECEPTORS, MUSCARINIC; URINARY BLADDER;

EID: 0033972886     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-2999(99)00832-8     Document Type: Article

References (46)

1. 2 muscarinic receptor subtype coupled to both adenylate cyclase and phosphoinositide turnover. Science. 238:1987;672-675.
2. Baba K., Kawanishi M., Satake T., Tomita T. Effects of verapamil on the concentrations of guinea pig trachea muscle induced by calcium, strontium and barium. Br. J. Pharmacol. 84:1985;203-211.
3. Barocelli E., Ballabeni V., Chiavarini M., Molina E., Impicciatore M. Functional comparison between nuvenzepine and pirenzepine on different guinea pig isolated smooth muscle preparations. Pharmacol. Res. 30:1994;161-170.
4. Bradford M. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem. 72:1976;248-254.
5. Brown A.M., Birnbaumer L. Direct G protein gating of ion channels. Am. J. Physiol. 254:1988;H401-H410.
6. Brown J.H., Brown S.L. Agonists differentiate muscarinic receptors that inhibit cAMP formation from those that stimulate phosphoinositide metabolism. J. Biol. Chem. 259:1984;3777-3781.
7. Buckley N.J., Bonner T.I., Buckley C.M., Brann M.R. Antagonist binding properties of five cloned muscarinic receptors expressed in CHO-K1 cells. Mol. Pharmacol. 35:1989;469-476.
8. Caufield M.P., Birdsall N.J.M. International Union of Pharmacology: XVII. Classification of muscarinic acetylcholine receptors. Pharmacol. Rev. 50:1998;279-290.
9. Chen Q., Yu P., De Petris G., Biancani P., Behar J. Distinct muscarinic receptors and signal transduction pathways in gallbladder muscle. J. Pharmacol. Exp. Ther. 273:1995;650-655.
10. 3 muscarinic receptors in rat parotid gland couple to two second messenger systems. Am. J. Physiol. 30:1991;1063-1073.
11. Doods H.N., Willim K.D., Boddeke H.W.G.M., Entzeroth M. Characterization of binding profiles of five cloned human muscarinic receptor subtypes. J. Pharmacol. Exp. Ther. 256:1993;727-733.
12. Dörje F., Wess J., Lambrecht G., Tacke R., Mutschler E., Brann M.R. Antagonist muscarinic receptors in guinea pig uterus. Eur. J. Pharmacol. 250:1991;223-230.
13. Eglen R.M., Hegde S.S., Watson N. Muscarinic receptor subtypes and smooth muscle function. Pharmacol. Rev. 48:1996;531-565.
14. Eglen R.M., Michel A.D., Levine W.B., Whiting R.L. Analysis of muscarinic receptors in guinea pig estrogen-dominated uterus, in vitro. Br. J. Pharmacol. 104:1991;. 44 pp.
15. Eglen R.M., Michel A.D., Whiting R.L. Characterization of the muscarinic receptor subtype mediating contractions of the guinea pig uterus. Br. J. Pharmacol. 96:1989;497-499.
16. Eglen R.M., Reddy H., Watson N., Challiss R.A.J. Muscarinic acetylcholine receptor subtypes in smooth muscle. Trends Pharmacol. Sci. 15:1994;114-119.
17. Eglen R.M., Whiting R.L. Heterogeneity of vascular muscarinic receptors. J. Auton. Pharmacol. 10:1990;233-245.
18. 4 receptors? Eur. J. Pharmacol. 332:1997;77-87.
19. 3H]AF-DX 384 to rat ileal smooth muscle muscarinic receptors. Recept. Res. 11:1991;141-152.
20. Felder C.C. Muscarinic acetylcholine receptors: signal transduction through multiple effectors. FASEB J. 9:1995;619-625.
21. 3 muscarinic receptor subtypes in primate brain. Synapse. 14:1993;283-296.
22. Flynn D.D., Reever C.M., Ferrari-Dileo G. Pharmacological strategies to selectively label and localize muscarinic receptor subtypes. Drug Dev. Res. 40:1997;104-116.
23. Ford A.P.D.W., Levine W.B., Baxter G.S., Harris G.C., Eglen R.M., Whiting R.L. Pharmacological, biochemical and molecular characterization of muscarinic receptors in the guinea pig ileum: a multidisciplinary study. Mol. Neuropharmacol. 1:1991;117-127.
