메뉴 건너뛰기




Volumn 30, Issue 2, 2000, Pages 458-469

The BOB.1/OBF.1 co-activator is essential for octamer-dependent transcription in B cells

Author keywords

B cell specific gene expression; BOB.1 OBF.1 co activator; Conditional gene regulation; Oct1 Oct2 transcription factor; Octamer dependent transcription

Indexed keywords

CELL PROTEIN; TRANSCRIPTION FACTOR;

EID: 0033963959     PISSN: 00142980     EISSN: None     Source Type: Journal    
DOI: 10.1002/1521-4141(200002)30:2<458::AID-IMMU458>3.0.CO;2-5     Document Type: Article
Times cited : (48)

References (58)
  • 1
    • 0025817426 scopus 로고
    • Immunoglobulin gene transcription
    • Staudt, L. M. and Lenardo, M. J., Immunoglobulin gene transcription. Annu. Rev. Immunol. 1991. 9: 373-398.
    • (1991) Annu. Rev. Immunol. , vol.9 , pp. 373-398
    • Staudt, L.M.1    Lenardo, M.J.2
  • 2
    • 0009568383 scopus 로고
    • Transcriptional regulation of immunoglobulin gene expression
    • Cohen, P. and Foulkes, J. G. (Eds.) Elsevier-Biomedical. Amsterdam
    • Libermann, T. A. and Baltimore, D., Transcriptional regulation of immunoglobulin gene expression. In Cohen, P. and Foulkes, J. G. (Eds.) The hormonal control of gene transcription. Elsevier-Biomedical. Amsterdam 1991, pp 385-407.
    • (1991) The Hormonal Control of Gene Transcription , pp. 385-407
    • Libermann, T.A.1    Baltimore, D.2
  • 3
    • 0024519494 scopus 로고
    • How do different transcription factors binding the same DNA sequence sort out their jobs?
    • Schaffner, W., How do different transcription factors binding the same DNA sequence sort out their jobs? Trends Genet. 1989. 5: 37-39.
    • (1989) Trends Genet. , vol.5 , pp. 37-39
    • Schaffner, W.1
  • 5
    • 0025886340 scopus 로고
    • Octamania: The POU factors in murine development
    • Schöler, H. R., Octamania: The POU factors in murine development. Trends Genet. 1991. 7: 323-329.
    • (1991) Trends Genet. , vol.7 , pp. 323-329
    • Schöler, H.R.1
  • 6
    • 0028321392 scopus 로고
    • The POU domains of the Oct1 and Oct2 transcription factors mediate specific interaction with TBP
    • Zwilling, S., Annweiler, A. and Wirth, T., The POU domains of the Oct1 and Oct2 transcription factors mediate specific interaction with TBP. Nucleic Acids Res. 1994. 22: 1655-1662.
    • (1994) Nucleic Acids Res. , vol.22 , pp. 1655-1662
    • Zwilling, S.1    Annweiler, A.2    Wirth, T.3
  • 7
    • 0028921810 scopus 로고
    • HMG2 functionally interacts with the POU domains of octamer transcription factors
    • Zwilling, S., König, H. and Wirth, T., HMG2 functionally interacts with the POU domains of octamer transcription factors. EMBO J. 1995. 14: 1198-1208.
    • (1995) EMBO J. , vol.14 , pp. 1198-1208
    • Zwilling, S.1    König, H.2    Wirth, T.3
  • 8
    • 0025220995 scopus 로고
    • Activation of octamer-containing promoters by either octamer-binding transcription factor 1 (OTF-1) or OTF-2 and requirement of an additional B-cell-specific component for optimal transcription of immunoglobulin promoters
    • Pierani, A., Heguy, A., Fujii, H. and Roeder, R. G., Activation of octamer-containing promoters by either octamer-binding transcription factor 1 (OTF-1) or OTF-2 and requirement of an additional B-cell-specific component for optimal transcription of immunoglobulin promoters. Mol. Cell. Biol. 1990. 10: 6204-6215.
    • (1990) Mol. Cell. Biol. , vol.10 , pp. 6204-6215
    • Pierani, A.1    Heguy, A.2    Fujii, H.3    Roeder, R.G.4
  • 9
    • 0026693624 scopus 로고
    • A novel B cell-derived coactivator potentiates the activation of immunoglobulin by octamer-binding transcription factors
    • Luo, Y., Fujii, H., Gerster, T. and Roeder, R. G., A novel B cell-derived coactivator potentiates the activation of immunoglobulin by octamer-binding transcription factors. Cell 1992. 71: 231-241.
