The effects of a sub-anaesthetic dose of ketamine on human selective attention

Neuropsychopharmacology

Volumn 22, Issue 3, 2000, Pages 293-302

  Oranje, B ^a   Van Berckel, B N M ^a   Kemner, C ^a   Van Ree, J M ^b   Kahn, R S ^a   Verbaten, M N ^a,b  

^a UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

^b UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

Author keywords

Ketamine; Mismatch negativity; NMDA; P300; Processing negativity; Schizophrenia; Selective attention

Indexed keywords

KETAMINE; N METHYL DEXTRO ASPARTIC ACID RECEPTOR BLOCKING AGENT;

ANESTHESIA; ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DOSE RESPONSE; DOUBLE BLIND PROCEDURE; DRUG EFFECT; ELECTROENCEPHALOGRAM; HUMAN; MALE; MOTOR PERFORMANCE; NORMAL HUMAN; PRIORITY JOURNAL; PSYCHOPHYSIOLOGY; RANDOMIZED CONTROLLED TRIAL; SCHIZOPHRENIA; SELECTIVE ATTENTION; STIMULUS RESPONSE;

ADULT; ATTENTION; DOSE-RESPONSE RELATIONSHIP, DRUG; DOUBLE-BLIND METHOD; ELECTROENCEPHALOGRAPHY; ELECTROOCULOGRAPHY; EXCITATORY AMINO ACID ANTAGONISTS; HUMANS; KETAMINE; MALE; PLACEBOS; REFERENCE VALUES;

EID: 0033965803     PISSN: 0893133X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0893-133X(99)00118-9     Document Type: Article

References (44)

