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Volumn 38, Issue 6, 2000, Pages 469-481

Activation of mitogen-activated protein kinases in different models of pancreatic acinar cell damage

Author keywords

Apoptosis; Bax; Bcl 2; Cholecystokinin; Mitogen activated protein kinases; p53; Pancreatic acinar cells; Ultraviolet

Indexed keywords

2 [1 (3 DIMETHYLAMINOPROPYL) 3 INDOLYL] 3 (3 INDOLYL)MALEIMIDE; ACETYLCYSTEINE; ACRIDINE ORANGE; CHOLECYSTOKININ; ETHIDIUM BROMIDE; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN BAK; PROTEIN BCL 2; PROTEIN KINASE C INHIBITOR; PROTEIN P53; STRESS ACTIVATED PROTEIN KINASE;

EID: 0033947758     PISSN: 00442771     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-2000-14885     Document Type: Article
Times cited : (7)

References (48)
  • 1
    • 0002785313 scopus 로고    scopus 로고
    • The pathogenesis and pathophysiology of acute pancreatitis
    • Steer ML. The pathogenesis and pathophysiology of acute pancreatitis. J Physiol Pharmacol 1998; 49 (suppl. 2): 47-59
    • (1998) J Physiol Pharmacol , vol.49 , Issue.SUPPL. 2 , pp. 47-59
    • Steer, M.L.1
  • 2
    • 0028783295 scopus 로고
    • Relationship between severity, necrosis, and apoptosis in five models of experimental acute pancreatitis
    • Kaiser AM, Saluja AK, Sengupta A, Saluja M, Steer ML. Relationship between severity, necrosis, and apoptosis in five models of experimental acute pancreatitis. Am J Physiol 1995; 269: C1295-C1304
    • (1995) Am J Physiol , vol.269
    • Kaiser, A.M.1    Saluja, A.K.2    Sengupta, A.3    Saluja, M.4    Steer, M.L.5
  • 4
    • 0030025675 scopus 로고    scopus 로고
    • Mechanism of cell death after pancreatic duct obstruction in the opossum and the rat
    • Gukovskaya AS, Perkins P, Zaninovic V et al. Mechanism of cell death after pancreatic duct obstruction in the opossum and the rat. Gastroenterology 1996; 110: 875-84
    • (1996) Gastroenterology , vol.110 , pp. 875-884
    • Gukovskaya, A.S.1    Perkins, P.2    Zaninovic, V.3
  • 5
    • 0029841658 scopus 로고    scopus 로고
    • The role of neutrophils and platelet-activating factor in mediating experimental pancreatitis
    • Sandoval D, Gukovskaya A, Reavey P et al. The role of neutrophils and platelet-activating factor in mediating experimental pancreatitis. Gastroenterology 1996; 111: 1081-91
    • (1996) Gastroenterology , vol.111 , pp. 1081-1091
    • Sandoval, D.1    Gukovskaya, A.2    Reavey, P.3
  • 6
    • 0029993964 scopus 로고    scopus 로고
    • Lipopolisaccharide induced apoptosis of rat pancreatic acinar cells
    • Laine VJO, Nyman KM, Peuravuori HJ et al. Lipopolisaccharide induced apoptosis of rat pancreatic acinar cells. Gut 1996; 38: 747-52
    • (1996) Gut , vol.38 , pp. 747-752
    • Laine, V.J.O.1    Nyman, K.M.2    Peuravuori, H.J.3
  • 7
    • 0031036950 scopus 로고    scopus 로고
    • Role of apoptosis in duct obstruction-induced pancreatic involution in rats
    • Doi R, Wada M. Hosotani R et al. Role of apoptosis in duct obstruction-induced pancreatic involution in rats. Pancreas 1997; 14: 39-46
    • (1997) Pancreas , vol.14 , pp. 39-46
