메뉴 건너뛰기




Volumn 6, Issue 2, 2000, Pages 681-692

Induction of apoptosis in malignant B cells by phenylbutyrate or phenylacetate in combination with chemotherapeutic agents

Author keywords

[No Author keywords available]

Indexed keywords

ANTIINFECTIVE AGENT; ARYLBUTYRIC ACID DERIVATIVE; CARBOPLATIN; CHLORAMBUCIL; CISPLATIN; CYTARABINE; DOXORUBICIN; ETOPOSIDE; FLUDARABINE; MELPHALAN; PHENYLACETIC ACID; TOPOTECAN;

EID: 0033952555     PISSN: 10780432     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (54)

References (77)
  • 2
    • 0019319139 scopus 로고
    • Amino acid acylation: A mechanism of nitrogen excretion in inborn errors of urea synthesis
    • Brusilow, S., Tinker, J., and Batshaw, M. Amino acid acylation: a mechanism of nitrogen excretion in inborn errors of urea synthesis. Science (Washington DC), 207: 659-661, 1980.
    • (1980) Science (Washington DC) , vol.207 , pp. 659-661
    • Brusilow, S.1    Tinker, J.2    Batshaw, M.3
  • 4
    • 0026029242 scopus 로고
    • Phenylacetylglutamine may replace urea as a vehicle for waste nitrogen excretion
    • Brusilow, S. Phenylacetylglutamine may replace urea as a vehicle for waste nitrogen excretion. Pediatr. Res., 29: 147-150, 1991.
    • (1991) Pediatr. Res. , vol.29 , pp. 147-150
    • Brusilow, S.1
  • 5
    • 0026636474 scopus 로고
    • Phenylacetate: A novel nontoxic inducer of tumor cell differentiation
    • Samid, D., Shack, S., and Sherman, L. Phenylacetate: a novel nontoxic inducer of tumor cell differentiation. Cancer Res., 52: 1988-1992, 1992.
    • (1992) Cancer Res. , vol.52 , pp. 1988-1992
    • Samid, D.1    Shack, S.2    Sherman, L.3
  • 6
    • 0033564130 scopus 로고    scopus 로고
    • Inhibitors of histone deacetylase relieve ETO-mediated repression and induce differentiation of AML1-ETO leukemia cells
    • Wang, J., Saunthararajah, Y., Redner, R., and Liu, J. Inhibitors of histone deacetylase relieve ETO-mediated repression and induce differentiation of AML1-ETO leukemia cells. Cancer Res., 59: 2766-2769, 1999.
    • (1999) Cancer Res. , vol.59 , pp. 2766-2769
    • Wang, J.1    Saunthararajah, Y.2    Redner, R.3    Liu, J.4
  • 7
    • 0028210550 scopus 로고
    • Selective activity of phenylacetate against malignant gliomas: Resemblance to fetal brain damage in phenylketonuria
    • Samid, D., Ram, Z., Hudgins, W. R., Shack, S., Liu, L., Walbridge, S., Oldfield, E. H., and Myers, C. E. Selective activity of phenylacetate against malignant gliomas: resemblance to fetal brain damage in phenylketonuria. Cancer Res., 54: 891-895, 1994.
    • (1994) Cancer Res. , vol.54 , pp. 891-895
    • Samid, D.1    Ram, Z.2    Hudgins, W.R.3    Shack, S.4    Liu, L.5    Walbridge, S.6    Oldfield, E.H.7    Myers, C.E.8
  • 8
    • 0031950725 scopus 로고    scopus 로고
    • Inhibitory effects of phenylbutyrate on the proliferation, morphology, migration and invasiveness of malignant glioma cells
    • Engelhard, H. H., Homer, R. J., Duncan, H. A., and Rozental, J. Inhibitory effects of phenylbutyrate on the proliferation, morphology, migration and invasiveness of malignant glioma cells. J. Neuro-oncol., 37: 97-108, 1998.
