Mild hypothermia reduces penumbral glutamate levels in the rat permanent focal cerebral ischemia model

Neurosurgery

Volumn 38, Issue 6, 1996, Pages 1216-1222

  Winfree, Christopher J ^a   Baker, Christopher J ^a   Connolly Jr , E Sander ^a   Fiore, Amory J ^a   Solomon, Robert A ^a  

^a NEUROLOGICAL INSTITUTE   (United States)

Author keywords

Glutamate; Hypothermia; Ischemia; Penumbra; Rat

Indexed keywords

GLUTAMIC ACID;

ANIMAL MODEL; ARTICLE; BRAIN BLOOD FLOW; BRAIN INFARCTION; BRAIN ISCHEMIA; BRAIN PROTECTION; CONTROLLED STUDY; INDUCED HYPOTHERMIA; MALE; MICRODIALYSIS; MIDDLE CEREBRAL ARTERY OCCLUSION; NONHUMAN; PRIORITY JOURNAL; RAT;

ANIMALS; CEREBRAL INFARCTION; DIFFUSION; EXTRACELLULAR SPACE; GLUTAMIC ACID; HYPOTHERMIA, INDUCED; MALE; MICRODIALYSIS; RATS; RATS, WISTAR;

EID: 0030000985     PISSN: 0148396X     EISSN: None     Source Type: Journal    
DOI: 10.1097/00006123-199606000-00034     Document Type: Article

References (56)