    • Doi, R.1    Wada, M.2    Hosotani, R.3
  • 9
    • 0030800825 scopus 로고    scopus 로고
    • Ischemia-reperfusion injury on the pancreas in rats: Identification of acinar cell apoptosis
    • Fujimoto K, Hosotani R, Wada M et al. Ischemia-reperfusion injury on the pancreas in rats: identification of acinar cell apoptosis. J Surg Res 1997; 71: 127-36
    • (1997) J Surg Res , vol.71 , pp. 127-136
    • Fujimoto, K.1    Hosotani, R.2    Wada, M.3
  • 10
    • 0031916838 scopus 로고    scopus 로고
    • Endogenous glucocorticoids decrease the acinar cell sensitivity to apoptosis during cerulein pancreatitis in rats
    • Kimura K, Shimosegawa T, Sasano H et al. Endogenous glucocorticoids decrease the acinar cell sensitivity to apoptosis during cerulein pancreatitis in rats. Gastroenterology 1998; 114: 372-81
    • (1998) Gastroenterology , vol.114 , pp. 372-381
    • Kimura, K.1    Shimosegawa, T.2    Sasano, H.3
  • 11
    • 0031946284 scopus 로고    scopus 로고
    • The pancreatitis-associated protein is induced by free radicals in AR4-2J cells and confers cell resistance to apoptosis
    • Ortiz EM, Dusetti NJ, Vasseur S et al. The pancreatitis-associated protein is induced by free radicals in AR4-2J cells and confers cell resistance to apoptosis. Gastroenterology 1998; 114: 808-16
    • (1998) Gastroenterology , vol.114 , pp. 808-816
    • Ortiz, E.M.1    Dusetti, N.J.2    Vasseur, S.3
  • 12
    • 0028000213 scopus 로고
    • The mitogen activated protein kinase signal transduction pathway: From the cell surface to the nucleus
    • Guan K-L. The mitogen activated protein kinase signal transduction pathway: from the cell surface to the nucleus. Cell Signal 1994; 6: 581-9
    • (1994) Cell Signal , vol.6 , pp. 581-589
    • Guan, K.-L.1
  • 13
    • 0028926263 scopus 로고
    • Parallel signal processing among mammalian MAPKs
    • Cano E, Mahadevan LC. Parallel signal processing among mammalian MAPKs. Trends Biochem Sci 1995; 20: 117-22
    • (1995) Trends Biochem Sci , vol.20 , pp. 117-122
    • Cano, E.1    Mahadevan, L.C.2
  • 14
    • 0029900434 scopus 로고    scopus 로고
    • G protein-coupled receptors and signaling pathways regulating growth responses
    • Post GR, Brown JH. G protein-coupled receptors and signaling pathways regulating growth responses. FASEB J 1996; 10: 741-9
    • (1996) FASEB J , vol.10 , pp. 741-749
    • Post, G.R.1    Brown, J.H.2
  • 15
    • 0029011218 scopus 로고
    • The MAPK signaling cascade
    • Seger R, Krebs EG. The MAPK signaling cascade. FEBS J 1995; 9: 726-35
    • (1995) FEBS J , vol.9 , pp. 726-735
    • Seger, R.1    Krebs, E.G.2
  • 16
    • 0029025036 scopus 로고
    • The regulation of tyrosine kinase signaling pathways by growth factor and G-protein-coupled receptors
    • Malarkey K, Belham CM, Paul A et al. The regulation of tyrosine kinase signaling pathways by growth factor and G-protein-coupled receptors. Biochem J 1995;309: 361-75
    • (1995) Biochem J , vol.309 , pp. 361-375
    • Malarkey, K.1    Belham, C.M.2    Paul, A.3
  • 17
    • 0028880006 scopus 로고
    • Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis
