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Volumn 25, Issue 6, 1997, Pages 1037-1043

Comparative analysis of brain protection by N-methyl-D-aspartate receptor antagonists after transient focal ischemia in cats

Author keywords

Cerebral blood flow; CGS 19755; Excitatory amino acids; Middle cerebral artery occlusion; MK 801; NPC 17742; Sematosensory evoked potential

Indexed keywords

2 AMINO 4,5 (1,2 CYCLOHEXYL) 7 PHOSPHONOHEPTANOIC ACID; 4 PHOSPHONOMETHYLPIPECOLIC ACID; DIZOCILPINE; N METHYL DEXTRO ASPARTIC ACID RECEPTOR BLOCKING AGENT;

EID: 0030951354     PISSN: 00903493     EISSN: None     Source Type: Journal    
DOI: 10.1097/00003246-199706000-00022     Document Type: Article
Times cited : (14)

References (34)
  • 1
    • 0021847574 scopus 로고
    • Ischemia-induced shift of inhibitory and excitatory amino acids from intra- to extracellular compartments
    • Hagberg H, Lehmann A, Sandberg M, et al: Ischemia-induced shift of inhibitory and excitatory amino acids from intra- to extracellular compartments. J Cereb Blood Flow Metab 1985; 5:413-419
    • (1985) J Cereb Blood Flow Metab , vol.5 , pp. 413-419
    • Hagberg, H.1    Lehmann, A.2    Sandberg, M.3
  • 2
    • 0022620257 scopus 로고
    • Glutamate and the pathophysiology of hypoxic-ischemic brain damage
    • Rothman SM, Olney JW: Glutamate and the pathophysiology of hypoxic-ischemic brain damage. Ann Neurol 1986; 19:105-111
    • (1986) Ann Neurol , vol.19 , pp. 105-111
    • Rothman, S.M.1    Olney, J.W.2
  • 4
    • 0028897733 scopus 로고
    • Clinical experience with excitatory amino acid antagonist drugs
    • Muir KW, Lees KR: Clinical experience with excitatory amino acid antagonist drugs. Stroke 1995; 26: 503-513
    • (1995) Stroke , vol.26 , pp. 503-513
    • Muir, K.W.1    Lees, K.R.2
  • 5
    • 0026658553 scopus 로고
    • Repeated negative DC deflections in rat cortex following middle cerebral artery occlusion are abolished by MK-801: Effect on volume of ischemic injury
    • Iijima T, Mies G, Hossmann K-A: Repeated negative DC deflections in rat cortex following middle cerebral artery occlusion are abolished by MK-801: Effect on volume of ischemic injury. J Cereb Blood Flow Metab 1992; 12: 727-733
    • (1992) J Cereb Blood Flow Metab , vol.12 , pp. 727-733
    • Iijima, T.1    Mies, G.2    Hossmann, K.-A.3
  • 6
    • 0026554702 scopus 로고
    • The effect of MK-801 on cortical spreading depression in the penumbral zone following focal ischemia in the rat
    • Gill R, Andine P, Hillered L, et al: The effect of MK-801 on cortical spreading depression in the penumbral zone following focal ischemia in the rat. J Cereb Blood Flow Metab 1992; 12: 371-379
    • (1992) J Cereb Blood Flow Metab , vol.12 , pp. 371-379
    • Gill, R.1    Andine, P.2    Hillered, L.3
  • 7
    • 0027310151 scopus 로고
    • Characterization of the cerebroprotective efficacy of the competitive NMDA receptor antagonist CGP40116 in a rat model of focal cerebral ischemia: An in vivo magnetic resonance imaging study
    • Sauer D, Allegrini PR, Cosenti A, et al: Characterization of the cerebroprotective efficacy of the competitive NMDA receptor antagonist CGP40116 in a rat model of focal cerebral ischemia: An in vivo magnetic resonance imaging study. J Cereb Blood Flow Metab 1993; 13:595-602
    • (1993) J Cereb Blood Flow Metab , vol.13 , pp. 595-602
    • Sauer, D.1    Allegrini, P.R.2    Cosenti, A.3
  • 8
    • 0025142948 scopus 로고
    • Focal cerebral ischemia in the cat: Pretreatment with a competitive NMDA receptor antagonist, D-CPP-ene
    • Bullock R, Graham DI, Chen MH, et al: Focal cerebral ischemia in the cat: Pretreatment with a competitive NMDA receptor antagonist, D-CPP-ene. J Cereb Blood Flow Metab 1990; 10: 668-674
