Characterization of the cerebroprotective efficacy of the competitive NDMA receptor antagonist CGP40116 in a rat model of focal cerebral ischemia: An in vivo magnetic resonance imaging study

Journal of Cerebral Blood Flow and Metabolism

Volumn 13, Issue 4, 1993, Pages 595-602

  Sauer, Dirk ^a   Allegrini, Peter R ^a   Cosenti, Alexandra ^a   Pataki, Alexander ^a   Amacker, Hugo ^a   Fagg, Graham E ^a  

^a CIBA GEIGY LTD   (Switzerland)

Author keywords

CGP 40116; Focal cerebral ischemia; Magnetic resonance imaging; Neuroprotection; NMDA antagonists; Rat

Indexed keywords

2 AMINO 4 METHYL 5 PHOSPHONO 3 PENTENOIC ACID; 4 (3 PHOSPHONOALLYL) 2 PIPERAZINECARBOXYLIC ACID; 4 PHOSPHONOMETHYLPIPECOLIC ACID; DIZOCILPINE; N METHYL DEXTRO ASPARTIC ACID RECEPTOR;

ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN EDEMA; BRAIN INFARCTION; BRAIN ISCHEMIA; BRAIN PROTECTION; CONTROLLED STUDY; DOSE RESPONSE; DRUG EFFICACY; DRUG POTENCY; IMAGE ANALYSIS; INTRAVENOUS DRUG ADMINISTRATION; MALE; MIDDLE CEREBRAL ARTERY OCCLUSION; NEUROPATHOLOGY; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; PRIORITY JOURNAL; RAT;

2-AMINO-5-PHOSPHONOVALERATE; ANIMAL; BINDING, COMPETITIVE; BRAIN; BRAIN EDEMA; BRAIN ISCHEMIA; CATS; COMPARATIVE STUDY; MAGNETIC RESONANCE IMAGING; RATS; RECEPTORS, N-METHYL-D-ASPARTATE; TIME FACTORS;

EID: 0027310151     PISSN: 0271678X     EISSN: None     Source Type: Journal    
DOI: 10.1038/jcbfm.1993.77     Document Type: Article

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