Cytochrome p450 catalyzed nitric oxide synthesis: A theoretical study

Journal of Biomolecular Structure and Dynamics

Volumn 17, Issue 4, 2000, Pages 759-767

  Keserü, György M ^a,b   Volk, Balázs ^a   Balogh, György T ^a  

^a BUDAPEST UNIVERSITY OF TECHNOLOGY AND ECONOMICS   (Hungary)

^b GEDEON RICHTER LTD   (Hungary)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOCHROME P450; NITRIC OXIDE; NITRIC OXIDE SYNTHASE;

ARTICLE; CATALYSIS; ENZYME ACTIVITY; ENZYME CONFORMATION; ENZYME MECHANISM; PRIORITY JOURNAL; REACTION ANALYSIS; SYNTHESIS; X RAY CRYSTALLOGRAPHY;

STAPHYLOCOCCUS PHAGE 3A;

EID: 0033956152     PISSN: 07391102     EISSN: 15380254     Source Type: Journal    
DOI: 10.1080/07391102.2000.10506565     Document Type: Article

References (39)

1. Griffith, O. W., and Stuehr, D. J., 1995. Annu. Rev. Physiol., 57:707–736.
2. Ignarro, L. J., Buga, C. M., Wood, K. S., Byrns, R. W., and Chaudhuri, G., 1987. Proc. Natl. Acad. Sci. U.S.A., 84:9265–9269.
3. Palmer, R. M.J., Ferrige, A. G., and Moncada, S., 1987. Nature, 327:524–526.
4. Saavedra, J. M., Southan, G. J., Davies, K. M., Lundell, A., Hanson, S. R., Adrie, D., Hurford, W. E., Zapol, W. M., and Keefer, L. K., 1996. J. Med. Chem., 39:4361–4365.
5. Eich, R. F., Li, T., Lemon, D. D., Doherty, D. H., Curry, S. R., Aitken, J. F., Mathews, A. J., Johnson, K. A., Smith, R. D., Phillips, G. N., Jr. and Olson, J. S., Biochemistry, 356976–6983. (1996) and references therein
6. Green, I. C., and Charier, P. E., 1999. Drug Discover Today, 4:47–49.
7. Keefer, L. K., 1998. Modern Drug Discovery, 1:20–30.
8. Saavedra, J. E., Billiar, T. R., Williams, D. L., Kim, Y. M., Watkins, S. C., and Keefer, L. K., 1997. J. Med. Chem., 40:1947–1954.
9. Andronik-Lion, V., Boucher, J. L., Delaforge, M., Henry, Y., and Mansuy, D., 1992. Biochem. Biophys. Res. Commun., 185:452–458.
10. Boucher, J. L., Genet, A., Vadon, S., Delaforge, M., Henry, Y., and Mansuy, D., 1992. Biochem. Biophys. Res. Commun., 187:880–886.
11. Boucher, J. L., Genet, A., Vadon, S., Delaforge, M., and Mansuy, D., 1992. Biochem. Biophys. Res. Commun., 184:1158–1164.
12. Renaud, J. P., Boucher, J. L., Vadon, S., Delaforge, M., and Mansuy, D., 1993. Biochem. Biophys. Res. Commun., 192:53–60.
13. Clement, B., and Jung, F., 1994. Drug Metab. Disp., 22:486–497.
14. Clement, B., Shultze-Mosgau, M. H., and Wohlers, H., 1993. Biochem. Pharmacol., 46:2249–2267.
15. Crane, B. R., Arvai, A. S., Gachhui, R., Wu, C., Ghosh, D. K., Getzoff, E. D., Stuehr, D. J., and Tainer, J. A., 1997. Science, 278:425–431.
16. Crane, R., Arvai, A. S., Ghosh, D. K., Wu, C., Getzoff, E. D., Stuehr, D. J., and Tainer, J. A., 1998. Science, 279:2121–2125.
17. Ravichandran, K. G., Boddupalli, S. S., Haseman, C. A., Peterson, J. A., and Deisenhofer, J., 1993. Science, 261:731–736.
18. Hasemann, C. A., Ravichandran, K. G., Peterson, J. A., and Deisenhofer, J., 1994. J. Mol. Biol., 236:1169–1185.
19. Sali, A., and Blundell, T. L., 1993. J. Mol. Biol., 134:779–815.
20. Sanchez, R., and Sali, A., 1997. Curr. Opin. Struct. Biol., 7:206–214.
21. Gérczei, T., Keserû, G. M., and Naray-Szabó, G., J. Mol. Graph., submitted for publication
22. Laskowski, R. A., MacArthur, M. W., Moss, D. S., and Thornton, J. M., 1993. J. Appl. Cryst., 26:283–291.
23. Szklarz, G. D., and Halper, J. R., 1997. J. Comp. Aided Mol. Des., 11:265–272.
24. McDonald, D. Q., and Still, W. C., 1992. Tetrahedron Lett., 33:7743–7746.
25. Mohamadi, F., Richards, N. G.J., Guida, W. C., Liskamp, R., Lipton, M., Caufield, C., Chang, G., Hendrickson, T., and Still, W. C., 1990. J. Comput. Chem., 11:440–467.
26. Whitlow, M., and Teeter, M. M., 1986. J. Am. Chem. Soc., 108:7163–7172.
27. Keserü, G. M., Kolossváry, I., and Bertók, B., 1986. J. Am. Chem. Soc., 108:7163–7172.
28. Manchester, J. I., Paulsen, M. D., and Ornstein, R., 1995. Modeling of Biomolecular Structures and Mechanisms Edited by:Pullman, A., 181 (–188. Kluwer, The Netherlands
29. Keserû, G. M., Kolossváry, I., and Székely, I., 1999. Int. J. Quant. Chem., 73:123–135.
30. Keserû, G. M., and Menyhárd, D. K., 1999. Biochemistry, 38:6614–6622.
31. Keserû, G. M., and Kolossváry, I., 1999. Molecular Mechanics and Conformational Analysis in Drug Design UK:Blackwell Science.
32. Exner, T., Keil, M., Moeckel, G., and Brickmann, J., 1998. J. Mol. Model., 4:340–343.
33. Brickmann, J., Goetze, T., Heiden, W., Moeckel, G., Reiling, S., Vollhardt, H., and Zachmann, C. D., 1995. Data Visualisation in Molecular Science:Tools for Insight and Innovation Edited by:Bowie, J. E., 83–97. Reading Mass:Addison-Wesley Publishing Company Inc.
34. Sybyl 6.5, TRIPOS, Inc. 1699 South Hanley Road, Suite 303 St. Louis, Missouri 63144–2913, USA
35. Holtje, H. D., and Folkers, G., 1997. Molecular Modeling. Basic Principles and Applications VCH Weinheim. see eg. in
36. Chang, Y. T., and Loew, G. H., 1996. Protein Engineering, 9:755–766. and references therein
37. He, Y. A., He, Y. Q., Szklarz, G. D., and Halpert, J. R., 1997. Biochemistry, 36:8831–8839.
38. Wang, H., Dick, R., Yin, H., Licad-Coles, E., Kroetz, D. L., Szklarz, G. D., Harlow, G., Halpert, J. R., and Correia, M. A., 1998. Biochemistry, 37:12536–12545.
39. available at http://www.rcsb.org/pdb