    • (1990) J Cereb Blood Flow Metab , vol.10 , pp. 668-674
    • Bullock, R.1    Graham, D.I.2    Chen, M.H.3
  • 9
    • 0026525958 scopus 로고
    • Acute improvement in histological outcome by MK-801 following focal ischemia and reperfusion in the cat independent of blood flow changes
    • Dezsi L, Greenberg JH, Hamar J, et al: Acute improvement in histological outcome by MK-801 following focal ischemia and reperfusion in the cat independent of blood flow changes. J Cereb Blood Flow Metab 1992; 12:390-399
    • (1992) J Cereb Blood Flow Metab , vol.12 , pp. 390-399
    • Dezsi, L.1    Greenberg, J.H.2    Hamar, J.3
  • 10
    • 0023873505 scopus 로고
    • Protective effect of the glutamate antagonist, MK-801, in focal cerebral ischemia in the cat
    • Ozyurt E, Graham DI, Woodruff GN, et al: Protective effect of the glutamate antagonist, MK-801, in focal cerebral ischemia in the cat. J Cereb Blood Flow Metab 1988; 8:138-143
    • (1988) J Cereb Blood Flow Metab , vol.8 , pp. 138-143
    • Ozyurt, E.1    Graham, D.I.2    Woodruff, G.N.3
  • 11
    • 0023694129 scopus 로고
    • Focal cerebral ischemia in the cat: Treatment with the glutamate antagonist MK-801 after induction of ischemia
    • Park CK, Nehls DG, Graham DI, et al: Focal cerebral ischemia in the cat: Treatment with the glutamate antagonist MK-801 after induction of ischemia. J Cereb Blood Flow Metab 1988; 8:757-762
    • (1988) J Cereb Blood Flow Metab , vol.8 , pp. 757-762
    • Park, C.K.1    Nehls, D.G.2    Graham, D.I.3
  • 12
    • 0027378588 scopus 로고
    • Pharmacological profile of NPC 17742, a potent, selective and competitive N-methyl-D-aspartate receptor antagonist
    • Ferkany JW, Hamilton GS, Patch RJ, et al: Pharmacological profile of NPC 17742, a potent, selective and competitive N-methyl-D-aspartate receptor antagonist. J Pharmacol Exp Ther 1993; 264:256-264
    • (1993) J Pharmacol Exp Ther , vol.264 , pp. 256-264
    • Ferkany, J.W.1    Hamilton, G.S.2    Patch, R.J.3
  • 13
    • 0028032883 scopus 로고
    • Competitive N-methyl-D-aspartate receptor blockade reduces brain injury following transient focal ischemia in cats
    • Nishikawa T, Kirsch JR, Koehler RC, et al: Competitive N-methyl-D-aspartate receptor blockade reduces brain injury following transient focal ischemia in cats. Stroke 1994; 25:2258-2264
    • (1994) Stroke , vol.25 , pp. 2258-2264
    • Nishikawa, T.1    Kirsch, J.R.2    Koehler, R.C.3
  • 14
    • 0027300760 scopus 로고
    • Delayed therapy of experimental ischemia with competitive N-methyl-D-aspartate antagonists in rabbits
    • Madden KP, Clark WM, Zivin JA: Delayed therapy of experimental ischemia with competitive N-methyl-D-aspartate antagonists in rabbits. Stroke 1993; 24:1068-1071
    • (1993) Stroke , vol.24 , pp. 1068-1071
    • Madden, K.P.1    Clark, W.M.2    Zivin, J.A.3
  • 15
    • 0025370516 scopus 로고
    • Consistency of cerebral blood flow and evoked potential alterations with reversible focal ischemia in cats
    • Matsumiya N, Koehler RC, Traystman RJ: Consistency of cerebral blood flow and evoked potential alterations with reversible focal ischemia in cats. Stroke 1990; 21:908-916
    • (1990) Stroke , vol.21 , pp. 908-916
    • Matsumiya, N.1    Koehler, R.C.2    Traystman, R.J.3
  • 16
    • 0025745048 scopus 로고
    • Conjugated superoxide dismutase reduces extent of caudate injury after transient focal ischemia in cats
    • Matsumiya N, Koehler RC, Kirsch JR, et al: Conjugated superoxide dismutase reduces extent of caudate injury after transient focal ischemia in cats. Stroke 1991; 22:1193-1200
    • (1991) Stroke , vol.22 , pp. 1193-1200
    • Matsumiya, N.1    Koehler, R.C.2    Kirsch, J.R.3
  • 17
    • 0017399067 scopus 로고
    • Blood flow measurements with radionuclide-labeled particles
