Role of glutamate-104 in generating a transition state analogue inhibitor at the active site of cytidine deaminase

Biochemistry

Volumn 35, Issue 3, 1996, Pages 948-954

  Carlow, Dean C ^a   Short, Steven A ^b   Wolfenden, Richard ^a  

^a UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^b GLAXOSMITHKLINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYTIDINE DEAMINASE; FLUOROPYRIMIDINE DERIVATIVE; FLUOROURIDINE;

AMINO ACID SUBSTITUTION; ARTICLE; CONFORMATIONAL TRANSITION; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME CONFORMATION; ENZYME STABILITY; ESCHERICHIA COLI; GENE MUTATION; HYDRATION; NONHUMAN; NUCLEAR MAGNETIC RESONANCE; PRIORITY JOURNAL; STRUCTURE ACTIVITY RELATION;

BINDING SITES; CYTIDINE DEAMINASE; ENZYME INHIBITORS; FLUORESCENCE; GLUTAMIC ACID; MAGNETIC RESONANCE SPECTROSCOPY; SPECTROPHOTOMETRY, ULTRAVIOLET;

EID: 0030066275     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi951498y     Document Type: Article

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