    • (1998) J. Neuro-oncol. , vol.37 , pp. 97-108
    • Engelhard, H.H.1    Homer, R.J.2    Duncan, H.A.3    Rozental, J.4
  • 11
    • 0030861882 scopus 로고    scopus 로고
    • Impact of the putative differentiating agents sodium phenylbutyrate and sodium phenylacetate on proliferation, differentiation, and apoptosis of primary neoplastic myeloid cells
    • Gore, S. D., Samid, D., and Weng, L. J. Impact of the putative differentiating agents sodium phenylbutyrate and sodium phenylacetate on proliferation, differentiation, and apoptosis of primary neoplastic myeloid cells. Clin. Cancer Res., 3: 1755-1762, 1997.
    • (1997) Clin. Cancer Res. , vol.3 , pp. 1755-1762
    • Gore, S.D.1    Samid, D.2    Weng, L.J.3
  • 12
    • 0031723393 scopus 로고    scopus 로고
    • Enhanced growth inhibition and differentiation of fluorodeoxyuridine-treated human colon carcinoma cells by phenylbutyrate
    • Huang, Y., and Waxman, S. Enhanced growth inhibition and differentiation of fluorodeoxyuridine-treated human colon carcinoma cells by phenylbutyrate. Clin. Cancer Res., 4: 2503-2509, 1998.
    • (1998) Clin. Cancer Res. , vol.4 , pp. 2503-2509
    • Huang, Y.1    Waxman, S.2
  • 13
    • 0025910547 scopus 로고
    • Effect of phenylalanine derivatives on the main regulatory enzymes of hepatic cholesterolgenesis
    • Castillo, M., Martinez-Cayuela, M., Zafra, M., and Garcia-Peregrin, E. Effect of phenylalanine derivatives on the main regulatory enzymes of hepatic cholesterolgenesis. Mol. Cell. Biochem., 105: 21-25, 1991.
    • (1991) Mol. Cell. Biochem. , vol.105 , pp. 21-25
    • Castillo, M.1    Martinez-Cayuela, M.2    Zafra, M.3    Garcia-Peregrin, E.4
  • 14
    • 0029999619 scopus 로고    scopus 로고
    • Activation of a human peroxisome proliferator-activated receptor by the antitumor agent phenylacetate and its analogs
    • Pineau, T., Hudgins, W. R., Liu, L., Chen, L. C., Sher, T., Gonzalez, F. J., and Samid, D. Activation of a human peroxisome proliferator-activated receptor by the antitumor agent phenylacetate and its analogs. Biochem. Pharmacol., 52: 659-667, 1996.
    • (1996) Biochem. Pharmacol. , vol.52 , pp. 659-667
    • Pineau, T.1    Hudgins, W.R.2    Liu, L.3    Chen, L.C.4    Sher, T.5    Gonzalez, F.J.6    Samid, D.7
  • 15
    • 0027284950 scopus 로고
    • Protein prenylation: A mediator of protein-protein interactions
    • Marshall, C. Protein prenylation: a mediator of protein-protein interactions. Science (Washington DC), 259: 1865-1866, 1993.
    • (1993) Science (Washington DC) , vol.259 , pp. 1865-1866
    • Marshall, C.1
  • 16
    • 0028802943 scopus 로고
    • Cytostatic activity of phenylacetate and derivatives against tumor cells. Correlation with lipophilicity and inhibition of protein prenylation
    • Hudgins, W. R., Shack, S., Myers, C. E., and Samid, D. Cytostatic activity of phenylacetate and derivatives against tumor cells. Correlation with lipophilicity and inhibition of protein prenylation. Biochem. Pharmacol., 50: 1273-1279, 1995.
    • (1995) Biochem. Pharmacol. , vol.50 , pp. 1273-1279
    • Hudgins, W.R.1    Shack, S.2    Myers, C.E.3    Samid, D.4
  • 17
    • 0029892886 scopus 로고    scopus 로고
    • Phenylacetate inhibits protein isoprenylation and growth of the androgen-independent LNCaP prostate cancer cells transfected with the T24 Ha-ras oncogene
    • Danesi, R., Nardini, D., Basolo, F., Del Tacca, M., Samid, D., and Myers, C. E. Phenylacetate inhibits protein isoprenylation and growth of the androgen-independent LNCaP prostate cancer cells transfected with the T24 Ha-ras oncogene. Mol. Pharmacol., 49: 972-979, 1996.
