Cytotoxicity of peroxynitrite in rat pancreatic acinar AR4-2J cells

Pancreas

Volumn 15, Issue 3, 1997, Pages 278-284

  Sata, Naohiro ^a,b   Klonowski Stumpe, Hanne ^a,b   Han, Bing ^a,b   Häussinger, Dieter ^a,b   Niederau, Claus ^a,b  

^a HEINRICH HEINE UNIVERSITY   (Germany)

^b Kikkoman General Hospital   (Japan)

Author keywords

Apoptosis; AR4 2J; Ebselen; Glutathione; Peroxynitrite; Wild type P53

Indexed keywords

CALCIUM; DNA FRAGMENT; EBSELEN; GLUTATHIONE; PEROXYNITRITE; PROTEIN P53;

ACINAR CELL; ANIMAL CELL; APOPTOSIS; ARTICLE; CELL DEATH; CONTROLLED STUDY; CYTOTOXICITY; DNA DAMAGE; NONHUMAN; PRIORITY JOURNAL; RAT;

EID: 0030731847     PISSN: 08853177     EISSN: None     Source Type: Journal    
DOI: 10.1097/00006676-199710000-00010     Document Type: Article

References (57)

1. Blough NV, Zafiriou OC. Reaction of Superoxide with nitric oxide to form peroxynitrite in alkaline aqueous solution. Inorg Chem 1985;24:3502-4.
2. Saran M, Michel C, Bors W. Reaction of NO and O2~. Implication for the action of endothelium-derived relaxing factor. Free Radie Res 1990;10:221-6.
3. Huie RE, Padmaja S. The reaction rate of nitric oxide with superoxide. Free Radie Res 1993;18:195-9.
4. Beckman JS, Beckman TW, Chen J, Marshall PA, Freeman BA. Apparent hydroxyl radical production by peroxynitrite: implications for endothelial injury from nitric oxide and Superoxide. Proc NatlAcadSci USA 1990;87:1620-4.
5. Lipton SA, Choi YB, Pan ZH, et al. A redox-based mechanism for the neutroprotective and neutrodestructive effects of nitric oxide and related nitrosocompounds. Nature (London) 1993:364:626-32.
6. Estevez AG, Radi R, Barbeito L, Shin JT, Thompson JA, Beckman JS. Peroxynitrite-induced cytotoxicity in PC12 cells: evidence for an apoptotic mechanism differentially modulated by neurotrophic factors. J Neurochem 1995:65:1543-50.
7. Bonfoco E, Krainc D, Ankarcrona M, Nicotera P, Lipton SA. Apoptosis and necrosis: two distinct events induced, respectively, by mild and intense insults with N-methyl-D-aspartate or nitric oxide/superoxide in cortical cell cultures. Proc Natl Acad USA 1995:92:7162-6.
8. Gunasekar PG, Kanthasamy AG, Borowitz JL, Isom GE. NMDA receptor activation produces concurrent generation of nitric oxide and reactive oxygen species: implication for cell death. J Neurochem 1995:65:2016-21.
9. Ischiropoulos H, Duran D, Horwitz J. Peroxynitrite-mediated inhibition of DOPA synthesis in PC12 cells. J Neurochem 1995;65: 2366-72.
10. Packer MA, Miesel R, Murphy MP. Exposure to the parkinsonian neurotoxin l-methyl-4-phenylpyridium (MPP+) and nitric oxide simultaneously causes cyclosporin A-sensitive mitochondria! calcium efflux and depolarisation. Biochem Phannacol 1996;51:26773.
11. Hogg N, Darley-Usmar VM, Graham A, Moncada S. Peroxynitrite and atherosclerosis. Biochem Soc Trans 1993:21:358-62.
12. Graham A, Hogg N, Kalyanaraman B, O'Leary V, Darley-Usmar V, Moncada S. Peroxynitrite modification of low-density lipoprotein leads to recognition by the macrophage scavenger receptor. FEBS Lett 1993:330:181-5.
13. Phelps D, Ferro TJ, Higgins PJ, Shankar R, Parker DM, Johnson A. TNF-oc induces peroxynitrite-mediated depletion of lung endothelial glutathione via protein kinase C. Am J Physiol 1995;269: L551-9.
14. Robbins CG, Davis JM, Merritt TA, et al. Combined effects of nitric oxide and hyperoxia on surfactant function and pulmonary inflammation. Am J Physiol 1995;269:L545-50.
