Peri-implantation lethality in mice lacking the Sm motif- containing protein Lsm4

Molecular and Cellular Biology

Volumn 20, Issue 3, 2000, Pages 1055-1062

  Hirsch, Emilio ^a,d   Oohashi, Toshitaka ^a   Ahmad, Marianne ^c   Stamm, Stefan ^b   Fässler, Reinhard ^a,c  

^a MAX PLANCK INSTITUTE OF BIOCHEMISTRY   (Germany)

^b MAX PLANCK INSTITUTE OF NEUROBIOLOGY   (Germany)

^c LUND UNIVERSITY   (Sweden)

^d UNIVERSITY OF TURIN   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

RIBONUCLEOPROTEIN;

ANIMAL CELL; ARTICLE; BLASTOCYST; CONTROLLED STUDY; GENE MUTATION; GENETIC TRANSFECTION; HOMOZYGOSITY; MOUSE; NIDATION; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN PROCESSING; REPORTER GENE; STEM CELL;

AMINO ACID SEQUENCE; ANIMALS; CELL LINE; CLONING, MOLECULAR; EMBRYO IMPLANTATION; EMBRYONIC AND FETAL DEVELOPMENT; FEMALE; FETAL DEATH; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GENES, REPORTER; HUMANS; MICE; MOLECULAR SEQUENCE DATA; PROMOTER REGIONS (GENETICS); RECOMBINANT FUSION PROTEINS; RESTRICTION MAPPING; RIBONUCLEOPROTEINS, SMALL NUCLEAR; RNA, SMALL NUCLEAR; SACCHAROMYCES CEREVISIAE; SCHIZOSACCHAROMYCES; SEQUENCE ALIGNMENT; SEQUENCE DELETION; SEQUENCE HOMOLOGY, AMINO ACID; STEM CELLS; TRANSCRIPTION, GENETIC; TRANSFECTION;

EID: 0033971940     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.20.3.1055-1062.2000     Document Type: Article

References (27)

