-
1
-
-
0027180685
-
Selective growth arrest and phenotypic reversion of prostate cancer cells in vitro by nontoxic pharmacological concentrations of phenylacetate
-
Samid, D., Shack, S., and Myers, C. Selective growth arrest and phenotypic reversion of prostate cancer cells in vitro by nontoxic pharmacological concentrations of phenylacetate. J. Clin. Invest., 91: 2288-2295, 1993.
-
(1993)
J. Clin. Invest.
, vol.91
, pp. 2288-2295
-
-
Samid, D.1
Shack, S.2
Myers, C.3
-
2
-
-
0028210550
-
Selective activity of phenylacetate against malignant gliomas: Resemblance to fetal brain damage in phenylketonuria
-
Samid, D., Ram, Z., Hudgins, W. R., Shack, S., Liu, L., Walbridge, S., Oldfield, E. H., and Myers, C. E. Selective activity of phenylacetate against malignant gliomas: resemblance to fetal brain damage in phenylketonuria. Cancer Res., 54: 891-895, 1994.
-
(1994)
Cancer Res.
, vol.54
, pp. 891-895
-
-
Samid, D.1
Ram, Z.2
Hudgins, W.R.3
Shack, S.4
Liu, L.5
Walbridge, S.6
Oldfield, E.H.7
Myers, C.E.8
-
3
-
-
0018148864
-
Control of normal cell differentiation and the phenotypic reversion of malignancy in myeloid leukemia
-
Sacks, L. Control of normal cell differentiation and the phenotypic reversion of malignancy in myeloid leukemia. Nature (Lond.), 274: 535-539, 1978.
-
(1978)
Nature (Lond.)
, vol.274
, pp. 535-539
-
-
Sacks, L.1
-
4
-
-
0026717294
-
The treatment of hairy cell leukemia: An update
-
Golomg, H. M., Ratain, M. J., Mick, R., and Daly, K. The treatment of hairy cell leukemia: an update. Leukemia (Baltimore), 6: 24-27, 1992.
-
(1992)
Leukemia (Baltimore)
, vol.6
, pp. 24-27
-
-
Golomg, H.M.1
Ratain, M.J.2
Mick, R.3
Daly, K.4
-
5
-
-
0022303520
-
Clinical trial on 5-aza-2-deoxycytidine in patients with acute leukemia
-
Momparler, R. L., Rivard, G. E., and Gyger, M. Clinical trial on 5-aza-2-deoxycytidine in patients with acute leukemia. Pharmacol. & Ther., 30: 277-286, 1995.
-
(1995)
Pharmacol. & Ther.
, vol.30
, pp. 277-286
-
-
Momparler, R.L.1
Rivard, G.E.2
Gyger, M.3
-
6
-
-
0026690689
-
Clinical pharmacology of oral all-trans-retinoic acid in patients with acute promyelocytic leukemia
-
Muindi, J. R., Frankel, S. R., Huselton, C., DeGrazia, F., Garland, W. A., Young, C. W., and Warrell, R. P. J. Clinical pharmacology of oral all-trans-retinoic acid in patients with acute promyelocytic leukemia. Cancer Res., 52: 2138-2142, 1992.
-
(1992)
Cancer Res.
, vol.52
, pp. 2138-2142
-
-
Muindi, J.R.1
Frankel, S.R.2
Huselton, C.3
Degrazia, F.4
Garland, W.A.5
Young, C.W.6
Warrell, R.P.J.7
-
7
-
-
0026730287
-
Induction of erythraid differentiation and fetal hemoglobin production in human leukemic cells treated with phenylacetate
-
Samid, D., Yeh, A., and Prasanna, P. Induction of erythraid differentiation and fetal hemoglobin production in human leukemic cells treated with phenylacetate. Blood, 80: 1576-1581, 1992.
-
(1992)
Blood
, vol.80
, pp. 1576-1581
-
-
Samid, D.1
Yeh, A.2
Prasanna, P.3
-
8
-
-
0029937059
-
Vulnerability of multidrug-resistant tumor cells to the aromatic fatty acids phenylacetate and phenylbutyrate
-
Shack, S., Miller, A., Liu, L., Prasanna, P., Thibault, A., and Samid, D. Vulnerability of multidrug-resistant tumor cells to the aromatic fatty acids phenylacetate and phenylbutyrate. Clin. Cancer Res., 2: 865-872, 1996.
-
(1996)
Clin. Cancer Res.
, vol.2
, pp. 865-872
-
-
Shack, S.1
Miller, A.2
Liu, L.3
Prasanna, P.4
Thibault, A.5
Samid, D.6
-
9
-
-
0020955571
-
Biochemical strategy of cancer cells and the design of chemotherapy: G. H. A. memorial lecture
-
Weber, G. Biochemical strategy of cancer cells and the design of chemotherapy: G. H. A. memorial lecture. Cancer Res., 43: 3446-3492, 1983.
