Changes of the Trans-activating potential of AP-1 transcription factor during cyclosporin A-induced apoptosis of glioma cells are mediated by phosphorylation and alterations of AP-1 composition

Journal of Neurochemistry

Volumn 74, Issue 1, 2000, Pages 42-51

  Pyrzynska, Beata ^a   Mosieniak, Grazyna ^a   Kaminska, Bozena ^a  

^a NENCKI INSTITUTE OF EXPERIMENTAL BIOLOGY   (Poland)

Author keywords

Apoptosis; ATF 2; c Jun N terminal kinase signaling; c Jun proteins; Jun proteins; Transcription factors; Transcription regulation

Indexed keywords

CYCLOSPORIN A; STRESS ACTIVATED PROTEIN KINASE; TRANSCRIPTION FACTOR;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL ACTIVATION; CELL PROLIFERATION; CONTROLLED STUDY; DNA BINDING; DNA DAMAGE; GLIOMA CELL; HUMAN; HUMAN CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN PHOSPHORYLATION; RAT; STRESS;

ANIMALS; APOPTOSIS; CELL DIVISION; CYCLOSPORINE; GLIOMA; HUMANS; JNK MITOGEN-ACTIVATED PROTEIN KINASES; MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHORYLATION; PROMOTER REGIONS (GENETICS); RATS; TRANS-ACTIVATION (GENETICS); TRANSCRIPTION FACTOR AP-1; TUMOR CELLS, CULTURED;

ANIMALIA;

EID: 0033961788     PISSN: 00223042     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1471-4159.2000.0740042.x     Document Type: Article

References (63)