    • (1996) Mol. Pharmacol. , vol.49 , pp. 972-979
    • Danesi, R.1    Nardini, D.2    Basolo, F.3    Del Tacca, M.4    Samid, D.5    Myers, C.E.6
  • 18
    • 0028794024 scopus 로고
    • Increased susceptibility of ras-transformed cells to phenylacetate is associated with inhibition of p21ras isoprenylation and phenotypic reversion
    • Shack, S., Chen, L. C., Miller, A. C., Danesi, R., and Samid, D. Increased susceptibility of ras-transformed cells to phenylacetate is associated with inhibition of p21ras isoprenylation and phenotypic reversion. Int. J. Cancer, 63: 124-129, 1995.
    • (1995) Int. J. Cancer , vol.63 , pp. 124-129
    • Shack, S.1    Chen, L.C.2    Miller, A.C.3    Danesi, R.4    Samid, D.5
  • 19
    • 0028812772 scopus 로고
    • Sodium phenylacetate induces growth inhibition and Bcl-2 down-regulation and apoptosis in MCF7ras cells in vitro and in nude mice
    • Adam, L., Crepin, M., Savin, C., and Israel, L. Sodium phenylacetate induces growth inhibition and Bcl-2 down-regulation and apoptosis in MCF7ras cells in vitro and in nude mice. Cancer Res., 55: 5156-5160, 1995.
    • (1995) Cancer Res. , vol.55 , pp. 5156-5160
    • Adam, L.1    Crepin, M.2    Savin, C.3    Israel, L.4
  • 20
    • 1842413054 scopus 로고    scopus 로고
    • Tumor growth inhibition, apoptosis, and bcl-2 down-regulation of MCF-7ras tumors by sodium phenylacetate and tamoxifen combination
    • Adam, L., Crepin, M., and Israel, L. Tumor growth inhibition, apoptosis, and bcl-2 down-regulation of MCF-7ras tumors by sodium phenylacetate and tamoxifen combination. Cancer Res., 57: 1023-1029, 1997.
    • (1997) Cancer Res. , vol.57 , pp. 1023-1029
    • Adam, L.1    Crepin, M.2    Israel, L.3
  • 21
    • 0029829031 scopus 로고    scopus 로고
    • Up-regulation and functional role of p21Waf1/Cip1 during growth arrest of human breast carcinoma MCF-7 cells by phenylacetate
    • Gorospe, M., Shack, S., Guyton, K. Z., Samid, D., and Holbrook, N. J. Up-regulation and functional role of p21Waf1/Cip1 during growth arrest of human breast carcinoma MCF-7 cells by phenylacetate. Cell Growth Differ., 7: 1609-1615, 1996.
    • (1996) Cell Growth Differ. , vol.7 , pp. 1609-1615
    • Gorospe, M.1    Shack, S.2    Guyton, K.Z.3    Samid, D.4    Holbrook, N.J.5
  • 22
    • 0026710710 scopus 로고
    • Increased fetal hemoglobin in patients receiving sodium 4-phenylbutyrate
    • Dover, G., Brusilow, S., and Samid, D. Increased fetal hemoglobin in patients receiving sodium 4-phenylbutyrate. N. Engl. J. Med., 327: 569-570, 1992.
    • (1992) N. Engl. J. Med. , vol.327 , pp. 569-570
    • Dover, G.1    Brusilow, S.2    Samid, D.3
  • 23
    • 0028303870 scopus 로고
    • Induction of fetal hemoglobin production in subjects with sickle cell anemia by oral sodium phenylbutyrate
    • Dover, G. J., Brusilow, S., and Charache, S. Induction of fetal hemoglobin production in subjects with sickle cell anemia by oral sodium phenylbutyrate. Blood, 84: 339-343, 1994.