    • Heymann MA, Payne BD, Hoffman JI, et al: Blood flow measurements with radionuclide-labeled particles. Prog Cardiovasc Dis 1977; 20:55-79
    • (1977) Prog Cardiovasc Dis , vol.20 , pp. 55-79
    • Heymann, M.A.1    Payne, B.D.2    Hoffman, J.I.3
  • 18
    • 0022870943 scopus 로고
    • Evaluation of 2,3,5-triphenyltetrazolium chloride as a stain for detection and quantification of experimental cerebral infarction in rats
    • Bederson JB, Pitts LH, Germano SM, et al: Evaluation of 2,3,5-triphenyltetrazolium chloride as a stain for detection and quantification of experimental cerebral infarction in rats. Stroke 1986; 17:1304-1308
    • (1986) Stroke , vol.17 , pp. 1304-1308
    • Bederson, J.B.1    Pitts, L.H.2    Germano, S.M.3
  • 19
    • 0025360658 scopus 로고
    • A reversible component of cerebral injury as identified by the histochemical stain 2,3,5-triphenyltetrazolium chloride (TTC)
    • Cole DJ, Drummond JC, Ghazal EA, et al: A reversible component of cerebral injury as identified by the histochemical stain 2,3,5-triphenyltetrazolium chloride (TTC). Acta Neuropathol (Berl) 1990; 80:152-155
    • (1990) Acta Neuropathol (Berl) , vol.80 , pp. 152-155
    • Cole, D.J.1    Drummond, J.C.2    Ghazal, E.A.3
  • 20
    • 0026549816 scopus 로고
    • Monoclonal leukocyte antibody (MoAb 60.3) does not decrease injury following transient focal cerebral ischemia in cats
    • Takeshima R, Kirsch JR, Koehler RC, et al: Monoclonal leukocyte antibody (MoAb 60.3) does not decrease injury following transient focal cerebral ischemia in cats. Stroke 1992; 23: 247-252
    • (1992) Stroke , vol.23 , pp. 247-252
    • Takeshima, R.1    Kirsch, J.R.2    Koehler, R.C.3
  • 21
    • 0026528715 scopus 로고
    • The acute effects of MK-801 on cerebral blood flow and tissue partial pressures of oxygen and carbon dioxide in conscious and alpha-chloralose anaesthetized rats
    • Roussel S, Pinard E, Seylaz J: The acute effects of MK-801 on cerebral blood flow and tissue partial pressures of oxygen and carbon dioxide in conscious and alpha-chloralose anaesthetized rats. Neuroscience 1992; 47:959-965
    • (1992) Neuroscience , vol.47 , pp. 959-965
    • Roussel, S.1    Pinard, E.2    Seylaz, J.3
  • 23
    • 0024338054 scopus 로고
    • Pathological changes induced in cerebrocortical neurons by phencyclidine and related drugs
    • Olney JW, Labruyere J, Price MT: Pathological changes induced in cerebrocortical neurons by phencyclidine and related drugs. Science 1989; 244: 1360-1362
    • (1989) Science , vol.244 , pp. 1360-1362
    • Olney, J.W.1    Labruyere, J.2    Price, M.T.3
  • 24
    • 0025786634 scopus 로고
    • MK-801 and ketamine induce heat shock protein HSP72 in injured neurons in posterior cingulate and retrosplenial cortex
    • Sharp FR, Jasper P, Hall J, et al: MK-801 and ketamine induce heat shock protein HSP72 in injured neurons in posterior cingulate and retrosplenial cortex. Ann Neurol 1991; 30:801-809
    • (1991) Ann Neurol , vol.30 , pp. 801-809
    • Sharp, F.R.1    Jasper, P.2    Hall, J.3
  • 25
    • 34547385285 scopus 로고
    • CGS 19755: Correlation of in vitro neuroprotection, protection against experimental ischemia and CSF levels in cerebrovascular surgery patients
    • Perez-Pinzon MA, Maier CM, Sun GH, et al: CGS 19755: Correlation of in vitro neuroprotection, protection against experimental ischemia and CSF levels in cerebrovascular surgery patients. Abstr. Stroke 1995; 26:27
    • (1995) Stroke , vol.26 , pp. 27
    • Perez-Pinzon, M.A.1    Maier, C.M.2    Sun, G.H.3
  • 26
    • 0028921447 scopus 로고
    • Safety and tolerability of the glutamate antagonist CGS 19755 (Selfotel) in patients with acute ischemic stroke. Results of a Phase IIa randomized trial