24. Gil D.W., Wolfe B.B. Pirenzepine distinguishes between muscarinic receptor-mediated phosphoinositide breakdown and inhibition of adenylate cyclase. J. Pharmacol. Exp. Ther. 232:1985;608-616.
25. Giraldo E., Monferini E., Ladinsky H., Hammer R. Muscarinic receptor heterogeneity in guinea pig intestinal smooth muscle: binding studies with AF-DX 116. Eur. J. Pharmacol. 141:1987;475-477.
26. Hulme E.C., Birdsall N.J.M., Buckley N.J. Muscarinic receptor subtypes. Annu. Rev. Pharmacol. Toxicol. 30:1990;633-673.
27. Karaalp A., Akici A., Akbulut H., Ulusoy N.B., Oktay Ş. Distinct functional muscarinic receptors in guinea pig gallbladder, ileum and atria. Pharmacol. Res. 39:1999;389-395.
28. Lee K.Y., Biancani P., Behar J. Calcium stores utilized by cholecystokinin and acetylcholine in the cat gallbladder muscle. Am. J. Physiol. 256:1989;G785-G788.
29. Leiber D., Sylvie M., Harbon S. Pharmacological evidence for distinct muscarinic subtypes coupled to the inhibition of adenylate cyclase and to the increased generation of inositol phosphates in the guinea pig myometrium. J. Pharmacol. Exp. Ther. 252:1990;800-809.
30. Maeda A., Kubo T., Mishina M., Numa S. Tissue distribution of mRNAs encoding muscarinic acetylcholine receptor subtypes. FEBS Lett. 239:1988;339-342.
31. Michel A.D., Delmondo R., Stefanish E., Whiting R.L. Binding characteristics of the muscarinic receptor subtype of the NG108-15 cell line. Naunyn-Schmiedeberg's Arch. Pharmacol. 340:1989;62-67.
32. 2 muscarinic receptors in longitudinal ileal smooth muscle membranes. Eur. J. Pharmacol. 145:1988;305-311.
33. 4 receptors in guinea pig gallbladder smooth muscle. J. Auton. Pharmacol. 18:1998;195-204.
34. 4 subtype? Pharmacology. 46:1993;308-314.
35. Parkman H.P., Pagano A.P., Ryan J.P. Subtypes of muscarinic receptors regulating gallbladder cholinergic contractions. Am. J. Physiol. 1999;. (in press).
36. Peralta E.G., Ashkenazi A., Winslow J.W., Ramachandran J., Capon D.J. Differential regulation of PI hydrolysis and adenylyl cyclase by muscarinic receptor subtypes. Nature. 334:1988;434-437.
37. Renzetti L.M., Wang M.B., Ryan J.P. Contribution of intracellular calcium to gallbladder smooth muscle contraction. Am. J. Physiol. 259:1990;G1-G5.
38. Somlyo A.V., Somlyo A.P. Strontium accumulation by sarcoplasmic reticulum and mitochondria in vascular smooth muscle. Science. 174:1971;955-958.
39. 1 muscarinic receptors mediate both adenylate cyclase inhibition and phosphoinositide turnover. EMBO J. 7:1988;3031-3035.
40. 3 receptor in guinea pig gallbladder. Am. J. Physiol. 267:1994;G523-G528.
41. Van Charldorp K.J., Van Zwieten P.A. Comparison of the muscarinic receptors in the coronary artery, cerebral artery and atrium of the pig. Naunyn-Schmiedeberg's Arch. Pharmacol. 339:1989;403-408.
42. Von Schrenck T., Mackensen B., Mende U., Schmitz W., Sievers J., Mirau S., Raedler A., Greten H. Signal transduction pathway of the muscarinic receptors mediating gallbladder contraction. Naunyn-Schmiedeberg's Arch. Pharmacol. 349:1994;346-354.
43. Von Schrenck T., Sievers J., Mirau S., Raedler A., Greten H. Characterization of muscarinic receptors on guinea pig gallbladder smooth muscle. Gastroenterology. 105:1993;1341-1349.
44. Wang P., Luthin G.R., Ruggieri M.R. Muscarinic acetylcholine receptor subtypes mediating urinary bladder contractility and coupling to GTP binding proteins. J. Pharmacol. Exp. Ther. 273:1995;959-966.
45. + on contraction-relaxation cycle in canine stomach. Comp. Biochem. Physiol., A: Comp. Physiol. 78A:1984;35-41.
46. Zhang L., Buxton I.L.O. Muscarinic receptors in canine colonic circular smooth muscle: II. Signal transduction pathways. Mol. Pharmacol. 40:1991;952-959.