-
(1983)
Cancer Res.
, vol.43
, pp. 3446-3492
-
-
Weber, G.1
-
10
-
-
0023959760
-
Glutamine and glucose as energy substrates for ehrlich ascites tumor cells
-
Medina, M. A., Sanchez-Jimenez, F., Markez, F. J., Perez-Rodriguez, J., Quesada, A. R., and Nunez de Castro, I. Glutamine and glucose as energy substrates for ehrlich ascites tumor cells. Biochem. Int., 16: 339-347, 1988.
-
(1988)
Biochem. Int.
, vol.16
, pp. 339-347
-
-
Medina, M.A.1
Sanchez-Jimenez, F.2
Markez, F.J.3
Perez-Rodriguez, J.4
Quesada, A.R.5
Nunez de Castro, I.6
-
11
-
-
0025120211
-
Regulation of the mevalonate pathway
-
Goldstein, J. L., and Brown, M. S. Regulation of the mevalonate pathway. Nature (Lond.), 343: 425-430, 1990.
-
(1990)
Nature (Lond.)
, vol.343
, pp. 425-430
-
-
Goldstein, J.L.1
Brown, M.S.2
-
12
-
-
0026653420
-
The essentials of DNA methylation
-
Bird, A. The essentials of DNA methylation. Cell, 70: 5-8, 1992.
-
(1992)
Cell
, vol.70
, pp. 5-8
-
-
Bird, A.1
-
13
-
-
0028641559
-
Stimulation of adipogenesis in fibroblasts by PPARγ2, a lipid-activated transcription factor
-
Tontonoz, P., Hu, E., and Spiegelman, B. M. Stimulation of adipogenesis in fibroblasts by PPARγ2, a lipid-activated transcription factor. Cell, 79: 1147-1156, 1994.
-
(1994)
Cell
, vol.79
, pp. 1147-1156
-
-
Tontonoz, P.1
Hu, E.2
Spiegelman, B.M.3
-
14
-
-
0029011218
-
The MAPK signalling cascade
-
Seger, R., and Krebs, E. G. The MAPK signalling cascade. FASEB J., 9: 726-735, 1995.
-
(1995)
FASEB J.
, vol.9
, pp. 726-735
-
-
Seger, R.1
Krebs, E.G.2
-
15
-
-
0028931265
-
Principles of CDK regulation
-
Morgan, D. O. Principles of CDK regulation. Nature (Lond.), 374; 131-134, 1995.
-
(1995)
Nature (Lond.)
, vol.374
, pp. 131-134
-
-
Morgan, D.O.1
-
16
-
-
0027717617
-
P21 is a universal inhibitor of cyclin kinases
-
Xiong, Y., Hannon, G. J., Zhang, H., Casso, D., Kobayashi, R., and Beach, D. p21 is a universal inhibitor of cyclin kinases. Nature (Lond.), 366: 701-704, 1993.
-
(1993)
Nature (Lond.)
, vol.366
, pp. 701-704
-
-
Xiong, Y.1
Hannon, G.J.2
Zhang, H.3
Casso, D.4
Kobayashi, R.5
Beach, D.6
-
17
-
-
0027359827
-
WAF1, a potential mediator of p53 tumor suppression
-
El-Deiry, W. S., Tokino, T., Velculescu, T., Levy, D. B., Parsons, R., Trent, J. M., Lin, D., Mercer, W. E., Kinzler, K. W., and Vogelstein, B. WAF1, a potential mediator of p53 tumor suppression. Cell, 75: 817-825, 1993.
-
(1993)
Cell
, vol.75
, pp. 817-825
-
-
El-Deiry, W.S.1
Tokino, T.2
Velculescu, T.3
Levy, D.B.4
Parsons, R.5
Trent, J.M.6
Lin, D.7
Mercer, W.E.8
Kinzler, K.W.9
Vogelstein, B.10
-
20
-
-
0028236846
-
Induction of WAF1/CIP1 by a p53-independent pathway
-
Michieli, P., Chedid, M., Lin, D., Pierce, J. H., Mercer, W. E., and Givol, D. Induction of WAF1/CIP1 by a p53-independent pathway. Cancer Res., 54: 3391-3395, 1994.
-
(1994)
Cancer Res.
, vol.54
, pp. 3391-3395
-
-
Michieli, P.1
Chedid, M.2
Lin, D.3
Pierce, J.H.4
Mercer, W.E.5
Givol, D.6
-
22
-
-
0028963841
-
P53-dependent and independent expression of p21 during cell growth, differentiation and DNA damage
-
Macleod, K. F., Sherry, N., Hannon, G., Beach, D., Tokino, T., Kinzler, K., Vogelstein, B., and Jacks, T. p53-dependent and independent expression of p21 during cell growth, differentiation and DNA damage. Genes Dev., 9: 935-944, 1995.