    • (1994) Blood , vol.84 , pp. 339-343
    • Dover, G.J.1    Brusilow, S.2    Charache, S.3
  • 25
    • 0029032965 scopus 로고
    • Extended therapy with intravenous arginine butyrate in patients with β-hemoglobinopathies
    • Sher, G., Ginder, G., Little, J., Yang, S., Dover, G., and Olivieri, N. Extended therapy with intravenous arginine butyrate in patients with β-hemoglobinopathies. N. Engl. J. Med., 332: 1606-1610, 1995.
    • (1995) N. Engl. J. Med. , vol.332 , pp. 1606-1610
    • Sher, G.1    Ginder, G.2    Little, J.3    Yang, S.4    Dover, G.5    Olivieri, N.6
  • 26
    • 0031889082 scopus 로고    scopus 로고
    • A pilot clinical trial of oral sodium 4-phenylbutyrate (buphenyl) in 8F508-homozygous cystic fibrosis patients: Partial restoration of nasal epithelial CFTR function
    • Rubenstein, R. C., and Zeitlin, P. L. A pilot clinical trial of oral sodium 4-phenylbutyrate (buphenyl) in 8F508-homozygous cystic fibrosis patients: partial restoration of nasal epithelial CFTR function. Am. J. Respir. Crit. Care Med., 757: 484-490, 1998.
    • (1998) Am. J. Respir. Crit. Care Med. , vol.757 , pp. 484-490
    • Rubenstein, R.C.1    Zeitlin, P.L.2
  • 27
    • 0029937059 scopus 로고    scopus 로고
    • Vulnerability of multidrug-resistant tumor cells to the aromatic fatty acids phenylacetate and phenylbutyrate
    • Shack, S., Miller, A., Liu, L., Prasanna, P., Thibault, A., and Samid, D. Vulnerability of multidrug-resistant tumor cells to the aromatic fatty acids phenylacetate and phenylbutyrate. Clin. Cancer Res., 2: 865-872, 1996.
    • (1996) Clin. Cancer Res. , vol.2 , pp. 865-872
    • Shack, S.1    Miller, A.2    Liu, L.3    Prasanna, P.4    Thibault, A.5    Samid, D.6
  • 31
    • 0026772298 scopus 로고
    • Effect of p-glycoprotein expression on the accumulation and cytotoxicity of topotecan (SK&F 104864), a new camptothecin analogue
    • Hendricks, C., Rowinsky, E., Grochow, L., Donehower, R., and Kaufmann, S. Effect of p-glycoprotein expression on the accumulation and cytotoxicity of topotecan (SK&F 104864), a new camptothecin analogue. Cancer Res., 52: 2268-2278, 1992.
    • (1992) Cancer Res. , vol.52 , pp. 2268-2278
    • Hendricks, C.1    Rowinsky, E.2    Grochow, L.3    Donehower, R.4    Kaufmann, S.5
  • 32
    • 0025326586 scopus 로고
    • Chemosensitivity testing of fresh human leukemia cells using both a dye exclusion assay and a tetrazolium dye (MTT) assay
    • Kirkpatrick, D., Duke, M., and Goh, T. Chemosensitivity testing of fresh human leukemia cells using both a dye exclusion assay and a tetrazolium dye (MTT) assay. Leuk. Res., 14: 459-466, 1990.
    • (1990) Leuk. Res. , vol.14 , pp. 459-466
    • Kirkpatrick, D.1    Duke, M.2    Goh, T.3
  • 33
    • 0031181228 scopus 로고    scopus 로고
    • A role for insulin-like growth factor in the regulation of IL-6-responsive human myeloma cell line growth
    • Jelinek, D., Witzig, T., and Arendt, B. A role for insulin-like growth factor in the regulation of IL-6-responsive human myeloma cell line growth. J. Immunol., 159: 487-496, 1997.
    • (1997) J. Immunol. , vol.159 , pp. 487-496
    • Jelinek, D.1    Witzig, T.2    Arendt, B.3
  • 34
    • 0029866409 scopus 로고    scopus 로고
    • The use of 7-aminoactinomycin D in identifying apoptosis: Simplicity of use and broad spectrum of application compared with other techniques
    • Philpott, N., Turner, A., Scopes, J., Westby, M., Marsh, J., Gordon-Smith, E., Dalgleish, A., and Gibson, F. The use of 7-aminoactinomycin D in identifying apoptosis: simplicity of use and broad spectrum of application compared with other techniques. Blood, 87: 2244-2251, 1996.