1. Allison LA, Mayer GS, Shoup RE: o-Phthalaldehyde derivatives of amines for high-speed liquid chromatography/electrochemistry. Anal Chem 56:1089-1096, 1984.
2. Arai H, Uto A, Ogawa Y, Sato K: Effects of low temperature on glutamate-induced intracellular calcium accumulation and cell death in cultured hippocampal neurons. Neurosci Lett 163:132-134, 1993.
3. Baker CJ, Fiore AJ, Frazzini VI, Choudhri TF, Zubay GP, Solomon RA: Intraischemic hypothermia decreases the release of glutamate in the cores of permanent focal cerebral infarcts. Neurosurgery 36:994-1002, 1995.
4. Baker CJ, Onesti ST, Barth KNM, Prestigiacomo CJ, Solomon RA: Hypothermic protection following middle cerebral artery occlusion in the rat. Surg Neurol 36:175-180, 1991.
5. Baker CJ, Onesti ST, Solomon RA: Reduction by delayed hypothermia of cerebral infarction following middle cerebral artery occlusion in the rat: A time course study. J Neurosurg 77:438-492, 1992.
6. Bederson JB, Pitts LH, Germano SM, Nishimura MC, Davis RL, Bartkowski HM: Evaluation of 2,3,5-triphenyltetrazolium chloride as a stain for detection and quantification of experimental cerebral infarction in rats. Stroke 17:1304-1308, 1986.
7. Bederson JB, Schwartz A, Germano IM: Prediction of stroke size by acute changes in laser doppler flowmetry during middle cerebral artery occlusion. Stroke 25:270, 1994 (abstr).
8. Berntman L, Welsh FA, Harp JR: Cerebral protective effect of low-grade hypothermia. Anesthesiology 55:495-498, 1981.
9. Busto R, Globus MYT, Dietrich D, Martinez E, Valdes I, Ginsberg MD: Effect of mild hypothermia on ischemia-induced release of neurotransmitters and free fatty acids in rat brain. Stroke 20:904-910, 1989.
10. Butcher SP, Bullock R, Graham DI, McCulloch J: Correlation between amino acid release and neuropathologic outcome in rat brain following middle cerebral artery occlusion. Stroke 21:1727-1733, 1990.
11. Chen Q, Chopp M, Bodzin G, Chen H: Temperature modulation of cerebral depolarization during focal cerebral ischemia in rats: Correlation with ischemia injury. J Cereb Blood Flow Metab 13:389-394, 1993.
12. Chen H, Chopp M, VandeLinde AMQ, Dereski MO, Garcia JH, Welch KMA: The effects of post-ischemic hypothermia on the neuronal injury and brain metabolism after forebrain ischemia in the rat. J Neurosci 107:191-198, 1992.
13. Chen H, Chopp M, Welch KMA: Effect of mild hypothermia on the ischémie infarct volume after middle cerebral artery occlusion in the rat. Neurology 41:1133-1135, 1991.
14. Chen H, Chopp M, Zhang ZG, Garcia JH: The effect of hypothermia on transient middle cerebral artery occlusion in the rat. J Cereb Blood Flow Metab 12:621-628, 1992.
15. Choi DW: Glutamate neurotoxicity in cortical cell culture is calcium dependent. Neurosci Lett 58:293-297, 1985.
16. Choi DW, Maulucci-Gedde M, Kriegstein AR: Glutamate neurotoxicity in cortical cell culture. J Neurosci Lett 7:357-368, 1987.
17. Choi DW, Rothman SM: The role of glutamate neurotoxicity in hypoxic-ischemic neuronal death. Annu Rev Neurosci 13:171-182, 1990.
18. Churn SB, Taft WC, Billingsley MS, Blair RE, DeLorenzo RJ: Temperature modulation of ischemic neuronal death and inhibition of calcium-calmodulin-dependent protein kinase II in gerbils. Stroke 21:1715-1721, 1990.
19. Dietrich WD, Busto R, Alonso O, Globus YTM, Ginsberg MD: Intraischemic but not postischemic brain hypothermia protects chronically following global forebrain ischemia in rats. J Cereb Blood Flow Metab 13:541-549, 1993.
20. Dirnagl U, Kaplan B, Jacewicz M, Pulsinelli W: Continuous measurement of cerebral cortical blood flow by laser-doppler flowmetry in a rat stroke model. J Cereb Blood Flow Metab 9:589-596, 1989.
21. Dimagl U, Pulsinelli W: Autoregulation of cerebral blood flow in experimental focal brain ischemia. J Cereb Blood Flow Metab 10:327-336, 1990.
22. Folbergrova J, Memezawa H, Smith ML, Siesjo BK: Focal and perifocal changes in tissue energy state during middle cerebral artery occlusion in normo- and hyperglycemic rats. J Cereb Blood Flow Metab 12:25-33, 1992.
23. Frazzini VI, Winfree CJ, Choudri HF, Prestigiacomo CJ, Solomon RA: Mild hypothermia and MK-801 have similar but not additive degrees of cerebroprotection the rat permanent focal ischemia model. Neurosurgery 34:1040-1047, 1994.
24. Gill R, Andine P, Hillered L, Persson L, Hagberg H: The effect of MK-801 on cortical spreading depression in the penumbral zone following focal ischaemia in the rat. J Cereb Blood Flow Metab 12:371-379, 1992.
25. Ginsberg MD, Sternau LL, Globus MYT, Dietrich WD, Busto R: Therapeutic modulation of brain temperature: Relevance to ischemic brain injury. Cerebrovasc Brain Metab Rev 4:189-225, 1992.
26. Goto Y, Kassell NF, Hiramatsu K, Soleau SW, Lee KS: Effects of intraischemic hypothermia on cerebral damage in a model of reversible focal ischemia. Neurosurgery 32:980-985, 1993.
27. Hakim AM, Hogan MJ, Carpenter S: Time course of cerebral blood flow and histological outcome after focal cerebral ischemia in rats. Stroke 23:1138-1144, 1992.
28. Hillered L, Hallstrom A, Segersvard S, Perrson L, Ungerstedt U: Dynamics of extracellular metabolites in the striatum after middle cerebral artery occlusion in the rat monitored by intracerebral microdialysis. J Cereb Blood Flow Metab 9:607-616, 1989.