    • (1992) Cell , vol.71 , pp. 231-241
    • Luo, Y.1    Fujii, H.2    Gerster, T.3    Roeder, R.G.4
  • 10
  • 11
    • 0028350872 scopus 로고
    • Differential transactivation potential of Oct1 and Oct2 is determined by additional B cell-specific activities
    • Pfisterer, P., Annweiler, A., Ullmer, C., Corcoran, L. and Wirth, T., Differential transactivation potential of Oct1 and Oct2 is determined by additional B cell-specific activities. EMBO J. 1994. 13: 1654-1663.
    • (1994) EMBO J. , vol.13 , pp. 1654-1663
    • Pfisterer, P.1    Annweiler, A.2    Ullmer, C.3    Corcoran, L.4    Wirth, T.5
  • 12
    • 0026689268 scopus 로고
    • Oct2 transactivation from a remote enhancer position requires a B-cell-restricted activity
    • Annweiler, A., Müller-Immerglück, M. and Wirth, T., Oct2 transactivation from a remote enhancer position requires a B-cell-restricted activity. Mol. Cell. Biol. 1992. 12: 3107-3116.
    • (1992) Mol. Cell. Biol. , vol.12 , pp. 3107-3116
    • Annweiler, A.1    Müller-Immerglück, M.2    Wirth, T.3
  • 13
    • 0028854837 scopus 로고
    • A B-cell coactivator of octamer-binding transcription factors
    • Gstaiger, M., Knoepfel, L., Georgiev, O., Schaffner, W. and Hovens, C. M., A B-cell coactivator of octamer-binding transcription factors. Nature 1995. 373: 360-362.
    • (1995) Nature , vol.373 , pp. 360-362
    • Gstaiger, M.1    Knoepfel, L.2    Georgiev, O.3    Schaffner, W.4    Hovens, C.M.5
  • 14
    • 0028842156 scopus 로고
    • OBF-1, a novel B cell-specific coactivator that stimulates immunoglobulin promoter activity through association with octamer proteins
    • Strubin, M., Newell, J. W. and Matthias, P., OBF-1, a novel B cell-specific coactivator that stimulates immunoglobulin promoter activity through association with octamer proteins. Cell 1995. 80: 497-506.
    • (1995) Cell , vol.80 , pp. 497-506
    • Strubin, M.1    Newell, J.W.2    Matthias, P.3
  • 15
    • 0029041509 scopus 로고
    • Cloning, functional characterization, and mechanism of action of the B-cell-specific transcriptional coactivator OCA-B
    • Luo, Y. and Roeder, R. G., Cloning, functional characterization, and mechanism of action of the B-cell-specific transcriptional coactivator OCA-B. Mol. Cell. Biol. 1995. 15: 4115-4124.
    • (1995) Mol. Cell. Biol. , vol.15 , pp. 4115-4124
    • Luo, Y.1    Roeder, R.G.2
  • 16
    • 0029562217 scopus 로고
    • Functional characterization of the murine homolog of the B-cell-specific coactivator BOB.1/OBF.1
    • Pfisterer, P., Zwilling, S., Hess, J. and Wirth, T., Functional characterization of the murine homolog of the B-cell-specific coactivator BOB.1/OBF.1. J. Biol. Chem. 1995. 270: 29870-29880.
    • (1995) J. Biol. Chem. , vol.270 , pp. 29870-29880
    • Pfisterer, P.1    Zwilling, S.2    Hess, J.3    Wirth, T.4
  • 17
    • 0030710206 scopus 로고    scopus 로고
    • Using altered specificity Oct-1 and Oct-2 mutants to analyze the regulation of immunoglobulin gene transcription
    • Shah, P. C., Bertolino, E. and Singh, H., Using altered specificity Oct-1 and Oct-2 mutants to analyze the regulation of immunoglobulin gene transcription. EMBO J. 1997. 16: 7105-7117.
    • (1997) EMBO J. , vol.16 , pp. 7105-7117
    • Shah, P.C.1    Bertolino, E.2    Singh, H.3
  • 18
    • 0029935909 scopus 로고    scopus 로고
    • The B cell coactivator Bob1 shows DNA sequence-dependent complex formation with the Oct-1/Oct-2 factors, leading to differential promoter activation
    • Gstaiger, M., Georgiev, O., van Leeuwen, H., van der Vliet, P. and Schaffner, W., The B cell coactivator Bob1 shows DNA sequence-dependent complex formation with the Oct-1/Oct-2 factors, leading to differential promoter activation. EMBO J. 1996. 15: 2781-2790.