    • Xia Z, Dickens M, Raingeaud J, Davis R, Greenberg ME. Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis. Science 1995; 270: 1326-31
    • (1995) Science , vol.270 , pp. 1326-1331
    • Xia, Z.1    Dickens, M.2    Raingeaud, J.3    Davis, R.4    Greenberg, M.E.5
  • 18
    • 0028156378 scopus 로고
    • Cholecystokinin rapidly activates mitogen-activated protein kinase in rat pancreatic acini
    • Duan RD, Williams JA. Cholecystokinin rapidly activates mitogen-activated protein kinase in rat pancreatic acini. Am J Physiol 1994; 267: G401-G408
    • (1994) Am J Physiol , vol.267
    • Duan, R.D.1    Williams, J.A.2
  • 19
    • 0028835482 scopus 로고
    • Activation of MAP kinase kinase (MEK) and Ras by cholecystokinin in rat pancreatic acini
    • Duan R-D, Zheng C-F, Guan K-L, Williams JA. Activation of MAP kinase kinase (MEK) and Ras by cholecystokinin in rat pancreatic acini. Am J Physiol 1995; 268: G1060-G1065
    • (1995) Am J Physiol , vol.268
    • Duan, R.-D.1    Zheng, C.-F.2    Guan, K.-L.3    Williams, J.A.4
  • 20
    • 0029864407 scopus 로고    scopus 로고
    • Jun kinases are rapidly activated by cholecystokinin in rat pancreas both in vitro and in vivo
    • Dahrowski A, Grady T, Logsdon CD, Williams JA. Jun kinases are rapidly activated by cholecystokinin in rat pancreas both in vitro and in vivo. J Biol Chem 1996; 271: 5686-90
    • (1996) J Biol Chem , vol.271 , pp. 5686-5690
    • Dahrowski, A.1    Grady, T.2    Logsdon, C.D.3    Williams, J.A.4
  • 21
    • 0029864557 scopus 로고    scopus 로고
    • Cholecystokinin stimulates formation of Shc-Grh2 complex in rat pancreatic acinar cells through a protein kinase C-dependent mechanism
    • Dabrowski A, VanderKuur JA, Carler-Su C, Williams JA. Cholecystokinin stimulates formation of Shc-Grh2 complex in rat pancreatic acinar cells through a protein kinase C-dependent mechanism. J Biol Chem 1996; 271: 27125-9
    • (1996) J Biol Chem , vol.271 , pp. 27125-27129
    • Dabrowski, A.1    Vanderkuur, J.A.2    Carler-Su, C.3    Williams, J.A.4
  • 22
    • 0030720786 scopus 로고    scopus 로고
    • Cholecystokinin and egf activate mapk cascade by different mechanisms in rat pancreatic acinar cells
    • Dabrowski A, Groblewski GE, Schäfer C, Guan K-L, Williams JA. Cholecystokinin and EGF activate MAPK cascade by different mechanisms in rat pancreatic acinar cells. Am J Physiol 1997; 273: C1472-C1479
    • (1997) Am J Physiol , vol.273
    • Dabrowski, A.1    Groblewski, G.E.2    Schäfer, C.3    Guan, K.-L.4    Williams, J.A.5
  • 23
    • 0031536705 scopus 로고    scopus 로고
    • Novel kinase signaling cascades in pancreatic acinar cells
    • Williams JA, Dabrowski A, Logsdon CD. Novel kinase signaling cascades in pancreatic acinar cells. News Physiol Sci 1997; 12: 117-21
    • (1997) News Physiol Sci , vol.12 , pp. 117-121
    • Williams, J.A.1    Dabrowski, A.2    Logsdon, C.D.3
  • 24
    • 0032508660 scopus 로고    scopus 로고
    • A role for the p38 mitogen-activated protein kinase/Hsp 27 pathway in cholecystokinin-induced changes in the actin cytoskeleton in rat pancreatic acini