-
(1995)
Genes Dev.
, vol.9
, pp. 935-944
-
-
Macleod, K.F.1
Sherry, N.2
Hannon, G.3
Beach, D.4
Tokino, T.5
Kinzler, K.6
Vogelstein, B.7
Jacks, T.8
-
23
-
-
0028990221
-
0 and entry into the cell cycle of cells expressing p21Sdi1 antisense RNA
-
0 and entry into the cell cycle of cells expressing p21Sdi1 antisense RNA. Proc. Natl. Acad. Sci. USA, 92: 4352-4356, 1995.
-
(1995)
Proc. Natl. Acad. Sci. USA
, vol.92
, pp. 4352-4356
-
-
Nakanishi, M.1
Adami, G.R.2
Robetorye, R.S.3
Noda, A.4
Venable, S.F.5
Dimitrov, D.6
Pereira-Smith, O.M.7
Smith, J.R.8
-
24
-
-
0028901034
-
Disruption of p53 function sensitizes breast cancer MCF-7 cells to cisplatin and pentoxifylline
-
Fan, S., Smith, M. L., Rivet, D. J., Duba, D., Zhan, Q., Kohn, K. W., Fornace, A. J., Jr., and O'Connor, P. M. Disruption of p53 function sensitizes breast cancer MCF-7 cells to cisplatin and pentoxifylline. Cancer Res., 55: 1649-1654, 1995.
-
(1995)
Cancer Res.
, vol.55
, pp. 1649-1654
-
-
Fan, S.1
Smith, M.L.2
Rivet, D.J.3
Duba, D.4
Zhan, Q.5
Kohn, K.W.6
Fornace Jr., A.J.7
O'Connor, P.M.8
-
26
-
-
0027440552
-
Proliferating cell nuclear antigen and p21 are components of multiple cell cycle kinase complexes
-
Zhang, H., Xiong, Y., and Beach, D. Proliferating cell nuclear antigen and p21 are components of multiple cell cycle kinase complexes. Mol. Biol. Cell, 4: 897-906, 1993.
-
(1993)
Mol. Biol. Cell
, vol.4
, pp. 897-906
-
-
Zhang, H.1
Xiong, Y.2
Beach, D.3
-
27
-
-
0029033861
-
The retinoblastoma protein and cell cycle control
-
Weinberg, R. A. The retinoblastoma protein and cell cycle control. Cell, 81: 323-330, 1995.
-
(1995)
Cell
, vol.81
, pp. 323-330
-
-
Weinberg, R.A.1
-
29
-
-
0026636474
-
Phenylacetate. A novel nontoxic inducer of tumor cell differentiation
-
Samid, D., Shack, S., and Sherman, L. T. Phenylacetate. A novel nontoxic inducer of tumor cell differentiation. Cancer Res., 52: 1988-1992, 1992.
-
(1992)
Cancer Res.
, vol.52
, pp. 1988-1992
-
-
Samid, D.1
Shack, S.2
Sherman, L.T.3
-
30
-
-
0029063579
-
Phase I study of phenyl-acetate administered twice daily to patients with cancer
-
Thibault, A., Samid, D., Cooper, M. R., Figg, W. D., Tompkins, A. C., Patronas, N., Headlee, D. J., Kohler, D. R., Venzon, D. J., and Myers, C. E. Phase I study of phenyl-acetate administered twice daily to patients with cancer. Cancer (Phila.), 75: 2932-2938, 1995.
-
(1995)
Cancer (Phila.)
, vol.75
, pp. 2932-2938
-
-
Thibault, A.1
Samid, D.2
Cooper, M.R.3
Figg, W.D.4
Tompkins, A.C.5
Patronas, N.6
Headlee, D.J.7
Kohler, D.R.8
Venzon, D.J.9
Myers, C.E.10
-
31
-
-
0029916932
-
WAF1 is required for survival of differentiating neuroblastoma cells
-
WAF1 is required for survival of differentiating neuroblastoma cells. Mol. Cell. Biol., 16: 1335-1341, 1996.
-
(1996)
Mol. Cell. Biol.
, vol.16
, pp. 1335-1341
-
-
Poluha, W.1
Poluha, D.K.2
Chang, B.3
Crosbie, N.E.4
Schonhoff, C.M.5
Kilpatrick, D.L.6
Ross, A.H.7
-
33
-
-
0028356521
-
E2F-dependent regulation of human MYC: Trans-activation by cyclins D1 and A overrides tumour suppressor protein functions
-
Oswald, F., Lovec, H., Moray, T., and Lipp, M. E2F-dependent regulation of human MYC: trans-activation by cyclins D1 and A overrides tumour suppressor protein functions. Oncogene, 9: 2029-2036, 1994.