    • (1996) EMBO J. , vol.15 , pp. 2781-2790
    • Gstaiger, M.1    Georgiev, O.2    Van Leeuwen, H.3    Van Der Vliet, P.4    Schaffner, W.5
  • 19
    • 0029967014 scopus 로고    scopus 로고
    • Sequence-specific DNA binding of the B-cell-specific coactivator OCA-B
    • Cepek, K. L., Chasman, D. I. and Sharp, P. A., Sequence-specific DNA binding of the B-cell-specific coactivator OCA-B. Genes Dev. 1996. 10: 2079-2088.
    • (1996) Genes Dev. , vol.10 , pp. 2079-2088
    • Cepek, K.L.1    Chasman, D.I.2    Sharp, P.A.3
  • 20
    • 0030679566 scopus 로고    scopus 로고
    • OCA-B is a functional analog of VP16 but targets a separate surface of the Oct-1 POU domain
    • Babb, R., Cleary, M. A. and Herr, W., OCA-B is a functional analog of VP16 but targets a separate surface of the Oct-1 POU domain. Mol. Cell. Biol. 1997. 17: 7295-7305.
    • (1997) Mol. Cell. Biol. , vol.17 , pp. 7295-7305
    • Babb, R.1    Cleary, M.A.2    Herr, W.3
  • 21
    • 0031784025 scopus 로고    scopus 로고
    • Coactivator OBF-1 makes selective contacts with both the POU-specific domain and the POU homeodomain and acts as a molecular clamp on DNA
    • Sauter, P. and Matthias, P., Coactivator OBF-1 makes selective contacts with both the POU-specific domain and the POU homeodomain and acts as a molecular clamp on DNA. Mol. Cell. Biol. 1998. 18: 7397-7409.
    • (1998) Mol. Cell. Biol. , vol.18 , pp. 7397-7409
    • Sauter, P.1    Matthias, P.2
  • 22
    • 0030816433 scopus 로고    scopus 로고
    • Inducible expression and phosphorylation of coactivator BOB.1/OBF.1 in T cells
    • Zwilling, S., Dieckmann, A., Pfisterer, P., Angel, P. and Wirth, T., Inducible expression and phosphorylation of coactivator BOB.1/OBF.1 in T cells. Science 1997. 277: 221-225.
    • (1997) Science , vol.277 , pp. 221-225
    • Zwilling, S.1    Dieckmann, A.2    Pfisterer, P.3    Angel, P.4    Wirth, T.5
  • 23
    • 0030014708 scopus 로고    scopus 로고
    • Gene structure and characterization of the murine homologue of the B cell-specific transcriptional coactivator OBF-1
    • Schubart, D. B., Sauter, P., Massa, S., Friedl, E. M., Schwarzenbach, H. and Matthias, P., Gene structure and characterization of the murine homologue of the B cell-specific transcriptional coactivator OBF-1. Nucleic Acids Res. 1996. 24: 1913-1920.
    • (1996) Nucleic Acids Res. , vol.24 , pp. 1913-1920
    • Schubart, D.B.1    Sauter, P.2    Massa, S.3    Friedl, E.M.4    Schwarzenbach, H.5    Matthias, P.6
  • 24
    • 0031835435 scopus 로고    scopus 로고
    • Coactivation by OCA-B: Definition of critical regions and synergism with general cofactors
    • Luo, Y., Ge, H., Stevens, S., Xiao, H. and Roeder, R. G., Coactivation by OCA-B: definition of critical regions and synergism with general cofactors. Mol. Cell. Biol. 1998. 18: 3803-3810.
    • (1998) Mol. Cell. Biol. , vol.18 , pp. 3803-3810
    • Luo, Y.1    Ge, H.2    Stevens, S.3    Xiao, H.4    Roeder, R.G.5
  • 25
    • 0029993971 scopus 로고    scopus 로고
    • Coordinate suppression of myeloma-specific genes in myeloma x fibroblast somatic hybrids
    • Reich, L., Sharir, H., Ber, R., Wirth, T., Bergman, Y. and Laskov, R., Coordinate suppression of myeloma-specific genes in myeloma x fibroblast somatic hybrids. Somat. Cell Mol. Genet. 1996. 22: 1-20.
