Amygdalar injection of FeCl3 causes spontaneous recurrent seizures

Experimental Neurology

Volumn 153, Issue 1, 1998, Pages 123-127

  Ueda, Yuto ^a,b   Willmore, L James ^a   Triggs, William J ^c  

^a UNIVERSITY OF TEXAS MEDICAL SCHOOL   (United States)

^b UNIVERSITY OF MIYAZAKI   (Japan)

^c NONE

Author keywords

Amygdala; Electroencephalogram; Epileptiform; Ferric chloride; Kindling; Seizures

Indexed keywords

FERRIC CHLORIDE; CONVULSANT AGENT; FERRIC ION;

AMYGDALOID NUCLEUS; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ELECTROENCEPHALOGRAM; EPILEPTOGENESIS; HIPPOCAMPUS; LIPID PEROXIDATION; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; RAT; SEIZURE; ANIMAL; ANIMAL BEHAVIOR; CHEMICALLY INDUCED DISORDER; DRUG EFFECT; ELECTROENCEPHALOGRAPHY; MICROINJECTION; PHYSIOLOGY; RECURRENT DISEASE; SPRAGUE DAWLEY RAT; STEREOTAXIC SURGERY;

AMYGDALA; ANIMALS; BEHAVIOR, ANIMAL; CONVULSANTS; ELECTROENCEPHALOGRAPHY; FERRIC COMPOUNDS; LIPID PEROXIDATION; MICROINJECTIONS; RATS; RATS, SPRAGUE-DAWLEY; RECURRENCE; SEIZURES; STEREOTAXIC TECHNIQUES;

EID: 0031594856     PISSN: 00144886     EISSN: None     Source Type: Journal    
DOI: 10.1006/exnr.1998.6869     Document Type: Article

References (27)

1. Annegers, J. F., W. A. Hauser, S. P. Coan, and W. A. Rocca. 1998. A population-based study of seizures after traumatic brain injuries. N. Engl. J. Med. 338: 20-24.
2. Csernansky, J. G., C. A. Holman, K. A. Bonnet, K. Grabowsky, R. King, and L. E. Hollister. 1983. Dopaminergic supersensitivity at distant sites following induced epileptic foci. Life Sci. 32: 385-390.
3. Engel, J., L. Wolfson, and L. Brown. 1978. Anatomical correlates of electrical behavioral events related to amygdaloid kindling. Ann. Neurol. 3: 538-544.
4. Fisher, R. S. 1989. Animal models of the epilepsies. Brain Res. Rev. 14: 245-278.
5. Goddard, G. V. 1967. Development of epileptic seizures through brain stimulation at low intensity. Nature 214: 1020-1023.
6. Goddard, G. V., D. C. McIntyre, and C. K. Leech. 1969. A permanent change in brain function resulting from daily electrical stimulation. Exp. Neurol. 25: 295-330.
7. Hiyoshi, T., M. Seino, N. Kakagawa, T. Higashi, K. Yagi, and J. A. Wada. 1993. Evidence of secondary epileptogenesis in amygdaloid overkindled cats: Electroclinical documentation of spontaneous seizures. Epilepsia 34: 408-415.
8. Jennett, B. 1975. Epilepsy and acute traumatic intracranial haematoma. J. Neurol. Neurosurg. Psychiatry 38: 378-381.
9. Lothman, E. W., J. M. Hatlelid, and C. F. Zorumski. 1985. Functional mapping of limbic seizures originating in the hippocampus: A combined 2-deoxyglucose and electrophysiologic study. Brain Res. 362: 92-100.
10. Mathern, G. W., E. H. Bertram III, T. L. Babb, J. K. Pretorius, P. A. Kuhlman, S. Spradlin, and D. Mendoza. 1997. In contrast to kindled seizures, the frequency of spontaneous epilepsy in the limbic status model correlates with greater aberrant fascia dentata excitatory and inhibitory axon sprouting, and increased staining for n-methyl-d-aspartate, AMPA and GABAa receptors. Neuroscience 77: 1003-1019.
11. McNamara, J. 1986. Kindling model of epilepsy. Adv. Neurol. 44: 303-318.
12. Milgram, N. W., M. Michael, S. Cammisuli, E. Head, J. Ferbinteanu, C. Reid, M. P. Murphy, and R. Racine. 1995. Development of spontaneous seizures over extended electrical kindling. II. Persistence of dentate inhibitory suppression. Brain Res. 670: 112-120.
13. Moriwaki, A., Y. Hattori, N. Nishida, and Y. Hori. 1990. Electrocorticographic characterization of chronic iron-induced epilepsy in rats. Neurosci. Lett. 110: 72-76.
14. Pinel, J. P. J., and L. I. Rovner. 1978. Experimental epileptogenesis: kindling-induced epilepsy in rats. Exp. Neurol. 58: 190-202.
15. Pinel, J. P. J., and L. I. Rovner. 1978. Electrode placement and kindling-induced experimental epilepsy. Exp. Neurol. 58: 335-346.
16. Piredda, S., W. Yonekawa, T. S. Whittingham, and H. J. Kupferberg. 1986. Enhanced bursting activity in the CA3 region of the mouse hippocampal slice without long-term potentiation in the dentate gyrus after systemic pentylenetetrazole kindling. Exp. Neurol. 94: 659-669.
17. Racine, R. 1972. Modification of seizure activity by electrical stimulation. II. Motor seizure. Electroencephalogr. Clin. Neurophysiol. 32: 281-294.
18. Racine, R. J. 1972. Modification of seizure activity by electrical stimulation. I. After-discharge threshold. Electroencephalogr. Clin. Neurophysiol. 32: 269-279.
19. Sutula, T., C. Harrison, and O. Steward. 1986. Chronic epileptogenesis induced by kindling of the entorhinal cortex: The role of the dentate gyrus. Brain Res. 385: 291-299.
20. ++ injection. J. Neurochem. 42: 976-980.
21. Willmore, L. J. 1990. Posttraumatic epilepsy: Cellular mechanisms and implications for treatment. Epilepsia 31 (Suppl. 3): S67-S73.
22. 2 injection into rat isocortex. Brain Res. 277: 393-396.
23. 2 into rat isocortex. Brain Res. 246: 113-119.
24. Willmore, L. J., G. W. Sypert, and J. B. Munson. 1978. Recurrent seizures induced by cortical iron injection: a model of post-traumatic epilepsy. Ann. Neurol. 4: 329-336.
25. Willmore, L. J., G. W. Sypert, J. B. Munson, and R. W. Hurd. 1978. Chronic focal epileptiform discharges induced by injection of iron into rat and cat cortex. Science 200: 1501-1503.
26. Willmore, L. J., and W. J. Triggs. 1991. Iron-induced lipid peroxidation and brain injury responses. Int. J. Dev. Neurosci. 9: 175-180.
27. Willmore, L. J., W. J. Triggs, and J. D. Gray. 1986. The role of iron-induced hippocampal peroxidation in acute epileptogenesis. Brain Res. 382: 422-426.