    • (1996) Blood , vol.87 , pp. 2244-2251
    • Philpott, N.1    Turner, A.2    Scopes, J.3    Westby, M.4    Marsh, J.5    Gordon-Smith, E.6    Dalgleish, A.7    Gibson, F.8
  • 35
    • 0024313362 scopus 로고
    • Additional members of the rat liver lamin polypeptide family. Structural and immunological characterization
    • Kaufmann, S. H. Additional members of the rat liver lamin polypeptide family. Structural and immunological characterization. J. Biol. Chem., 264: 13946-13955, 1989.
    • (1989) J. Biol. Chem. , vol.264 , pp. 13946-13955
    • Kaufmann, S.H.1
  • 39
    • 0030812207 scopus 로고    scopus 로고
    • Cytotoxic synergy between flavopiridol (NSC 649890, L86-8275) and various antineoplastic agents: The importance of sequence of administration
    • Bible, K., and Kaufmann, S. Cytotoxic synergy between flavopiridol (NSC 649890, L86-8275) and various antineoplastic agents: the importance of sequence of administration. Cancer Res., 57: 3375-3380, 1997.
    • (1997) Cancer Res. , vol.57 , pp. 3375-3380
    • Bible, K.1    Kaufmann, S.2
  • 40
    • 0021118703 scopus 로고
    • Quantitative analysis of dose-effective relationships: The combined effects of multiple drugs or enzyme inhibitors
    • Chou, T-C., and Talalay, P. Quantitative analysis of dose-effective relationships: the combined effects of multiple drugs or enzyme inhibitors. Adv. Enzyme Regul., 22: 27-55, 1984.
    • (1984) Adv. Enzyme Regul. , vol.22 , pp. 27-55
    • Chou, T.-C.1    Talalay, P.2
  • 41
    • 0028870221 scopus 로고
    • Oral sodium phenylbutyrate therapy in homozygous β thalassemia: A clinical trial
    • Collins, A. F., Pearson, H. A., Giardina, P., McDonagh, K. T., Brusilow, S. W., and Dover, G. J. Oral sodium phenylbutyrate therapy in homozygous β thalassemia: a clinical trial. Blood, 85: 43-49, 1995.
    • (1995) Blood , vol.85 , pp. 43-49
    • Collins, A.F.1    Pearson, H.A.2    Giardina, P.3    McDonagh, K.T.4    Brusilow, S.W.5    Dover, G.J.6
  • 44
    • 0032885388 scopus 로고    scopus 로고
    • Mammalian caspases: Structure, activation, substrates and functions during apoptosis
    • Earnshaw, W., Martins, L., and Kaufmann, S. Mammalian caspases: structure, activation, substrates and functions during apoptosis. Annu. Rev. Biochem., 68: 383-424, 1999.
    • (1999) Annu. Rev. Biochem. , vol.68 , pp. 383-424
    • Earnshaw, W.1    Martins, L.2    Kaufmann, S.3
  • 49
    • 0029786498 scopus 로고    scopus 로고
    • Long-term treatment of girls with ornithine transcarbamylase deficiency
    • Maestri, N. E., Brusilow, S. W., Clissold, D. B., and Bassett, S. S. Long-term treatment of girls with ornithine transcarbamylase deficiency. N. Engl. J. Med., 335: 855-859, 1996.
    • (1996) N. Engl. J. Med. , vol.335 , pp. 855-859
    • Maestri, N.E.1    Brusilow, S.W.2    Clissold, D.B.3    Bassett, S.S.4
  • 50
    • 0025988177 scopus 로고
    • Interferon in combination with antitumourigenic phenyl derivatives: Potentiation of IFNα activity in vitro
    • Samid, D., Yeh, T-J., and Shack, S. Interferon in combination with antitumourigenic phenyl derivatives: potentiation of IFNα activity in vitro. Br. J. Haematol., 79 (Suppl 1): 81-83, 1991.