29. Hiramatsu K, Kassell NF, Lee KS: Thermal sensitivity of hypoxic responses in neocortical brain slices. J Cereb Blood Flow Metab 13:395-401, 1993.
30. Hossmann K-A: Viability thresholds and the penumbra of focal ischemia. Ann Neurol 36:557-565, 1994.
31. Illievich U, Zornow M, Choi K, Scheller M, Sternat M: Effects of hypothermic metabolic suppression on hippocampal glutamate concentrations after transient global cerebral ischemia. Anesth Analg 78:905-911, 1994.
32. Kader A, Brisman MH, Maraire N, Huh J, Solomon RA: The effect of mild hypothermia on permanent focal ischemia in the rat. Neurosurgery 31:1056-1061, 1992.
33. Kaplan B, Brint S, Tanabe J, Jacewicz M, Wang XJ, Pulsinelli W: Temporal thresholds for neocortical infarction in rats subjected to reversible focal ischemia. Stroke 22:1032-1039, 1991.
34. Kuluz JW, Gregory GA, Yu ACH, Chang Y: Selective brain cooling during and after prolonged global ischemia reduces cortical damage in rats. Stroke 23:1792-1797, 1992.
35. Leonov Y, Sterz F, Safar P, Radivsky A, Oku KI: Mild cerebral hypothermia during and after cardiac arrest improves neurologic outcome in dogs. J Cereb Blood Flow Metab 10:57-70, 1990.
36. Lo EH, Steinberg GK: Effects of hypothermia on evoked potentials, magnetic resonance imaging, and blood flow in focal ischemia in rabbits. Stroke 23:889-893, 1992.
37. Lo EH, Steinberg GK, Panahian N, Maidment NT, Newcomb R: Profiles of extracellular amino acid changes in focal cerebral ischaemia: Effects of mild hypothermia. Neurol Res 15:281-287, 1993.
38. Matsumoto K, Graf R, Rosner G, Shimada N, Heiss WD: Flow thresholds for extracellular purine catabolite elevation in cat focal ischemia. Brain Res 579:309-314, 1992.
39. Matsumoto K, Graf R, Rosner G, Taguchi J, Heiss WD: Elevation of neuroactive substances in the cortex of cats during prolonged focal ischemia. J Cereb Blood Flow Metab 13:586-594, 1993.
40. Memezawa H, Smith ML, Siesjo BK: Penumbral tissues salvaged by reperfusion following middle cerebral artery occlusion in rats. Stroke 23:552-559, 1992.
41. Mitani A, Kataoka K: Critical levels of extracellular glutamate mediating gerbil hippocampal delayed neuronal death during hypothermia: Brain microdialysis study. Neuroscience 42:661-670, 1991.
42. Morikawa E, Ginsberg MD, Dietrich D, Duncan RC, Kraydieh S, Globus MYT, Busto R: The significance of brain temperature in focal cerebral ischemia: Histopathological consequences of middle cerebral artery occlusion in the rat. J Cereb Blood Flow Metab 12:380-389, 1992.
43. Moyer DJ, Welsh FA, Zager EL: Spontaneous cerebral hypothermia diminishes focal infarction in rat brain. Stroke 23:1812-1816, 1992.
44. Obrenovitch TP, Urenjak J, Richards DA, Ueda Y, Curzon G, Symon L: Extracellular neuroactive amino acids in the rat brain striatum during ischaemia: Comparison between penumbral conditions and ischaemia with sustained anoxic depolarism. J Neurochem 61:178-186, 1993.
45. Onesti ST, Baker CJ, Sun PP, Solomon RA: Transient hypothermia reduces focal ischemia in the rat. Neurosurgery 29:369-373, 1991.
46. Orwar O, Li X, Andine P, Bergstrom CM, Hagberg H, Folestad S, Sandberg M: Increased intra- and extracellular concentrations of γ-glutamylglutamate and related dipeptides in the ischemic rat striatum: Involvement of glutamyl transpeptidase. J Neurochem 63:1371-1376, 1994.
47. Ridenour TR, Warner DS, Todd MM, McAllister AC: Mild hypothermia reduces infarct size resulting from temporary but not permanent focal ischemia in rats. Stroke 23:733-738, 1992.
48. Sano T, Drummond JC, Patel PM, Grafe MR, Watson JC, Cole DJ: A comparison of the cerebral protective effects of isoflurane and mild hypothermia in a model of incomplete forebrain ischemia in the rat. Anesthesiology 76:221-228, 1992.
49. Shimada N, Graf R, Rosner G, Heiss WD: Ischemia-induced accumulation of extracellular amino acids in cerebral cortex, white matter, and cerebrospinal fluid. J Neurochem 60:66-71, 1993.
50. Shimizu H, Graham SH, Chang LH, Mintorovitch J, James TL, Faden AI, Weinstein PR: Relationship between extracellular neurotransmitter amino acids and energy metabolism during cerebral ischemia in rats monitored by microdialysis and in vivo magnetic resonance spectroscopy. Brain Res 605:33-42, 1993.
51. Siesjo BK: Pathophysiology and treatment of focal cerebral ischemia: Part I - Pathophysiology. J Neurosurg 77:169-184, 1992.
52. Siesjo BK: Pathophysiology and treatment of focal cerebral ischemia: Part II - Mechanisms of damage and treatment. J Neurosurg 77:337-354, 1992.
53. Takagi K, Ginsberg MD, Globus MYT, Dietrich WD, Martinez E, Kraydieh S, Busto R: Changes in amino acid neurotransmitters and cerebral blood flow in the ischemic penumbral region following middle cerebral artery occlusion in the rat: Correlation with histopathology. J Cereb Blood Flow Metab 13:575-585, 1993.
54. Ueda Y, Obrenovitch TP, Lok SY, Sarna GS, Symon L: Efflux of glutamate produced by short ischemia of varied severity in rat striatum. Stroke 23:253-259, 1992.
55. Welsh FA, Sims RE, Harris VA: Mild hypothermia prevents ischemic injury in gerbil hippocampus. J Cereb Blood Flow Metab 10:557-563, 1990.
56. Widmann R, Miyazawa T, Hossmann KA: Protective effect of hypothermia on hippocampal injury after 30 minutes of forebrain ischemia in rats is mediated by postischemic recovery of protein synthesis. J Neurochem 61:200-209, 1993.