Escherichia coli cytosine deaminase: The kinetics and thermodynamics for binding of cytosine to the apoenzyme and the Zn2+ holoenzyme are similar

Biochimica et Biophysica Acta - Protein Structure and Molecular Enzymology

Volumn 1476, Issue 2, 2000, Pages 239-252

  Porter, David J T ^a  

^a GLAXOSMITHKLINE   (United States)

Author keywords

Apoenzyme; Cytosine deaminase; Dissociation constant; Holoenzyme; Pre steady state kinetics

Indexed keywords

APOENZYME; CYTOSINE DEAMINASE; FLUCYTOSINE; FLUOROURACIL; HOLOENZYME; PHENANTHROLINE DERIVATIVE; ZINC;

ARTICLE; DEAMINATION; ENZYME ACTIVITY; ENZYME BINDING; ESCHERICHIA COLI; PLASMID; PRIORITY JOURNAL; SPECTROPHOTOMETRY; STATISTICAL ANALYSIS; STEADY STATE; THERMODYNAMICS;

BACTERIAL PROTEINS; CYTOSINE; CYTOSINE DEAMINASE; ESCHERICHIA COLI; KINETICS; NUCLEOSIDE DEAMINASES; RECOMBINANT PROTEINS; SUBSTRATE SPECIFICITY; THERMODYNAMICS; ZINC;

EID: 0033953971     PISSN: 01674838     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0167-4838(99)00246-0     Document Type: Article

References (32)

1. Katsuragi T., Sonoda T., Matsumoto K., Sakai T., Tonomura K. Agric. Biol. Chem. 53:1989;1313-1319.
2. Katsuragi T., Sakai T., Matsumoto K., Kenzo T. Agric. Biol. Chem. 50:1986;1721-1730.
3. Nishiyama T., Kawamura Y., Kawamoto K., Matsumura H., Yamamoto N., Ito T., Ohyama A., Katsuragi T., Sakai T. Cancer Res. 45:1985;1753-1761.
4. Mullen C.A., Kilstrup M., Blaese R.M. Proc. Natl. Acad. Sci. USA. 89:1992;33-37.
5. Austin E.A., Huber B.E. Mol. Pharmacol. 43:1993;380-387.
6. Dachs G.U., Dougherty G.J., Stratford I.J., Chaplin D.J. Oncol. Res. 9:1997;313-325.
7. Sherwood R.F. Adv. Drug Deliv. Rev. 22:1996;269-288.
8. Crystal R.G., Hirschowitz E., Lieberman M., Daly J., Kazam E., Henschke C., Yankelevitz D., Kemeny N., Silverstein R., Ohwada A., Russi T., Mastrangeli A., Sanders A., Cooke J., Harvey B.G. Hum. Gene Ther. 8:1997;985-1001.
9. Porter D.J.T., Austin E.A. J. Biol. Chem. 268:1993;24005-24011.
10. Esders T.W., Lynn S.Y. J. Biol. Chem. 260:1985;3915-3922.
11. Bhaumik D., Medin J., Gathy K., Coleman M.S. J. Biol. Chem. 268:1993;5464-5470.
12. Mohamedali K.A., Kurz L.C., Rudolph F.B. Biochemistry. 35:1996;1672-1680.
13. Smith A.A., Carlow D.C., Wolfenden R., Short S.A. Biochemistry. 33:1994;6468-6474.
14. Porter D.J.T., Spector T. J. Biol. Chem. 268:1993;2480-2485.
15. Porter D.J.T. J. Biol. Chem. 273:1998;14247-14253.
16. Zielke C.L., Suelter C.H. J. Biol. Chem. 246:1971;2179-2186.
17. Wilson D.K., Rudolph F.B., Quiocho F.A. Science. 252:1991;1278-1284.
18. Wilson D.K., Quiocho F.A. Biochemistry. 32:1993;1689-1694.
19. Kurz L.C., Moix L., Riley M.C., Freiden C. Biochemistry. 31:1992;39-48.
20. Yang C., Carlow D., Wolfenden R., Short S. Biochemistry. 31:1992;4168-4174.
21. Betts L., Xaing S., Short S.A., Wolfenden R., Carter C.W. Jr. J. Mol. Biol. 235:1994;635-656.
22. Xiang S., Short S.A., Wolfenden R., Carter C.W. Jr. Biochemistry. 35:1996;1335-1341.
23. Navaratnam N., Morrison J.R., Bhattacharya S., Patel D., Funahashi T., Giannoni F., Teng B.B., Davidson N.O., Scott J.R. J. Biol. Chem. 268:1993;20709-20712.
24. Moore J.T., Silversmith R.E., Maley G.F., Maley F. J. Biol. Chem. 268:1993;2288-2291.
25. Yoshino M., Marakami K., Tusushima K. Biochem. Pharmacol. 27:1978;2651-2652.
26. Holm L., Sander C. Proteins. 28:1997;72-82.
27. Sadowsky M.J., Tong Z., de Souza M., Wackett L.P. J. Bacteriol. 180:1998;152-158.
28. Carlow D.C., Short S.A., Wolfenden R. Biochemistry. 35:1996;948-954.
29. Jones W., Kurz L.C., Wolfenden R. Biochemistry. 28:1989;1242-1247.
30. Wilson D.K., Quiocho F.A. Nat. Struct. Biol. 1:1994;691-694.
31. Shih P., Wolfenden R. Biochemistry. 35:1996;4697-4703.
32. Caiolfa V.R., Gill D., Parola A.H. FEBS Lett. 260:1990;19-22.