1. Adler C.M., Goldberg T.E., Malhotra A.K., Pickar D., Breier A. Effects of ketamine on thought disorder, working memory, and semantic memory in healthy volunteers. Biol Psychiatry. 43:1998;811-816.
2. Andreasen N.C., Flaum M., Arndt S. The comprehensive assessment of symptoms and history (CASH). An instrument for assessing psychopathology and diagnosis Arch Gen Psychiatry. 49:1992;615-623.
3. Baribeau-Braun J., Picton T.W., Gosselin J.Y. Schizophrenia. A neurophysiological evaluation of abnormal information processing Science. 219:1983;874-876.
4. Boutros N., Nasrallah H., Leighty R., Torello M. Auditory evoked potentials, clinical vs. research applications. Psychiatry Res. 69:1997;183-195.
5. Catts S.V., Shelley A.M., Ward P.B., Liebert B., Mcconaghy N., Andrews S., Michie P.T. Brain potential evidence for an auditory sensory memory deficit in schizophrenia. Am J Psychiatry. 152:1995;213-219.
6. Domino E.F., Chodoff P., Corrsen G. Pharmacologic effects of CI-581, a new dissociative anesthetic, in man. Clin Pharmacol Therap. 6:1965;279-291.
7. Ellison G. The N-methyl-D-aspartate antagonists phencyclidine, ketamine and dizocilpine as both behavioral and anatomical models of the dementias. Brain Res Rev. 20:1995;250-267.
8. Endicott J., Spitzer R.L. A diagnostic interview. The schedule for affective disorders and schizophrenia Arch Gen Psychiatry. 35:1978;837-844.
9. Friedman D. Endogenous scalp-recorded brain potentials in schizophrenia. A methodological review Steinhauer S.R., Gruzelier J.H., Zubin J. Neuropsychology, Psychophysiology, and Information Processing. 1991;91-127 The Netherlands, Elsevier Science Publishing Co, Amsterdam.
10. Grotta J., Clark W., Coull B., Pettigrew L.C., Mackay B., Goldstein L.B., Meissner I., Murphy D., LaRue L. Safety and tolerability of the glutamate antagonist CGS 19755 (Selfotel) in patients with acute ischemic stroke. Results of a phase IIa randomized trial. Stroke. 26:1995;602-605.
11. Javitt D.C., Doneshka P., Zylberman I., Ritter W., Vaughan H.G. Impairment of early cortical processing in schizophrenia. An event-related potential confirmation study Biol Psychiatry. 33:1993;513-519.
12. Javitt D.C., Doneshka P., Grochowski S., Ritter W. Impaired mismatch negativity generation reflects widespread dysfunction of working memory in schizophrenia. Arch Gen Psychiatry. 52:1995;550-558.
13. Javitt D.C., Steinschneider M., Schroeder C.E., Arezzo J.C. Role of cortical N-methyl-D-aspartate receptors in auditory sensory memory and mismatch negativity generation. Implications for schizophrenia Proc Natl Acad Sci USA. 93:1996;11962-11967.
14. Jonkman L.M., Kemner C., Verbaten M.N., Koelega H.S., Camfferman G., van der Gaag R., Buitelaar J.K., van Engeland H. Event-related potentials and performance of Attention-Deficit Hyperactivity Disorder. Children and normal controls in auditory and visual selective attention tasks Biol Psychiatry. 41:1997;595-611.
15. Juckel G., Mullerschubert A., Gaebel W., Hegerl U. Residual symptoms and P300 in schizophrenic outpatients. Psychiatry Res. 65:1996;23-32.
16. Kenemans J.L., Molenaar P.C., Verbaten M.N., Slangen J.L. Removal of the ocular artifact from the EEG. A comparison of time and frequency domain methods with simulated and real data Psychophysiology. 28:1991;114-121.
17. Krystal J.H., Karper L.P., Seibyl J.P., Freeman G.K., Delaney R., Bremner J.D., Heninger G.R., Bowers M.B. Jr., Charney D.S. Subanesthetic effects of the noncompetitive NMDA antagonist, ketamine, in humans. Psychotomimetic, perceptual, cognitive, and neuroendocrine responses. Arch Gen Psychiatry. 51:1994;199-214.
18. Krystal J.H., Karper L.P., Bennett A., D'Souza D.C., Abi Dargham A., Morrissey K., Abi Saab D., Bremner J.D., Bowers M.B. Jr., Suckow R.F., Stetson P., Heninger G.R., Charney D.S. Interactive effects of subanesthetic ketamine and subhypnotic lorazepam in humans. Psychopharmacology. 135:1998;213-229.
19. Lahti A.C., Koffel B., LaPorte D., Tamminga C.A. Subanesthetic doses of ketamine stimulate psychosis in schizophrenia. Neuropsychopharmacology. 13:1995;9-19.
20. LaPorte D.J., Lahti A.C., Koffel B., Tamminga C.A. Absence of ketamine effects on memory and other cognitive functions in schizophrenia patients. J Psychiatric Res. 30:1996;321-330.
21. Luby E.D., Gottlieb J.S., Cohen B.D., Rosenbaum G., Domino E.F. Model psychoses and schizophrenia. Ame J Psychiatry. 119:1962;61-67.
22. Malhotra A.K., Pinals D.A., Weingartner H., Sirocco K. NMDA receptor function and human cognition. The effects of ketamine in healthy volunteers Neuropsychopharmacology. 14:1996;301-307.