    • (1991) Br. J. Haematol. , vol.79 , Issue.SUPPL. 1 , pp. 81-83
    • Samid, D.1    Yeh, T.-J.2    Shack, S.3
  • 51
    • 0028238226 scopus 로고
    • In vitro antitumor effect of hydroxyurea on hormone-refractory prostate cancer cells and its potentiation by phenylbutyrate
    • Figg, W. D., Walls, R. G., Cooper, M. R., Thibault, A., Sartor, O., McCall, N. A., Myers, C. E., and Samid, D. In vitro antitumor effect of hydroxyurea on hormone-refractory prostate cancer cells and its potentiation by phenylbutyrate. Anticancer Drugs, 5: 336-342, 1994.
    • (1994) Anticancer Drugs , vol.5 , pp. 336-342
    • Figg, W.D.1    Walls, R.G.2    Cooper, M.R.3    Thibault, A.4    Sartor, O.5    McCall, N.A.6    Myers, C.E.7    Samid, D.8
  • 52
    • 0029737436 scopus 로고    scopus 로고
    • Enhancement of sensitivity of human lung adenocarcinoma cells to growth-inhibitory activity of interferon α by differentiation-inducing agents
    • Goto, I., Yamamoto-Yamaguchi, Y., and Honma, Y. Enhancement of sensitivity of human lung adenocarcinoma cells to growth-inhibitory activity of interferon α by differentiation-inducing agents. Br. J. Cancer, 74: 546-554, 1996.
    • (1996) Br. J. Cancer , vol.74 , pp. 546-554
    • Goto, I.1    Yamamoto-Yamaguchi, Y.2    Honma, Y.3
  • 53
    • 0028898487 scopus 로고
    • Phenylacetate synergizes with retinoic acid in inducing the differentiation of human neuroblastoma cells
    • Sidell, N., Wada, R., Han, G., Chang, B., Shack, S., Moore, T., and Samid, D. Phenylacetate synergizes with retinoic acid in inducing the differentiation of human neuroblastoma cells. Int. J. Cancer, 60: 507-514, 1995.
    • (1995) Int. J. Cancer , vol.60 , pp. 507-514
    • Sidell, N.1    Wada, R.2    Han, G.3    Chang, B.4    Shack, S.5    Moore, T.6    Samid, D.7
  • 54
    • 0031873481 scopus 로고    scopus 로고
    • Transcriptional up-regulation of retinoic acid receptor β (RAR β) expression by phenylacetate in human neuroblastoma cells
    • Sidell, N., Chang, B., Yamashiro, J. M., and Wada, R. K. Transcriptional up-regulation of retinoic acid receptor β (RAR β) expression by phenylacetate in human neuroblastoma cells. Exp. Cell Res., 239: 169-174, 1998.
    • (1998) Exp. Cell Res. , vol.239 , pp. 169-174
    • Sidell, N.1    Chang, B.2    Yamashiro, J.M.3    Wada, R.K.4
  • 55
    • 0031939919 scopus 로고    scopus 로고
    • Cytotoxic effects of sodium phenylbutyrate on human neuroblastoma cell lines
    • Pelidis, M. A., Carducci, M. A., and Simons, J. W. Cytotoxic effects of sodium phenylbutyrate on human neuroblastoma cell lines. Int. J. Oncol., 12: 889-893, 1998.
    • (1998) Int. J. Oncol. , vol.12 , pp. 889-893
    • Pelidis, M.A.1    Carducci, M.A.2    Simons, J.W.3
  • 58
    • 3643104150 scopus 로고    scopus 로고
    • Therapeutic targeting of transcription in acute promyelocytic leukemia by use of an inhibitor of histone deacetylase
    • Warrell, R. P., Jr., He, L. Z., Richon, V., Calleja, E., and Pandolfi, P. P. Therapeutic targeting of transcription in acute promyelocytic leukemia by use of an inhibitor of histone deacetylase. J. Natl. Cancer Inst., 90: 1621-1625, 1998.
