Prevention of mutant SOD1 motoneuron degeneration by copper chelators in vitro

Journal of Neurobiology

Volumn 42, Issue 1, 2000, Pages 49-55

  Azzouz, Mimoun ^a,c   Poindron, Philippe ^a   Guettier, Severine ^a   Leclerc, Nathalie ^a   Andres, Christian ^a   Warter, Jean Marie ^b   Borg, Jacques ^a  

^a UNIVERSITÉ DE STRASBOURG   (France)

^b UNIVERSITY HOSPITAL OF STRASBOURG   (France)

^c Gene Therapy Center   (Switzerland)

Author keywords

Copper chelators; Familial amyotrophic lateral sclerosis; Motoneuron culture; Neurodegenerative disease; SOD1 transgenic mice

Indexed keywords

2,9 DIMETHYL 1,10 PHENANTHROLINE; CHELATING AGENT; COPPER; COPPER ZINC SUPEROXIDE DISMUTASE; DIETHYLDITHIOCARBAMIC ACID;

AMYOTROPHIC LATERAL SCLEROSIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CHELATION; CONTROLLED STUDY; COPPER METABOLISM; EMBRYO; MOUSE; NERVE CELL DEGENERATION; NERVE FIBER GROWTH; NEUROPROTECTION; NEUROTOXICITY; NONHUMAN; PRIORITY JOURNAL; SPINAL CORD MOTONEURON; TRANSGENIC MOUSE;

AMYOTROPHIC LATERAL SCLEROSIS; ANIMALS; BRAIN-DERIVED NEUROTROPHIC FACTOR; CELLS, CULTURED; CHELATING AGENTS; DITIOCARB; MICE; MICE, TRANSGENIC; MOTOR NEURONS; NEURITES; SPINAL CORD; SUPEROXIDE DISMUTASE;

EID: 0033970574     PISSN: 00223034     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-4695(200001)42:1<49::AID-NEU5>3.0.CO;2-7     Document Type: Article

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