    • Schäfer C, Ross SE, Bragado MJ et al. A role for the p38 mitogen-activated protein kinase/Hsp 27 pathway in cholecystokinin-induced changes in the actin cytoskeleton in rat pancreatic acini. J Biol Chem 1998; 273: 24173-80
    • (1998) J Biol Chem , vol.273 , pp. 24173-24180
    • Schäfer, C.1    Ross, S.E.2    Bragado, M.J.3
  • 25
    • 0032546791 scopus 로고    scopus 로고
    • Ultraviolet radiation triggers the ribotoxic stress response in mammalian cells
    • Iordanov MS, Pribnow D, Magun JL et al. Ultraviolet radiation triggers the ribotoxic stress response in mammalian cells. J Biol Chem 1998; 273: 15794-803
    • (1998) J Biol Chem , vol.273 , pp. 15794-15803
    • Iordanov, M.S.1    Pribnow, D.2    Magun, J.L.3
  • 26
    • 0033529263 scopus 로고    scopus 로고
    • Nuclear and cell membrane effects contribute independently to the induction of apoptosis in human cells exposed to UVB radiation
    • Kulms D, Poppelmann B, Yarosh D et al. Nuclear and cell membrane effects contribute independently to the induction of apoptosis in human cells exposed to UVB radiation. Proc Natl Acad Sci USA 1999; 96: 7974-9
    • (1999) Proc Natl Acad Sci USA , vol.96 , pp. 7974-7979
    • Kulms, D.1    Poppelmann, B.2    Yarosh, D.3
  • 27
    • 0032897552 scopus 로고    scopus 로고
    • Activation of p38 mitogen-activated protein kinase and caspases in UVB-induced apoptosis of human keratinocyte HaCaT cells
    • Shimizu H, Banno Y, Sumi N et al. Activation of p38 mitogen-activated protein kinase and caspases in UVB-induced apoptosis of human keratinocyte HaCaT cells. J Invest Dermatol 1999; 112: 769-74
    • (1999) J Invest Dermatol , vol.112 , pp. 769-774
    • Shimizu, H.1    Banno, Y.2    Sumi, N.3
  • 28
    • 0033617288 scopus 로고    scopus 로고
    • P38 kinase mediates UV-induced phosphorylation of p53 protein at serine 389
    • Huang C, Ma W-Y, Maxiner A, Sun Y, Dong Z. P38 kinase mediates UV-induced phosphorylation of p53 protein at serine 389. J Biol Chem 1999; 274: 12229-35
    • (1999) J Biol Chem , vol.274 , pp. 12229-12235
    • Huang, C.1    Ma, W.-Y.2    Maxiner, A.3    Sun, Y.4    Dong, Z.5
  • 29
    • 0018033383 scopus 로고
    • Action of secret-agogues on a new preparation of functionally intact, isolated pancreatic acini
    • Williams JA, Korc M, Dormer RL. Action of secret-agogues on a new preparation of functionally intact, isolated pancreatic acini. Am J Physiol 1978; 253: E517-E524
    • (1978) Am J Physiol , vol.253
    • Williams, J.A.1    Korc, M.2    Dormer, R.L.3
  • 31
    • 0002230857 scopus 로고
    • Morphological and biochemical assays of apoptosis
    • Duke RC, Cohen JJ. Morphological and biochemical assays of apoptosis. Curr Prot Immunol (suppl. 3) 1992; 17: 1-16
    • (1992) Curr Prot Immunol (Suppl. 3) , vol.17 , pp. 1-16
    • Duke, R.C.1    Cohen, J.J.2
  • 32
    • 0028881770 scopus 로고
    • UV irradiation and heat shock mediate JNK activation via alternative pathways
    • Adler V, Schaffer A, Kim J, Dolan L, Ronai Z. UV irradiation and heat shock mediate JNK activation via alternative pathways. J Biol Chem 1995; 270: 26071-7