    • (1998) J. Natl. Cancer Inst. , vol.90 , pp. 1621-1625
    • Warrell R.P., Jr.1    He, L.Z.2    Richon, V.3    Calleja, E.4    Pandolfi, P.P.5
  • 59
    • 0020532855 scopus 로고
    • Plasma pharmacokinetics of Adriamycin and Adriamycinol: Implications for the design of in vitro experiments and treatment protocols
    • Greene, R. F., Collins, J. M., Jenkins, J. F., Speyer, J. L., and Myers, C. E. Plasma pharmacokinetics of Adriamycin and Adriamycinol: implications for the design of in vitro experiments and treatment protocols. Cancer Res., 43: 3417-3421, 1983.
    • (1983) Cancer Res. , vol.43 , pp. 3417-3421
    • Greene, R.F.1    Collins, J.M.2    Jenkins, J.F.3    Speyer, J.L.4    Myers, C.E.5
  • 60
    • 0023260608 scopus 로고
    • Plasma and cellular Adriamycin concentrations in patients with myeloma treated with ninety-six-hour continuous infusion
    • Speth, P. A., Linssen, P. C., Holdrinet, R. S., and Haanen, C. Plasma and cellular Adriamycin concentrations in patients with myeloma treated with ninety-six-hour continuous infusion. Clin. Pharmacol. Ther., 41: 661-665, 1987.
    • (1987) Clin. Pharmacol. Ther. , vol.41 , pp. 661-665
    • Speth, P.A.1    Linssen, P.C.2    Holdrinet, R.S.3    Haanen, C.4
  • 61
  • 62
    • 0025265751 scopus 로고
    • Etoposide. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic potential in combination chemotherapy of cancer
    • Henwood, J. M., and Brogden, R. N. Etoposide. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic potential in combination chemotherapy of cancer. Drugs, 39: 438-490, 1990.
    • (1990) Drugs , vol.39 , pp. 438-490
    • Henwood, J.M.1    Brogden, R.N.2
  • 63
    • 0029790139 scopus 로고    scopus 로고
    • Phase II study of topotecan in patients with extensive-stage small-cell carcinoma of the lung: An Eastern Cooperative Oncology Group Trial
    • Schiller, J. H., Kim, K., Hutson, P., DeVore, R., Glick, J., Stewart, J., and Johnson, D. Phase II study of topotecan in patients with extensive-stage small-cell carcinoma of the lung: an Eastern Cooperative Oncology Group Trial. J. Clin. Oncol., 14: 2345-2352, 1996.
    • (1996) J. Clin. Oncol. , vol.14 , pp. 2345-2352
    • Schiller, J.H.1    Kim, K.2    Hutson, P.3    DeVore, R.4    Glick, J.5    Stewart, J.6    Johnson, D.7
  • 65
    • 0020082901 scopus 로고
    • A pilot study of high-dose 1-β-D-arabinofuranosylcytosine for acute leukemia and refractory lymphoma: Clinical response and pharmacology
    • Early, A. P., Preisler, H. D., Slocum, H., and Rustum, Y. M. A pilot study of high-dose 1-β-D-arabinofuranosylcytosine for acute leukemia and refractory lymphoma: clinical response and pharmacology. Cancer Res., 42: 1587-1594, 1982.
    • (1982) Cancer Res. , vol.42 , pp. 1587-1594
    • Early, A.P.1    Preisler, H.D.2    Slocum, H.3    Rustum, Y.M.4
  • 67
    • 0018655722 scopus 로고
    • Pharmacokinetics and metabolism of chlorambucil in man: A preliminary report
    • Alberts, D. S., Chang, S. Y., Chen, H. S., Larcom, B. J., and Jones, S. E. Pharmacokinetics and metabolism of chlorambucil in man: a preliminary report. Cancer Treat. Rev., 6: 9-17, 1979.
    • (1979) Cancer Treat. Rev. , vol.6 , pp. 9-17
    • Alberts, D.S.1    Chang, S.Y.2    Chen, H.S.3    Larcom, B.J.4    Jones, S.E.5
  • 70
    • 0027310127 scopus 로고
    • Fludarabine. A review of its pharmacological properties and therapeutic potential in malignancy
    • Ross, S. R., McTavish, D., and Faulds, D. Fludarabine. A review of its pharmacological properties and therapeutic potential in malignancy. Drugs. 45: 737-759, 1993.