1. Altschul, S. F., W. Gish, W. Miller, E. W. Myers, and D. J. Lipman. 1990. Basic local alignment search tool. J. Mol. Biol. 215:403-410.
2. Bloch, W., E. Forsberg, S. Lentini, C. Brakebusch, K. Martin, H. W. Krell, U. H. Weidle, K. Addicks, and R. Fässler. 1997. β1 integrin is essential for teratoma growth and angiogenesis. J. Cell Biol. 139:265-278.
3. Branlant, C., A. Krol, J. P. Ebel, E. Lazar, B. Haendler, and M. Jacob. 1982. U2 RNA shares a structural domain with U1, U4, and U5 RNAs. EMBO J. 1:1259-1265.
4. Cooper, M., L. H. Johnston, and J. D. Beggs. 1995. Identification and characterization of Uss1p (Sdb23p): a novel U6 snRNA-associated protein with significant similarity to core proteins of small nuclear ribonucleoproteins. EMBO J. 14:2066-2075.
5. Dean, W. L., A. C. Seufert, G. A. Schultz, R. S. Prather, C. Simerly, G. Schatten, D. R. Pilch, and W. F. Marzluff. 1989. The small nuclear RNAs for pre-mRNA splicing are coordinately regulated during oocyte maturation and early embryogenesis in the mouse. Development 106:325-334.
6. Fässler, R., and M. Meyer. 1995. Consequences of lack of β1 integrin gene expression in mice. Genes Dev. 9:1895-1908.
7. Fässler, R., M. Pfaff, J. Murphy, A. A. Noegel, S. Johansson, R. Timpl, and R. Albrecht. 1995. Lack of β1 integrin gene in embryonic stem cells affects morphology, adhesion, and migration but not integration into the inner cell mass of blastocysts. J. Cell Biol. 128:979-988.
8. Fischer, U., Q. Liu, and G. Dreyfuss. 1997. The SMN-SIP1 complex has an essential role in spliceosomal snRNP biogenesis. Cell. 90:1023-1029.
9. Fischer, U., V. Sumpter, M. Sekine, T. Satoh, and R. Lührmann. 1993. Nucleocytoplasmic transport of U snRNPs: definition of a nuclear location signal in the Sm core domain that binds a transport receptor independently of the m3G cap. EMBO J. 12:573-583.
10. Fischer, U., W. M. Michael, R. Lührmann, and G. Dreyfuss. 1996. Signal mediated nuclear export pathways of proteins and RNAs. Trends Cell Biol. 6:290-293.
11. Fury, M. G., and G. W. Zieve. 1996. U6 snRNA maturation and stability. Exp. Cell Res. 228:160-163.
12. Gottschalk, A., G. Neubauer, J. Banroques, M. Mann, R. Luhrmann, and P. Fabrizio. 1999. Identification by mass spectrometry and functional analysis of novel proteins of the yeast [U4/U6.U5] tri-snRNP. EMBO J. 18:4535-4548.
13. Green, M. J. 1991. Biochemical mechanism of constitutive and regulated pre-mRNA splicing. Annu. Rev. Cell Biol. 7:559-599.
14. Hermann, H., P. Fabrizio, V. A. Raker, K. Foulaki, H. Hornig, H. Brahms, and R. Lührmann. 1995. snRNP Sm proteins share two evolutionarily conserved sequence motifs which are involved in Sm protein-protein interaction. EMBO J. 14:2076-2088.
15. Kambach, C., S. Walke, R. Young, J. M. Avis, E. de la Fortelle, V. A. Raker, R. Luhrmann, J. Li, and K. Nagai. 1999. Crystal structures of two Sm protein complexes and their implications for the assembly of the spliceosomal snRNPs. Cell 96:375-387.
16. Kiledjian, M., and G. Dreyfuss. 1992. Primary structure and binding activity of the hnRNP U protein: binding RNA through RGG box. EMBO J. 11: 2655-2664.
17. Krämer, A. 1996. The structure and function of proteins involved in mammalian pre-mRNA splicing. Annu. Rev. Biochem. 65:367-409.
18. Mattaj, I. W., D. Tollervey, and B. Seraphin. 1993. Small nuclear RNAs in messenger RNA and ribosomal RNA processing. FASEB J. 7:47-53.
19. Mayes, A. E., L. Verdone, P. Legrain, and J. D. Beggs. 1999. Characterization of Sm-like proteins in yeast and their association with U6 snRNA. EMBO J. 18:4321-4331.
20. Nayler, O., C. Cap, and S. Stamm. 1998. Human transformer-2-beta gene: complete nucleotide sequence, chromosomal localisation and generation of a tissue specific isoform. Genomics 53:191-202.
21. Pannone, B. K., D. Xue, and S. L. Wolin. 1998. A role for the yeast La protein in U6 snRNP assembly: evidence that the La protein is a molecular chaperone for RNA polymerase III transcripts. EMBO J. 17:7442-7453.
22. Rio, D. C. 1993. Splicing of pre-mRNA: mechanism, regulation and role in development. Curr. Opin. Genet. Dev. 3:574-584.
23. Salgado-Garrido, J., E. Bragado-Nilsson, S. Kandels-Lewis, and B. Seraphin. 1999. Sm and Sm-like proteins assemble in two related complexes of deep evolutionary origin. EMBO J. 18:3451-3462.
24. Schrank, B., R. Götz, J. M. Gunnersen, J. M. Ure, K. V. Toyka, A. G. Smith, and M. Sendtner. 1997. Inactivation of the survival motor neuron gene, a candidate gene for human spinal muscular atrophy, leads to massive cell death in early mouse embryos. Proc. Natl. Acad. Sci. USA 94:9920-9925.
25. Seraphin, B. 1995. Sm and Sm like proteins belong to a large family: Identification of proteins of the U6 as well as the U1, U2, U4 and U5 snRNPs. EMBO J. 14:2089-2098.
26. Tan, E. M. 1989. Antinuclear antibodies: diagnostic markers for autoimmune diseases and probes for cell biology. Adv. Immunol. 44:93-151.
27. Thompson, J. D., D. G. Higgins, and T. J. Gibson. 1994. CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice. Nucleic Acids Res. 22:4673-4680.