    • (1996) Somat. Cell Mol. Genet. , vol.22 , pp. 1-20
    • Reich, L.1    Sharir, H.2    Ber, R.3    Wirth, T.4    Bergman, Y.5    Laskov, R.6
  • 26
    • 0032168362 scopus 로고    scopus 로고
    • OCA-B integrates B cell antigen receptor-, CD40L- And IL 4-mediated signals for the germinal center pathway of B cell development
    • Qin, X. F., Reichlin, A., Luo, Y., Roeder, R. G. and Nussenzweig, M. C., OCA-B integrates B cell antigen receptor-, CD40L- and IL 4-mediated signals for the germinal center pathway of B cell development. EMBO J. 1998. 17 5066-5075.
    • (1998) EMBO J. , vol.17 , pp. 5066-5075
    • Qin, X.F.1    Reichlin, A.2    Luo, Y.3    Roeder, R.G.4    Nussenzweig, M.C.5
  • 27
    • 0029967024 scopus 로고    scopus 로고
    • B-cell-specific coactivator OBF-1/OCA-B/ Bob1 required for immune response and germinal centre formation
    • Schubart, D. B., Rolink, A., Kosco-Vilbois, M. H., Botteri, F. and Matthias, P., B-cell-specific coactivator OBF-1/OCA-B/ Bob1 required for immune response and germinal centre formation. Nature 1996. 383: 538-542.
    • (1996) Nature , vol.383 , pp. 538-542
    • Schubart, D.B.1    Rolink, A.2    Kosco-Vilbois, M.H.3    Botteri, F.4    Matthias, P.5
  • 28
    • 0029917392 scopus 로고    scopus 로고
    • The B-cell-specific transcription coactivator OCA-B/OBF-1/Bob-1 is essential for normal production of immunoglobulin isotypes
    • Kim, U., Quin, F.-F., Gong, S., Stevens, S., Luo, Y., Nussenzweig, M. and Roeder, R. G., The B-cell-specific transcription coactivator OCA-B/OBF-1/Bob-1 is essential for normal production of immunoglobulin isotypes. Nature 1996. 383: 542-547.
    • (1996) Nature , vol.383 , pp. 542-547
    • Kim, U.1    Quin, F.-F.2    Gong, S.3    Stevens, S.4    Luo, Y.5    Nussenzweig, M.6    Roeder, R.G.7
  • 29
    • 10544228521 scopus 로고    scopus 로고
    • B lymphocytes are impaired in mice lacking the transcriptional coactivator Bob1/OCA-B/OBF1
    • Nielsen, P. J., Georgiev, O., Lorenz, B. and Schaffner, W., B lymphocytes are impaired in mice lacking the transcriptional coactivator Bob1/OCA-B/OBF1. Eur. J. Immunol. 1996. 26: 3214-3218.
    • (1996) Eur. J. Immunol. , vol.26 , pp. 3214-3218
    • Nielsen, P.J.1    Georgiev, O.2    Lorenz, B.3    Schaffner, W.4
  • 30
    • 0030816215 scopus 로고    scopus 로고
    • Efficient transcription of an immunoglobulin kappa promoter requires specific sequence elements overlapping with and down-stream of the transcriptional start site
    • Pelletier, M. R., Hatada, E. N., Scholz, G. and Scheidereit, C., Efficient transcription of an immunoglobulin kappa promoter requires specific sequence elements overlapping with and down-stream of the transcriptional start site. Nucleic Acids Res. 1997. 25: 3995-4003.
    • (1997) Nucleic Acids Res. , vol.25 , pp. 3995-4003
    • Pelletier, M.R.1    Hatada, E.N.2    Scholz, G.3    Scheidereit, C.4
  • 31
    • 0025944311 scopus 로고
    • Regulation and a possible stage-specific function of Oct-2 during pre-B-cell differentiation
    • Miller, C. L., Feldhaus, A. L, Rooney, J. W., Rhodes, L. D., Sibley, C. H. and Singh, H., Regulation and a possible stage-specific function of Oct-2 during pre-B-cell differentiation. Mol. Cell. Biol. 1991. 11: 4885-4894.