    • (1995) J Biol Chem , vol.270 , pp. 26071-26077
    • Adler, V.1    Schaffer, A.2    Kim, J.3    Dolan, L.4    Ronai, Z.5
  • 34
    • 0029955623 scopus 로고    scopus 로고
    • Reactive oxygen species mediate cytokine activation of c-Jun NH2-terminal kinases
    • Lo YYC, Wong JMS, Cruz TF. Reactive oxygen species mediate cytokine activation of c-Jun NH2-terminal kinases. J Biol Chem 1996; 271: 15703-7
    • (1996) J Biol Chem , vol.271 , pp. 15703-15707
    • Lo, Y.Y.C.1    Wong, J.M.S.2    Cruz, T.F.3
  • 35
    • 0032575688 scopus 로고    scopus 로고
    • The Bcl-2 protein family: Arbiters of cell survival
    • Adams JM, Gory S. The Bcl-2 protein family: arbiters of cell survival. Science 1998; 281: 1322-6
    • (1998) Science , vol.281 , pp. 1322-1326
    • Adams, J.M.1    Gory, S.2
  • 36
    • 0032575705 scopus 로고    scopus 로고
    • A matter of life and cell death
    • Evan G, Litlewood T. A matter of life and cell death. Science 1998; 281: 1317-21
    • (1998) Science , vol.281 , pp. 1317-1321
    • Evan, G.1    Litlewood, T.2
  • 37
    • 0029731366 scopus 로고    scopus 로고
    • Redifferentiation and apoptosis of pancreatic cells during acute pancreatitis
    • Iovanna JL. Redifferentiation and apoptosis of pancreatic cells during acute pancreatitis. Int J Pancreatol 1996; 20: 77-84
    • (1996) Int J Pancreatol , vol.20 , pp. 77-84
    • Iovanna, J.L.1
  • 38
    • 0030820039 scopus 로고    scopus 로고
    • Role of neutrophils in cerulein-induced pancreatitis in rats: Possible involvement of apoptosis
    • Fujimoto K, Hosotani R, Doi R et al. Role of neutrophils in cerulein-induced pancreatitis in rats: possible involvement of apoptosis. Digestion 1997; 58: 421-30
    • (1997) Digestion , vol.58 , pp. 421-430
    • Fujimoto, K.1    Hosotani, R.2    Doi, R.3
  • 39
    • 0031817371 scopus 로고    scopus 로고
    • Low doses of lipopolysaccharide upregulate acinar cell apoptosis in cerulein pancreatitis
    • Kimura K, Shimosegawa T, Abe R et al. Low doses of lipopolysaccharide upregulate acinar cell apoptosis in cerulein pancreatitis. Pancreas 1998; 17: 120-6
    • (1998) Pancreas , vol.17 , pp. 120-126
    • Kimura, K.1    Shimosegawa, T.2    Abe, R.3
  • 40
    • 0033598155 scopus 로고    scopus 로고
    • Extranuclear apoptosis: The role of the cytoplasm in the execution phase
    • Mills JC, Stone NL, Pittman RN. Extranuclear apoptosis: The role of the cytoplasm in the execution phase. J Cell Biol 1999; 146: 703-7
    • (1999) J Cell Biol , vol.146 , pp. 703-707
    • Mills, J.C.1    Stone, N.L.2    Pittman, R.N.3
  • 41
    • 0033961249 scopus 로고    scopus 로고
    • Caspase 3 cleavage of the Ste20-related kinase SLK releases and activates an apoptosis-inducing kinase domain and an actin-disassembling region
    • Sahourin LA, Seale P, Wagner J, Rudnicki MA. Caspase 3 cleavage of the Ste20-related kinase SLK releases and activates an apoptosis-inducing kinase domain and an actin-disassembling region. Mol Cell Biol 2000; 20: 684-96
    • (2000) Mol Cell Biol , vol.20 , pp. 684-696
    • Sahourin, L.A.1    Seale, P.2    Wagner, J.3    Rudnicki, M.A.4
  • 42