23. Malhotra A.K., Pinals D.A., Adler C.M., Elman I., Clifton A., Pickar D., Breier A. Ketamine-induced exacerbation of psychotic symptoms and cognitive impairment in neuroleptic-free schizophrenics. Neuropsychopharmacology. 17:1997;141-150.
24. McGhie A., Chapman J. Disorders of attention and perception in early schizophrenia. Br J Med Psychol. 34:1961;103-116.
25. Näätänen R. Orienting and evoked potentials. Kimmel H.D., Olst E.H., Orlebeke J.F. The Orienting Reflex in Humans. 1979;61-75 Hillsdale, NJ, Erlbaum.
26. Näätänen R. The role of attention in auditory information processing as revealed by event-related potentials and other brain measures of cognitive function. Behav Brain Sci. 13:1990;201-288.
27. Näätänen R., Paavilainen P., Tiitinen H., Jiang D., Alho K. Attention and mismatch negativity. Psychophysiology. 30:1993;436-450.
28. Näätänen R., Picton T.W. The N1 wave of the human electric and magnetic response to sound. A review and an analysis of the component structure Psychophysiology. 24:1987;375-425.
29. Newcomer J.W., Farber N.B., Jevtovic Todorovic V., Selke G., Melson A.K., Hershey T., Craft S., Olney J.W. Ketamine-induced NMDA receptor hypofunction as a model of memory impairment and psychosis. Neuropsychopharmacology. 20:1999;106-118.
30. Oades R.D., Dittmann Balcar A., Zerbin D., Grzella I. Impaired attention-dependent augmentation of MMN in nonparanoid vs. paranoid schizophrenic patients. A comparison with obsessive-compulsive disorder and healthy subjects Biol Psychiatry. 41:1997;1196-1210.
31. Öhman A. The orienting response, attention, and learning. An information-processing perspective Kimmel H.D., Olst E.H., Orlebeke J.F. The Orienting Reflex in Humans. 1979;443-471 Hillsdale, NJ, Erlbaum.
32. Pritchard W.S. Cognitive event-related potential correlates of schizophrenia. Psychol Bull. 100:1986;43-66.
33. Sams M., Paavilainen P., Alho K., Näätänen R. Auditory frequency discrimination and event-related potentials. Electroencephal Clin Neurophysiol Evoked Potentials. 62:1985;437-448.
34. Shelley A.M., Ward P.B., Catts S.V., Mitchie P.T., Andrews S., Mcconaghy N. Mismatch negativity. An index of a preattentive processing deficit in schizophrenia Biol Psychiatry. 30:1991;1059-1062.
35. Strik W.K., Dierks T., Kulke H., Maurer K., Fallgatter A. The predictive value of P300-amplitudes in the course of schizophrenic disorders. J Neural Transm. 103:1996;1351-1359.
36. Toru M., Watanabe S., Shibuya H., Nishikawa T., Noda K., Mitsushio H., Ichikawa H., Kurumaji A., Takashima M., Mataga N., Ogawa A. Neurotransmitters, receptors and neuropeptides in post-mortem brains of chronic schizophrenic patients. Acta Psychiatr Scand. 78:1988;121-137.
37. Tsai G., Passani L.A., Slusher B.S., Carter R., Baer L., Kleinman J.E., Coyle J.T. Abnormal excitatory neurotransmitter metabolism in schizophrenic brains. Arch Gen Psychiatry. 52:1995;829-836.
38. van Berckel B.N.M., Hijman R., van der Linden J.A., Westenberg H.G., van Ree J.M., Kahn R.S. Efficacy and tolerance of D-cycloserine in drug-free schizophrenic patients. Biol Psychiatry. 40:1996;1298-1300.
39. van Berckel B.N.M., Oranje B., Ree J., Mv Verbaten M.N., Kahn R.S. The effects of low dose ketamine on sensory gating, neuroendocrine secretion and behavior in healthy human subjects. Psychopharmacology. 137:1998;271-281.
40. Venables P.H. Overview of psychophysiology in relation to psychopathology with special reference to schizophrenia. Steinhauer S.R., Gruzelier J.H., Zubin J. Neuropsychology, Psychophysiology, and Information Processing. 1991;3-37 The Netherlands, Elsevier Science Publishing Co, Amsterdam.
41. Verbaten M.N., van Engeland H. Neuro)physiologic similarities between childhood developmental disorders and schizophrenia. Den Boer J.A., Westenberg H.G.M., Van Praag H.M. Advances in the Neurobiology of Schizophrenia. 1995;369-400 New York, Brisbane, Toronto, Singapore, Wiley & Sons Ltd, Chichester.
42. Ward P.B., Catts S.V., Fox A.M., Michie P.T., Mcconaghy N. Auditory selective attention and event-related potentials in schizophrenia. Br J Psychiatry. 158:1991;534-539.
43. Woldorff M.G., Hackley S.A., Hillyard S.A. The effects of channel-selective attention on the mismatch negativity wave elicited by deviant tones. Psychophysiology. 28:1991;30-42.
44. Woldorff M.G., Hillyard S.A. Modulation of early auditory processing during selective listening to rapidly presented tones. Electroencephal Clin Neurophysiol. 79:1991;170-191.