1. Abate C., Luk D., and Curran T. (1991) Transcriptional regulation by Fos and Jun in vitro: interaction among multiple activator and regulatory domains. Mol. Cell. Biol. 11, 3624-3632.
2. Anderson A. J., Su J. H., and Cotman C. W. (1996) DNA damage and apoptosis in Alzheimer's disease: colocalization with c-Jun immunoreactivity, relationship to brain area, and effect of postmortem delay. J. Neurosci. 16, 1710-1719.
3. Angel P. and Karin M. (1991) The role of Jun, Fos and the AP-1 complex in cell proliferation and transformation. Biochim. Biophys. Acta 1072, 129-157.
4. Angel P., Hattori K., Smeal T., and Karin M. (1988) The jun protooncogene is positively autoregulated by its product, Jun/AP-1. Cell 55, 875-885.
5. Ashkenazi A. and Dixit V. M. (1998) Death receptors: signaling and modulation. Science 281, 1305-1308.
6. Benbrook D. M. and Jones N. C. (1990) Heterodimer formation between CREB and JUN proteins. Oncogene 5, 295-302.
7. Bossy-Wetzel E., Bakiri L., and Yaniv M. (1997) Induction of apoptosis by the transcription factor c-Jun. EMBO J. 16, 1695-1709.
8. Bradford M. M. (1976) A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem. 72, 248-254.
9. Chen Y. R., Meyer C. F., and Tan T. H. (1996) Persistent activation of c-Jun N-terminal kinase 1 (JNK1) in gamma radiation-induced apoptosis. J. Biol. Chem. 271, 631-634.
10. Deng T. and Karin M. (1993) JunB differs from c-Jun in its DNA-binding and dimerization domains, and represses c-Jun by formation of inactive heterodimers. Genes Dev. 7, 479-490.
11. Dérijard B., Hibi M., Wu I.-H., Barrett T., Su B., Deng T., Karin M., and Davis R. J. (1994) JNK1: a protein kinase stimulated by UV light and Ha-Ras that binds and phosphorylates the c-Jun activation domain. Cell 76, 1025-1037.
12. Dragunow M. and Preston K. (1995) The role of inducible transcription factors in apoptotic nerve cell death. Brain Res. Brain Res. Rev. 21, 1-28.
13. Dragunow M., Young D., Hughes D., MacGibbon G., Lawlor P., Singleton K., Sirimanne E., Beilharz E., and Glucan P. (1993) Is c-Jun involved in nerve cell death following status epilepticus and hypoxic-ischaemic brain injury? Mol. Brain Res. 18, 347-352.
14. Eilers A., Whitfield J., Babij C., Rubin L. L., and Ham J. (1998) Role of the Jun kinase pathway in the regulation of c-Jun expression and apoptosis in sympathetic neurons. J. Neurosci. 18, 1713-1724.
15. Estus S., Zaks W. J., Freeman R. S., Gruda M., Bravo R., and Johnston E. M. (1994) Altered gene expression in neurons during programmed cell death: identification of c-jun as necessary for neuronal apoptosis. J. Cell Biol. 127, 1717-1727.
16. Faris M., Kokot N., Latinis K., Kasibhatla S., Green D. R., Koretzky G. A., and Nel A. (1998a) The c-Jun N-terminal kinase cascade plays a role in stress-induced apoptosis in Jurkat cells by upregulating Fas ligand expression. J. Immunol. 160, 134-144.
17. Fans M., Latinis K. M., Kempiak S. J., Koretzky G. A., and Nel A. (1998b) Stress-induced Fas ligand expression in T cells is mediated through a MEK kinase 1-regulated response element in the Fas ligand promoter. Mol. Cell Biol 18, 5414-5424.
18. Figiel I. and Kaczmarek L. (1997) Cellular and molecular correlates of glutamate-evoked neuronal programmed cell death in the in vitro cultures of rat hippocampal dentate gyrus. Neurochem. Int. 31, 229-240.
19. Gajate C., Alonso M. T., Schimmang T., and Mollinedo F. (1996) C-Fos is not essential for apoptosis. Biochem. Biophys. Res. Commun. 218, 267-272.
20. Gupta S., Campbell D., Dérijard B., and Davis R. J. (1995) Transcription factor ATF2 regulation by the JNK signal transduction pathway. Science 267, 389-393.
21. Hai T. and Curran T. (1991) Cross-family dimerization of transcription factors Fos/Jun and ATF/CREB alters DNA binding specificity. Proc. Natl. Acad. Sci. USA 88, 3720-3724.
22. Ham J., Babij C., Whiteneld J., Pfarr C. M., Lallemand D., Yaniv M., and Rubin L. L. (1995) A c-Jun dominant negative mutant protects sympathetic neurons against programmed cell death. Neuron 14, 927-939.