    • (1993) Drugs. , vol.45 , pp. 737-759
    • Ross, S.R.1    McTavish, D.2    Faulds, D.3
  • 71
    • 0022888098 scopus 로고
    • High-dose cisplatin in hypertonic saline: Reduced toxicity of a modified dose schedule and correlation with plasma pharmacokinetics. A Northern California Oncology Group Pilot Study in non-small-cell lung cancer
    • Gandara, D. R., DeGregorio, M. W., Wold, H., Wilbur, B. J., Kohler, M., Lawrence, H. J., Deisseroth, A. B., and George, C. B. High-dose cisplatin in hypertonic saline: reduced toxicity of a modified dose schedule and correlation with plasma pharmacokinetics. A Northern California Oncology Group Pilot Study in non-small-cell lung cancer. J. Clin. Oncol., 4: 1787-1793, 1986.
    • (1986) J. Clin. Oncol. , vol.4 , pp. 1787-1793
    • Gandara, D.R.1    DeGregorio, M.W.2    Wold, H.3    Wilbur, B.J.4    Kohler, M.5    Lawrence, H.J.6    Deisseroth, A.B.7    George, C.B.8
  • 73
    • 0022978958 scopus 로고
    • Pharmacokinetics of cis-diamminedichloroplatmum(II) after administration in hypertonic saline
    • Bajorin, D. F., Bosl, G. J., Alcock, N. W., Niedzwiecki, D., Gallina, E., and Shurgot, B. Pharmacokinetics of cis-diamminedichloroplatmum(II) after administration in hypertonic saline. Cancer Res., 46: 5969-5972, 1986.
    • (1986) Cancer Res. , vol.46 , pp. 5969-5972
    • Bajorin, D.F.1    Bosl, G.J.2    Alcock, N.W.3    Niedzwiecki, D.4    Gallina, E.5    Shurgot, B.6
  • 75
    • 0030809817 scopus 로고    scopus 로고
    • In vitro pharmacologic restoration of CFTR-mediated chloride transport with sodium 4-phenylbutyrate in cystic fibrosis epithelial cells containing δ F508-CFTR
    • Rubenstein, R. C., Egan, M. E., and Zeitlin, P. L. In vitro pharmacologic restoration of CFTR-mediated chloride transport with sodium 4-phenylbutyrate in cystic fibrosis epithelial cells containing δ F508-CFTR. J. Clin. Invest., 100: 2457-2465, 1997.
    • (1997) J. Clin. Invest. , vol.100 , pp. 2457-2465
    • Rubenstein, R.C.1    Egan, M.E.2    Zeitlin, P.L.3
  • 76
    • 0028102478 scopus 로고
    • Cleavage of poly(ADP-ribose) polymerase by a protein-ase with properties like ICE
    • Lazebnik, Y. A., Kaufmann, S. H., Desnoyers, S., Poirier, G. G., and Earnshaw, W. C. Cleavage of poly(ADP-ribose) polymerase by a protein-ase with properties like ICE. Nature (Lond.), 371: 346-347, 1994.
    • (1994) Nature (Lond.) , vol.371 , pp. 346-347
    • Lazebnik, Y.A.1    Kaufmann, S.H.2    Desnoyers, S.3    Poirier, G.G.4    Earnshaw, W.C.5
  • 77
    • 0030826338 scopus 로고    scopus 로고
    • FLICE is predominantly expressed as two functionally active isoforms, caspase-8/a and caspase-8/b
    • Scaffidi, C., Medema, J. P., Krammer, P. H., and Peter, M. E. FLICE is predominantly expressed as two functionally active isoforms, caspase-8/a and caspase-8/b. J. Biol. Chem., 272: 26953-26958, 1997.
    • (1997) J. Biol. Chem. , vol.272 , pp. 26953-26958
    • Scaffidi, C.1    Medema, J.P.2    Krammer, P.H.3    Peter, M.E.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.