15. Seo HG, Takata I, Nakamura M, et al. Induction of nitric oxide synthase and concomitant suppression of Superoxide dismutases in experimental colitis in rats. Arch Biochem Biophys 1995:324:41-7.
16. Lamarque D, Whittle BJR. Involvement of Superoxide and xanthine oxidase in neutrophil-independent rat gastric damage induced by NO donors. BrJ Phannacol 1995; 116:1843-8.
17. Lin K, Xue J, Nomen M, Spur B, Wong PYK. Peroxynitriteinduced apoptosis in HL-60 cells. J Biol Chem 1995:270:1648790.
18. Salgo MG, Squadrito GL, Pryor WA. Peroxynitrite causes apoptosis in rat thymocytes. Biochem Biophys Res Commun 1995;215: 1111-8.
19. Sanfey H, Bulkley G, Cameron JL. The role of oxygen derived free radicals in the pathogenesis of acute pancreatitis. Ann Stirg 1984; 200:405-13.
20. Schoenberg MH, Bucher M, Beger HG. Oxygen free radicals in acute pancreatitis of the rat. Gut 1990;31:1138.
21. Kishimoto W, Nakao A, Nakano M, Takahashi A, Inaba H, Takagi H. Detection of Superoxide free radicals in rats with acute pancreatitis. Pancreas 1995;! 1:122-6.
22. Niederau C, Schulz HU, Klonowski H. Lazaroids protect isolated rat pancreatic acinar cells against damage induced by free radicals. Pancreas 1995;! 1:107-21.
23. Konturek SJ, Szlachcic A, Dembinski A, Warzecha Z, Jaworek J, Stachura J. Nitric oxide in pancreatic secretion and hormoneinduced pancreatitis in rats. Int J Pancreatol I994;15:19-28.
24. Satih A, Shimosegavva T, Abe T, et al. Role of nitric oxide in the pancreatic blood flow response to caerulein. Pancreas 1994;9: 574-9.
25. Wrenn RW, Currie MG, Herman LE. Nitric oxide participates in the regulation of pancreatic acinar cell secretion. Life Sci 1994;55: 511-8.
26. Jessop NW, Hay RJ. Characteristic of two rat pancreatic exocrine cell lines derived from transplantable tumors. In Vitro 1980; 16: 212A (abstr.).
27. Logsdon CD. Glucocorticoids increase cholecystokinin receptors and amylase secretion in pancreatic acinar AR4-2J cells. / Biol Chem 1986;261:2096-101.
28. Seva C, De Vries L, Scemama JL, et al. Gastrin modulates growth of a rat acinar pancreatic cell line: receptor analysis and signal transduction. Digestion 1990;46 (Suppl 2):166-9.
29. Delvaux M, Bastie MJ, Chentoufi J, Rivet A, Vaysse N. Na+/H+ exchange in AR4-2J cells: stimulation by growth factors and pancreatic secretagogues. Digestion 1990;46 (Suppl 2):156-61.
30. Tsuzuki S, Kondo A, Fushiki T, Sugimoto E. Monitor peptide gene expression is increased by exogenous CCK in the rat pancreas and in a rat pancreatic acinar cell line (AR4-2J). FEBS Lett 1992;307: 386-8.
31. Scemama JL, De Vries L, Pradayrol L, Seva C, Tronchere H, Vaysse N. Cholecystokinin and gastrin peptides stimulate ODC activity in a rat pancreatic acinar cell line. Am J Physiol 1989;256: G846-50.
32. Christophe J. Pancreatic tumoral cell line AR4-2J: an amphicrine model. Am J Physiol 1994;266:G963-71.
33. Zhu L, Gunn C, Beckman JS. Bactericidal activity of peroxynitrite. Arch Biochem Biophys 1992;298:452-7.
34. Marthn SJ, Lennon SV, Bonhan AM, Cotter TG. Induction of apoptosis (programmed cell death) in human leukemic HL-60 cells by inhibition of RNA or protein synthesis. J Immunol 1990; 145: 1859-67.
35. Bansal N, Houle A, Melnykovych G. Apoptosis: mode of cell death induced in T cell leukemia lines by dexamethasone and other agents. FASEB J 1991:5:211-6.
36. Lowry OH, Rosebrough NJ, Farr AL. Protein measurement with the folin phenol reagent. J Biol Chem 1951; 127:182-6.