-
(1994)
Oncogene
, vol.9
, pp. 2029-2036
-
-
Oswald, F.1
Lovec, H.2
Moray, T.3
Lipp, M.4
-
34
-
-
0026526437
-
E2F: A link between the Rb tumor suppressor protein and viral oncoproteins
-
Nevins, J. R. E2F: a link between the Rb tumor suppressor protein and viral oncoproteins. Science (Washington DC), 258: 424-429, 1992.
-
(1992)
Science (Washington DC)
, vol.258
, pp. 424-429
-
-
Nevins, J.R.1
-
35
-
-
0028267869
-
DRTF1/E2F: An expanding family of heterodimeric transcription factors implicated in cell cycle control
-
LaThangue, N. B. DRTF1/E2F: an expanding family of heterodimeric transcription factors implicated in cell cycle control. Trends. Biochem. Sci., 19: 108-114, 1994.
-
(1994)
Trends. Biochem. Sci.
, vol.19
, pp. 108-114
-
-
Lathangue, N.B.1
-
36
-
-
0028927179
-
P53, cell cycle control and apoptosis: Implications for cancer
-
Kastan, M. B., Canman, C. E., and Leonard, C. J. p53, cell cycle control and apoptosis: implications for cancer. Cancer Metastasis Rev., 14: 3-15, 1995.
-
(1995)
Cancer Metastasis Rev.
, vol.14
, pp. 3-15
-
-
Kastan, M.B.1
Canman, C.E.2
Leonard, C.J.3
-
37
-
-
10544231657
-
A Phase II trial of phenylacetic acid for the recurrent malignant glioma, preliminary report of the North American brain tumor consortium
-
Prados, M. D., Spence, A., Schold, C., Mehta, M., Kuhn, J., Rector, D., Chang, S., and Gilbert, M. A Phase II trial of phenylacetic acid for the recurrent malignant glioma, preliminary report of the North American brain tumor consortium. Proc. Am. Soc. Clin. Oncol. Annu. Meet., 288: 156, 1996.
-
(1996)
Proc. Am. Soc. Clin. Oncol. Annu. Meet.
, vol.288
, pp. 156
-
-
Prados, M.D.1
Spence, A.2
Schold, C.3
Mehta, M.4
Kuhn, J.5
Rector, D.6
Chang, S.7
Gilbert, M.8
-
38
-
-
0028123442
-
The p53 gene and protein in human brain tumors
-
Louis, D. N. The p53 gene and protein in human brain tumors. J. Neuropathol. & Exp. Neural., 53: 11-21, 1994.
-
(1994)
J. Neuropathol. & Exp. Neural.
, vol.53
, pp. 11-21
-
-
Louis, D.N.1
-
39
-
-
0028175707
-
P53 mutation, expression, and DMA ploidy in evolving gliomas: Evidence for two pathways of progression
-
van Meyel, D. J., Ramsay, D. A., Casson, A. G., Keeney, M., Chambers, A. F., and Cairncross, J. G. p53 mutation, expression, and DMA ploidy in evolving gliomas: evidence for two pathways of progression. J. Natl. Cancer Inst., 86: 1011-1017, 1994.
-
(1994)
J. Natl. Cancer Inst.
, vol.86
, pp. 1011-1017
-
-
Van Meyel, D.J.1
Ramsay, D.A.2
Casson, A.G.3
Keeney, M.4
Chambers, A.F.5
Cairncross, J.G.6
-
40
-
-
0028117269
-
Analysis of the p53 gene and its expression in human glioblastoma cells
-
Van Meir, E. G., Kikuchi, T., Tada, M., Li, H., Diserens, A. C., Wojcik, B. E., Huang, H. J., Friedmann, T., de Tribolet, N., and Cavenee, W. K. Analysis of the p53 gene and its expression in human glioblastoma cells. Cancer Res., 54: 649-652, 1994.
-
(1994)
Cancer Res.
, vol.54
, pp. 649-652
-
-
Van Meir, E.G.1
Kikuchi, T.2
Tada, M.3
Li, H.4
Diserens, A.C.5
Wojcik, B.E.6
Huang, H.J.7
Friedmann, T.8
De Tribolet, N.9
Cavenee, W.K.10
-
41
-
-
0027331499
-
P53 protein accumulation and gene mutations in human glioma cell lines
-
Anker, L., Ohgaki, H., Ludeke, B. I., Herrmann, H. D., Kleihues, P., and Westphal, M. p53 protein accumulation and gene mutations in human glioma cell lines. Int. J. Cancer, 55: 982-987, 1993.
-
(1993)
Int. J. Cancer
, vol.55
, pp. 982-987
-
-
Anker, L.1
Ohgaki, H.2
Ludeke, B.I.3
Herrmann, H.D.4
Kleihues, P.5
Westphal, M.6
|