23. Herdegen T. and Leah J. D. (1998) Inducible and constitutive transcription factors in the mammalian nervous system: control of gene expression by Jun, Fos and Krox, and CREB/AT proteins. Brain Res. Brain Res. Rev. 28, 370-490.
24. Herdegen T., Skene P., and Bahr M. (1997) The c-Jun transcription factor - biopotential mediator of neuronal death, survival and regeneration. Trends Neurosci. 20, 227-231.
25. Herdegen T., Claret F. X., Kallunki T., Martin-Villalba A., Winter C., Hunter T., and Karin M. (1998) Lasting N-terminal phosphorylation of c-Jun and activation of c-Jun N-terminal kinases after neuronal injury. J. Neurosci. 18, 5124-5135.
26. Hibi M., Lin A., Smeal T., Minden A., and Karin M. (1993) Identification of an oncoprotein-and UV-responsive protein kinase that binds and potentiates the c-Jun activation domain. Genes Dev. 7, 2135-2148.
27. Hirai S. I., Ryseck R. P., Mechta F., Bravo R., and Yaniv M. (1989) Characterization of JunD: a new member of the jun proto-oncogene family. EMBO J. 8, 1433-1439.
28. Hope B. T., Kelz M. B., Duman R. S., and Nestler E. J. (1994a) Chronic electroconvulsive seizure (ECS) treatment results in expression of a long-lasting AP-1 complex in brain with altered composition and characteristics. J. Neurosci. 14, 4318-4328.
29. Hope B. T., Nye H. E., Kelz M. B., Self D. W., Iadarola M. J., Nakabeppu Y., Duman R. S., and Nestler E. J. (1994b) Induction of a long-lasting AP-1 complex composed of altered Fos-like proteins in brain by chronic cocaine and other chronic treatments. Neuron 13, 1235-1244.
30. Hsu J. C., Cressman D. E., and Taub R. (1993) Promoter-specific trans-activation and inhibition mediated by JunB. Cancer Res. 53, 3789-3794.
31. Ivashkiv L. B., Liou H.-C., Kara C. J., Lamph W. W., Verma I. M., and Glimcher L. H. (1990) mXBP/CRE-BP2 and c-Jun form a complex which binds to the cyclic AMP, but not to the 12-O-tetradecanoylphorbol-13-acetate, response element. Mol. Cell. Biol. 10, 1609-1621.
32. Jacobs-Helber S. M., Wickrema A., Birrer M. J., and Sawyer S. T. (1998) AP1 regulation of proliferation and initiation of apoptosis in erythropoietin-dependent erythroid cells. Mol. Cell. Biol. 18, 3699-3707.
33. Jehn B. M. and Osborne B. A. (1997) Gene regulation associated with apoptosis. Crit. Rev. Eukaryot. Gene Expr. 7, 179-193.
34. Kaczmarek L. and Chaudhuri A. (1997) Sensory regulation of immediate-early gene expression in mammalian visual cortex: implications for functional mapping and neural plasticity. Brain Res. Rev. 23, 237-256.
35. Kallunki T., Deng T., Hibi M., and Karin M. (1996) c-Jun can recruit JNK to phosphorylate dimerization partners via specific docking interactions. Cell 87, 929-939.
36. Kaminska B., Filipkowski R. K., Zurkowska G., Lason W., Przewlocki R., and Kaczmarek L. (1994) Dynamic changes in the composition of the AP-1 transcription factor DNA-binding activity in rat brain following kainate-induced seizures and cell death. Eur. J. Neurosci. 6, 1558-1566.
37. Kaminska B., Mosieniak G., Gierdalski M., Kossut M., and Kaczmarek L. (1995) Elevated AP-1 transcription factor DNA binding activity at the onset of functional plasticity during developmenl of rat sensory cortical areas. Mol. Brain Res. 33, 295-304.
38. Kaminska B., Kaczmarek L., and Chaudhuri A. (1996) Visual stimulation regulates the expression of transcription factors and modulates the composition of AP-1 in visual cortex. J. Neurosci. 15, 3968-3978.
39. Karin M. (1995) The regulation of AP-1 activity by mitogen-activated protein kinases. J. Biol. Chem. 270, 16483-16486.
40. Kasibhatla S., Brunner T., Genestier L., Echeverri F., Mahboubi A., and Green D. R. (1998) DNA damaging agents induce expression of Fas ligand and subsequent apoptosis in T lymphocytes via the activation of NF-kappa B and AP-1. Mol. Cell 1, 43-51.
41. Kasof G. M., Mandelzys A., Maika S. D., Hammer R. E., Curran T., and Morgan J. I. (1995) Kainic acid-induced neuronal death is associated with DNA damage and a unique immediate-early gene response in c-fos-lacZ transgenic rats. J. Neurosci. 15, 4238-4249.