37. Lennon SV, Kilfeather SA, Hallett MB, Campbell AK, Cotter TG. Elevations in cytosolic free Ca2+ are required to trigger apoptosis in human leukaemia cells. Clin Exp Immunol 1992:87:465-71.
38. Magnelli L, Cinelli M, Turchetti A, Chiarugi VP. Apoptosis induction in 32D cells by IL-3 withdrawal is preceded by a drop in the intracellular calcium level. Biochem Biophys Res Commun 1993;194:1394-7.
39. Grynkiewicz G, Poenie M, Tsien RY. A new generation of Ca indicators with greatly improved fluorescence properties. J Biol Chem 1985:260:3440-50.
40. Radi R, Rodriguez M, Castro L, Teller! R. Inhibition of mitochondria! electron transport by peroxynitrite. Arch Biochem Biophys 1994:308:89-95.
41. Rubbo H, Denicola A, Radi R. Peroxynitrite inactivates thiolcontaining enzymes of Trypanosima cruzi energetic metabolism and inhibits cell respiration. Arch Biochem Biophys 1994:308:96102.
42. Salvemini D, Wang ZQ, Bourdon DM, Stern MK, Currie MG, Manning PT. Evidence of peroxynitrite involvement in the carrageenan-induced rat paw edema. Eur J Pharmacol 1996;303: 217-20.
43. Whiteman M, Halliwell B. Protection against peroxynitritedependent tyrosine nitration and alpha 1-antiproteinase inactivation by ascorbic acid. A comparison with other biological antioxidants. Free Radie Res 1996;25:275-83.
44. Walker NI, Winterford CM, Williamson RM, Kerr JF. Ethionineinduced atrophy of rat pancreas involves apoptosis of acinar cells. Pancreas 1993:8:443-9.
45. Home WI, Tsukamoto H. Dietary modulation of alcohol-induced pancreatic injury. Alcohol 1993:10:481-4.
46. Rao MS, Yeldandi AV, Subbarao V, Reddy JK. Role of apoptosis in copper deficiency-induced pancreatic involution in the rat. Am J Pathol 1993;142:1952-7.
47. Walker NI, Winterford CM, Kerr JF. Ultrastructure of the rat pancreas after experimental duct ligation. II. Duct and stromal cell proliferation, differentiation, and deletion. Pancreas 1992;7:42034.
48. Kaiser AM, Saluja A, Sengupta A, Steer ML. Relationship between severity, necrosis and apoptosis in five models of experimental acute pancreatitis. Am J Physiol 1995;269:C 1295-340.
49. Wagner G, Schuch G, Akerboom TPM, Sies H. Transport of ebselen in plasma and its transfer to binding sites in the hepatocyte. Biochem Pharmacol 1994;48:1137-44.
50. Sies H, Ebselen: a glutathione peroxidase mimic. Methods Enzymol 1994:234:476-82.
51. Matsumoto H, Sies H. The reaction of ebselen with peroxynitrite. Clin Res Toxicol 1996;9:262-7.
52. Soussi T, Caron de Fromental C, Mechali M, May P, Kress M. Cloning and characterization of a cDNA from Xenopus laevis coding for a protein homologous to human and murine p53. Oncogene 1987;1:71-81.
53. Kessis TD, Slebos RJ, Nelson WG, et al. Human papillomavirus 16 E6 expression disrupts the P53-mediated cellular response to DNA damage. Proc Nail Acad Sci USA 1993;90:3988-92.
54. Pritsche M, Haessler C, Brandner G. Induction of nuclear accumulation of the tumor-suppressor protein p53 by DNA-damaging agents. Oncogene 1993:8:307-18.
55. Kastan MB, Onyekwere O, Sidransky D, Vogelstein B, Craig RW. Participation of p53 protein in the cellular response to DNA damage. Cancer Res 1991;51:6304-11.
56. Messmer UK, Ankarcrona M, Nicotera P, Brüne B. p53 expression in nitric oxide-induced apoptosis. FEES Lett 1994;355:23-6.
57. Upadhyay S, Li G, Liu H, Chen YQ, Sarkar FH, Kim HR. bcl-2 suppresses expression of p21 WAF/CIP 1 in breast epithelial cells. Cancer Res 1995;55:4520-5.