    • 0033527063 scopus 로고    scopus 로고
    • Involvement of caspase 3-activated DNase in internucleosomal DNA cleavage induced by diverse apoptotic stimuli
    • McIlroy D, Sakahira H, Talanian RV, Nagata S. Involvement of caspase 3-activated DNase in internucleosomal DNA cleavage induced by diverse apoptotic stimuli. Oncogene 1999; 18: 4401-8
    • (1999) Oncogene , vol.18 , pp. 4401-4408
    • McIlroy, D.1    Sakahira, H.2    Talanian, R.V.3    Nagata, S.4
  • 43
    • 0030868999 scopus 로고    scopus 로고
    • Ultraviolet radiation-induced apoptosis is mediated by activation of CD-95 (Fas/APO-1)
    • Rehetulla A, Hamilton CA, Chinnaiyan AM, Dixit VM. Ultraviolet radiation-induced apoptosis is mediated by activation of CD-95 (Fas/APO-1). J Biol Chem 1997; 272: 25783-6
    • (1997) J Biol Chem , vol.272 , pp. 25783-25786
    • Rehetulla, A.1    Hamilton, C.A.2    Chinnaiyan, A.M.3    Dixit, V.M.4
  • 44
    • 0033052701 scopus 로고    scopus 로고
    • Supra-physiologic concentrations of cerulein induce apoptosis in the rat pancreatic acinar cell line AR4-2J
    • Sata N, Klonowski-Stumpe H, Han B et al. Supra-physiologic concentrations of cerulein induce apoptosis in the rat pancreatic acinar cell line AR4-2J. Pancreas 1999; 19: 76-82
    • (1999) Pancreas , vol.19 , pp. 76-82
    • Sata, N.1    Klonowski-Stumpe, H.2    Han, B.3
  • 45
    • 0032897568 scopus 로고    scopus 로고
    • Mechanisms of hepatic toxicity. V. Necraptosis and the mitochondrial permeability transition: Shared pathways to necrosis and apoptosis
    • Lemasters JJ. Mechanisms of hepatic toxicity. V. Necraptosis and the mitochondrial permeability transition: shared pathways to necrosis and apoptosis. Am J Physiol 1999; 276: G1-G6
    • (1999) Am J Physiol , vol.276
    • Lemasters, J.J.1
  • 46
    • 0028917954 scopus 로고
    • Regulation of Ras-mediated signalling: More than one way to skin a cat
    • Burgering BM, Bos JL. Regulation of Ras-mediated signalling: more than one way to skin a cat. Trends Biochem Sci 1995; 20: 18-22
    • (1995) Trends Biochem Sci , vol.20 , pp. 18-22
    • Burgering, B.M.1    Bos, J.L.2
  • 47
    • 0033022633 scopus 로고    scopus 로고
    • Translocation of protein kinase Cepsilon and protein kinase cdelta to membrane is required for ultraviolet B-induced activation of mitogen-activated protein kinase and apoptosis
    • Chen N, Ma Wy, Huang C, Dong Z. Translocation of protein kinase Cepsilon and protein kinase Cdelta to membrane is required for ultraviolet B-induced activation of mitogen-activated protein kinase and apoptosis. J Biol Chem 1999; 274: 15389-94
    • (1999) J Biol Chem , vol.274 , pp. 15389-15394
    • Chen, N.1    Ma, W.2    Huang, C.3    Dong, Z.4
  • 48
    • 0033520375 scopus 로고    scopus 로고
    • 2-terminal kinase (JNK1) activation by ultrafiolet-B radiation and by oxidative stressors
    • 2-terminal kinase (JNK1) activation by ultrafiolet-B radiation and by oxidative stressors. J Biol Chem 1999; 274: 25801-6
    • (1999) J Biol Chem , vol.274 , pp. 25801-25806
    • Iordanov, M.S.1    Magun, B.E.2


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