    • (1991) Mol. Cell. Biol. , vol.11 , pp. 4885-4894
    • Miller, C.L.1    Feldhaus, A.L.2    Rooney, J.W.3    Rhodes, L.D.4    Sibley, C.H.5    Singh, H.6
  • 32
    • 0021165918 scopus 로고
    • Correct transcription of an immunoglobulin n gene requires an upstream fragment containing conserved sequence elements
    • Falkner, F. G. and Zachau, H. G., Correct transcription of an immunoglobulin n gene requires an upstream fragment containing conserved sequence elements. Nature 1984. 310: 71-74.
    • (1984) Nature , vol.310 , pp. 71-74
    • Falkner, F.G.1    Zachau, H.G.2
  • 33
    • 1542735785 scopus 로고
    • Two regulatory elements for immunoglobulin n light chain gene expression
    • Bergman, Y., Rice, D., Grosschedl, R. and Baltimore, D., Two regulatory elements for immunoglobulin n light chain gene expression. Proc. Natl. Acad. Sci. USA 1984. 81: 7041-7045.
    • (1984) Proc. Natl. Acad. Sci. USA , vol.81 , pp. 7041-7045
    • Bergman, Y.1    Rice, D.2    Grosschedl, R.3    Baltimore, D.4
  • 34
    • 0023195439 scopus 로고
    • An octamer oligonucleotide upstream of a TATa motif is sufficient for lymphoid-specific promoter activity
    • Wirth, T., Staudt, L. and Baltimore, A., An octamer oligonucleotide upstream of a TATA motif is sufficient for lymphoid-specific promoter activity. Nature 1987. 329: 174-178.
    • (1987) Nature , vol.329 , pp. 174-178
    • Wirth, T.1    Staudt, L.2    Baltimore, A.3
  • 35
    • 0023280348 scopus 로고
    • Protein-binding sites in Ig gene enhancers determine transcriptional acitivity and inducibility
    • Lenardo, M., Pierce, J. W. and Baltimore, D., Protein-binding sites in Ig gene enhancers determine transcriptional acitivity and inducibility. Science 1987. 236: 1573-1577.
    • (1987) Science , vol.236 , pp. 1573-1577
    • Lenardo, M.1    Pierce, J.W.2    Baltimore, D.3
  • 36
    • 0025806272 scopus 로고
    • Complex pattern of immunoglobulin μ gene expression in normal and transgenic mice: Non-overlapping regulatory sequences govern distinct tissue specificities
    • Jenuwein, T. and Grosschedl, R., Complex pattern of immunoglobulin μ gene expression in normal and transgenic mice: non-overlapping regulatory sequences govern distinct tissue specificities. Genes Dev. 1991. 5: 932-943.
    • (1991) Genes Dev. , vol.5 , pp. 932-943
    • Jenuwein, T.1    Grosschedl, R.2
  • 37
    • 0026507843 scopus 로고
    • Functional analysis of defined mutations in the immunoglobulin heavy-chain enhancer in transgenic mice
    • Annweiler, A., Müller, U. and Wirth, T., Functional analysis of defined mutations in the immunoglobulin heavy-chain enhancer in transgenic mice. Nucleic Acids Res. 1992. 20: 1503-1509.
    • (1992) Nucleic Acids Res. , vol.20 , pp. 1503-1509
    • Annweiler, A.1    Müller, U.2    Wirth, T.3
  • 38
    • 0027939216 scopus 로고
    • Functional differences between the Oct2 transactivation domains determine the trans-activation potential of individual Oct2 isoforms
    • Annweiler, A., Zwilling, S. and Wirth, T., Functional differences between the Oct2 transactivation domains determine the trans-activation potential of individual Oct2 isoforms. Nucleic Acids Res. 1994. 22: 4250-4258.
    • (1994) Nucleic Acids Res. , vol.22 , pp. 4250-4258
    • Annweiler, A.1    Zwilling, S.2    Wirth, T.3
  • 39
    • 0026315351 scopus 로고
    • Activation of early gene expression in T lymphocytes by Oct-1 and an inducible protein, OAP40
    • Ullman, K. S., Flanagan, W. M., Edwards, C. A. and Crabtree, G. R., Activation of early gene expression in T lymphocytes by Oct-1 and an inducible protein, OAP40. Science 1991. 254: 558-562.