42. Kyriakis J. M., Banerjee P., Nikolakaki E., Dai T., Rubie E. A., Ahmad M. F., Avruch J., and Woodgett J. R. (1994) The stress-activated protein kinase subfamily of c-Jun kinases. Nature 369, 156-160.
43. Laemmli U. K. (1970) Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227, 680-685.
44. Lallemand D., Spyrou G., Yaniv M., and Pfarr C. M. (1997) Variations in Jun and Fos protein expression and AP-1 activity in cycling, resting and stimulated fibroblasts. Oncogene 14, 819-830.
45. Le-Niculescu H., Bonfoco E., Kasuya Y., Claret F.-X., Green D. R., and Karin M. (1999) Withdrawal of survival factors results in activation of the JNK pathway in neuronal cells leading to Fas ligand induction and cell death. Mol. Cell Biol. 19, 751-763.
46. Mechta F., Lallemand D., Pfarr C. M., and Yaniv M. (1997) Transformation by ras modifies API composition and activity. Oncogene 14, 837-847.
47. Minden A., Lin A., Smeal T., Derijard B., Cobb M., Davis R., and Karin M. (1994) c-Jun N-terminal phosphorylation correlates with activation of the JNK subgroup but not the ERK subgroup of mitogen-activated protein kinases. Mol. Cell. Biol. 14, 6683-6688.
48. Minden A., Lin A., Claret F.-X., Abo A., and Karin M. (1995) Selective activation of the JNK signaling cascade and c-Jun transcriptional activity by the small GTPases Rac and Cdc42Hs. Cell 81, 1147-1157.
49. Morgan J. I. and Curran T. (1995) Immediate-early genes: ten years on. Trends Neurosci. 18, 66-67.
50. Mosieniak G., Figiel I., and Kaminska B. (1997) Cyclosporin A, an immunosuppressive drug, induces programmed cell death in rat C6 glioma cells by a mechanism that involves the AP-1 transcription factor. J. Neurochem. 68, 1142-1149.
51. Mosieniak G., Pyrzynska B., and Kaminska B. (1998) Nuclear factor of activated T cells (NFAT) as a new component of the signal transduction pathway in glioma cells. J. Neurochem. 71, 134-141.
52. Pfarr C. M., Mechta F., Spyrou G., Lallemand D., Carillo S., and Yaniv M. (1994) Mouse JunD negatively regulates fibroblast growth and antagonizes transformation by ras. Cell 76, 747-760.
53. Pulverer B. J., Kyriakis J. M., Avruch J., Nikolakaki E., and Woodgett J. R. (1991) Phosphorylation of c-jun mediated by MAP kinases. Nature 353, 670-674.
54. Roffler-Tarlov S., Brown J. J., Tarlov E., Stolarov J., Chapman D. L., Alexiou M., and Papaioannou V. E. (1996) Programmed cell death in the absence of c-Fos and c-Jun. Development 122, 1-9.
55. Rutberg S. E., Saez E., Click A., Glugosz A. A., Spiegelman B. M., and Yuspa S. H. (1996) Differentiation of mouse keratinocytes is accompanied by PKC-dependent changes in AP-1 proteins. Oncogene 13, 167-176.
56. Rutberg S. E., Saez E., Lo S., Jang S. I., Markova N., Spiegelman B. M., and Yuspa S. H. (1997) Opposing activities of c-Fos and Fra-2 on AP-1 regulated transcriptional activity in mouse keratinocytes induced to differentiate by calcium and phorbol esters. Oncogene 15, 1337-1346.
57. Ryseck R. P. and Bravo R. (1991) c-JUN, JUN B, and JUN D differ in their binding affinities to AP-1 and CRE consensus sequences: effect of FOS proteins. Oncogene 6, 533-542.
58. Steller H. (1995) Mechanisms and genes of cellular suicide. Science 267, 1445-1462.
59. Virdee K., Bannister A. J., Hunt S. P., and Tolkovsky A. M. (1997) Comparison between the timing of JNK activation, c-Jun phosphorylation, and onset of death commitment in sympathetic neurones. J. Neurochem. 69, 550-561.
60. Watson A., Eilers A., Lallemand D., Kyriakis J., Rubin L. L., and Ham J. (1998) Phosphorylation of c-Jun is necessary for apoptosis induced by survival signal withdrawal in cerebellar granule neurons. J. Neurosci. 18, 751-762.
61. Williams G. T. (1993) Molecular regulation of apoptosis: genetic controls of cell death. Cell 74, 777-779.
62. Xia Z., Dickens M., Raingeaud J., Davis R. J., and Greenberg M. E. (1995) Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis. Science 270, 1326-1331.
63. Zhao B. H., Yu W. P., Qian M., Simmons-Menchaca M., Brown P. H., Birrer M. J., Sanders B. G., and Kline K. (1997) Involvement of activator protein-1 (AP-1) in induction of apoptosis by vitamin E succinate in human breast cancer cells. Mol. Carcinog. 19, 180-190.