    • Grotta J, Clark W, Coull B, et al: Safety and tolerability of the glutamate antagonist CGS 19755 (Selfotel) in patients with acute ischemic stroke. Results of a Phase IIa randomized trial. Stroke 1995; 26:602-605
    • (1995) Stroke , vol.26 , pp. 602-605
    • Grotta, J.1    Clark, W.2    Coull, B.3
  • 27
    • 0027179773 scopus 로고
    • Neuroprotective effects of glutamate antagonists and extracellular acidity
    • Kaku DA, Giffard RG, Choi DW: Neuroprotective effects of glutamate antagonists and extracellular acidity. Science 1993; 260:1516-1518
    • (1993) Science , vol.260 , pp. 1516-1518
    • Kaku, D.A.1    Giffard, R.G.2    Choi, D.W.3
  • 28
    • 0026551820 scopus 로고
    • The effect of glutamate receptor blockade on anoxic depolarization and cortical spreading depression
    • Lauritzen M, Hansen AJ: The effect of glutamate receptor blockade on anoxic depolarization and cortical spreading depression. J Cereb Blood Flow Metab 1992; 12:223-229
    • (1992) J Cereb Blood Flow Metab , vol.12 , pp. 223-229
    • Lauritzen, M.1    Hansen, A.J.2
  • 29
    • 0028292193 scopus 로고
    • Pharmacologic reversal of acute changes in diffusion-weighted magnetic resonance imaging in focal cerebral ischemia
    • Lo EH, Matsumoto K, Pierce AR, et al: Pharmacologic reversal of acute changes in diffusion-weighted magnetic resonance imaging in focal cerebral ischemia. J Cereb Blood Flow Metab 1994; 14:597-603
    • (1994) J Cereb Blood Flow Metab , vol.14 , pp. 597-603
    • Lo, E.H.1    Matsumoto, K.2    Pierce, A.R.3
  • 30
    • 0027982155 scopus 로고
    • Extracellular glutamate during focal cerebral ischaemia in rats: Time course and calcium-dependency
    • Wahl F, Obrenovitch TP, Hardy AM, et al: Extracellular glutamate during focal cerebral ischaemia in rats: Time course and calcium-dependency. J Neurochem 1994; 63:1003-1011
    • (1994) J Neurochem , vol.63 , pp. 1003-1011
    • Wahl, F.1    Obrenovitch, T.P.2    Hardy, A.M.3
  • 31
    • 0024428827 scopus 로고
    • Protective effect of N-methyl-D-aspartate antagonists after focal cerebral ischemia in rabbits
    • Steinberg GK, Saleh J, Kunis D, et al: Protective effect of N-methyl-D-aspartate antagonists after focal cerebral ischemia in rabbits. Stroke 1989; 20:1247-1252
    • (1989) Stroke , vol.20 , pp. 1247-1252
    • Steinberg, G.K.1    Saleh, J.2    Kunis, D.3
  • 32
    • 0025123549 scopus 로고
    • MK-801 attenuates capillary bed compression and hypoperfusion following incomplete focal cerebral ischemia
    • Meyer FB, Anderson RE, Friedrich PF: MK-801 attenuates capillary bed compression and hypoperfusion following incomplete focal cerebral ischemia. J Cereb Blood Flow Metab 1990; 10: 895-902
    • (1990) J Cereb Blood Flow Metab , vol.10 , pp. 895-902
    • Meyer, F.B.1    Anderson, R.E.2    Friedrich, P.F.3
  • 33
    • 0025992317 scopus 로고
    • The effects of a competitive NMDA receptor antagonist (CGS-19755) on cerebral blood flow and pH in focal ischemia
    • Takizawa S, Hogan M, Hakim AM: The effects of a competitive NMDA receptor antagonist (CGS-19755) on cerebral blood flow and pH in focal ischemia. J Cereb Blood Flow Metab 1991; 11: 786-793
    • (1991) J Cereb Blood Flow Metab , vol.11 , pp. 786-793
    • Takizawa, S.1    Hogan, M.2    Hakim, A.M.3
  • 34
    • 0024460526 scopus 로고
    • Effect of the NMDA antagonist MK-801 on local cerebral blood flow in focal cerebral ischemia in the rat
    • Park CK, Nehls DG, Teasdale GM, et al: Effect of the NMDA antagonist MK-801 on local cerebral blood flow in focal cerebral ischemia in the rat. J Cereb Blood Flow Metab 1989; 9:617-622
    • (1989) J Cereb Blood Flow Metab , vol.9 , pp. 617-622
    • Park, C.K.1    Nehls, D.G.2    Teasdale, G.M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.