    • (1991) Science , vol.254 , pp. 558-562
    • Ullman, K.S.1    Flanagan, W.M.2    Edwards, C.A.3    Crabtree, G.R.4
  • 41
  • 42
    • 0032146036 scopus 로고    scopus 로고
    • Th2-specific protein/DNA interactions at the proximal Nuclear Factor-at site contribute to the functional activity of the human IL-4 promoter
    • Li-Weber, M., Salgame, P., Hu, C., Davydov, I. V., Laur, O., Klevens, S. and Krammer, P. H., Th2-specific protein/DNA interactions at the proximal Nuclear Factor-AT site contribute to the functional activity of the human IL-4 promoter. J. Immunol. 1998. 161: 1380-1389.
    • (1998) J. Immunol. , vol.161 , pp. 1380-1389
    • Li-Weber, M.1    Salgame, P.2    Hu, C.3    Davydov, I.V.4    Laur, O.5    Klevens, S.6    Krammer, P.H.7
  • 43
    • 0031002767 scopus 로고    scopus 로고
    • A T cell-specific enhancer in the interleukin-3 locus is activated cooperatively by Oct and NFAT elements within a DNase I-hypersensitive site
    • Duncliffe, K. N., Bert, A. G., Vadas, M. A. and Cockerill, P., A T cell-specific enhancer in the interleukin-3 locus is activated cooperatively by Oct and NFAT elements within a DNase I-hypersensitive site. Immunity 1997. 6: 175-185.
    • (1997) Immunity , vol.6 , pp. 175-185
    • Duncliffe, K.N.1    Bert, A.G.2    Vadas, M.A.3    Cockerill, P.4
  • 44
    • 0030960672 scopus 로고    scopus 로고
    • Transcriptional activation by recruitment
    • Ptashne, M. and Gann, A., Transcriptional activation by recruitment. Nature 1997. 386: 569-577.
    • (1997) Nature , vol.386 , pp. 569-577
    • Ptashne, M.1    Gann, A.2
  • 45
    • 0032479079 scopus 로고    scopus 로고
    • Going the distance: A current view of enhancer action
    • Blackwood, E. M. and Kadonaga, J. T., Going the distance: a current view of enhancer action. Science 1998. 281: 61-63.
    • (1998) Science , vol.281 , pp. 61-63
    • Blackwood, E.M.1    Kadonaga, J.T.2
  • 46
    • 0025215391 scopus 로고
    • The cell type-specific octamer transcription factor OTF-2 has two domains required for the activation of transcription
    • Gerster, T., Balmaceda, C.-G. and Roeder, R. G., The cell type-specific octamer transcription factor OTF-2 has two domains required for the activation of transcription. EMBO J. 1990. 9: 1635-1643.
    • (1990) EMBO J. , vol.9 , pp. 1635-1643
    • Gerster, T.1    Balmaceda, C.-G.2    Roeder, R.G.3
  • 47
    • 0025250073 scopus 로고
    • Transcription factor Oct-2a contains functionally redundant activating domains and works selectively from a promoter but not from a remote enhancer position in non-lymphoid (HeLa) cells
    • Müller-Immerglück, M. M., Schaffner, W. and Matthias, P., Transcription factor Oct-2A contains functionally redundant activating domains and works selectively from a promoter but not from a remote enhancer position in non-lymphoid (HeLa) cells. EMBO J. 1990. 9: 1625-1634.
    • (1990) EMBO J. , vol.9 , pp. 1625-1634
    • Müller-Immerglück, M.M.1    Schaffner, W.2    Matthias, P.3
  • 48
    • 0027171744 scopus 로고
    • Targeted disruption of the Oct-2 locus in a B cell provides genetic evidence for two distinct cell type-specific pathways of octamer element-mediated gene activation
    • Feldhaus, A. L., Klug, C. A., Arvin, K. L. and Singh, H., Targeted disruption of the Oct-2 locus in a B cell provides genetic evidence for two distinct cell type-specific pathways of octamer element-mediated gene activation. EMBO J. 1993. 12: 2763-2772.
    • (1993) EMBO J. , vol.12 , pp. 2763-2772
    • Feldhaus, A.L.1    Klug, C.A.2    Arvin, K.L.3    Singh, H.4
  • 49
    • 0029002136 scopus 로고
    • A modified oestrogen receptor ligand-binding domain as an improved switch for the regulation of heterologous proteins
    • Littlewood, T. D., Hancock, D. C., Danielian, P. S., Parker, M. G. and Evan, G. I., A modified oestrogen receptor ligand-binding domain as an improved switch for the regulation of heterologous proteins. Nucleic Acids Res. 1995. 23: 1686-1690.
    • (1995) Nucleic Acids Res. , vol.23 , pp. 1686-1690
    • Littlewood, T.D.1    Hancock, D.C.2    Danielian, P.S.3    Parker, M.G.4    Evan, G.I.5
  • 50
    • 0029844184 scopus 로고    scopus 로고
    • Induction of antigen-specific tumor immunity by genetic and cellular vaccines against MAGE: Enhanced tumor protection by coexpression of granulocyte-macrophage colony-stimulating factor and B7-1
    • Bueler, H. and Mulligan, R. C., Induction of antigen-specific tumor immunity by genetic and cellular vaccines against MAGE: enhanced tumor protection by coexpression of granulocyte-macrophage colony-stimulating factor and B7-1. Mol. Med. 1996. 2: 545-555.
    • (1996) Mol. Med. , vol.2 , pp. 545-555
    • Bueler, H.1    Mulligan, R.C.2
  • 51
    • 0025352187 scopus 로고
    • Advanced mammalian gene transfer: High titre retroviral vectors with multiple drug selection markers and a complementary helper-free packaging cell line
    • Morgenstern, J. P. and Land, H., Advanced mammalian gene transfer: high titre retroviral vectors with multiple drug selection markers and a complementary helper-free packaging cell line. Nucleic Acids Res. 1990. 18: 3587-3596.
    • (1990) Nucleic Acids Res. , vol.18 , pp. 3587-3596
    • Morgenstern, J.P.1    Land, H.2
  • 52
    • 0021930325 scopus 로고
    • Cell-type specificity of immunoglobulin gene expression is regulated by at least three DNA sequence elements
    • Grosschedl, R. and Baltimore, D., Cell-type specificity of immunoglobulin gene expression is regulated by at least three DNA sequence elements. Cell 1985. 41: 885-897.
    • (1985) Cell , vol.41 , pp. 885-897
    • Grosschedl, R.1    Baltimore, D.2
  • 53
    • 0027521432 scopus 로고
    • Distinct NF-nB/Rel transcription factors are responsible for tissue-specific and inducible gene activation
    • Lernbecher, T., Müller, U. and Wirth, T., Distinct NF-nB/Rel transcription factors are responsible for tissue-specific and inducible gene activation. Nature 1993. 365: 767-770.
    • (1993) Nature , vol.365 , pp. 767-770
    • Lernbecher, T.1    Müller, U.2    Wirth, T.3
  • 54
    • 0024094754 scopus 로고
    • Nuclear factor NF-nB can interact functionally with its cognate binding site to provide lymphoid-specific promoter function
    • Wirth, T. and Baltimore, D., Nuclear factor NF-nB can interact functionally with its cognate binding site to provide lymphoid-specific promoter function. EMBO J. 1988. 7: 3109-3113.
    • (1988) EMBO J. , vol.7 , pp. 3109-3113
    • Wirth, T.1    Baltimore, D.2
  • 55
    • 0029118199 scopus 로고
    • Identification of CD36 as the first gene dependent on the B cell differentiation factor Oct2
    • König, H., Pfisterer, P., Corcoran, L. and Wirth, T., Identification of CD36 as the first gene dependent on the B cell differentiation factor Oct2. Genes Dev. 1995. 9: 1598-1607.
    • (1995) Genes Dev. , vol.9 , pp. 1598-1607
    • König, H.1    Pfisterer, P.2    Corcoran, L.3    Wirth, T.4
  • 57
    • 0028288515 scopus 로고
    • The heat-stable antigen can alter very late antigen 4-mediated adhesion
    • Hahne, M., Wenger, R. H., Vestweber, D. and Nielsen, P. J., The heat-stable antigen can alter very late antigen 4-mediated adhesion. J. Exp. Med. 1994. 179: 1391-1395.
    • (1994) J. Exp. Med. , vol.179 , pp. 1391-1395
    • Hahne, M.1    Wenger, R.H.2    Vestweber, D.3    Nielsen, P.J.4
  • 58
    • 0029833422 scopus 로고    scopus 로고
    • Episomal vectors rapidly and stably produce high-titer recombinant retrovirus
    • Kinsella, T. M. and Nolan, G. P., Episomal vectors rapidly and stably produce high-titer recombinant retrovirus. Hum. Gene Ther. 1996. 7: 1405-1413.
    • (1996) Hum. Gene Ther. , vol.7 , pp. 1405-1413
    • Kinsella, T.M.1    Nolan, G.P.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.